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EXEL

Exelixis

$26.78 /

-0.16 (-0.59%)

, BMY

Bristol-Myers

$59.26 /

-0.14 (-0.24%)

14:45
09/20/20
09/20
14:45
09/20/20
14:45

Bristol-Myers, Exelixis announce results from Phase 3 CheckMate -9ER trial

Bristol Myers Squibb (BMY) and Exelixis (EXEL) have announced the first presentation of results from the pivotal Phase 3 CheckMate -9ER trial, in which Opdivo in combination with CABOMETYX demonstrated "significant improvements" across all efficacy endpoints, including overall survival, in previously untreated advanced renal cell carcinoma. Opdivo in combination with CABOMETYX reduced the risk of death by 40% vs. sunitinib. In patients receiving Opdivo in combination with CABOMETYX, median progression-free survival, the trial's primary endpoint, was doubled compared to those receiving sunitinib alone: 16.6 months vs. 8.3 months, respectively. In addition, Opdivo in combination with CABOMETYX demonstrated a superior objective response rate, with twice as many patients responding compared to sunitinib, and 8% vs. 5% achieved a complete response. Opdivo in combination with CABOMETYX was associated with a longer duration of response than sunitinib, with a median duration of 20.2 months vs. 11.5 months. All of these key efficacy results were consistent across the pre-specified International Metastatic Renal Cell Carcinoma Database Consortium risk and PD-L1 subgroups. Opdivo combined with CABOMETYX was well tolerated and reflected the known safety profiles of the immunotherapy and tyrosine kinase inhibitor components in previously untreated advanced RCC. The incidence of treatment-related adverse events, including any-grade and high-grade TRAEs, was slightly higher for Opdivo in combination with CABOMETYX vs. sunitinib, with a low rate of treatment-related discontinuations. Patients treated with Opdivo in combination with CABOMETYX reported significantly better health-related quality of life than those treated with sunitinib at most time points, according to National Comprehensive Cancer Network-Functional Assessment of Cancer Therapy Kidney Symptom Index 19 scores. Based on these efficacy and safety results from CheckMate -9ER, Bristol Myers Squibb and Exelixis' partner Ipsen (IPSEY), which has exclusive rights to commercialize and develop CABOMETYX outside of the U.S. and Japan, each submitted type II variation applications for Opdivo plus CABOMETYX to the European Medicines Agency. On September 12, the EMA validated the type II variations, confirming the submissions are complete and beginning the EMA's centralized review process. In addition, Bristol Myers Squibb and Exelixis recently completed their respective U.S. Food and Drug Administration submissions for Opdivo in combination with CABOMETYX and, along with their partners, plan to discuss the CheckMate -9ER data with regulatory authorities across the world.

EXEL

Exelixis

$26.78 /

-0.16 (-0.59%)

BMY

Bristol-Myers

$59.26 /

-0.14 (-0.24%)

IPSEY

Ipsen

$0.00 /

+ (+0.00%)

  • 28

    Sep

EXEL Exelixis
$26.78 /

-0.16 (-0.59%)

06/30/20 Piper Sandler
Exelixis' 2/3 Phase III Contact studies underway, says Piper Sandler
05/14/20 Truist
Exelixis price target raised to $40 from $35 at SunTrust
05/13/20 Piper Sandler
Exelixis mCRPC data for CABOMETYX may accelerate approval, says Piper Sandler
05/06/20 Piper Sandler
Exelixis price target raised to $30 from $23 at Piper Sandler
BMY Bristol-Myers
$59.26 /

-0.14 (-0.24%)

08/25/20 Piper Sandler
Bristol's trial miss has 'no financial impact' on Agios, says Piper Sandler
08/06/20 Citi
Investors can refocus on Bristol-Myers story after Eliquis win, says Citi
07/28/20 Mizuho
Wait for Bristol-Myers' bb2121 submission making some 'nervous,' says Mizuho
07/28/20
Fly Intel: Top five analyst initiations
IPSEY Ipsen
$0.00 /

+ (+0.00%)

09/01/20 Morgan Stanley
Ipsen price target raised to EUR 101 from EUR 90 at Morgan Stanley
08/26/20 JPMorgan
JPMorgan backs Overweight on Ipsen after palovarotene data
08/04/20 UBS
Ipsen price target raised to EUR 101 from EUR 99 at UBS
08/03/20 Credit Suisse
Ipsen price target raised to EUR 86 from EUR 69 at Credit Suisse

TODAY'S FREE FLY STORIES

Recommendations
Centerra Gold price target lowered to C$17 from C$21 at National Bank » 11:48
10/22/20
10/22
11:48
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11:48
CAGDF

Centerra Gold

$0.00 /

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CAGDF Centerra Gold
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CAGDF Centerra Gold
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10/16/20 Raymond James
Centerra Gold price target lowered to C$19.50 from C$23 at Raymond James
10/13/20 Scotiabank
Centerra Gold price target lowered to C$18 from C$18.50 at Scotiabank
09/16/20 CIBC
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08/05/20 TD Securities
Centerra Gold price target raised to C$18 from C$17 at TD Securities
Conference/Events
Credit Suisse technology analyst to hold an analyst/industry conference call » 11:47
10/22/20
10/22
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Recommendations
Spectris price target raised to 3,090 GBp from 2,935 GBp at Jefferies » 11:47
10/22/20
10/22
11:47
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SEPJF

Spectris

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Jefferies analyst Andy…

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SEPJF Spectris
$0.00 /

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10/12/20 Morgan Stanley
Spectris upgraded to Equal Weight from Underweight at Morgan Stanley
09/16/20 UBS
Spectris price target lowered to 2,300 GBp from 2,345 GBp at UBS
06/24/20 JPMorgan
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Spectris price target lowered to 2,250 GBp from 2,350 GBp at JPMorgan
Recommendations
Dundee Precious Metals price target raised to C$14.50 at National Bank » 11:46
10/22/20
10/22
11:46
10/22/20
11:46
DPMLF

Dundee Precious Metals

$0.00 /

+ (+0.00%)

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DPMLF Dundee Precious Metals
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+ (+0.00%)

DPMLF Dundee Precious Metals
$0.00 /

+ (+0.00%)

10/13/20 Scotiabank
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Dundee Precious Metals price target raised to C$12.50 from C$10.50 at CIBC
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Dundee Precious Metals price target raised to C$11.50 from C$11.25 at Canaccord
General news
8-Week Bill Auction Total Amount data reported » 11:46
10/22/20
10/22
11:46
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8-Week Bill Auction Total…

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General news
4-Week Bill Auction Total Amount data reported » 11:46
10/22/20
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Options
Palantir Technologies call volume above normal and directionally bullish » 11:45
10/22/20
10/22
11:45
10/22/20
11:45
PLTR

Palantir

$9.49 /

+0.28 (+3.04%)

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PLTR Palantir
$9.49 /

+0.28 (+3.04%)

PLTR Palantir
$9.49 /

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PLTR Palantir
$9.49 /

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PLTR Palantir
$9.49 /

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Recommendations
Newmont price target lowered to C$121 from C$125 at National Bank » 11:44
10/22/20
10/22
11:44
10/22/20
11:44
NEM

Newmont

$60.16 /

-1.31 (-2.13%)

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NEM Newmont
$60.16 /

-1.31 (-2.13%)

NEM Newmont
$60.16 /

-1.31 (-2.13%)

09/11/20 National Bank
Newmont price target raised to C$125 from C$119 at National Bank
07/20/20 Scotiabank
Yamana downgraded to Sector Perform on valuation at Scotiabank
06/29/20 Citi
Newmont price target lowered to $70 from $74 at Citi
05/18/20 Standpoint Research
Newmont downgraded to Hold from Buy at Standpoint Research
NEM Newmont
$60.16 /

-1.31 (-2.13%)

NEM Newmont
$60.16 /

-1.31 (-2.13%)

NEM Newmont
$60.16 /

-1.31 (-2.13%)

Recommendations
Kirkland Lake Gold price target lowered to C$76 from C$79 at National Bank » 11:42
10/22/20
10/22
11:42
10/22/20
11:42
KL

Kirkland Lake Gold

$47.12 /

-0.93 (-1.94%)

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KL Kirkland Lake Gold
$47.12 /

-0.93 (-1.94%)

KL Kirkland Lake Gold
$47.12 /

-0.93 (-1.94%)

10/13/20 Scotiabank
Kirkland Lake Gold price target raised to C$70 from C$64 at Scotiabank
09/16/20 CIBC
Kirkland Lake Gold price target raised to C$95.50 from C$81 at CIBC
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Kirkland Lake Gold price target raised to C$79 from C$76 at National Bank
07/31/20 CIBC
Kirkland Lake Gold price target raised to C$81 from C$75 at CIBC
KL Kirkland Lake Gold
$47.12 /

-0.93 (-1.94%)

Conference/Events
Piper Sandler pharmaceuticals analysts host analyst/industry conference call » 11:42
10/22/20
10/22
11:42
10/22/20
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Recommendations
Barrick Gold price target lowered to C$42 from C$44 at National Bank » 11:41
10/22/20
10/22
11:41
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11:41
GOLD

Barrick Gold

$26.77 /

-0.6 (-2.19%)

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GOLD Barrick Gold
$26.77 /

-0.6 (-2.19%)

GOLD Barrick Gold
$26.77 /

-0.6 (-2.19%)

09/17/20 Jefferies
Freeport 'not an acquisition target for now,' says Jefferies
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Barrick Gold price target raised to C$44 from C$42 at National Bank
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$26.77 /

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On The Fly
Tesla rises as another earnings beat converts two new bulls » 11:40
10/22/20
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TSLA

Tesla

$432.84 /

+10.235 (+2.42%)

Shares of Tesla (TSLA)…

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TSLA Tesla
$432.84 /

+10.235 (+2.42%)

TSLA Tesla
$432.84 /

+10.235 (+2.42%)

09:53 Today
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GLJ keeps $40 target on Tesla, says business model not sustainable
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Tesla price target raised to $339 from $290 at RBC Capital
08:45 Today Cowen
Tesla appears to be losing share in China and Europe, says Cowen
TSLA Tesla
$432.84 /

+10.235 (+2.42%)

  • 14
    Feb
TSLA Tesla
$432.84 /

+10.235 (+2.42%)

TSLA Tesla
$432.84 /

+10.235 (+2.42%)

TSLA Tesla
$432.84 /

+10.235 (+2.42%)

Recommendations
Agnico Eagle price target lowered to C$128 from C$130 at National Bank » 11:40
10/22/20
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11:40
10/22/20
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AEM

Agnico Eagle

$79.68 /

-2.04 (-2.50%)

National Bank analyst…

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AEM Agnico Eagle
$79.68 /

-2.04 (-2.50%)

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$79.68 /

-2.04 (-2.50%)

10/19/20 Barclays
Agnico Eagle downgraded to Equal Weight from Overweight at Barclays
09/24/20 Raymond James
Agnico Eagle price target raised to $94 from $82 at Raymond James
07/30/20 Scotiabank
Agnico Eagle upgraded to Outperform with $72 target at Scotiabank
07/30/20 Scotiabank
Agnico Eagle upgraded to Outperform from Sector Perform at Scotiabank
AEM Agnico Eagle
$79.68 /

-2.04 (-2.50%)

AEM Agnico Eagle
$79.68 /

-2.04 (-2.50%)

Hot Stocks
Sony says Netflix, Disney+, Spotify apps available on PS5 at launch » 11:37
10/22/20
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SNE

Sony

$74.43 /

-0.32 (-0.43%)

, AAPL

Apple

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, DIS

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, SPOT

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, AMZN

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, GOOG

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, GOOGL

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$1,596.89 /

+10.14 (+0.64%)

Sony (SNE) announced some…

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SNE Sony
$74.43 /

-0.32 (-0.43%)

AAPL Apple
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GOOGL Alphabet Class A
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SNE Sony
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Sony downgraded to Neutral from Buy at UBS
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10/09/20 Citi
Sony price target lowered to 10,000 yen from 10,300 yen at Citi
AAPL Apple
$115.95 /

-0.93 (-0.80%)

09:37 Today Cleveland Research
Cleveland Research sees further upside for Apple iPhone forecasts
09:32 Today DA Davidson
Apple 'looks good to us', says DA Davidson
07:58 Today Morgan Stanley
Apple iPhone12 cycle early data points trending positively, says Morgan Stanley
06:13 Today Piper Sandler
Apple price target raised to $135 from $130 at Piper Sandler
DIS Disney
$127.45 /

+0.785 (+0.62%)

10/13/20
Fly Intel: Top five analyst upgrades
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NFLX Netflix
$485.82 /

-3.05 (-0.62%)

10/21/20 JPMorgan
Netflix weakness on earnings a buying opportunity, says JPMorgan
10/21/20 KeyBanc
KeyBanc sees Netflix stock weakness as 'an overreaction'
10/21/20 Wells Fargo
Netflix price target raised to $510 from $470 at Wells Fargo
10/21/20 Canaccord
Netflix profits outperformed while subscriber growth slowed, says Canaccord
SPOT Spotify
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-0.655 (-0.24%)

10/14/20 Barclays
Spotify price target raised to $320 from $310 at Barclays
10/06/20 Credit Suisse
Sirius XM upgraded to Outperform from Neutral at Credit Suisse
10/01/20 Pivotal Research
Sirius XM recent pullback a buying opportunity, says Pivotal Research
09/28/20 Guggenheim
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AMZN Amazon.com
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GOOG Alphabet
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Alphabet arguments against lawsuit have merits, says JPMorgan
10/21/20 Morgan Stanley
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GOOGL Alphabet Class A
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+10.14 (+0.64%)

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Alphabet arguments against lawsuit have merits, says JPMorgan
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Google Search should see sharper cyclical recovery, says Credit Suisse
SNE Sony
$74.43 /

-0.32 (-0.43%)

AAPL Apple
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-0.93 (-0.80%)

DIS Disney
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NFLX Netflix
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SPOT Spotify
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AMZN Amazon.com
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GOOG Alphabet
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SNE Sony
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NFLX Netflix
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SPOT Spotify
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AMZN Amazon.com
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GOOG Alphabet
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GOOGL Alphabet Class A
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SNE Sony
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GOOG Alphabet
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SNE Sony
$74.43 /

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AAPL Apple
$115.95 /

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DIS Disney
$127.45 /

+0.785 (+0.62%)

NFLX Netflix
$485.82 /

-3.05 (-0.62%)

SPOT Spotify
$270.67 /

-0.655 (-0.24%)

AMZN Amazon.com
$3,148.00 /

-35.43 (-1.11%)

GOOGL Alphabet Class A
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+10.14 (+0.64%)

AAPL Apple
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-0.93 (-0.80%)

AMZN Amazon.com
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GOOGL Alphabet Class A
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Recommendations
Taseko Mines price target raised to C$1.80 from C$1.75 at National Bank » 11:36
10/22/20
10/22
11:36
10/22/20
11:36
TGB

Taseko Mines

$1.14 /

-0.01 (-0.87%)

National Bank analyst Don…

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TGB Taseko Mines
$1.14 /

-0.01 (-0.87%)

TGB Taseko Mines
$1.14 /

-0.01 (-0.87%)

10/13/20 Scotiabank
Taseko Mines price target raised to C$1 from C$0.80 at Scotiabank
09/11/20 National Bank
Taseko Mines price target raised to C$1.75 from C$1.15 at National Bank
08/06/20 BMO Capital
Taseko Mines price target raised to C$1.25 from C$1.10 at BMO Capital
08/06/20 National Bank
Taseko Mines price target raised to C$1.15 from C$0.95 at National Bank
Options
Seagate put volume heavy and directionally bearish » 11:35
10/22/20
10/22
11:35
10/22/20
11:35
STX

Seagate

$51.55 /

-0.19 (-0.37%)

Bearish flow noted in…

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STX Seagate
$51.55 /

-0.19 (-0.37%)

STX Seagate
$51.55 /

-0.19 (-0.37%)

10/21/20 RBC Capital
Seagate price target raised to $52 from $48 at RBC Capital
10/13/20 Morgan Stanley
Morgan Stanley upgrades IT Hardware industry view to Attractive from In-Line
09/22/20 Susquehanna
Susquehanna updates estimates for Western Digital and Seagate
09/15/20 Northland
Seagate initiated with an Outperform at Northland
STX Seagate
$51.55 /

-0.19 (-0.37%)

STX Seagate
$51.55 /

-0.19 (-0.37%)

STX Seagate
$51.55 /

-0.19 (-0.37%)

STX Seagate
$51.55 /

-0.19 (-0.37%)

Recommendations
Nexa Resources price target lowered to C$10 from C$10.50 at National Bank » 11:33
10/22/20
10/22
11:33
10/22/20
11:33
NEXA

Nexa Resources

$5.75 /

-0.08 (-1.37%)

National Bank analyst…

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NEXA Nexa Resources
$5.75 /

-0.08 (-1.37%)

NEXA Nexa Resources
$5.75 /

-0.08 (-1.37%)

09/11/20 National Bank
Nexa Resources price target raised to C$10.50 from C$8.50 at National Bank
07/21/20 National Bank
Nexa Resources price target raised to C$8.50 from C$6.50 at National Bank
07/07/20 Citi
Nexa Resources price target raised to $6 from $4.50 at Citi
06/22/20 JPMorgan
Nexa Resources downgraded to Neutral with $6.50 target at JPMorgan
NEXA Nexa Resources
$5.75 /

-0.08 (-1.37%)

Recommendations
Hudbay Minerals price target raised to C$7 from C$6.75 at National Bank » 11:32
10/22/20
10/22
11:32
10/22/20
11:32
HBM

Hudbay Minerals

$4.98 /

-0.165 (-3.21%)

National Bank analyst…

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HBM Hudbay Minerals
$4.98 /

-0.165 (-3.21%)

HBM Hudbay Minerals
$4.98 /

-0.165 (-3.21%)

10/13/20 Scotiabank
Hudbay Minerals price target raised to C$7.25 from C$5 at Scotiabank
10/13/20 Scotiabank
Hudbay upgraded to Outperform on copper leverage at Scotiabank
10/13/20 Scotiabank
Hudbay Minerals upgraded to Outperform from Sector Perform at Scotiabank
09/24/20 Raymond James
Hudbay Minerals price target raised to C$6.50 from C$6 at Raymond James
HBM Hudbay Minerals
$4.98 /

-0.165 (-3.21%)

Syndicate
McAfee indicated to open at $18.50, IPO priced at $20  11:31
10/22/20
10/22
11:31
10/22/20
11:31
MCFE

McAfee

$0.00 /

+ (+0.00%)

 
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MCFE McAfee
$0.00 /

+ (+0.00%)

  • 22
    Oct
MCFE McAfee
$0.00 /

+ (+0.00%)

Recommendations
Ero Copper price target raised to C$20.50 from C$19.50 at National Bank » 11:31
10/22/20
10/22
11:31
10/22/20
11:31
ERRPF

Ero Copper

$0.00 /

+ (+0.00%)

National Bank analyst…

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ERRPF Ero Copper
$0.00 /

+ (+0.00%)

ERRPF Ero Copper
$0.00 /

+ (+0.00%)

10/14/20 Canaccord
Ero Copper price target raised to C$23 from C$22 at Canaccord
10/13/20 Scotiabank
Ero Copper price target raised to C$21 from C$20 at Scotiabank
09/24/20 Raymond James
Ero Copper price target raised to C$21.50 from C$21 at Raymond James
09/17/20 CIBC
Ero Copper price target raised to C$21 from C$19 at CIBC
Recommendations
Copper Mountain price target raised to C$1.40 from C$1.25 at National Bank » 11:30
10/22/20
10/22
11:30
10/22/20
11:30
CPPMF

Copper Mountain Mining

$0.00 /

+ (+0.00%)

National Bank analyst Don…

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CPPMF Copper Mountain Mining
$0.00 /

+ (+0.00%)

10/13/20 Scotiabank
Copper Mountain Mining price target raised to C$1.20 from C$0.85 at Scotiabank
09/17/20 CIBC
Copper Mountain Mining price target raised to C$1.20 from C$0.80 at CIBC
09/11/20 National Bank
Copper Mountain Mining price target raised to C$1.25 from C$0.90 at National Bank
07/31/20 Scotiabank
Copper Mountain Mining price target raised to C$0.85 from C$0.75 at Scotiabank
Periodicals
Goldman Sachs to claw back pay from CEO Solomon, former CEO, WSJ reports » 11:26
10/22/20
10/22
11:26
10/22/20
11:26
GS

Goldman Sachs

$204.80 /

+1.9 (+0.94%)

Goldman Sachs will claw…

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GS Goldman Sachs
$204.80 /

+1.9 (+0.94%)

GS Goldman Sachs
$204.80 /

+1.9 (+0.94%)

10/19/20 Credit Suisse
Goldman Sachs price target raised to $262 from $255 at Credit Suisse
10/15/20 BMO Capital
Goldman Sachs price target raised to $274 from $267 at BMO Capital
10/15/20 Oppenheimer
Goldman Sachs price target raised to $356 from $326 at Oppenheimer
10/15/20 Barclays
Goldman Sachs price target raised to $270 from $253 at Barclays
GS Goldman Sachs
$204.80 /

+1.9 (+0.94%)

GS Goldman Sachs
$204.80 /

+1.9 (+0.94%)

GS Goldman Sachs
$204.80 /

+1.9 (+0.94%)

GS Goldman Sachs
$204.80 /

+1.9 (+0.94%)

Recommendations
Capstone Mining price target raised to C$1.80 from C$1.70 at National Bank » 11:26
10/22/20
10/22
11:26
10/22/20
11:26
CSFFF

Capstone Mining

$0.00 /

+ (+0.00%)

National Bank analyst…

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CSFFF Capstone Mining
$0.00 /

+ (+0.00%)

10/13/20 Scotiabank
Capstone Mining price target raised to C$2 from C$1.50 at Scotiabank
09/17/20 CIBC
Capstone Mining price target raised to C$1.90 from C$1.50 at CIBC
09/11/20 National Bank
Capstone Mining price target raised to C$1.70 from C$1.55 at National Bank
09/11/20 CIBC
Capstone Mining price target raised to C$1.50 from C$1.30 at CIBC
General news
Treasury announced a $162 B package of shorter dated coupon auctions » 11:25
10/22/20
10/22
11:25
10/22/20
11:25

Treasury announced a $162…

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Options
Cronos Group call volume above normal and directionally bullish » 11:25
10/22/20
10/22
11:25
10/22/20
11:25
CRON

Cronos Group

$5.90 /

+0.015 (+0.25%)

Bullish option flow…

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CRON Cronos Group
$5.90 /

+0.015 (+0.25%)

CRON Cronos Group
$5.90 /

+0.015 (+0.25%)

09/09/20 Stifel
Cronos CEO transition 'natural part' of company's evolution, says Stifel
08/31/20 Roth Capital
Roth Capital believes MORE Act will not pass in 2020
06/24/20
Fly Intel: Top five analyst upgrades
06/24/20 Raymond James
Cronos Group upgraded to Outperform from Market Perform at Raymond James
CRON Cronos Group
$5.90 /

+0.015 (+0.25%)

CRON Cronos Group
$5.90 /

+0.015 (+0.25%)

CRON Cronos Group
$5.90 /

+0.015 (+0.25%)

CRON Cronos Group
$5.90 /

+0.015 (+0.25%)

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