Mallinckrodt presents data on infantile spasms predictive model
Mallinckrodt announced findings on the use of its predictive model designed to more quickly identify infants with infantile spasms, a rare seizure disorder that typically occurs between three and seven months of age.1 The study results were reported in a poster presentation titled, "Clinical Pathways Leading to a Diagnosis of Infantile Spasms Using a Claims Database" during the Annual Meeting of the American Epilepsy Society in Baltimore. The company said, "Deductive models developed to identify the combinations of variables that predict IS prior to diagnosis and during the treatment pathway: 557 patients had greater than or equal to 2 symptoms pertaining to IS - seizures, developmental delay, lack of eye contact and lack of muscle tone - and a moderate or high severity ED visit. In this group, 55 percent of patients (n=304) had an IS diagnosis within a median 0.8 months of the triggering event. The most notable deductive combinations focused on pre-diagnosis of IS." Said Chief Medical Officer Tunde Otulana, "We're proud to present this data in support of faster diagnosis of infants during IS Awareness Week, which seeks to raise awareness of the subtle signs of IS that are often overlooked and the urgent need for prompt diagnosis and treatment. Mallinckrodt is committed to conducting research and providing critical services to help caregivers and infants with IS get the proper diagnosis as quickly as possible to enable earlier treatment intervention with the goal of improving long-term outcomes."