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ZGNX

Zogenix

$52.71 /

+2.69 (+5.38%)

19:08
12/17/19
12/17
19:08
12/17/19
19:08

Zogenix's Fintepla shows significant reduction in convulsive seizure frequency

Zogenix announced that The Lancet has published the results of its Phase 3 clinical trial, Study 1, of the company's investigational drug, Fintepla in children and young adults with Dravet syndrome, a rare, severe infantile-onset epilepsy characterized by frequent, disabling seizures that are difficult to treat with existing anti-epileptic drugs. The study showed that both doses of FINTEPLA, when added to the patients' existing treatment regimens, provided a significant reduction in convulsive seizure frequency compared to placebo. Results showed that patients taking FINTEPLA at 0.7 mg/kg/day achieved a 62.3% greater reduction in mean monthly convulsive seizure frequency compared to placebo. The same analysis for the group treated at 0.2 mg/kg/day versus placebo was a key secondary endpoint, with results showing a 32.4% greater reduction in mean monthly convulsive seizure frequency compared to placebo. During the treatment period, the median reduction in seizure frequency was 74.9% in the 0.7 mg/kg/day group, 42.3% in the 0.2 mg/kg/day group, and 19.2% in the placebo group. In addition to the seizure frequency data described above, more patients treated with FINTEPLA during the study achieved a clinically meaningful (greater than or equal to 50%) reduction in convulsive seizure frequency compared to placebo.

  • 25

    Mar

ZGNX Zogenix
$52.71 /

+2.69 (+5.38%)

12/06/19 Piper Sandler
2020 looking to be 'transformational year' for Zogenix, says Piper Jaffray
10/21/19 Needham
Zogenix initiated with a Buy at Needham
08/26/19 Piper Sandler
Zogenix should be bought on weakness from Modis deal, says Piper Jaffray
06/28/19 Mizuho
Zogenix price target raised to $65 from $58 at Mizuho

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Engie approaches Ameresco over acquisition interest, Reuters reports » 11:56
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Initiation
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