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EDIT

Editas Medicine

$30.67

0.01 (0.03%)

09:10
01/13/20
01/13
09:10
01/13/20
09:10

Editas Medicine provides update on progress at JPMorgan Healthcare Conference

In a presentation to investors on Wednesday, January 15, 2020, at 10:30 a.m. PST at the 38th Annual J.P. Morgan Healthcare Conference, Editas Medicine President and CEO Cynthia Collins will discuss the Company's progress on developing in vivo and engineered cell medicines and building the leading genomic medicine company. In her remarks, Ms. Collins will discuss several components of the Company's progress and detail timelines, including plans to: Dose the first patient in the Brilliance clinical trial of EDIT-101 for the treatment of Leber congenital amaurosis 10 in the first quarter of 2020 and complete dosing the adult low- and mid-dose cohorts by the end of the year; File an Investigational New Drug application for EDIT-301 for the treatment of sickle cell disease by the end of 2020; Initiate IND-enabling studies for engineered natural killer cell medicine for the treatment of solid tumors; Advance alpha-beta T cell medicines in partnership with Bristol-Myers Squibb Company; Establish in vivo preclinical proof-of-concept for an engineered iPSC-derived NK cell medicine; and Establish in vivo preclinical proof-of-concept for a neurological indication. In addition to sharing details on the Company's progress and timelines, Ms. Collins will also discuss recent achievements and outlook for 2020:Progress in In Vivo CRISPR Medicines EDIT-101 is on track to be the first in vivo CRISPR-based genome editing medicine with first patient dosing expected in the first quarter of 2020. EDIT-102 development candidate declared for the treatment of Usher syndrome 2A. Declare a development candidate for Autosomal Dominant Retinitis Pigmentosa Type 4 in 2020. Plans to establish in vivo preclinical proof-of-concept for a neurological indication in 2020 from collaboration with Asklepios BioPharmaceutical. File an IND for EDIT-301 for the treatment of sickle cell disease by the end of 2020. Progress on the Company's collaboration with Bristol-Myers Squibb to advance alpha-beta T cell medicines for the treatment of both solid and liquid tumors. Declare a development candidate and initiate IND-enabling activities this year for a gene edited healthy donor NK cell medicine. Progress towards establishing in vivo preclinical proof-of-concept for an engineered iNK cell medicine using technology from BlueRock Therapeutics. Advanced and strengthened pipeline through multiple collaborations and licensing agreements, including Bristol-Myers Squibb, BlueRock Therapeutics LP, AskBio, MaxCyte, Inc., and Sandhill Therapeutics, Inc. Strengthened the Company's executive team with hiring of a permanent Chief Executive Officer, Chief Financial Officer, Chief Medical Officer, and Senior Vice President, Operations.

  • 13

    Jan

EDIT Editas Medicine
$30.67

0.01 (0.03%)

02/07/19
BTIG
02/07/19
INITIATION
BTIG
Buy
Editas Medicine initiated with a Buy at BTIG
BTIG analyst Amanda Murphy initiated Editas Medicine with a Buy rating and $30 price target. Murphy sees Editas having the broadest CRISPR toolbox, noting that "with its IP portfolio, Editas can target ten times as many sites in the genome relative to wild-type spCas9 and roughly 95% of the human genome in total."
04/11/19
EVER
04/11/19
INITIATION
Target $34
EVER
Outperform
Editas Medicine initiated with an Outperform at Evercore ISI
Evercore ISI analyst Ravi Mehrotra initiated Editas Medicine (EDIT) with an Outperform rating and a price targets of $34. The analyst cites the company's "strong clinical positioning of lead program EDIT-101", saying that if its efficacy is demonstrated in LCA-10 and proven durable, it will likely have "significant uptake over Sepofarsen, which requires chronic dosing." Mehrotra adds that Editas Medicine's partnership with Allergan (AGN) "adds reinforcement".
04/22/19
BTIG
04/22/19
NO CHANGE
BTIG
Buy
BTIG raises price targets on Editas Medicine, CRISPR Therapeutics
BTIG analyst Amanda Murphy raised her price target on Buy-rated Editas Medicine (EDIT) to $33 from $30 and CRISPR Therapeutics (CRSP) to $49 from $43 as part of her first installment of a broader research note analyzing hiring trends in the gene therapy space. The analyst notes that the latter is "aggressively adding process development/CMC/Tech capabilities in cell therapy, including late stage process development resources", which may suggest that the company is "farther along" in the development of CTX110. Murphy also observes that Editas Medicine appears to be "shifting focus to engineered stem cell therapy while still investing in allo CAR-T and potentially new in vivo indications and delivery vectors."
12/03/19
RAJA
12/03/19
DOWNGRADE
RAJA
Market Perform
Audentes downgraded to Market Perform from Outperform at Raymond James
Raymond James analyst Steven Seedhouse downgraded Audentes Therapeutics (BOLD) to Market Perform from Outperform after the company agreed to be aquired by Astellas Pharma (ALPMY) for $60 per share. The analyst, who views the deal as "another bullish domino for genetic medicine," expects shares of Editas Medicine (EDIT), Intellia Therapeutics (NTLA) and Crispr Therapeutics (CRSP) to "benefit from the optics."

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