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IMV

IMV Inc.

$2.92 /

+0.07 (+2.46%)

12:30
12/08/19
12/08
12:30
12/08/19
12:30

IMV announces updated results from Phase 2 study of DPX-Survivac

IMV Inc. announced that updated results from SPiReL, an ongoing Phase 2 investigator-sponsored study of DPX-Survivac in combination with pembrolizumab in patients with recurrent/refractory diffuse large B-cell lymphoma, were presented in a poster session at the American Society of Hematology Annual Meeting. The poster, which included additional data collected between the abstract submission and the presentation, "continued to demonstrate a favorable therapeutic profile and treatment-associated clinical benefit in r/r DLBCL patients who received the DPX-Survivac combination regimen," the company said. Highlights of this preliminary data are: 7/9 evaluable subjects exhibited clinical benefit, including three complete responses and two (22.2%) partial responses; Reproducible survivin-specific T cell responses observed in all subjects that achieved clinical responses on treatment; One subject, who received three prior lines of systemic therapies and failed autologous stem cell transplant, reached a complete response at the first on-study scan following treatment with the DPX-Survivac combination regimen and remains free of disease recurrence after completing the study; and clinical benefits and favorable toxicity profile observed in a heterogenous population of r/r DLBCL patients, including patients of advanced age and/or with comorbidities, who are more susceptible to adverse effects and more difficult to treat, IMV said. Joanne Schindler, Chief Medical Officer of IMV, added, "These data further validate DPX-Survivac's novel mechanism, extending previously documented results in solid cancers now to survivin-expressing hematologic malignancies, and support the hypothesis that our lead candidate works well in combination with checkpoint inhibitors. We believe this represents a potentially meaningful alternative to more toxic chemotherapy regimens; and, with this foundation, we look forward to topline results from this study as we prepare to launch an IMV-sponsored study in r/r DLBCL in 2020."

IMV IMV Inc.
$2.92 /

+0.07 (+2.46%)

10/28/19
Fly Intel: Top five analyst initiations
11/25/19 OPCO
IMV Inc. initiated with an Outperform at Oppenheimer
11/26/19 OPCO
IMV initiated with an Outperform and C$9 target at Oppenheimer
11/26/19
Fly Intel: Top five analyst initiations

TODAY'S FREE FLY STORIES

Initiation
Slack Technologies initiated with an Overweight at Wells Fargo » 20:45
01/27/20
01/27
20:45
01/27/20
20:45
WORK

Slack Technologies

$20.09 /

-0.505 (-2.45%)

, MSFT

Microsoft

$162.27 /

-2.76 (-1.67%)

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Initiation
Anaplan initiated with an Overweight at Wells Fargo » 20:42
01/27/20
01/27
20:42
01/27/20
20:42
PLAN

Anaplan

$56.90 /

-1.17 (-2.01%)

Wells Fargo analyst…

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Initiation
Portland General Electric initiated with a Sector Weight at KeyBanc » 20:34
01/27/20
01/27
20:34
01/27/20
20:34
POR

Portland General Electric

$60.60 /

+0.28 (+0.46%)

KeyBanc analyst Sophie…

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Initiation
Twilio initiated with an Overweight at Wells Fargo » 20:33
01/27/20
01/27
20:33
01/27/20
20:33
TWLO

Twilio

$120.65 /

-0.84 (-0.69%)

Wells Fargo analyst…

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Downgrade
First Mid-Illinois Bancshares downgraded to Neutral from Buy at DA Davidson » 20:31
01/27/20
01/27
20:31
01/27/20
20:31
FMBH

First Mid-Illinois Bancshares

$34.10 /

+0.08 (+0.24%)

DA Davidson analyst David…

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Initiation
HubSpot initiated with an Equal Weight at Wells Fargo » 20:29
01/27/20
01/27
20:29
01/27/20
20:29
HUBS

HubSpot

$182.55 /

-1.74 (-0.94%)

Wells Fargo analyst…

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Initiation
Inspire Medical initiated with an Underperform at Oppenheimer » 20:25
01/27/20
01/27
20:25
01/27/20
20:25
INSP

Inspire Medical

$78.50 /

-2.22 (-2.75%)

Oppenheimer analyst Suraj…

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Earnings
Notable companies reporting before tomorrow's open » 20:25
01/27/20
01/27
20:25
01/27/20
20:25
PFE

Pfizer

$40.16 /

+0.34 (+0.85%)

, UTX

United Technologies

$151.12 /

-2.05 (-1.34%)

, LMT

Lockheed Martin

$432.31 /

-0.31 (-0.07%)

, MMM

3M

$175.70 /

-2.48 (-1.39%)

, HCA

HCA Healthcare

$141.57 /

-1.88 (-1.31%)

, PCAR

Paccar

$75.15 /

-1.64 (-2.14%)

, MKC

McCormick

$172.74 /

+0.005 (+0.00%)

, NUE

Nucor

$49.21 /

-1.13 (-2.24%)

, PHM

PulteGroup

$44.34 /

+0.62 (+1.42%)

, LEA

Lear

$130.47 /

-3.235 (-2.42%)

, AOS

A.O. Smith

$43.82 /

-1.63 (-3.59%)

, HOG

Harley-Davidson

$34.86 /

-0.37 (-1.05%)

, GPK

Graphic Packaging

$16.42 /

-0.01 (-0.06%)

, CIT

CIT Group

$45.02 /

-0.975 (-2.12%)

Notable companies…

Notable companies reporting before tomorrow's open, with earnings consensus, include Pfizer Inc. (PFE), consensus 57C... United Technologies (UTX), consensus $1.84... Lockheed Martin (LMT), consensus $5.02... 3M (MMM), consensus $2.10... HCA Healthcare (HCA), consensus $3.09... PACCAR (PCAR), consensus $1.51... McCormick (MKC), consensus $1.61... Nucor (NUE), consensus 31C... PulteGroup (PHM), consensus $1.09... Lear Corp. (LEA), consensus $2.20... A. O. Smith (AOS), consensus 59C... Harley-Davidson (HOG), consensus 9C... Graphic Packaging (GPK), consensus 23C... CIT Group (CIT), consensus $1.11.

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Upgrade
Garmin upgraded to Neutral from Underperform at Credit Suisse » 20:15
01/27/20
01/27
20:15
01/27/20
20:15
GRMN

Garmin

$98.40 /

-1.17 (-1.18%)

Credit Suisse analyst…

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Hot Stocks
SPDR Gold Shares holdings fall to 899.41MT from 900.58MT » 20:06
01/27/20
01/27
20:06
01/27/20
20:06
GLD

SPDR Gold Shares

$149.01 /

+1.05 (+0.71%)

This is the first decline…

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Hot Stocks
Embraer, Boeing get approval for partnership from Brazil's CADE » 19:24
01/27/20
01/27
19:24
01/27/20
19:24
BA

Boeing

$316.61 /

-6.43 (-1.99%)

, ERJ

Embraer

$17.35 /

-0.485 (-2.72%)

Boeing (BA) and Embraer…

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Hot Stocks
Fly Intel: After Hours Movers » 18:57
01/27/20
01/27
18:57
01/27/20
18:57
GGG

Graco

$51.41 /

-0.605 (-1.16%)

, BRO

Brown & Brown

$41.70 /

-0.145 (-0.35%)

, IPAR

Inter Parfums

$70.67 /

-1.33 (-1.85%)

, XLRN

Acceleron

$52.83 /

+0.81 (+1.56%)

, SURF

Surface Oncology

$2.93 /

-0.13 (-4.25%)

, MNOV

MediciNova

$6.10 /

-0.26 (-4.09%)

, LAUR

Laureate Education

$17.70 /

+0.04 (+0.23%)

, FFIV

F5 Networks

$132.71 /

-3.14 (-2.31%)

, RMBS

Rambus

$14.57 /

-0.38 (-2.54%)

, JNPR

Juniper

$24.46 /

-0.12 (-0.49%)

, PKI

PerkinElmer

$98.74 /

-1.075 (-1.08%)

, JJSF

J & J Snack Foods

$184.54 /

-2.31 (-1.24%)

, ALEC

Alector

$25.72 /

+1.17 (+4.77%)

, DNLI

Denali Therapeutics

$27.97 /

+3.29 (+13.33%)

UP AFTER EARNINGS: Graco…

UP AFTER EARNINGS: Graco (GGG) up 4.6%... Brown&Brown (BRO) up 2.0%... Inter Parfums (IPAR) up 1.0%. ALSO HIGHER: Acceleron Pharma (XLRN) up 66.1% after announcing its sotatercept trial met endpoints... Surface Oncology (SURF) up 13.8% after getting FDA clearance for SRF617, SRF388 INDs... MediciNova (MNOV) up 11.3% after getting notice of intention to grant patent for MN-001 in Europe... Laureate Education (LAUR) up 4.5% after announcing plans to explore strategic alternatives. DOWN AFTER EARNINGS: F5 Networks (FFIV) down 4.5%... Rambus (RMBS) down 3.2%... Juniper (JNPR) down 2.9%... PerkinElmer (PKI) down 2.7%... J&J Snack Foods (JJSF) down 2.0%. ALSO LOWER: Alector (ALEC) down 2.8% after equity offering... Denali Therapeutics (DNLI) down 2.7% after equity offering. Movers as of 18:45ET.

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  • 30
    Jan
  • 29
    Jan
Hot Stocks
Intuit urges holders to reject mini-tender offer by TRC Capital » 18:50
01/27/20
01/27
18:50
01/27/20
18:50
INTU

Intuit

$283.76 /

-4.41 (-1.53%)

Intuit said it has been…

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Hot Stocks
Ballard Power says now powers fuel cell EVs for 30M kilometers » 18:46
01/27/20
01/27
18:46
01/27/20
18:46
BLDP

Ballard Power

$9.14 /

-0.56 (-5.77%)

Ballard Power Systems…

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Hot Stocks
Merit Medical confirms notice of Starboard director nominations » 18:21
01/27/20
01/27
18:21
01/27/20
18:21
MMSI

Merit Medical

$36.05 /

-0.55 (-1.50%)

Merit Medical Systems…

Merit Medical Systems confirmed that it has received notice from Starboard Value LP that it has nominated seven individuals to stand for election as directors at Merit's 2020 Annual Meeting of Shareholders. In its notice to Merit, Starboard indicated that it intends to withdraw four of its seven nominees if there are only three seats on Merit's Board to be filled at the Annual Meeting. The date of the Annual Meeting has not yet been set. Members of Merit's Board and management team recently had an initial discussion with representatives of Starboard, and Merit looks forward to further engagement to better understand Starboard's ideas. Merit values constructive input from all shareholders toward the shared goal of enhancing stakeholder value, the comapny said.

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Hot Stocks
MediciNova gets notice of intention to grant patent for MN-001 from EPO » 18:02
01/27/20
01/27
18:02
01/27/20
18:02
MNOV

MediciNova

$6.10 /

-0.26 (-4.09%)

MediciNov announced that…

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Periodicals
JPMorgan to keep 2019 bonuses flat for traders, bankers, Bloomberg reports » 18:01
01/27/20
01/27
18:01
01/27/20
18:01
JPM

JPMorgan

$132.00 /

-1.14 (-0.86%)

JPMorgan is keeping…

JPMorgan is keeping annual bonuses at its corporate and investment bank approximately flat for 2019, Bloomberg's Michelle Davis reports. The company's decision, described by people briefed on the matter, came after the unit notched its best year since at least 2011. Most of the workers were told about their payouts last week, said one of the people. Reference Link

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Periodicals
CBS says All Access achieved record month of sign-ups, TechCrunch says » 17:59
01/27/20
01/27
17:59
01/27/20
17:59
VIAC

ViacomCBS

$35.13 /

-0.65 (-1.82%)

, VIACA

ViacomCBS

$39.51 /

+0.4 (+1.02%)

CBS's streaming…

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Hot Stocks
U.S. FDA approves Trijardy XR for adults with type 2 diabetes » 17:38
01/27/20
01/27
17:38
01/27/20
17:38
LLY

Eli Lilly

$138.38 /

-0.71 (-0.51%)

The U.S. FDA has approved…

The U.S. FDA has approved Trijardy XR to lower blood sugar in adults with type 2 diabetes, along with diet and exercise. Trijardy XR provides three type 2 diabetes medicines in one pill, including Jardiance, Tradjenta, and metformin hydrochloride extended release. Trijardy XR is marketed by Boehringer Ingelheim Pharmaceuticals and Eli Lilly and Company.

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Conference/Events
Morgan Stanley China Economist to hold an analyst/industry conference call » 17:37
01/27/20
01/27
17:37
01/27/20
17:37

Chief Economist &…

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Hot Stocks
Juniper CFO says 'comfortable' with current Street revenue estimate for FY20 » 17:35
01/27/20
01/27
17:35
01/27/20
17:35
JNPR

Juniper

$24.46 /

-0.12 (-0.49%)

Says looking for FY20…

Says looking for FY20 revenue growth of about 1%. Sees FY20 gross margins "flat to slightly up". Comments taken from Q4 earnings conference call Q/A.

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Earnings
Southern Missouri Bancorp reports Q2 EPS 84c, consensus 81c » 17:33
01/27/20
01/27
17:33
01/27/20
17:33
SMBC

Southern Missouri Bancorp

$36.50 /

+0.1 (+0.27%)

Reports Q2 provision for…

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Recommendations
Momenta price target raised to $43 from $29 at Stifel » 17:30
01/27/20
01/27
17:30
01/27/20
17:30
MNTA

Momenta

$28.82 /

+0.62 (+2.20%)

Stifel analyst Derek…

Stifel analyst Derek Archila reiterated a Buy rating on Momenta (MNTA) and raised his price target on shares to $43 from $29, as he believes the shares have "more upside from here." The price target raise follows the recent positive update on M254, which the analyst said "could put pressure on the large traditional IVIG manufacturers to strike a partnership with Momenta or, for one to outright acquire the company."

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Hot Stocks
Instructure says 'strongly disagrees' with conclusion reached by ISS » 17:29
01/27/20
01/27
17:29
01/27/20
17:29
INST

Instructure

$47.97 /

+0.135 (+0.28%)

Instructure issued the…

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Syndicate
Allegiance Bancshares files $225M mixed securities shelf  17:27
01/27/20
01/27
17:27
01/27/20
17:27
ABTX

Allegiance Bancshares

$36.48 /

-0.3 (-0.82%)

 
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