2020-08-10 06:37:53 PIRS Pieris Pharmaceuticals
Eli Lilly
08/10/20 08/1006:37 08/10/2006:37 | Pieris Pharmaceuticals, Eli Lilly enter clinical trial collaborationPieris Pharmaceuticals (PIRS) announced that it has entered into a clinical trial collaboration and supply agreement with Eli Lilly (LLY) to evaluate the safety and efficacy of combining Pieris' PRS-343, a 4-1BB/HER2 bispecific for HER2-positive tumors, with Lilly's ramucirumab, a VEGFR2 antagonist FDA-approved for multiple types of solid tumors, and paclitaxel for the second-line treatment of patients with HER2-positive gastric cancer in a phase 2 study. Under the terms of the agreement, Lilly will supply Pieris with ramucirumab for the study as well as collaborate on data from the trial. Pieris is working towards initiation of a phase 2 single-arm combination study for the second-line treatment of HER2-positive gastric cancer later this year. Pieris Pharmaceuticals
Eli Lilly
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