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HRZN

Horizon Technology

$6.53 /

+0.51 (+8.47%)

08:27
03/25/20
03/25
08:27
03/25/20
08:27

Castle Creek Biosciences announces $75M investment to advance candidates

Castle Creek Biosciences announced that it has received a new investment of $75M to support the advancement of its clinical development pipeline. Castle Creek Biosciences is a portfolio company of Paragon Biosciences, which led the $55M equity investment from Fidelity Management & Research Company and Valor Equity Partners, along with a $20M venture loan from Horizon Technology Finance Corporation. Castle Creek Biosciences is leveraging its proprietary technology platform and commercial-scale manufacturing infrastructure to develop personalized gene therapies for rare diseases with high unmet needs. The company plans to use the funding to advance and expand its gene therapy pipeline, led by the Phase 3 clinical development of FCX-007, its gene therapy candidate for the treatment of RDEB. It will also use the funding to expand its current good manufacturing practices infrastructure located in the greater Philadelphia region. Clinical results from the ongoing Phase 1/2 clinical trial for FCX-007 continue to show positive trends in safety and wound healing in RDEB patients. Current data from this clinical trial were presented at the inaugural World Congress on Epidermolysis Bullosa held in London during January of 2020. FCX-007 was administered to 10 non-healing chronic wounds of which eight achieved complete wound closure 12 weeks post-administration vs. no wound closure in intra-patient, matched non-treated wound. FCX-007 continues to be well tolerated up to 52 weeks post administration.

HRZN Horizon Technology
$6.53 /

+0.51 (+8.47%)

03/04/20 Aegis
Horizon Technology upgraded to Buy from Hold at Aegis
02/28/20 Compass Point
Horizon Technology upgraded to Neutral from Sell at Compass Point
02/04/20
Fly Intel: Top five analyst initiations
02/04/20 B. Riley FBR
Horizon Technology initiated with a Neutral at B. Riley FBR

TODAY'S FREE FLY STORIES

Recommendations
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General news
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Hot Stocks
Zealand Pharma submits NDA to FDA for Dasiglucagon HypoPal Rescue Pen » 09:47
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Conference/Events
Cowen software/services analysts to hold an analyst/industry conference call » 09:46
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White Mountains-backed Kudu makes minority investment in Creation Investments » 09:46
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Recommendations
Northland cuts Intel target to $60 ahead of 'ugly' second half of year » 09:45
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General news
Consumer Confidence to be reported at 10:00 » 09:45
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Periodicals
Biohaven news could put company 'back in play,' Dealreporter says » 09:43
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+ (+0.00%)

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Recommendations
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$12.15 /

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  • 02
    Apr
Options
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Conference/Events
Morgan Stanley oil analysts to hold an analyst/industry conference call » 09:39
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Royal Caribbean trading resumes  09:39
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Royal Caribbean

$29.80 /

-4.71 (-13.65%)

 
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Recommendations
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LEGH

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$9.86 /

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B. Riley FBR analyst Alex…

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$8.25 /

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BRP Group Inc (Class A Stock) trading halted, volatility trading pause  09:38
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Recommendations
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$58.16 /

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Periodicals
Axalta Coating came 'very close' to reaching deal before virus crisis, CNBC says » 09:36
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Axalta Coating

$18.07 /

+0.365 (+2.06%)

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  • 02
    Apr
Recommendations
Farmer Bros. price target lowered to $8 from $12 at B. Riley FBR » 09:34
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FARM

Farmer Bros.

$7.03 /

-0.03 (-0.42%)

B. Riley FBR analyst Kara…

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Hot Stocks
Royal Caribbean trading halted, volatility trading pause  09:34
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Conference/Events
Himax participates in a conference call with Lake Street » 09:33
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HIMX

Himax

$2.66 /

+0.06 (+2.31%)

Conference call with CFO…

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