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BPMC

Blueprint Medicines

$78.50

3.92 (5.26%)

18:34
12/08/19
12/08
18:34
12/08/19
18:34

Piper says 'jury still out' on Blueprint Medicines' avapritinib after ASH data

Piper Jaffray analyst Christopher Raymond noted that Blueprint Medicines reported initial data from its PIONEER Phase 2 study of avapritinib in indolent systemic mastocytosis, or ISM, along with additional data from EXPLORER, its Phase 1 study of avapritinib in advanced SM, or ASM, at this weekend's ASH meeting. While "bulls can take comfort from PIONEER's safety update," Raymond said the "jury is still out, especially in ISM," given that Blueprint provided no improvements in symptomatic scores despite a median 12-week follow up. Raymond keeps a Neutral rating on Blueprint Medicines shares.

  • 08

    Dec

  • 08

    Dec

BPMC Blueprint Medicines
$78.50

3.92 (5.26%)

11/06/19
RAJA
11/06/19
UPGRADE
Target $112
RAJA
Strong Buy
Blueprint Medicines upgraded to Strong Buy from Outperform at Raymond James
Raymond James analyst Dane Leone upgraded Blueprint Medicines to Strong Buy from Outperform with a $112 price target.
11/06/19
RAJA
11/06/19
UPGRADE
Target $112
RAJA
Strong Buy
Blueprint Medicines upgraded to Strong Buy at Raymond James
Raymond James analyst Dane Leone upgraded Blueprint Medicines to Strong Buy from Outperform with a price target of $112, up from $106, following the company's R&D update in NYC. In a research note to investors, Leone says the event supported key tenets to the thesis around systemic mastocytosis, or SM, and specifically provided clinical follow-up for the indolent systemic mastocytosis group that had been treated within the EXPLORER study, a discussion with a SM KOL that provided feedback on clinical experience with avapritinib, and a first look at a next gen D816V targeted drug that will submit an IND during 1H20.
11/06/19
11/06/19
UPGRADE

Fly Intel: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Rollins (ROL) upgraded to Hold from Sell at Stifel with analyst Michael Hoffman saying the company has "reinvigorated" organic growth and when combined with more rapid consolidation of domestic Pest Control, it can likely drive double digit free cash flow growth for the next five years. 2. Tenet (THC) upgraded to Outperform from Neutral at Credit Suisse with analyst A.J. Rice saying he "solid trends" in the company's hospital business, including improving volumes, steady pricing growth, and "effective management" of underlying cost growth. 3. Blueprint Medicines (BPMC) upgraded to Strong Buy from Outperform at Raymond James with analyst Dane Leone citing the company's R&D update in NYC. 4. Lowe's (LOW) upgraded to Outperform from Neutral at Credit Suisse with analyst Seth Sigman saying the company's relative valuation versus closest peer Home Depot (HD) is near its trough level, industry demand is improving and there are "multiple sales/margin levers ahead." 5. Artisan Partners (APAM) upgraded to Buy from Neutral at Citi with analyst William Katz saying he sees potential for the company's net new assets to inflect positively into 2021, which he thinks should be enough to drive modest multiple expansion. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
12/02/19
DBAB
12/02/19
NO CHANGE
Target $75
DBAB
Hold
Deutsche Bank initiates Sell Catalyst Call on Blueprint Medicines ahead of data
In a note sent before the open, Deutsche Bank analyst Konstantinos Aprilakis said he has initiated a Sell Catalyst Call on Blueprint Medicines ahead of data from its Phase 2 PIONEER study of avapritinib in indolent mastocytosis, or ISM, which is expected at the upcoming ASH meeting on December 7-10. Despite management stating at last month's R&D day that there have been no discontinuations due to side effects, he does not favor the risk-reward going into this trial readout, Aprilakis told investors. He believes that if there are any signs of cognitive toxicity at the lower doses in the PIONEER study, it could "cast further doubt on avapritinib's future in ISM," the analyst added. While he is making a short-term sell call, Aprilakis has a Hold rating on Blueprint shares with a price target of $75. In morning trading, Blueprint shares are down $5.89, or 7.2%, to $76.15.

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