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TAK

Takeda Pharmaceutical

$19.66 /

+ (+0.00%)

09:42
02/14/20
02/14
09:42
02/14/20
09:42

Takeda says Phase 3 VISIBLE 2 trial met primary endpoint in week 52 patients

Takeda Pharmaceutical announced results from the phase 3 VISIBLE 2 clinical trial evaluating the efficacy and safety of an investigational subcutaneous formulation of the gut-selective biologic vedolizumab for use during maintenance therapy in adult patients with moderately to severely active Crohn's disease. The study evaluated patients who achieved clinical response at week 6 following two doses of open-label vedolizumab intravenous induction therapy at weeks 0 and 2.1 The results show that at week 52, significantly more patients on vedolizumab SC compared to placebo were in clinical remission, meeting the study's primary endpoint. These data were announced during an oral presentation at the 15th Congress of the European Crohn's and Colitis Organisation in Vienna, Austria. Results for the following secondary endpoints were also presented at the congress. The enhanced clinical response rate was 52.0% in patients receiving vedolizumab SC versus 44.8% in patients on placebo at week 52. The difference between the treatment groups was not statistically significant, and consequently statistical testing for the remaining secondary endpoints was not performed.

  • 13

    Mar

TAK Takeda Pharmaceutical
$19.66 /

+ (+0.00%)

02/12/20 Wells Fargo
Fate Therapeutics price target raised to $34 from $24 at Wells Fargo
11/19/19 Needham
Phathom Pharmaceuticals initiated with a Buy at Needham
11/01/19 Cowen
Takeda Pharmaceutical initiated with a Market Perform at Cowen
09/24/19 Jefferies
Takeda Pharmaceutical initiated with a Buy at Jefferies

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