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FATE

Fate Therapeutics

$13.64 /

+0.07 (+0.52%)

09:27
12/07/19
12/07
09:27
12/07/19
09:27

Fate Therapeutics reports initial clinical data for FT516 and FT50

Fate Therapeutics announced initial clinical data for its FT516 and FT500 off-the-shelf, iPSC-derived natural killer cell product candidates. The first FT516 patient enrolled for the treatment of acute myeloid leukemia was refractory to initial 7+3 induction therapy, multiple subsequent re-induction attempts with chemotherapy, and a combination therapy of venetoclax plus decitabine, the company said. Following outpatient lympho-conditioning, the patient received a first cycle of three once-weekly doses of FT516 as a monotherapy and IL-2 cytokine support. A bone marrow biopsy obtained at day 42 following the completion of the first FT516 treatment cycle showed no morphologic evidence of leukemia and evidence of hematopoietic recovery, it said. Concurrently, no circulating leukemia cells were observed in the peripheral blood, and the patient showed neutrophil recovery without growth factor support. In addition, as of a November 28, 2019 data cutoff, 12 patients have been treated with FT500. No DLTs, FT500-related SAEs or FT500-related Grade greater than or equal to 3 AEs, and no incidents of cytokine release syndrome, neurotoxicity, or graft-versus-host disease, have been reported in 12 patients, the company said. All 12 patients completed the first FT500 treatment cycle of three once-weekly doses

  • 07

    Dec

FATE Fate Therapeutics
$13.64 /

+0.07 (+0.52%)

11/12/19 SunTrust
Fate Therapeutics initiated with a Buy at SunTrust
11/06/19 Mizuho
Mizuho backs Buy rating on Fate Therapeutics after competitor downgrade
11/06/19 Wells Fargo
Wells Fargo downgrades Fate Therapeutics, cuts target to $16 from $24
11/06/19 Wells Fargo
Fate Therapeutics downgraded to Market Perform from Outperform at Wells Fargo

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