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CCXI

ChemoCentryx

$53.79 /

+1.61 (+3.09%)

08:38
05/18/20
05/18
08:38
05/18/20
08:38

ChemoCentryx, VFMCRP announce data from Phase II ILUMINA-1 trial

ChemoCentryx and Vifor Fresenius Medical Care Renal Pharma announced topline data from a forty-six patient Phase II dose-ranging trial in the orphan kidney disorder, primary Focal Segmental Glomerulosclerosis. The LUMINA-1 trial tested CCX140, an orally-administered selective inhibitor of the chemokine receptor known as CCR2, in primary FSGS subjects. In the study, CCX140 did not demonstrate a meaningful reduction in proteinuria relative to the control group after 12 weeks of blinded treatment. LUMINA-1 was a dose-ranging Phase II study enrolling 46 patients with primary FSGS. The primary efficacy measure was a change in proteinuria from baseline to week 12. At week 12, all subjects including those in the placebo group were then treated with the highest dose of CCX140, 15 mg twice-daily for an additional 12 weeks of treatment, after which UPCR changes from week 12 to week 24 were also assessed. In the intent to treat analysis of UPCR changes at week 12 relative to baseline, the 15 mg BID CCX140 group exhibited the greatest reduction of UPCR, but that did not differ significantly from the placebo group. Also, after crossover of the blinded portion of the trial to 15 mg BID active dosing, the previous placebo group did not appear to exhibit an additional reduction of UPCR. CCX140 at all doses was well-tolerated, with no serious adverse events during the blinded trial and a numerically lower rate of treatment-emergent adverse events in the CCX140 treatment groups than in the placebo group. A full analysis of the LUMINA-1 data is underway and expanded results are expected to be announced at a medical meeting later this year.

  • 21

    May

CCXI ChemoCentryx
$53.79 /

+1.61 (+3.09%)

05/12/20 SVB Leerink
ChemoCentryx price target raised to $65 from $54 at SVB Leerink
05/12/20 Raymond James
ChemoCentryx price target raised to $102 from $38 at Raymond James
05/12/20 H.C. Wainwright
ChemoCentryx price target raised to $69 from $60 at H.C. Wainwright
05/11/20 Piper Sandler
Piper Sandler expects positive Phase II LUMINA-1 data for ChemoCentryx

TODAY'S FREE FLY STORIES

Hot Stocks
Range Resources falls -16.1% » 12:00
10/30/20
10/30
12:00
10/30/20
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RRC

Range Resources

$6.52 /

-1.25 (-16.09%)

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RRC Range Resources
$6.52 /

-1.25 (-16.09%)

RRC Range Resources
$6.52 /

-1.25 (-16.09%)

10/26/20 BofA
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10/26/20 BofA
Range Resources upgraded to Buy from Neutral at BofA
10/21/20 Raymond James
Range Resources upgraded to Market Perform from Underperform at Raymond James
10/08/20 Stifel
Range Resources resumed with a Hold at Stifel
RRC Range Resources
$6.52 /

-1.25 (-16.09%)

RRC Range Resources
$6.52 /

-1.25 (-16.09%)

RRC Range Resources
$6.52 /

-1.25 (-16.09%)

RRC Range Resources
$6.52 /

-1.25 (-16.09%)

Hot Stocks
Daimler Trucks acquires minority stake in Luminar as part of partnership pact » 12:00
10/30/20
10/30
12:00
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DDAIF

Daimler AG

$0.00 /

+ (+0.00%)

, LAZR

Luminar

$0.00 /

+ (+0.00%)

, GMHI

Gores Metropoulos

$10.08 /

-0.01 (-0.10%)

Luminar Technologies and…

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DDAIF Daimler AG
$0.00 /

+ (+0.00%)

GMHI Gores Metropoulos
$10.08 /

-0.01 (-0.10%)

DDAIF Daimler AG
$0.00 /

+ (+0.00%)

10/26/20 RBC Capital
Daimler AG price target raised to EUR 64 from EUR 60 at RBC Capital
10/20/20 Morgan Stanley
Daimler AG price target raised to EUR 58 from EUR 55 at Morgan Stanley
10/16/20 Pareto
Daimler AG upgraded to Hold from Sell at Pareto
10/15/20 UBS
Daimler AG price target raised to EUR 50 from EUR 41 at UBS
LAZR Luminar
$0.00 /

+ (+0.00%)

GMHI Gores Metropoulos
$10.08 /

-0.01 (-0.10%)

10/14/20 Northland
Gores Metropoulos initiated with an Outperform at Northland
DDAIF Daimler AG
$0.00 /

+ (+0.00%)

DDAIF Daimler AG
$0.00 /

+ (+0.00%)

DDAIF Daimler AG
$0.00 /

+ (+0.00%)

GMHI Gores Metropoulos
$10.08 /

-0.01 (-0.10%)

GMHI Gores Metropoulos
$10.08 /

-0.01 (-0.10%)

Hot Stocks
Twitter falls -20.6% » 12:00
10/30/20
10/30
12:00
10/30/20
12:00
TWTR

Twitter

$41.60 /

-10.85 (-20.69%)

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TWTR Twitter
$41.60 /

-10.85 (-20.69%)

TWTR Twitter
$41.60 /

-10.85 (-20.69%)

07:55 Today Oppenheimer
Twitter price target raised to $55 from $46 at Oppenheimer
07:21 Today Deutsche Bank
Twitter price target raised to $64 from $56 at Deutsche Bank
06:51 Today Mizuho
Twitter price target raised to $48 from $45 at Mizuho
06:28 Today Barclays
Twitter price target raised to $36 from $30 at Barclays
TWTR Twitter
$41.60 /

-10.85 (-20.69%)

TWTR Twitter
$41.60 /

-10.85 (-20.69%)

TWTR Twitter
$41.60 /

-10.85 (-20.69%)

TWTR Twitter
$41.60 /

-10.85 (-20.69%)

Recommendations
First Quantum Minerals price target raised to C$17 from C$16 at RBC Capital » 12:00
10/30/20
10/30
12:00
10/30/20
12:00
FQVLF

First Quantum Minerals

$0.00 /

+ (+0.00%)

RBC Capital analyst Sam…

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FQVLF First Quantum Minerals
$0.00 /

+ (+0.00%)

FQVLF First Quantum Minerals
$0.00 /

+ (+0.00%)

11:44 Today National Bank
First Quantum price target raised to C$19 from C$18.50 at National Bank
10/29/20 TD Securities
First Quantum Minerals price target raised to C$20 from C$19 at TD Securities
10/14/20 Canaccord
First Quantum Minerals price target lowered to C$17 from C$18 at Canaccord
10/13/20 Scotiabank
First Quantum Minerals price target raised to C$17 from C$15 at Scotiabank
Hot Stocks
Pitney Bowes falls -21.9% » 12:00
10/30/20
10/30
12:00
10/30/20
12:00
PBI

Pitney Bowes

$5.80 /

-1.62 (-21.83%)

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PBI Pitney Bowes
$5.80 /

-1.62 (-21.83%)

PBI Pitney Bowes
$5.80 /

-1.62 (-21.83%)

08/04/20 National Securities
Pitney Bowes price target raised to $6 from $5 at National Securities
08/03/20 National Securities
Pitney Bowes upgraded to Buy from Neutral at National Securities
05/05/20 National Securities
Pitney Bowes downgraded to Neutral from Buy at National Securities
PBI Pitney Bowes
$5.80 /

-1.62 (-21.83%)

PBI Pitney Bowes
$5.80 /

-1.62 (-21.83%)

PBI Pitney Bowes
$5.80 /

-1.62 (-21.83%)

Hot Stocks
Invacare rises 12.4% » 12:00
10/30/20
10/30
12:00
10/30/20
12:00
IVC

Invacare

$8.06 /

+0.89 (+12.41%)

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IVC Invacare
$8.06 /

+0.89 (+12.41%)

IVC Invacare
$8.06 /

+0.89 (+12.41%)

Hot Stocks
Regional Management rises 13.1% » 12:00
10/30/20
10/30
12:00
10/30/20
12:00
RM

Regional Management

$22.52 /

+2.93 (+14.96%)

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RM Regional Management
$22.52 /

+2.93 (+14.96%)

RM Regional Management
$22.52 /

+2.93 (+14.96%)

05/14/20 BMO Capital
BMO Capital upgrades Regional Management to Outperform, sees potential to double
05/14/20 BMO Capital
Regional Management upgraded to Outperform from Market Perform at BMO Capital
05/07/20 JMP Securities
Regional Management price target lowered to $20 from $35 at JMP Securities
RM Regional Management
$22.52 /

+2.93 (+14.96%)

Hot Stocks
Rogers Corporation rises 19.7% » 12:00
10/30/20
10/30
12:00
10/30/20
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ROG

Rogers Corporation

$123.28 /

+19.82 (+19.16%)

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ROG Rogers Corporation
$123.28 /

+19.82 (+19.16%)

ROG Rogers Corporation
$123.28 /

+19.82 (+19.16%)

07/31/20 B. Riley FBR
Rogers Corporation price target lowered to $155 from $160 at B. Riley FBR
07/23/20 B. Riley FBR
Rogers Corporation price target raised to $160 from $145 at B. Riley FBR
ROG Rogers Corporation
$123.28 /

+19.82 (+19.16%)

ROG Rogers Corporation
$123.28 /

+19.82 (+19.16%)

Recommendations
Centamin price target lowered to 145 GBp from 160 GBp at RBC Capital » 11:59
10/30/20
10/30
11:59
10/30/20
11:59
CELTF

Centamin

$0.00 /

+ (+0.00%)

RBC Capital analyst Tyler…

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CELTF Centamin
$0.00 /

+ (+0.00%)

CELTF Centamin
$0.00 /

+ (+0.00%)

10/23/20 Berenberg
Centamin price target lowered to EUR 142 from EUR 174 at Berenberg
10/21/20 BMO Capital
Centamin price target lowered to 175 GBp from 200 GBp at BMO Capital
10/06/20 Berenberg
Centamin price target lowered to 174 GBp from 221 GBp at Berenberg
10/06/20 BMO Capital
Centamin price target lowered to 200 GBp from 250 GBp at BMO Capital
Recommendations
Canadian Utilities price target lowered to C$37 from C$38 at RBC Capital » 11:59
10/30/20
10/30
11:59
10/30/20
11:59
CDUAF

Canadian Utilities

$0.00 /

+ (+0.00%)

RBC Capital analyst…

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CDUAF Canadian Utilities
$0.00 /

+ (+0.00%)

10:55 Today TD Securities
Canadian Utilities price target lowered to C$38 from C$40 at TD Securities
07/31/20 RBC Capital
Canadian Utilities price target lowered to C$38 from C$39 at RBC Capital
07/31/20 TD Securities
Canadian Utilities price target raised to C$40 from C$39 at TD Securities
07/31/20 Industrial Alliance
Canadian Utilities downgraded to Hold from Buy at Industrial Alliance
Options
Expedia put volume heavy and directionally bearish » 11:55
10/30/20
10/30
11:55
10/30/20
11:55
EXPE

Expedia

$93.97 /

-1.32 (-1.39%)

Bearish flow noted in…

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EXPE Expedia
$93.97 /

-1.32 (-1.39%)

EXPE Expedia
$93.97 /

-1.32 (-1.39%)

10/19/20 Truist
Expedia price target raised to $143 from $138 at Truist
09/28/20
Fly Intel: Top five analyst downgrades
09/28/20 RBC Capital
Expedia downgraded to Sector Perform from Outperform at RBC Capital
09/28/20 RBC Capital
Expedia downgraded to Sector Perform from Outperform at RBC Capital
EXPE Expedia
$93.97 /

-1.32 (-1.39%)

EXPE Expedia
$93.97 /

-1.32 (-1.39%)

EXPE Expedia
$93.97 /

-1.32 (-1.39%)

EXPE Expedia
$93.97 /

-1.32 (-1.39%)

Hot Stocks
Digital Ally announces multi-year upgrade order from Suwanee PD » 11:51
10/30/20
10/30
11:51
10/30/20
11:51
DGLY

Digital Ally

$2.25 /

-0.1 (-4.26%)

Digital Ally announced a…

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DGLY Digital Ally
$2.25 /

-0.1 (-4.26%)

DGLY Digital Ally
$2.25 /

-0.1 (-4.26%)

06/29/20 Aegis
Digital Ally initiated with a Buy at Aegis
DGLY Digital Ally
$2.25 /

-0.1 (-4.26%)

  • 08
    Jun
  • 02
    Jun
  • 28
    Feb
DGLY Digital Ally
$2.25 /

-0.1 (-4.26%)

DGLY Digital Ally
$2.25 /

-0.1 (-4.26%)

Recommendations
OceanaGold price target lowered to C$2.65 from C$3.25 at CIBC » 11:50
10/30/20
10/30
11:50
10/30/20
11:50
OCANF

OceanaGold

$0.00 /

+ (+0.00%)

CIBC analyst Cosmos Chiu…

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OCANF OceanaGold
$0.00 /

+ (+0.00%)

10/20/20 National Bank
OceanaGold price target lowered to C$4.25 from C$5 at National Bank
10/01/20 RBC Capital
OceanaGold price target lowered to A$4 from A$5 at RBC Capital
09/24/20 Raymond James
OceanaGold downgraded to Outperform from Strong Buy at Raymond James
09/23/20 Raymond James
OceanaGold downgraded to Outperform from Strong Buy at Raymond James
Recommendations
Morguard REIT price target lowered to C$6 from C$7 at CIBC » 11:49
10/30/20
10/30
11:49
10/30/20
11:49
MGRUF

Morguard REIT

$0.00 /

+ (+0.00%)

CIBC analyst Chris…

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MGRUF Morguard REIT
$0.00 /

+ (+0.00%)

08/04/20 RBC Capital
Morguard REIT price target lowered to C$6 from C$6.50 at RBC Capital
05/04/20 RBC Capital
Morguard REIT price target lowered to C$6.50 from C$12.50 at RBC Capital
04/09/20 BMO Capital
Morguard REIT downgraded to Underperform from Market Perform at BMO Capital
Hot Stocks
HHS taps McKesson to supply, distribute COVID-19 vaccine supply kits » 11:49
10/30/20
10/30
11:49
10/30/20
11:49
MCK

McKesson

$144.41 /

+0.57 (+0.40%)

, SPX

S&P 500

$0.00 /

+ (+0.00%)

, SPY

SPDR S&P 500 ETF Trust

$324.00 /

-5.97 (-1.81%)

In support of Operation…

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MCK McKesson
$144.41 /

+0.57 (+0.40%)

SPX S&P 500
$0.00 /

+ (+0.00%)

SPY SPDR S&P 500 ETF Trust
$324.00 /

-5.97 (-1.81%)

MCK McKesson
$144.41 /

+0.57 (+0.40%)

08/04/20
Fly Intel: Top five analyst upgrades
08/04/20 JPMorgan
McKesson price target raised to $198 from $187 at JPMorgan
08/04/20 Deutsche Bank
Deutsche Bank upgrades McKesson to Buy after 'solid' Q1 beat
08/04/20 Deutsche Bank
McKesson upgraded to Buy from Hold at Deutsche Bank
SPX S&P 500
$0.00 /

+ (+0.00%)

09/01/20
Fed's Brainard says monetary policy to pivot from stabilization to accommodation
08/17/20 Goldman Sachs
Goldman boosts end of 2020 S&P 500 target to 3,600 from 3,000
06/04/20 Keefe Bruyette
Mattis rebuke 'wake up call' for stock market, says Keefe Bruyette
03/11/20 Goldman Sachs
Goldman Sachs believes the S&P 500 bull market will soon end
SPY SPDR S&P 500 ETF Trust
$324.00 /

-5.97 (-1.81%)

09/01/20
Fed's Brainard says monetary policy to pivot from stabilization to accommodation
08/17/20 Goldman Sachs
Goldman boosts end of 2020 S&P 500 target to 3,600 from 3,000
06/04/20 Keefe Bruyette
Mattis rebuke 'wake up call' for stock market, says Keefe Bruyette
03/11/20 Goldman Sachs
Goldman Sachs believes the S&P 500 bull market will soon end
MCK McKesson
$144.41 /

+0.57 (+0.40%)

MCK McKesson
$144.41 /

+0.57 (+0.40%)

SPX S&P 500
$0.00 /

+ (+0.00%)

SPY SPDR S&P 500 ETF Trust
$324.00 /

-5.97 (-1.81%)

MCK McKesson
$144.41 /

+0.57 (+0.40%)

MCK McKesson
$144.41 /

+0.57 (+0.40%)

SPX S&P 500
$0.00 /

+ (+0.00%)

SPY SPDR S&P 500 ETF Trust
$324.00 /

-5.97 (-1.81%)

SPX S&P 500
$0.00 /

+ (+0.00%)

SPY SPDR S&P 500 ETF Trust
$324.00 /

-5.97 (-1.81%)

Recommendations
Allied Properties price target lowered to C$43 from C$46.50 at CIBC » 11:48
10/30/20
10/30
11:48
10/30/20
11:48
APYRF

Allied Properties Real Estate

$0.00 /

+ (+0.00%)

CIBC analyst Chris…

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APYRF Allied Properties Real Estate
$0.00 /

+ (+0.00%)

11:23 Today Canaccord
Allied Properties price target lowered to C$45 from C$50 at Canaccord
10:58 Today TD Securities
Allied Properties price target lowered to C$45 from C$52 at TD Securities
10/26/20 National Bank
Allied Properties price target lowered to C$48 from C$54 at National Bank
10/23/20 Scotiabank
Allied Properties price target lowered to C$48 from C$53.50 at Scotiabank
Hot Stocks
Amazon to create 500 full-time jobs with North Dakota fulfillment center » 11:47
10/30/20
10/30
11:47
10/30/20
11:47
AMZN

Amazon.com

$3,072.00 /

-144.26 (-4.49%)

Amazon.com plans to open…

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AMZN Amazon.com
$3,072.00 /

-144.26 (-4.49%)

AMZN Amazon.com
$3,072.00 /

-144.26 (-4.49%)

10:16 Today Bernstein
Amazon.com price target raised to $3,700 from $3,400 at Bernstein
09:14 Today R5 Capital
R5 Capital upgrades Amazon to Hold after 'total bust' calling for growth to slow
08:44 Today R5 Capital
Amazon.com upgraded to Hold from Sell at R5 Capital
08:40 Today MKM Partners
Amazon.com price target raised to $3,750 from $3,650 at MKM Partners
AMZN Amazon.com
$3,072.00 /

-144.26 (-4.49%)

AMZN Amazon.com
$3,072.00 /

-144.26 (-4.49%)

AMZN Amazon.com
$3,072.00 /

-144.26 (-4.49%)

AMZN Amazon.com
$3,072.00 /

-144.26 (-4.49%)

AMZN Amazon.com
$3,072.00 /

-144.26 (-4.49%)

Recommendations
Osisko Gold price target raised to C$23 from C$22 at National Bank » 11:46
10/30/20
10/30
11:46
10/30/20
11:46
OR

Osisko Gold

$10.96 /

-0.17 (-1.53%)

National Bank analyst…

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OR Osisko Gold
$10.96 /

-0.17 (-1.53%)

OR Osisko Gold
$10.96 /

-0.17 (-1.53%)

10/29/20 RBC Capital
Osisko Gold assumed with an Outperform at RBC Capital
10/13/20 Scotiabank
Osisko Gold price target raised to C$24 from C$21 at Scotiabank
09/16/20 CIBC
Osisko Gold price target raised to C$19.75 from C$17.50 at CIBC
09/11/20 National Bank
Osisko Gold price target raised to C$22 from C$21 at National Bank
OR Osisko Gold
$10.96 /

-0.17 (-1.53%)

Syndicate
Atea Pharmaceuticals indicated to open at $24.50, IPO priced at $24  11:46
10/30/20
10/30
11:46
10/30/20
11:46
AVIR

Atea Pharmaceuticals

$0.00 /

+ (+0.00%)

 
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  • 30
    Oct
Recommendations
North American Construction price target raised to C$17 at National Bank » 11:46
10/30/20
10/30
11:46
10/30/20
11:46
NOA

North American Construction

$7.62 /

-0.23 (-2.93%)

National Bank analyst…

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NOA North American Construction
$7.62 /

-0.23 (-2.93%)

NOA North American Construction
$7.62 /

-0.23 (-2.93%)

11:25 Today Raymond James
North American Construction price target raised to C$10 at Raymond James
10/23/20 TD Securities
TD upgrades North American Construction to Buy on 'very important' contract
10/22/20 TD Securities
North American Construction upgraded to Buy from Hold at TD Securities
08/17/20 TD Securities
North American Construction downgraded to Hold from Buy at TD Securities
NOA North American Construction
$7.62 /

-0.23 (-2.93%)

Options
Matador call volume above normal and directionally bullish » 11:45
10/30/20
10/30
11:45
10/30/20
11:45
MTDR

Matador

$6.72 /

-0.185 (-2.68%)

Bullish option flow…

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MTDR Matador
$6.72 /

-0.185 (-2.68%)

MTDR Matador
$6.72 /

-0.185 (-2.68%)

09/22/20 Truist
Matador upgraded to Buy from Hold at Truist
09/22/20 Truist
Matador upgraded to Buy from Hold at Truist
09/14/20 Wells Fargo
Matador upgraded to Overweight from Equal Weight at Wells Fargo
07/29/20 Northland
Matador guidance seems conservative after 'big beat' in Q2, says Northland
MTDR Matador
$6.72 /

-0.185 (-2.68%)

MTDR Matador
$6.72 /

-0.185 (-2.68%)

MTDR Matador
$6.72 /

-0.185 (-2.68%)

Recommendations
Gildan Activewear price target raised to C$33 from C$31 at National Bank » 11:45
10/30/20
10/30
11:45
10/30/20
11:45
GIL

Gildan Activewear

$21.13 /

-0.24 (-1.12%)

National Bank analyst…

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GIL Gildan Activewear
$21.13 /

-0.24 (-1.12%)

GIL Gildan Activewear
$21.13 /

-0.24 (-1.12%)

11:22 Today CIBC
CIBC upgrades 'fundamentally stronger' Gildan Activewear to Outperformer
09:56 Today
Fly Intel: Top five analyst upgrades
07:29 Today RBC Capital
Gildan Activewear upgraded to Outperform from Sector Perform at RBC Capital
04:58 Today BMO Capital
Gildan Activewear upgraded to Outperform from Market Perform at BMO Capital
GIL Gildan Activewear
$21.13 /

-0.24 (-1.12%)

Recommendations
First Quantum price target raised to C$19 from C$18.50 at National Bank » 11:44
10/30/20
10/30
11:44
10/30/20
11:44
FQVLF

First Quantum Minerals

$0.00 /

+ (+0.00%)

National Bank analyst…

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FQVLF First Quantum Minerals
$0.00 /

+ (+0.00%)

FQVLF First Quantum Minerals
$0.00 /

+ (+0.00%)

10/29/20 TD Securities
First Quantum Minerals price target raised to C$20 from C$19 at TD Securities
10/14/20 Canaccord
First Quantum Minerals price target lowered to C$17 from C$18 at Canaccord
10/13/20 Scotiabank
First Quantum Minerals price target raised to C$17 from C$15 at Scotiabank
09/24/20 Morgan Stanley
First Quantum Minerals price target raised to C$18 from C$13 at Morgan Stanley
Syndicate
Lufax opens at $11.60, IPO priced at $13.50 per share  11:42
10/30/20
10/30
11:42
10/30/20
11:42
LU

Lufax

$0.00 /

+ (+0.00%)

 
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  • 30
    Oct
Hot Stocks
Disney warns of 11,350 union employees to be laid off in Florida parks » 11:41
10/30/20
10/30
11:41
10/30/20
11:41
DIS

Disney

$119.82 /

-1.71 (-1.41%)

Walt Disney Company…

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DIS Disney
$119.82 /

-1.71 (-1.41%)

DIS Disney
$119.82 /

-1.71 (-1.41%)

10/13/20
Fly Intel: Top five analyst upgrades
10/13/20 RBC Capital
EPR Properties downgraded to Sector Perform from Outperform at RBC Capital
10/13/20 Morgan Stanley
Disney reorg 'leaves little doubt' about DTC commitment, says Morgan Stanley
10/13/20 Loop Capital
Disney upgraded to Buy from Hold at Loop Capital
DIS Disney
$119.82 /

-1.71 (-1.41%)

DIS Disney
$119.82 /

-1.71 (-1.41%)

DIS Disney
$119.82 /

-1.71 (-1.41%)

DIS Disney
$119.82 /

-1.71 (-1.41%)

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