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CRL

Charles River

$158.00

1.07 (0.68%)

, TAK

Takeda Pharmaceutical

$19.92

0.13 (0.66%)

08:39
01/13/20
01/13
08:39
01/13/20
08:39

Charles River, Takeda Pharmaceutical announce drug discovery collaboration

Charles River (CRL) announced a multi-year drug discovery collaboration with Takeda Pharmaceutical (TAK). Together, Charles River and Takeda will launch multiple integrated programs across Takeda's four core therapeutic areas-oncology, gastroenterology, neuroscience, and rare disease-with the ultimate goal of delivering preclinical candidates that Takeda can advance into clinical development. The alliance combines Charles River's integrated drug discovery expertise and deep scientific bench with Takeda's investments in human data and translation to deliver medicines for patients aligned with Takeda's therapeutic strategies in oncology, gastrointestinal disease, neuroscience and rare disease. Charles River will leverage its end-to-end drug discovery and safety assessment platform to explore potential therapeutic approaches and progress these programs towards candidate status. Takeda will then have the option to advance the preclinical candidates through their clinical development pipeline. Under the terms of the agreement, Takeda will pay Charles River a one-time, upfront fee to establish the collaboration. Charles River will be eligible to receive development payments with a potential value of over $50M per program in preclinical and clinical milestones for candidates that progress to registration. The agreement also includes additional potential commercial milestones of up to $120M plus royalties on launched products.

CRL

Charles River

$158.00

1.07 (0.68%)

TAK

Takeda Pharmaceutical

$19.92

0.13 (0.66%)

  • 13

    Jan

CRL Charles River
$158.00

1.07 (0.68%)

01/06/20
SBSH
01/06/20
INITIATION
Target $185
SBSH
Buy
Charles River initiated with a Buy at Citi
Citi analyst Patrick Donnelly initiated coverage of Charles River with a Buy rating and $185 price target.
01/07/20
WELS
01/07/20
INITIATION
Target $180
WELS
Overweight
Charles River initiated with an Overweight at Wells Fargo
Wells Fargo analyst Dan Leonard initiated coverage of Charles River with an Overweight rating and $180 price target.
01/07/20
WELS
01/07/20
INITIATION
WELS
Wells Fargo initiates Life Science Tools, Services, Diagnostics Sector
Wells Fargo analyst Dan Leonard initiated coverage of the Life Science Tools, Services, and Diagnostics Sector in a research note titled "Tools, Services Have Evolved to Better Place but Stay Selective." Leonard said the sectors have "greater secular growth than 5+ years ago, with more exposure to Biopharma and China, and less cyclicality." While the analyst noted the industry has changed for the better, he advocated for being selective, citing elevated relative valuations due to the market recognizing these positives, and decelerating growth. The analyst initiated Agilent (A), Avantor (AVTR), Bio-Rad (BIO), Bruker (BRKR), Danaher (DHR), and Charles River (CRL) with Overweight ratings, noting they were all volatile, and initiated Iqvia (IQV) and LabCorp (LH) with Overweight ratings. The analyst initiated Quest Diagnostics (DGX) and Illumina (ILMN) with Underweight ratings, noting they were both volatile, and also initiated Waters (WAT) with an Underweight rating.
01/10/20
GSCO
01/10/20
UPGRADE
Target $179
GSCO
Buy
Charles River upgraded to Buy from Neutral at Goldman Sachs
Goldman Sachs analyst Robert Jones upgraded Charles River to Buy from Neutral with a price target of $179, up from $143. The analyst considers the outsourced R&D industry's trajectory to be intact into 2020 across preclinical and clinical phases of drug development. 2020 is set to be a strong biologics/small molecule launch year, which is a tailwind to Charles River's MS segment, Jones tells investors in a research note. He expects more consistency in results and sees an attractive entry point at current share levels.
TAK Takeda Pharmaceutical
$19.92

0.13 (0.66%)

09/05/19
HCWC
09/05/19
NO CHANGE
HCWC
Buy
H.C. Wainwright says KemPharm may have picked 'best possible' partner in GPC
After KemPharm (KMPH) announced a deal with private equity firm Gurnet Point Capital, H.C. Wainwright analyst Oren Livnat noted that investors reacted negatively to the deal, which he thinks is likely due to the relatively small $10M up-front and the partner being an unknown rather than an obvious ADHD player such as Takeda's (TAK) Shire. However, he thinks the Street is "entirely missing" that GPC "may actually be the best possible partner" given that it previously acquired CNS-focused Corium International and recently put new leadership in place almost entirely made up of recent Shire senior management. Livnat also believes that "deep-pocketed, private" GPC may be more willing than any other player, including Takeda, to provide the needed commercial support to make KP415 a success, he tells investors. He maintains a $3 price target and Buy rating on KemPharm shares.
09/24/19
JEFF
09/24/19
INITIATION
JEFF
Buy
Takeda Pharmaceutical initiated with a Buy at Jefferies
Jefferies analyst Stephen Barker started Takeda Pharmaceutical with a Buy rating and 6,000 yen price target.
11/01/19
COWN
11/01/19
INITIATION
Target $19.5
COWN
Market Perform
Takeda Pharmaceutical initiated with a Market Perform at Cowen
Cowen analyst Ken Cacciatore initiated coverage of Takeda Pharmaceutical with a Market Perform rating and $19.50 price target citing competitive pressures.
11/19/19
NEED
11/19/19
INITIATION
Target $40
NEED
Buy
Phathom Pharmaceuticals initiated with a Buy at Needham
Needham analyst Alan Carr initiated coverage of Phathom Pharmaceuticals (PHAT) with a Buy rating and $40 price target. The analyst is positive on the company's development of vonoprazan, a "novel oral potassium-competitive acid blocker for the treatment of Erosive Esophagitis and H. pylori infection", noting that its 2015 launch by Takeda (TAK) in Japan has demonstrated benefits over standard of care proton pump inhibitors in both indications. Having licensed the rights from Takeda, the analyst adds that the company's initiated Phase 3 trials in Erosive Esophagitis and H. pylori infection for registration in the U.S., Canada, and Europe, projecting a U.S. launch in 2022 and and U.S. peak sales of $1.9B-$2.0B in 2032.

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