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IOVA

Iovance Biotherapeutics

$24.34

0.345 (1.44%)

08:01
01/15/20
01/15
08:01
01/15/20
08:01

Iovance Biotherapeutics completes patient dosing in cohort 4 of C-144-01 study

Iovance Biotherapeutics announced that the company has completed dosing the last patient in the registration-enabling Cohort 4 of the C-144-01 study of lifileucel in the treatment of patients with advanced melanoma. Cohort 4 has the primary endpoint of objective response rate to be read out by an Independent Review Committee.Iovance Tumor Infiltrating Lymphocytes for melanoma, lifileucel, is an investigational, patient-derived cell therapy that involves a 22-day manufacturing process at a centralized facility. Cohort 4 in the C-144-01 study includes post-PD-1 patients with Stage IIIC/IV unresectable melanoma who also have received BRAF/MEK therapy if clinically indicated. Lifileucel has been granted Regenerative Medicine Advanced Therapy, Fast Track and Orphan Drug designations in advanced melanoma.

IOVA Iovance Biotherapeutics
$24.34

0.345 (1.44%)

11/10/19
PIPR
11/10/19
NO CHANGE
PIPR
Piper Jaffray reiterates Overweight on Iovance after SITC update
Piper Jaffray analyst Joseph Catanzaro reiterated an Overweight rating and $30 price target on Iovance following the company's update for cohort 2 of melanoma's lifileucel study at SITC. The analyst said that even a worst case scenario on the data "points to an eventual very favorable mDOR for cohort 2." Catanzaro reiterated that he believes "this has implications around commercial adoption and peak penetration if replicated in cohort 4," which is projected to complete enrollment in the Q1 of 2020, with a regulatory filing in late 2020.
11/21/19
WELS
11/21/19
NO CHANGE
WELS
Outperform
Iovance financing concerns misplaced, says Well Fargo
Wells Fargo analyst Jim Birchenough said he believes weakness in shares of Iovance Biotherapeutics may be related to concern regarding the potential for a dilutive financing following the company's release of "positive" data from the phase 2 study of lifileucel in melanoma. However, he has spoken with management and they have confirmed adequate cash and said they do not need additional capital at the current time, Birchenough said. He believes any financing concerns are misplaced and would be a buyer on the weakness, added the analyst, who has an Outperform rating on Iovance shares.
12/18/19
JMPS
12/18/19
INITIATION
Target $38
JMPS
Outperform
Iovance Biotherapeutics initiated with an Outperform at JMP Securities
JMP Securities analyst Reni Benjamin initiated coverage of Iovance Biotherapeutics with an Outperform rating and $38 price target. The analyst cites the company's multiple ongoing pivotal trials in melanoma and cervical cancer, noting that the clinical data from its earlier trials demonstrated "impressive efficacy." Benjamin adds that Iovance is also conducting tumor infiltrating lymphocytes, or TIL, trials in head/ neck cancer and non-small cell lung cancer as well as other indications.
01/14/20
PIPR
01/14/20
NO CHANGE
Target $30
PIPR
Overweight
Iovance Biotherapeutics quietly provided 'positive' update, says Piper Sandler
Piper Sandler analyst Joseph Catanzaro says Iovance Biotherapeutics quietly provided a positive update for cohort 2 of melanoma, noting that at a median follow-up of 15.5 months, the median duration of response has still not been reached. With regards to 2020 data, Catanzaro tells investors in a research note that the company continues to guide toward top-line registrational melanoma and cervical cancer data in 2H20. Outside of this, he says the company noted that in order to see data from COM-202, it would want to have at least five patients in a cohort and one confirmed response. The analyst made no change to his Overweight rating and $30 price target.

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