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SMMT

Summit Therapeutics

$1.52

-0.015 (-0.98%)

07:20
12/17/19
12/17
07:20
12/17/19
07:20

Summit Therapeutics expects data for Phase 3 ridinilazole program in 2H21

The company said, "Ridinilazole for C. difficile Infection: Ri-CoDIFy Phase 3 landmark clinical trials aim to support registration of the precision antibiotic ridinilazole in the US and other territories, and its adoption as a first-line treatment for CDI by: showing superiority over the current standard of care, vancomycin, using a composite endpoint measuring sustained clinical response; generating health economic data to help support ridinilazole's commercial launch, if approved; and undertaking deep microbiome analyses to evaluate ridinilazole's preservation of the gut microbiome. The Phase 3 clinical programme remains on track for expected reporting of top-line data in the second half of 2021. The trials had enrolled a total of 128 patients as at the end of November 2019 with over two thirds of the 300 planned clinical trials sites having been opened. Reported new Phase 2 clinical trial data that showed ridinilazole improved patients' quality of life compared to vancomycin, including statistically significant improvements in measurements of physical and mental health. Additional data from the Phase 2 clinical trial provided mechanistic insights into how ridinilazole preserved the diversity of the gut microbiome in patients with CDI to maintain the balance of the metabolome of active chemicals made or modified by gut bacteria that help prevent C. difficile recurrence. These new results were reported at the ID Week Conference held in Washington DC in October 2019. Commercial and medical affairs hires have been made in the United States to support work to prepare for a potential launch and to secure future market access for ridinilazole, if approved."

TODAY'S FREE FLY STORIES

OMI

Owens & Minor

$6.40

0.88 (15.94%)

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MNK

Mallinckrodt

$6.14

0.935 (17.96%)

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CSS

CSS Industries

$9.35

4.65 (98.94%)

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AMRN

Amarin

$21.49

1.58 (7.94%)

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0.2 (0.47%)

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NIO Inc.

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AIG

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AON

Aon plc

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BRO

Brown & Brown

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MMC

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WLTW

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0.67 (0.33%)

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TRIP

TripAdvisor

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-0.38 (-1.23%)

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  • 13

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YARIY

Yara

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VALE

Vale

$13.37

-0.275 (-2.02%)

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Charges filed against Vale, TUV SUD for deadly dam collapse, WSJ reports »

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UBER

Uber

$36.94

1.82 (5.18%)

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  • 06

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LVS

Las Vegas Sands

$70.95

-3.12 (-4.21%)

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SRRA

Sierra Oncology

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INTC

Intel

$60.68

1.1 (1.85%)

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COST

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DG

Dollar General

$157.97

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LL

Lumber Liquidators

$8.46

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MS

Morgan Stanley

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  • 22

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LRCX

Lam Research

$311.12

3.14 (1.02%)

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  • 29

    Jan

$NSD

NASDAQ Market Internals

$0.00

(0.00%)

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$NYE

NYSE Market Internals

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COLM

Columbia Sportswear

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1.51 (1.58%)

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VF Corp.

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COLM

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$97.10

1.51 (1.58%)

VFC

VF Corp.

$94.20

-0.05 (-0.05%)

KTB

Kontoor Brands

$42.31

0.595 (1.43%)

YETI

Yeti

$36.33

2.1 (6.13%)

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  • 23

    Jan

  • 06

    Feb

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