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RHHBY

Roche

$0.00 /

+ (+0.00%)

08:03
12/08/19
12/08
08:03
12/08/19
08:03

Genentech reports data from two Phase III Venclexta studies in leukemia

Genentech, a member of Roche Group, announced updated data from two pivotal Phase III Venclexta studies that highlight Venclexta combination treatments as chemotherapy-free, fixed-duration options that achieve minimal residual disease negativity, in people with chronic lymphocytic leukemia. The pivotal Phase III CLL14 study evaluated the combination of Venclexta plus Gazyva in people with previously untreated CLL, who had co-existing medical conditions. At a median follow-up of more than three years, when all patients had been off therapy for a minimum of two years, Venclexta plus Gazyva showed high response rates, including MRD-negativity. The company said higher rates of MRD-negativity in peripheral blood and bone marrow were observed at the end of treatment in people treated with Venclexta plus Gazyva versus Gazyva plus chlorambucil, respectively. MRD-negativity indicates that no cancer can be detected using a specific, highly sensitive test, and was defined as less than one CLL cell in 10,000 white blood cells, it added. MRD-negativity was observed in 42% of people treated with Venclexta plus Gazyva who achieved a complete response in the peripheral blood, and 14% of people treated with Gazyva plus chlorambucil. Further, the pivotal Phase III Murano study evaluated the combination of Venclexta plus Rituxan in relapsed or refractory CLL. Results showed that Venclexta plus Rituxan significantly reduced the risk of disease progression or death by 81%, Genentech reported. Venclexta plus Rituxan also reduced the risk of death by 59%.

  • 09

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    Dec

RHHBY Roche
$0.00 /

+ (+0.00%)

11/01/19 LEER
Dicerna price target raised to $26 from $22 at SVB Leerink
11/01/19 HCWC
Dicerna HBV deal earlier, on better terms than expected, says H.C. Wainwright
11/14/19 WBLR
William Blair says Ionis fairly valued on Spinraza headwinds
11/19/19 LEER
Dicerna price target raised to $30 from $26 at SVB Leerink

TODAY'S FREE FLY STORIES

Initiation
Slack Technologies initiated with an Overweight at Wells Fargo » 20:45
01/27/20
01/27
20:45
01/27/20
20:45
WORK

Slack Technologies

$20.09 /

-0.505 (-2.45%)

, MSFT

Microsoft

$162.27 /

-2.76 (-1.67%)

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Initiation
Anaplan initiated with an Overweight at Wells Fargo » 20:42
01/27/20
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PLAN

Anaplan

$56.90 /

-1.17 (-2.01%)

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Initiation
Portland General Electric initiated with a Sector Weight at KeyBanc » 20:34
01/27/20
01/27
20:34
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20:34
POR

Portland General Electric

$60.60 /

+0.28 (+0.46%)

KeyBanc analyst Sophie…

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Initiation
Twilio initiated with an Overweight at Wells Fargo » 20:33
01/27/20
01/27
20:33
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TWLO

Twilio

$120.65 /

-0.84 (-0.69%)

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Downgrade
First Mid-Illinois Bancshares downgraded to Neutral from Buy at DA Davidson » 20:31
01/27/20
01/27
20:31
01/27/20
20:31
FMBH

First Mid-Illinois Bancshares

$34.10 /

+0.08 (+0.24%)

DA Davidson analyst David…

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Initiation
HubSpot initiated with an Equal Weight at Wells Fargo » 20:29
01/27/20
01/27
20:29
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20:29
HUBS

HubSpot

$182.55 /

-1.74 (-0.94%)

Wells Fargo analyst…

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Initiation
Inspire Medical initiated with an Underperform at Oppenheimer » 20:25
01/27/20
01/27
20:25
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20:25
INSP

Inspire Medical

$78.50 /

-2.22 (-2.75%)

Oppenheimer analyst Suraj…

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Earnings
Notable companies reporting before tomorrow's open » 20:25
01/27/20
01/27
20:25
01/27/20
20:25
PFE

Pfizer

$40.16 /

+0.34 (+0.85%)

, UTX

United Technologies

$151.12 /

-2.05 (-1.34%)

, LMT

Lockheed Martin

$432.31 /

-0.31 (-0.07%)

, MMM

3M

$175.70 /

-2.48 (-1.39%)

, HCA

HCA Healthcare

$141.57 /

-1.88 (-1.31%)

, PCAR

Paccar

$75.15 /

-1.64 (-2.14%)

, MKC

McCormick

$172.74 /

+0.005 (+0.00%)

, NUE

Nucor

$49.21 /

-1.13 (-2.24%)

, PHM

PulteGroup

$44.34 /

+0.62 (+1.42%)

, LEA

Lear

$130.47 /

-3.235 (-2.42%)

, AOS

A.O. Smith

$43.82 /

-1.63 (-3.59%)

, HOG

Harley-Davidson

$34.86 /

-0.37 (-1.05%)

, GPK

Graphic Packaging

$16.42 /

-0.01 (-0.06%)

, CIT

CIT Group

$45.02 /

-0.975 (-2.12%)

Notable companies…

Notable companies reporting before tomorrow's open, with earnings consensus, include Pfizer Inc. (PFE), consensus 57C... United Technologies (UTX), consensus $1.84... Lockheed Martin (LMT), consensus $5.02... 3M (MMM), consensus $2.10... HCA Healthcare (HCA), consensus $3.09... PACCAR (PCAR), consensus $1.51... McCormick (MKC), consensus $1.61... Nucor (NUE), consensus 31C... PulteGroup (PHM), consensus $1.09... Lear Corp. (LEA), consensus $2.20... A. O. Smith (AOS), consensus 59C... Harley-Davidson (HOG), consensus 9C... Graphic Packaging (GPK), consensus 23C... CIT Group (CIT), consensus $1.11.

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Upgrade
Garmin upgraded to Neutral from Underperform at Credit Suisse » 20:15
01/27/20
01/27
20:15
01/27/20
20:15
GRMN

Garmin

$98.40 /

-1.17 (-1.18%)

Credit Suisse analyst…

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Hot Stocks
SPDR Gold Shares holdings fall to 899.41MT from 900.58MT » 20:06
01/27/20
01/27
20:06
01/27/20
20:06
GLD

SPDR Gold Shares

$149.01 /

+1.05 (+0.71%)

This is the first decline…

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Hot Stocks
Embraer, Boeing get approval for partnership from Brazil's CADE » 19:24
01/27/20
01/27
19:24
01/27/20
19:24
BA

Boeing

$316.61 /

-6.43 (-1.99%)

, ERJ

Embraer

$17.35 /

-0.485 (-2.72%)

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Hot Stocks
Fly Intel: After Hours Movers » 18:57
01/27/20
01/27
18:57
01/27/20
18:57
GGG

Graco

$51.41 /

-0.605 (-1.16%)

, BRO

Brown & Brown

$41.70 /

-0.145 (-0.35%)

, IPAR

Inter Parfums

$70.67 /

-1.33 (-1.85%)

, XLRN

Acceleron

$52.83 /

+0.81 (+1.56%)

, SURF

Surface Oncology

$2.93 /

-0.13 (-4.25%)

, MNOV

MediciNova

$6.10 /

-0.26 (-4.09%)

, LAUR

Laureate Education

$17.70 /

+0.04 (+0.23%)

, FFIV

F5 Networks

$132.71 /

-3.14 (-2.31%)

, RMBS

Rambus

$14.57 /

-0.38 (-2.54%)

, JNPR

Juniper

$24.46 /

-0.12 (-0.49%)

, PKI

PerkinElmer

$98.74 /

-1.075 (-1.08%)

, JJSF

J & J Snack Foods

$184.54 /

-2.31 (-1.24%)

, ALEC

Alector

$25.72 /

+1.17 (+4.77%)

, DNLI

Denali Therapeutics

$27.97 /

+3.29 (+13.33%)

UP AFTER EARNINGS: Graco…

UP AFTER EARNINGS: Graco (GGG) up 4.6%... Brown&Brown (BRO) up 2.0%... Inter Parfums (IPAR) up 1.0%. ALSO HIGHER: Acceleron Pharma (XLRN) up 66.1% after announcing its sotatercept trial met endpoints... Surface Oncology (SURF) up 13.8% after getting FDA clearance for SRF617, SRF388 INDs... MediciNova (MNOV) up 11.3% after getting notice of intention to grant patent for MN-001 in Europe... Laureate Education (LAUR) up 4.5% after announcing plans to explore strategic alternatives. DOWN AFTER EARNINGS: F5 Networks (FFIV) down 4.5%... Rambus (RMBS) down 3.2%... Juniper (JNPR) down 2.9%... PerkinElmer (PKI) down 2.7%... J&J Snack Foods (JJSF) down 2.0%. ALSO LOWER: Alector (ALEC) down 2.8% after equity offering... Denali Therapeutics (DNLI) down 2.7% after equity offering. Movers as of 18:45ET.

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  • 30
    Jan
  • 29
    Jan
Hot Stocks
Intuit urges holders to reject mini-tender offer by TRC Capital » 18:50
01/27/20
01/27
18:50
01/27/20
18:50
INTU

Intuit

$283.76 /

-4.41 (-1.53%)

Intuit said it has been…

Intuit said it has been notified of an unsolicited mini-tender offer by TRC Capital Investment Corporation to purchase up to 400,000 shares of Intuit common stock at a price of $270.00 per share in cash. TRC's offer price is approximately 4.54 percent lower than the closing price of Intuit common stock on Jan. 17, 2020, the last trading day prior to the commencement of the offer, and approximately 6.28 percent lower than closing price of Intuit common stock on Jan. 24, 2020, the last trading day prior to this release. Intuit does not endorse TRC's offer and recommends that Intuit shareholders reject the offer and not tender their shares in response to TRC's unsolicited offer. The mini-tender offer is at a price below the market price of shares of Intuit's common stock (as of today's date) and is subject to numerous conditions, including TRC's ability to obtain financing. Intuit is not associated in any way with TRC, its mini-tender offer or the offer documentation. TRC has made many similar unsolicited mini-tender offers for shares of other publicly traded companies. Mini-tender offers seek to acquire less than 5 percent of a company's outstanding shares, thereby avoiding many disclosure and procedural requirements of the Securities and Exchange Commission that apply to tender offers for more than 5 percent of a company's outstanding shares. As a result, mini-tender offers may not provide investors with the same level of protections as provided in larger tender offers under U.S. securities laws, the company noted.

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Hot Stocks
Ballard Power says now powers fuel cell EVs for 30M kilometers » 18:46
01/27/20
01/27
18:46
01/27/20
18:46
BLDP

Ballard Power

$9.14 /

-0.56 (-5.77%)

Ballard Power Systems…

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Hot Stocks
Merit Medical confirms notice of Starboard director nominations » 18:21
01/27/20
01/27
18:21
01/27/20
18:21
MMSI

Merit Medical

$36.05 /

-0.55 (-1.50%)

Merit Medical Systems…

Merit Medical Systems confirmed that it has received notice from Starboard Value LP that it has nominated seven individuals to stand for election as directors at Merit's 2020 Annual Meeting of Shareholders. In its notice to Merit, Starboard indicated that it intends to withdraw four of its seven nominees if there are only three seats on Merit's Board to be filled at the Annual Meeting. The date of the Annual Meeting has not yet been set. Members of Merit's Board and management team recently had an initial discussion with representatives of Starboard, and Merit looks forward to further engagement to better understand Starboard's ideas. Merit values constructive input from all shareholders toward the shared goal of enhancing stakeholder value, the comapny said.

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Hot Stocks
MediciNova gets notice of intention to grant patent for MN-001 from EPO » 18:02
01/27/20
01/27
18:02
01/27/20
18:02
MNOV

MediciNova

$6.10 /

-0.26 (-4.09%)

MediciNov announced that…

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Periodicals
JPMorgan to keep 2019 bonuses flat for traders, bankers, Bloomberg reports » 18:01
01/27/20
01/27
18:01
01/27/20
18:01
JPM

JPMorgan

$132.00 /

-1.14 (-0.86%)

JPMorgan is keeping…

JPMorgan is keeping annual bonuses at its corporate and investment bank approximately flat for 2019, Bloomberg's Michelle Davis reports. The company's decision, described by people briefed on the matter, came after the unit notched its best year since at least 2011. Most of the workers were told about their payouts last week, said one of the people. Reference Link

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Periodicals
CBS says All Access achieved record month of sign-ups, TechCrunch says » 17:59
01/27/20
01/27
17:59
01/27/20
17:59
VIAC

ViacomCBS

$35.13 /

-0.65 (-1.82%)

, VIACA

ViacomCBS

$39.51 /

+0.4 (+1.02%)

CBS's streaming…

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Hot Stocks
U.S. FDA approves Trijardy XR for adults with type 2 diabetes » 17:38
01/27/20
01/27
17:38
01/27/20
17:38
LLY

Eli Lilly

$138.38 /

-0.71 (-0.51%)

The U.S. FDA has approved…

The U.S. FDA has approved Trijardy XR to lower blood sugar in adults with type 2 diabetes, along with diet and exercise. Trijardy XR provides three type 2 diabetes medicines in one pill, including Jardiance, Tradjenta, and metformin hydrochloride extended release. Trijardy XR is marketed by Boehringer Ingelheim Pharmaceuticals and Eli Lilly and Company.

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Conference/Events
Morgan Stanley China Economist to hold an analyst/industry conference call » 17:37
01/27/20
01/27
17:37
01/27/20
17:37

Chief Economist &…

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Hot Stocks
Juniper CFO says 'comfortable' with current Street revenue estimate for FY20 » 17:35
01/27/20
01/27
17:35
01/27/20
17:35
JNPR

Juniper

$24.46 /

-0.12 (-0.49%)

Says looking for FY20…

Says looking for FY20 revenue growth of about 1%. Sees FY20 gross margins "flat to slightly up". Comments taken from Q4 earnings conference call Q/A.

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Earnings
Southern Missouri Bancorp reports Q2 EPS 84c, consensus 81c » 17:33
01/27/20
01/27
17:33
01/27/20
17:33
SMBC

Southern Missouri Bancorp

$36.50 /

+0.1 (+0.27%)

Reports Q2 provision for…

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Recommendations
Momenta price target raised to $43 from $29 at Stifel » 17:30
01/27/20
01/27
17:30
01/27/20
17:30
MNTA

Momenta

$28.82 /

+0.62 (+2.20%)

Stifel analyst Derek…

Stifel analyst Derek Archila reiterated a Buy rating on Momenta (MNTA) and raised his price target on shares to $43 from $29, as he believes the shares have "more upside from here." The price target raise follows the recent positive update on M254, which the analyst said "could put pressure on the large traditional IVIG manufacturers to strike a partnership with Momenta or, for one to outright acquire the company."

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Hot Stocks
Instructure says 'strongly disagrees' with conclusion reached by ISS » 17:29
01/27/20
01/27
17:29
01/27/20
17:29
INST

Instructure

$47.97 /

+0.135 (+0.28%)

Instructure issued the…

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Syndicate
Allegiance Bancshares files $225M mixed securities shelf  17:27
01/27/20
01/27
17:27
01/27/20
17:27
ABTX

Allegiance Bancshares

$36.48 /

-0.3 (-0.82%)

 
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