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GILD

Gilead

$67.09

1.16 (1.76%)

19:12
12/07/19
12/07
19:12
12/07/19
19:12

Gilead's Kite announces long-term data from ZUMA-1 study in lymphoma

Kite, a Gilead company, announced new data from the ZUMA-1 trial of Yescarta in adult patients with refractory large B-cell lymphoma. These results included updated overall survival data from the pivotal Phase 2 study after three years following a single infusion of Yescarta, as well as an analysis from a separate safety management cohort of patients receiving early steroid intervention for cytokine release syndrome and neurologic events. The data were presented today at the American Society of Hematology Annual Meeting. With a minimum follow-up of three years after a single infusion of Yescarta, median follow-up of 39.1 months, approximately half of patients with refractory large B-cell lymphoma in ZUMA-1 pivotal Phase 2 cohorts were alive, and the median overall survival was 25.8 months. These updated three-year survival data were presented as part of a ZUMA-1 analysis evaluating mechanism of secondary treatment failure following treatment with Yescarta. Updated results from a separate ZUMA-1 safety management study were also presented at the meeting. In this analysis, patients with relapsed or refractory large B-cell lymphoma treated with Yescarta received earlier steroid intervention, beginning when patients experienced Grade 1 neurologic events or experienced Grade 1 CRS with no improvement after three days of supportive care. Patients could receive optional bridging chemotherapy prior to Yescarta infusion. Objective response rate per investigator assessment was 73% in Cohort 4, with 51% of patients achieving a complete response.

  • 07

    Dec

GILD Gilead
$67.09

1.16 (1.76%)

10/25/19
OPCO
10/25/19
NO CHANGE
Target $80
OPCO
Outperform
Gilead price target lowered to $80 from $85 at Oppenheimer
Oppenheimer analyst Hartaj Singh lowered his price target for Gilead to $80 from $85 and maintained an Outperform rating following the company's Q3 earnings report and investor update. While the quarter was in line with consensus estimates, it missed his expectations by 2% on the top line and bottom line due to one-offs for the HIV/HCV franchise, Singh tells investors in a research note. As new management slot in, Singh says he expects further updates on commercial execution and the pipeline, but HIV continues to be strong, HCV is stabilizing, Yescarta still has "surprising" quarterly variations while the filgotinib filing timelines have firmed up.
10/29/19
RBCM
10/29/19
NO CHANGE
RBCM
Top Pick
Gilead design of Phase 2 study of GS-6207 'intriguing,' says RBC Capital
RBC Capital analyst Brian Abrahams noted that details on Gilead's Phase 2 study for its capsid inhibitor, GS-6207, were posted today on clinicaltrials.gov. He calls the design of the study "intriguing," telling investors that the dose and duration suggest that the drug's profile "may look even better than previously disclosed." The analyst, who sees potential for a transformation of the HIV treatment paradigm away from orals, maintains Gilead shares as a Top Pick.
11/12/19
RHCO
11/12/19
INITIATION
Target $70
RHCO
Hold
Gilead initiated with a Hold at SunTrust
SunTrust analyst Robyn Karnauskas initiated coverage of Gilead with a Hold rating and $70 price target. The analyst notes that while the company's HIV portfolio may offer stable revenues for some time, that is not "enough", as Gilead needs more growth catalysts. Karnauskas adds that the market opportunity for Filgotinib may be large, but its uptake could be "slow".
11/15/19
RBCM
11/15/19
NO CHANGE
Target $158
RBCM
Sector Perform
Galapagos price target raised to $158 from $152 at RBC Capital
RBC Capital analyst Brian Abrahams raised his price target on Galapagos (GLPG) to $158 after the company's R&D day, where the management revealed its "expansive plans for bringing new discovery techniques, treatment modalities, preclinical assets, and targeted indications online" by using the cash from its recent Gilead (GILD) deal. While these "aspirations" will take time to mature, the analyst says the plans are "impressive". Abrahams still keeps his Sector Perform rating on Galapagos shares, noting that its nearer term positives of filgotinib commercialization in RA and potential expansion into IB look priced in.

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  • 21

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Alphabet Class A

$1,461.15

11.32 (0.78%)

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$1,462.70

10.76 (0.74%)

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GOOGL

Alphabet Class A

$1,461.15

11.32 (0.78%)

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$1,462.70

10.76 (0.74%)

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WMT

Walmart

$115.30

-0.59 (-0.51%)

11:28
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Walmart chief merchant Steve Bratspies to depart, WSJ reports »

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  • 21

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NFLX

Netflix

$339.15

0.48 (0.14%)

11:25
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Netflix opens new Paris office, boosts investment in France »

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  • 21

    Jan

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AMED

Amedisys

$180.60

-0.59 (-0.33%)

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  • 17

    Jan

IBM

IBM

$137.15

-0.85 (-0.62%)

, PINS

Pinterest

$23.11

0.15 (0.65%)

11:24
01/17/20
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On The Fly
IBM downgrade, Pinterest upgrade among today's top analyst calls »

Check out today's top…

IBM

IBM

$137.15

-0.85 (-0.62%)

PINS

Pinterest

$23.11

0.15 (0.65%)

EBAY

eBay

$35.69

-0.22 (-0.61%)

TWTR

Twitter

$34.11

-0.08 (-0.23%)

SNAP

Snap

$19.10

0.85 (4.66%)

QCOM

Qualcomm

$95.08

3.305 (3.60%)

WDC

Western Digital

$68.69

0.07 (0.10%)

LUV

Southwest

$55.31

0.01 (0.02%)

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NCLH

Norwegian Cruise Line

$59.43

0.84 (1.43%)

11:21
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Breaking Periodicals news story on Norwegian Cruise Line »

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$NSD

NASDAQ Market Internals

$0.00

(0.00%)

11:17
01/17/20
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Technical Analysis
NASDAQ market internals summary »

Volume is above average…

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$NYE

NYSE Market Internals

$0.00

(0.00%)

11:16
01/17/20
01/17
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11:16
Technical Analysis
NYSE market internals summary »

Volume is average for…

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UNIT

Uniti Group

$7.45

-0.49 (-6.17%)

11:15
01/17/20
01/17
11:15
01/17/20
11:15
Options
Uniti Group put volume heavy and directionally bearish »

Bearish flow noted in…

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11:10
01/17/20
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General news
Today's U.S. reports »

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STT

State Street

$84.45

3.445 (4.25%)

11:08
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Periodicals
State Street held talks to find buyer for Currenex, FT reports »

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  • 17

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ERIC

Ericsson

$9.01

-0.075 (-0.83%)

10:55
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10:55
Options
Ericsson put volume heavy and directionally bearish »

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  • 24

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JBLU

JetBlue

$19.30

0.28 (1.47%)

10:45
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Options
JetBlue call volume above normal and directionally bullish »

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  • 23

    Jan

10:40
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ES

Eversource

$87.74

0.01 (0.01%)

, CMS

CMS Energy

$65.28

-0.1 (-0.15%)

10:32
01/17/20
01/17
10:32
01/17/20
10:32
Downgrade
Eversource, CMS Energy, NextEra Energy rating change  »

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ES

Eversource

$87.74

0.01 (0.01%)

CMS

CMS Energy

$65.28

-0.1 (-0.15%)

NEE

NextEra Energy

$251.86

-0.41 (-0.16%)

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  • 22

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TWTR

Twitter

$34.14

-0.05 (-0.15%)

, SNAP

Snap

$19.15

0.9 (4.93%)

10:31
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On The Fly
Analysts bullish on Pinterest, Snap as Twitter gets downgraded to Neutral »

Shares of social media…

TWTR

Twitter

$34.14

-0.05 (-0.15%)

SNAP

Snap

$19.15

0.9 (4.93%)

PINS

Pinterest

$23.30

0.34 (1.48%)

FB

Facebook

$221.31

-0.47 (-0.21%)

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VIX

Volatility Index S&P 500 Options

$0.00

(0.00%)

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Busy week for 50 Cent as another massive block of calls is bought »

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PLAY

Dave & Buster's

$47.28

5.23 (12.44%)

, KKR

KKR

$31.17

0.67 (2.20%)

10:30
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KKR not discussing going hostile on Dave & Buster's, Axios reports »

KKR (KKR) has a…

PLAY

Dave & Buster's

$47.28

5.23 (12.44%)

KKR

KKR

$31.17

0.67 (2.20%)

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  • 20

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VWAGY

Volkswagen

$0.00

(0.00%)

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VW set to acquire 20% stake in Chinese battery maker Guoxuan, Reuters reports »

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