2020-05-28 08:15:32 CLVS Clovis
05/28/20 05/2808:15 05/28/2008:15 | Clovis announces updated NCCN guidelines for Rubraca tabletsClovis announced that the National Comprehensive Cancer Network, or NCCN, updated its clinical practice guidelines in Oncology for Prostate Cancer to include new recommendations for Rubraca tablets. In addition to its ovarian cancer recommendations, Rubraca is now recommended in the NCCN Guidelines for the treatment of BRCA-mutant patients with mCRPC under second-line treatment and subsequent therapy as a Category 2A recommendation. Rucaparib is a treatment option for patients with mCRPC and a pathogenic BRCA1 or BRCA2 mutation who have been treated with androgen receptor-directed therapy and a taxane-based chemotherapy. If the patient is not fit for chemotherapy, rucaparib can be considered even if taxane-based therapy has not been given. The NCCN prostate cancer panel's decision to include Rubraca as a Category 2A preferred option for the treatment of patients with a BRCA mutation for second-line treatment and subsequent therapy was based on the results of the Phase 2 TRITON2 study. |
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