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ORIC

Oric Pharmaceuticals

$26.10 /

+0.35 (+1.36%)

16:34
04/27/20
04/27
16:34
04/27/20
16:34

ORIC Pharmaceuticals presents preclinical data on CD73 inhibitor

ORIC Pharmaceuticals presented research that led to the discovery of potent and orally bioavailable small molecule inhibitors of CD73 at the 2020 American Association for Cancer Research Virtual Annual Meeting I. The preclinical data on ORIC's CD73 program were presented in the "Advances in Cancer Drug Design and Discovery" session in an oral presentation titled "Orally Available Small Molecule CD73 Inhibitor Reverses Immunosuppression Through Blocking of Adenosine Production." Many cancers usurp the anti-inflammatory adenosine pathway to avoid detection by the immune system, thereby reducing the effectiveness of certain chemotherapy- and immunotherapy-based treatments. Accumulation of adenosine in the tumor microenvironment is implicated in local immune suppression that leads to tumor growth. CD73 is an enzyme that controls the rate at which extracellular adenosine is produced and its overexpression is associated with poor prognosis in several cancers, including triple negative breast cancer, non-small cell lung cancer, melanoma and prostate cancer, among others. Therefore, reducing the level of adenosine via inhibition of CD73 has become a potential strategy for cancer treatment. ORIC's small molecule inhibitor of CD73 demonstrated more potent adenosine inhibition compared to an antibody approach in preclinical studies. Further studies showed CD73 inhibition impacted T cell proliferation and cytokine production in the context of adenosine-mediated immunosuppression. ORIC's research program led to the discovery of clinical candidate ORIC-533, an orally bioavailable small molecule inhibitor of CD73, which in preclinical studies demonstrated significant anti-tumor single agent efficacy when dosed once a day, with corresponding reduction of adenosine levels in the tumor microenvironment. ORIC expects to file an IND for ORIC-533 in the first half of 2021.

TODAY'S FREE FLY STORIES

Recommendations
Owens & Minor earnings power not reflected in shares, says Baird » 06:43
04/13/21
04/13
06:43
04/13/21
06:43
OMI

Owens & Minor

$36.70 /

+0.03 (+0.08%)

Baird analyst Eric…

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OMI Owens & Minor
$36.70 /

+0.03 (+0.08%)

OMI Owens & Minor
$36.70 /

+0.03 (+0.08%)

03/26/21 Baird
Owens & Minor price target raised to $50 from $45 at Baird
02/25/21 Barclays
Owens & Minor price target raised to $33 from $23 at Barclays
12/17/20
Fly Intel: Top five analyst upgrades
12/17/20 UBS
Owens & Minor upgraded to Buy from Neutral at UBS
OMI Owens & Minor
$36.70 /

+0.03 (+0.08%)

  • 02
    Oct
OMI Owens & Minor
$36.70 /

+0.03 (+0.08%)

OMI Owens & Minor
$36.70 /

+0.03 (+0.08%)

Initiation
Finch Therapeutics initiated with an Outperform at Evercore ISI » 06:42
04/13/21
04/13
06:42
04/13/21
06:42
FNCH

Finch Therapeutics

$17.00 /

-0.26 (-1.51%)

Evercore ISI analyst Josh…

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FNCH Finch Therapeutics
$17.00 /

-0.26 (-1.51%)

06:07 Today BofA
Finch Therapeutics initiated with a Buy at BofA
  • 19
    Mar
FNCH Finch Therapeutics
$17.00 /

-0.26 (-1.51%)

Recommendations
Rockwell Automation named 'Catalyst Call: Sell Idea' at Deutsche Bank » 06:42
04/13/21
04/13
06:42
04/13/21
06:42
ROK

Rockwell Automation

$264.99 /

+0.44 (+0.17%)

Deutsche Bank analyst…

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ROK Rockwell Automation
$264.99 /

+0.44 (+0.17%)

ROK Rockwell Automation
$264.99 /

+0.44 (+0.17%)

04/06/21 Barclays
Rockwell Automation price target raised to $269 from $265 at Barclays
03/23/21 Morgan Stanley
Rockwell Automation price target raised to $300 from $291 at Morgan Stanley
03/19/21 Longbow
Rockwell Automation checks suggest upside to consensus, says Longbow
02/09/21 Stifel
Autodesk price target raised to $342 from $285 at Stifel
ROK Rockwell Automation
$264.99 /

+0.44 (+0.17%)

Initiation
First Guaranty Bancshares initiated with a Neutral at DA Davidson » 06:40
04/13/21
04/13
06:40
04/13/21
06:40
FGBI

First Guaranty Bancshares

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DA Davidson analyst Kevin…

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12/21/20 Janney Montgomery Scott
First Guaranty Bancshares initiated with a Buy at Janney Montgomery Scott
Recommendations
Vertiv Holdings named 'Catalyst Call: Buy Idea" at Deutsche Bank » 06:40
04/13/21
04/13
06:40
04/13/21
06:40
VRT

Vertiv Holdings

$21.60 /

+0.165 (+0.77%)

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VRT Vertiv Holdings
$21.60 /

+0.165 (+0.77%)

VRT Vertiv Holdings
$21.60 /

+0.165 (+0.77%)

04/08/21 JPMorgan
Vertiv Holdings initiated with an Overweight at JPMorgan
02/25/21 Deutsche Bank
Vertiv Holdings price target raised to $24 from $21 at Deutsche Bank
02/08/21 Cowen
Vertiv Holdings remains a top pick for 2021 at Cowen
12/23/20 Citi
Vertiv warrant redemption removes overhang, says Citi
VRT Vertiv Holdings
$21.60 /

+0.165 (+0.77%)

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Hot Stocks
Cardlytics to acquire Bridg for $350M in cash » 06:40
04/13/21
04/13
06:40
04/13/21
06:40
CDLX

Cardlytics

$111.96 /

+0.81 (+0.73%)

Cardlytics announced its…

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CDLX Cardlytics
$111.96 /

+0.81 (+0.73%)

CDLX Cardlytics
$111.96 /

+0.81 (+0.73%)

03/16/21 JPMorgan
Cardlytics price target raised to $130 from $110 at JPMorgan
03/05/21 BofA
Cardlytics upgraded to Neutral from Underperform at BofA
03/05/21 BofA
Cardlytics upgraded to Neutral from Underperform at BofA
03/02/21 Truist
Cardlytics price target raised to $150 from $90 at Truist
CDLX Cardlytics
$111.96 /

+0.81 (+0.73%)

  • 03
    Mar
Syndicate
Essential Properties Realty Trust 7.15M share Spot Secondary priced at $23.50 » 06:39
04/13/21
04/13
06:39
04/13/21
06:39
EPRT

Essential Properties Realty Trust

$24.40 /

+0.1 (+0.41%)

The deal size was…

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EPRT Essential Properties Realty Trust
$24.40 /

+0.1 (+0.41%)

EPRT Essential Properties Realty Trust
$24.40 /

+0.1 (+0.41%)

04/07/21 BofA
Essential Properties Realty Trust upgraded to Buy from Underperform at BofA
04/07/21 BofA
Essential Properties Realty Trust upgraded to Buy from Underperform at BofA
03/16/21 Truist
Essential Properties Realty Trust price target raised to $26 from $23 at Truist
03/04/21 Mizuho
Essential Properties Realty Trust price target raised to $26 from $22 at Mizuho
EPRT Essential Properties Realty Trust
$24.40 /

+0.1 (+0.41%)

  • 13
    Apr
  • 18
    Sep
Initiation
Aker Carbon Capture initiated with an Equal Weight at Morgan Stanley » 06:39
04/13/21
04/13
06:39
04/13/21
06:39
AKCCF

Aker Carbon Capture

$2.00 /

+ (+0.00%)

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Recommendations
Honeywell named 'Catalyst Call: Buy Idea" at Deutsche Bank » 06:38
04/13/21
04/13
06:38
04/13/21
06:38
HON

Honeywell

$228.57 /

+1.335 (+0.59%)

Deutsche Bank analyst…

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HON Honeywell
$228.57 /

+1.335 (+0.59%)

HON Honeywell
$228.57 /

+1.335 (+0.59%)

04/09/21 JPMorgan
JPMorgan's Tusa raises target on top pick Honeywell to $250 from $200
04/08/21 Deutsche Bank
Deutsche Bank upgrades Honeywell on 'rare buying opportunity'
04/08/21 Deutsche Bank
Honeywell upgraded to Buy from Hold at Deutsche Bank
04/06/21 Barclays
Honeywell price target raised to $230 from $225 at Barclays
HON Honeywell
$228.57 /

+1.335 (+0.59%)

HON Honeywell
$228.57 /

+1.335 (+0.59%)

HON Honeywell
$228.57 /

+1.335 (+0.59%)

Downgrade
Cadence Bancorp downgraded to Market Perform from Outperform at Raymond James » 06:37
04/13/21
04/13
06:37
04/13/21
06:37
CADE

Cadence Bancorp

$22.41 /

+0.92 (+4.28%)

Raymond James analyst…

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CADE Cadence Bancorp
$22.41 /

+0.92 (+4.28%)

CADE Cadence Bancorp
$22.41 /

+0.92 (+4.28%)

06:10 Today RBC Capital
Cadence Bancorp downgraded to Sector Perform from Outperform at RBC Capital
04/12/21 RBC Capital
Cadence Bancorp downgraded to Sector Perform from Outperform at RBC Capital
02/23/21 Stephens
Stephens raises Regions price target to $23, sees possible deal for Cadence
08/18/20 Keefe Bruyette
Cadence Bancorp upgraded to Outperform from Market Perform at Keefe Bruyette
CADE Cadence Bancorp
$22.41 /

+0.92 (+4.28%)

CADE Cadence Bancorp
$22.41 /

+0.92 (+4.28%)

Recommendations
Agco named 'Catalyst Call: Buy Idea' at Deutsche Bank » 06:37
04/13/21
04/13
06:37
04/13/21
06:37
AGCO

Agco

$148.83 /

+1.33 (+0.90%)

Deutsche Bank analyst…

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AGCO Agco
$148.83 /

+1.33 (+0.90%)

AGCO Agco
$148.83 /

+1.33 (+0.90%)

03/16/21 Citi
Agco price target raised to $165 from $140 at Citi
03/05/21 Credit Suisse
Agco price target raised to $142 from $131 at Credit Suisse
03/04/21 BMO Capital
Agco price target raised to $200 from $155 at BMO Capital
03/04/21 Deutsche Bank
Agco price target raised to $145 from $141 at Deutsche Bank
AGCO Agco
$148.83 /

+1.33 (+0.90%)

Hot Stocks
Cerevel Therapeutics announces $125M financing transaction for tavapadon » 06:36
04/13/21
04/13
06:36
04/13/21
06:36
CERE

Cerevel Therapeutics

$13.62 /

+0.58 (+4.45%)

Cerevel Therapeutics…

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CERE Cerevel Therapeutics
$13.62 /

+0.58 (+4.45%)

CERE Cerevel Therapeutics
$13.62 /

+0.58 (+4.45%)

12/10/20 Goldman Sachs
Cerevel Therapeutics initiated with a Buy at Goldman Sachs
11/23/20 Jefferies
Cerevel Therapeutics initiated with a Buy at Jefferies
11/09/20
Fly Intel: Top five analyst initiations
11/09/20 Stifel
Cerevel Therapeutics initiated with a Buy at Stifel
CERE Cerevel Therapeutics
$13.62 /

+0.58 (+4.45%)

CERE Cerevel Therapeutics
$13.62 /

+0.58 (+4.45%)

Hot Stocks
Sierra Metals reports high-grade oxide polymetallic ore detection » 06:35
04/13/21
04/13
06:35
04/13/21
06:35
SMTS

Sierra Metals

$2.99 /

-0.11 (-3.55%)

Sierra Metals announces…

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SMTS Sierra Metals
$2.99 /

-0.11 (-3.55%)

SMTS Sierra Metals
$2.99 /

-0.11 (-3.55%)

12/16/20 CIBC
Sierra Metals price target raised to C$4.80 from C$3.50 at CIBC
11/10/20 CIBC
Sierra Metals price target raised to C$3.50 from C$3.30 at CIBC
09/17/20 CIBC
Sierra Metals price target raised to C$3.30 from C$2.60 at CIBC
09/11/20 CIBC
CIBC starts Sierra Metals at Outperformer ahead of cash flow pickup
Initiation
Coinbase initiated with a Buy at MoffettNathanson » 06:35
04/13/21
04/13
06:35
04/13/21
06:35
COIN

Coinbase

/

+

MoffettNathanson analyst…

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COIN Coinbase
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+

COIN Coinbase
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04/07/21 JMP Securities
Coinbase report shows 'substantial business momentum,' says JMP Securities
03/03/21
Fly Intel: Top five analyst initiations
03/03/21 DA Davidson
Coinbase initiated with a Buy at DA Davidson
COIN Coinbase
/

+

COIN Coinbase
/

+

COIN Coinbase
/

+

Recommendations
3M named 'Catalyst Call: Sell Idea' at Deutsche Bank » 06:35
04/13/21
04/13
06:35
04/13/21
06:35
MMM

3M

$197.73 /

-0.28 (-0.14%)

Deutsche Bank analyst…

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MMM 3M
$197.73 /

-0.28 (-0.14%)

MMM 3M
$197.73 /

-0.28 (-0.14%)

04/06/21 Barclays
3M price target raised to $180 from $163 at Barclays
03/23/21 Credit Suisse
3M price target raised to $202 from $197 at Credit Suisse
02/03/21
Fly Intel: Top five analyst upgrades
02/03/21 Argus
3M upgraded to Buy from Hold at Argus
MMM 3M
$197.73 /

-0.28 (-0.14%)

MMM 3M
$197.73 /

-0.28 (-0.14%)

MMM 3M
$197.73 /

-0.28 (-0.14%)

MMM 3M
$197.73 /

-0.28 (-0.14%)

Periodicals
Credit Suisse cuts employee bonuses following $4.7B Archegos loss, FT reports » 06:34
04/13/21
04/13
06:34
04/13/21
06:34
CS

Credit Suisse

$10.72 /

+0.08 (+0.75%)

Credit Suisse has cut…

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CS Credit Suisse
$10.72 /

+0.08 (+0.75%)

CS Credit Suisse
$10.72 /

+0.08 (+0.75%)

04/12/21 UBS
Credit Suisse price target lowered to CHF 10.20 from CHF 12.10 at UBS
04/09/21
Fly Intel: Top five analyst downgrades
04/09/21 Morgan Stanley
Credit Suisse downgraded to Equal Weight from Overweight at Morgan Stanley
04/07/21 RBC Capital
Credit Suisse price target lowered to CHF 11 from CHF 14.50 at RBC Capital
CS Credit Suisse
$10.72 /

+0.08 (+0.75%)

CS Credit Suisse
$10.72 /

+0.08 (+0.75%)

CS Credit Suisse
$10.72 /

+0.08 (+0.75%)

CS Credit Suisse
$10.72 /

+0.08 (+0.75%)

Upgrade
Deutsche upgrades CommScope to Buy on 'significantly positive' spinoff » 06:33
04/13/21
04/13
06:33
04/13/21
06:33
COMM

CommScope

$17.29 /

-0.21 (-1.20%)

Deutsche Bank analyst…

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COMM CommScope
$17.29 /

-0.21 (-1.20%)

COMM CommScope
$17.29 /

-0.21 (-1.20%)

04:47 Today Deutsche Bank
CommScope upgraded to Buy from Hold at Deutsche Bank
04/09/21 Wolfe Research
CommScope price target raised to $23 from $20 at Wolfe Research
04/08/21 Rosenblatt
CommScope upgraded to Buy at Rosenblatt on spinout and industry catalysts
04/08/21 Rosenblatt
CommScope upgraded to Buy from Neutral at Rosenblatt
COMM CommScope
$17.29 /

-0.21 (-1.20%)

COMM CommScope
$17.29 /

-0.21 (-1.20%)

Hot Stocks
Eli Lilly announces Diogo Rau as chief information, digital officer » 06:33
04/13/21
04/13
06:33
04/13/21
06:33
LLY

Eli Lilly

$181.76 /

-2.71 (-1.47%)

, AAPL

Apple

$131.27 /

-1.72 (-1.29%)

Eli Lilly (LLY) announced…

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LLY Eli Lilly
$181.76 /

-2.71 (-1.47%)

AAPL Apple
$131.27 /

-1.72 (-1.29%)

LLY Eli Lilly
$181.76 /

-2.71 (-1.47%)

04/12/21 Benchmark
Benchmark sees full FDA approval of Regeneron's REGEN-COV coming
04/06/21 JPMorgan
JPMorgan survey 'broadly positive' on Eli Lilly Alzheimer's drug
03/24/21 BMO Capital
AbCellera price target lowered to $59 from $61 at BMO Capital
03/17/21 Mizuho
AbbVie's FDA request show Xeljanz concerns may bleed to Rinvoq, says Mizuho
AAPL Apple
$131.27 /

-1.72 (-1.29%)

04/12/21 Canaccord
Canaccord upgrades Tesla with over $1,000 target on 'Apple-esque' ecosystem
04/09/21 Citi
Citi tells investors to focus on Apple's capital deployment, iPhone gains
04/08/21 Piper Sandler
Teen iPhone ownership continues to increase, says Piper Sandler
04/06/21 Cowen
Apple's News product a key growth pillar, says Cowen
LLY Eli Lilly
$181.76 /

-2.71 (-1.47%)

AAPL Apple
$131.27 /

-1.72 (-1.29%)

LLY Eli Lilly
$181.76 /

-2.71 (-1.47%)

AAPL Apple
$131.27 /

-1.72 (-1.29%)

LLY Eli Lilly
$181.76 /

-2.71 (-1.47%)

AAPL Apple
$131.27 /

-1.72 (-1.29%)

LLY Eli Lilly
$181.76 /

-2.71 (-1.47%)

AAPL Apple
$131.27 /

-1.72 (-1.29%)

Hot Stocks
Jowell Global announces strategic cooperation agreement with ZTO Express » 06:33
04/13/21
04/13
06:33
04/13/21
06:33
JWEL

Jowell Global

$8.15 /

+0.4 (+5.16%)

, ZTO

ZTO Express

$28.53 /

+0.32 (+1.13%)

Jowell Global (JWEL)…

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ZTO ZTO Express
$28.53 /

+0.32 (+1.13%)

JWEL Jowell Global
$8.15 /

+0.4 (+5.16%)

ZTO ZTO Express
$28.53 /

+0.32 (+1.13%)

03/22/21 JPMorgan
ZTO Express downgraded to Neutral from Overweight at JPMorgan
11/19/20 HSBC
ZTO Express downgraded to Reduce from Hold at HSBC
11/19/20 Daiwa
ZTO Express downgraded to Outperform from Buy at Daiwa
09/28/20 Bocom
ZTO Express initiated with a Buy at Bocom
  • 17
    Mar
JWEL Jowell Global
$8.15 /

+0.4 (+5.16%)

ZTO ZTO Express
$28.53 /

+0.32 (+1.13%)

Initiation
Benchmark starts Faraday Future partner Property Solutions Acquisition at Buy » 06:32
04/13/21
04/13
06:32
04/13/21
06:32
PSAC

Property Solutions Acquisition

$13.00 /

-1.985 (-13.25%)

As previously reported,…

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PSAC Property Solutions Acquisition
$13.00 /

-1.985 (-13.25%)

PSAC Property Solutions Acquisition
$13.00 /

-1.985 (-13.25%)

06:22 Today Benchmark
Property Solutions Acquisition initiated with a Buy at Benchmark
PSAC Property Solutions Acquisition
$13.00 /

-1.985 (-13.25%)

Hot Stocks
Avenue Therapeutics: FDA still reviewing NDA resubmission for IV tramadol » 06:32
04/13/21
04/13
06:32
04/13/21
06:32
ATXI

Avenue Therapeutics

$7.11 /

+0.215 (+3.12%)

Avenue Therapeutics…

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ATXI Avenue Therapeutics
$7.11 /

+0.215 (+3.12%)

ATXI Avenue Therapeutics
$7.11 /

+0.215 (+3.12%)

03/01/21 H.C. Wainwright
InvaGen takeout 'may still be in play' at Avenue, says H.C. Wainwright
02/17/21 Dawson James
Fortress Biotech price target raised to $21 from $16 at Dawson James
10/12/20 H.C. Wainwright
Avenue downgraded to Neutral on merger uncertainty at H.C. Wainwright
10/12/20 H.C. Wainwright
Avenue Therapeutics downgraded to Neutral from Buy at H.C. Wainwright
Downgrade
Aphria downgraded to Hold from Speculative Buy at Canaccord » 06:31
04/13/21
04/13
06:31
04/13/21
06:31
APHA

Aphria

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+

Canaccord analyst Matt…

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APHA Aphria
/

+

APHA Aphria
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04/12/21 Alliance Global Partners
Alliance Global trims Aphria price target to C$24, says long-term view intact
04/08/21 Alliance Global Partners
Aphria price target raised to $26 from $20 at Alliance Global Partners
04/06/21 Stifel
Aphria price target raised to C$22 from C$15.50 at Stifel
03/29/21 Stifel
Stifel says New York adult use cannabis market represents $5B opportunity
APHA Aphria
/

+

APHA Aphria
/

+

APHA Aphria
/

+

APHA Aphria
/

+

Downgrade
Norilsk Nickel downgraded to Hold from Buy at Societe Generale » 06:31
04/13/21
04/13
06:31
04/13/21
06:31
NILSY

Norilsk Nickel

$32.69 /

+1.22 (+3.88%)

Societe Generale analyst…

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NILSY Norilsk Nickel
$32.69 /

+1.22 (+3.88%)

04/09/21 UBS
Norilsk Nickel downgraded to Neutral from Buy at UBS
03/12/21 Exane BNP Paribas
Norilsk Nickel upgraded to Outperform from Neutral at Exane BNP Paribas
02/22/21 JPMorgan
Norilsk Nickel downgraded to Neutral from Overweight at JPMorgan
11/04/20 Societe Generale
Norilsk Nickel selloff looks overdone, says Societe Generale, upgrades to Buy
Periodicals
Black attended Apollo Global meeting days after resignation, FT reports » 06:29
04/13/21
04/13
06:29
04/13/21
06:29
APO

Apollo Global

$47.59 /

+0.59 (+1.26%)

Days after resigning from…

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APO Apollo Global
$47.59 /

+0.59 (+1.26%)

APO Apollo Global
$47.59 /

+0.59 (+1.26%)

04/12/21 Wells Fargo
Apollo Global price target lowered to $57 from $62 at Wells Fargo
04/09/21 Deutsche Bank
Apollo Global price target lowered to $49 from $52 at Deutsche Bank
04/05/21 JPMorgan
Athene Holding downgraded to Neutral from Overweight at JPMorgan
03/23/21
Fly Intel: Top five analyst upgrades
APO Apollo Global
$47.59 /

+0.59 (+1.26%)

APO Apollo Global
$47.59 /

+0.59 (+1.26%)

APO Apollo Global
$47.59 /

+0.59 (+1.26%)

APO Apollo Global
$47.59 /

+0.59 (+1.26%)

Periodicals
Pinterest to add guidelines for influencers to ensure positivity, WSJ reports » 06:27
04/13/21
04/13
06:27
04/13/21
06:27
PINS

Pinterest

$83.97 /

-1.6 (-1.87%)

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PINS Pinterest
$83.97 /

-1.6 (-1.87%)

PINS Pinterest
$83.97 /

-1.6 (-1.87%)

04/05/21 Evercore ISI
Pinterest initiated with an Outperform at Evercore ISI
03/30/21 Morgan Stanley
Pinterest price target lowered to $89 from $95 at Morgan Stanley
03/22/21 BofA
Pinterest downgraded to Neutral from Buy at BofA
03/22/21 BofA
Pinterest downgraded to Neutral from Buy at BofA
PINS Pinterest
$83.97 /

-1.6 (-1.87%)

PINS Pinterest
$83.97 /

-1.6 (-1.87%)

PINS Pinterest
$83.97 /

-1.6 (-1.87%)

PINS Pinterest
$83.97 /

-1.6 (-1.87%)

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