Breaking News Instant updates and real-time market news.

EXEL

Exelixis

$17.88 /

+0.145 (+0.82%)

, TAK

Takeda Pharmaceutical

$19.76 /

+0.025 (+0.13%)

05:29
01/29/20
01/29
05:29
01/29/20
05:29

Exelixis says Takeda Pharmaceutical files NDA in Japan for CABOMETYX

Exelixis (EXEL) announced that Takeda Pharmaceutical (TAK), its partner responsible for the clinical development and commercialization of CABOMETYX in Japan, has applied to the Japanese Ministry of Health, Labor and Welfare, or MHLW, for Manufacturing and Marketing Approval of cabozantinib as a treatment for patients with unresectable hepatocellular carcinoma, or HCC, that had progressed after prior systemic therapy. Takeda's application is based on the results of two clinical trials in patients with advanced HCC who had received prior systemic therapy: CELESTIAL, a global, randomized, placebo-controlled, double-blind phase 3 clinical trial, and Cabozantinib-2003, a phase 2 clinical trial conducted in Japan. "We are excited about the progress our partner Takeda has made on advancing cabozantinib toward regulatory approval in Japan for patients with advanced liver cancer," said Michael Morrissey, Ph.D., President and CEO of Exelixis. "This regulatory filing is an important milestone for patients in Japan who currently have limited treatment options after they have progressed following systemic therapy. We look forward to our continued collaboration as Takeda works to bring cabozantinib to patients in need of new therapies." Per the terms of Exelixis and Takeda's collaboration and license agreement, Exelixis is eligible to receive a $10M milestone payment from Takeda as a result of this latest submission for HCC, which is anticipated to be received in the first quarter of 2020. In April 2019, Takeda applied for approval to manufacture and sell cabozantinib as a treatment for unresectable and metastatic renal cell carcinoma, or RCC, in Japan. Following the milestone associated with this HCC regulatory filing, Exelixis will be eligible to receive further development, regulatory and first-sale milestone payments of up to $76M from Takeda related both to previously treated and previously untreated RCC and previously treated HCC. Exelixis continues to be eligible to receive additional development, regulatory and first-sale milestones for potential future cabozantinib indications, and is also eligible for sales revenue milestones and royalties on net sales of cabozantinib in Japan. Takeda fully funds cabozantinib development activities that are exclusively for the benefit of Japan and is responsible for 20% of the costs associated with global cabozantinib clinical trials, providing the company opts into those trials.

EXEL

Exelixis

$17.88 /

+0.145 (+0.82%)

TAK

Takeda Pharmaceutical

$19.76 /

+0.025 (+0.13%)

  • 04

    Feb

  • 13

    Feb

  • 13

    Mar

EXEL Exelixis
$17.88 /

+0.145 (+0.82%)

01/13/20 SunTrust
Exelixis initiated with a Buy at SunTrust
01/12/20 Piper Sandler
Exelixis shares to trade lower on guidance, says Piper Sandler
01/02/20 Guggenheim
Incyte downgraded to Neutral after strong 2019 at Guggenheim
11/13/19 BofA
Exelixis initiated with a Buy at BofA/Merrill
TAK Takeda Pharmaceutical
$19.76 /

+0.025 (+0.13%)

11/19/19 Needham
Phathom Pharmaceuticals initiated with a Buy at Needham
11/01/19 Cowen
Takeda Pharmaceutical initiated with a Market Perform at Cowen
09/24/19 Jefferies
Takeda Pharmaceutical initiated with a Buy at Jefferies
09/05/19 H.C. Wainwright
H.C. Wainwright says KemPharm may have picked 'best possible' partner in GPC

TODAY'S FREE FLY STORIES

Hot Stocks
Urban Outfitters suspends hiring, eliminates bonuses for FY21 » 09:17
03/31/20
03/31
09:17
03/31/20
09:17
URBN

Urban Outfitters

$14.56 /

-0.04 (-0.27%)

The company is taking…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
News Corp to sell NAM business for up to $235M in cash considerations » 09:17
03/31/20
03/31
09:17
03/31/20
09:17
NWS

News Corp

$8.86 /

+0.43 (+5.10%)

, NWSA

News Corp.

$8.81 /

+0.29 (+3.40%)

News Corp announced that…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Urban Outfitters says stores will remain closed, furloughs number of employees » 09:16
03/31/20
03/31
09:16
03/31/20
09:16
URBN

Urban Outfitters

$14.56 /

-0.04 (-0.27%)

Urban Outfitters…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Recommendations
PG&E price target lowered to $10 from $16 at Morgan Stanley » 09:15
03/31/20
03/31
09:15
03/31/20
09:15
PCG

PG&E

$9.64 /

+ (+0.00%)

Morgan Stanley analyst…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Conference/Events
Realty Income participates in a conference call with Stifel » 09:15
03/31/20
03/31
09:15
03/31/20
09:15
O

Realty Income

$52.88 /

-3.88 (-6.84%)

Conference call with…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

General news
U.S. Case Shiller home price index dipped -0.04% in January to 218.6 for the 20-City » 09:15
03/31/20
03/31
09:15
03/31/20
09:15

U.S. Case Shiller home…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

Hot Stocks
Eastman Chemical partners with THEC to produce 10,000 protective face shields » 09:14
03/31/20
03/31
09:14
03/31/20
09:14
EMN

Eastman Chemical

$47.53 /

+1.15 (+2.48%)

Eastman recently…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Broadcom says Stingray adapter powers Baidu Cloud » 09:13
03/31/20
03/31
09:13
03/31/20
09:13
BIDU

Baidu

$98.95 /

+1.31 (+1.34%)

, AVGO

Broadcom

$239.61 /

+8.92 (+3.87%)

Broadcom (AVGO) announced…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Ford further postpones North America production restart to protect workforce » 09:12
03/31/20
03/31
09:12
03/31/20
09:12
GE

General Electric

$7.88 /

+0.25 (+3.28%)

, F

Ford

$5.04 /

-0.155 (-2.99%)

Ford (F) is delaying the…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Marlin Business expects Q1, FY20 to be 'adversely impacted' by COVID-19 » 09:12
03/31/20
03/31
09:12
03/31/20
09:12
MRLN

Marlin Business

$11.08 /

+1.3 (+13.29%)

The company said,…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

Downgrade
Baozun downgraded to Neutral on slowing near-term growth at BofA » 09:11
03/31/20
03/31
09:11
03/31/20
09:11
BZUN

Baozun

$26.51 /

-0.55 (-2.03%)

BofA analyst Joyce Ju…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Marlin Business limits origination activities in certain high-risk industries » 09:11
03/31/20
03/31
09:11
03/31/20
09:11
MRLN

Marlin Business

$11.08 /

+1.3 (+13.29%)

The company said,…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

Downgrade
Daicel downgraded to Underperform from Hold at Jefferies » 09:10
03/31/20
03/31
09:10
03/31/20
09:10
DACHF

Daicel

$0.00 /

+ (+0.00%)

Jefferies analyst…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Marlin Business implements business continuity plan » 09:10
03/31/20
03/31
09:10
03/31/20
09:10
MRLN

Marlin Business

$11.08 /

+1.3 (+13.29%)

Throughout the week of…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

Hot Stocks
Marlin Business announces termination of CMLA agreement » 09:10
03/31/20
03/31
09:10
03/31/20
09:10
MRLN

Marlin Business

$11.08 /

+1.3 (+13.29%)

Marlin Business Services…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

Conference/Events
Euronet participates in a conference call with Northland » 09:09
03/31/20
03/31
09:09
03/31/20
09:09
EEFT

Euronet

$89.92 /

-1.51 (-1.65%)

Financial Services…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

On The Fly
Fly Intel: Pre-market Movers » 09:09
03/31/20
03/31
09:09
03/31/20
09:09
CCO

Clear Channel Outdoor

$0.52 /

-0.0398 (-7.11%)

, SQNS

Sequans

$5.50 /

-0.185 (-3.25%)

, NBL

Noble Energy

$5.30 /

-0.03 (-0.56%)

, PEI

Pennsylvania REIT

$0.89 /

-0.0302 (-3.28%)

, CAG

Conagra Brands

$28.35 /

+0.47 (+1.69%)

, RH

RH

$117.68 /

+6.09 (+5.46%)

, SNDL

Sundial Growers

$0.98 /

-0.072 (-6.86%)

, DLTR

Dollar Tree

$79.81 /

+2.8 (+3.64%)

, MTNB

Matinas BioPharma

$0.71 /

-0.0093 (-1.29%)

, CCL

Carnival

$12.80 /

-1.61 (-11.17%)

, TWLO

Twilio

$96.97 /

+0.34 (+0.35%)

Check out this morning's…

Open Full Text

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 02
    Apr
Recommendations
Expedia price target lowered to $79 from $100 at RBC Capital » 09:08
03/31/20
03/31
09:08
03/31/20
09:08
EXPE

Expedia

$56.46 /

-3.58 (-5.96%)

RBC Capital analyst Mark…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
OrthoPediatrics receives FDA 510(k) clearance, expanded indications for RESPONSE » 09:08
03/31/20
03/31
09:08
03/31/20
09:08
KIDS

OrthoPediatrics

$40.28 /

+4.08 (+11.27%)

OrthoPediatrics announced…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Fitbit announces launch of Fitbit Charge 4 » 09:08
03/31/20
03/31
09:08
03/31/20
09:08
FIT

Fitbit

$6.66 /

+0.205 (+3.18%)

Fitbit announced the…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Smart Global shareholders approve amendment authorizing approval of repurchases » 09:07
03/31/20
03/31
09:07
03/31/20
09:07
SGH

Smart Global

$23.98 /

+1.8 (+8.12%)

SMART Global Holdings…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Nabors Industries files definitive proxy statement for reverse stock split » 09:07
03/31/20
03/31
09:07
03/31/20
09:07
NBR

Nabors Industries

$0.37 /

-0.0555 (-12.90%)

Nabors Industries…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Conference/Events
Aerie Pharmaceuticals participates in a conference call with Stifel » 09:07
03/31/20
03/31
09:07
03/31/20
09:07
AERI

Aerie Pharmaceuticals

$13.39 /

+0.24 (+1.83%)

Conference call with…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Recommendations
LivePerson price target lowered to $35 from $47 at Craig-Hallum » 09:06
03/31/20
03/31
09:06
03/31/20
09:06
LPSN

LivePerson

$23.35 /

+0.69 (+3.05%)

Craig-Hallum analyst Jeff…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Downgrade
Siemens downgraded to Hold from Buy at Vertical Research » 09:06
03/31/20
03/31
09:06
03/31/20
09:06
SIEGY

Siemens

$0.00 /

+ (+0.00%)

Vertical Research analyst…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.