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AXGT

Axovant

$4.98

-0.08 (-1.58%)

06:52
01/13/20
01/13
06:52
01/13/20
06:52

Axovant announces recent progress in gene therapy programs

Axovant Gene Therapies announced recent progress in its gene therapy programs, including a 12-month update on its Parkinson's program. Major 2019 Accomplishments and Upcoming 2020 Milestones include: at 12 months post-dosing, patients in the first dose cohort demonstrated an average 22-point change from baseline in motor function as assessed by the UPDRS Part III "OFF" score, which represents a 37% improvement. Individual patient improvements were 24-points and 20-points, respectively. Reported data from the first child dosed with AXO-AAV-GM1 under an expanded access protocol, which suggested tolerability and clinical improvement between baseline and 6-months after vector administration with no reports of serious adverse events attributable to the gene therapy. In October 2019, at the European Society of Gene and Cell Therapy 27th Annual Congress, Dr. Terry Flotte presented evidence of clinical disease stabilization in two patients dosed with AXO-AAV-GM2 under an investigator-initiated IND. Initial observations suggested that AXO-AAV-GM2 was generally well-tolerated and associated with improvement in bioactivity outcomes. In addition, data suggested attainment of normal neurodevelopmental milestones and improvement in myelination on brain MRI.

AXGT Axovant
$4.98

-0.08 (-1.58%)

06/06/19
JMPS
06/06/19
NO CHANGE
Target $28
JMPS
Outperform
Axovant price target raised to $28 after reverse split at JMP Securities
JMP Securities analyst Jason Butler raised his price target on Axovant shares to $28 from $8 to account for the stock's 1-for-8 reverse split and other share count changes. Additionally, he noted that he is enthused by the sustained improvements in OFF score that were reported at six months in the first cohort in the ongoing SUNRISE-PD Phase 2 trial in Parkinson's disease. Butler keeps an Outperform rating on Axovant shares, telling investors that today's updated results give him greater confidence in both the consistency and durability of benefits for AXO-Lenti-PD.
06/21/19
LEER
06/21/19
INITIATION
Target $18
LEER
Outperform
Axovant initiated with an Outperform at SVB Leerink
SVB Leerink initiated Axovant with an Outperform and $18 price target.
08/12/19
BARD
08/12/19
UPGRADE
Target $13
BARD
Outperform
Axovant upgraded to Outperform from Neutral at Baird
Baird analyst Brian Skorney upgraded Axovant Gene Therapies to Outperform from Neutral while lowering his price target for the shares to $13 from $16.
08/12/19
BARD
08/12/19
UPGRADE
Target $13
BARD
Outperform
Axovant upgraded to Outperform at Baird
As reported previously, Baird analyst Brian Skorney upgraded Axovant to Outperform from Neutral. The analyst cited excitement over the upcoming release of its gene-therapy data. He believes success in anyone of its three ongoing gene therapy programs would represent significant upside to today's value. Skorney lowered his price target to $13 from $16 on Axovant shares.

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