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ATNF

180 Life Sciences

$2.16 /

-0.28 (-11.48%)

08:41
11/17/20
11/17
08:41
11/17/20
08:41

180 Life Sciences CEO expects operating expenses to remain low relative to peers

180 Life Sciences Corp. released the following letter to stockholders from its CEO Dr. James Woody. The letter read in part, "On the heels of the November 9, 2020, closing of our merger with KBLM Merger Corp IV, resulting in 180 Life Sciences now being a stand-alone publicly traded company and its common stock being listed on The NASDAQ Capital Market under the symbol "ATNF", I wanted to take this opportunity to personally communicate with you. It goes without saying that I appreciate your support in helping us get to where we are today and want to update you on our planned path moving forward...I'd like to now tell you a little about our exciting pipeline which includes three clinical programs addressing the following indications: Early Dupuytren's contracture, a fibrotic disease of the hand, which is in Phase 2b/3, with results expected in 2H 2021. Dupuytren's disease is estimated to impact over 11 million Americans, and about the same number in the European Union. Our trial is focused on treating early and preventing the progress of the disease to avoid the hand contracture disability. This project is entirely grant funded. Frozen shoulder, with a grant to initiate the clinical study recently awarded by the National Institute of Health Research, U.K. Due to COVID-19, we plan to start the trial in Q3 2021. Again, we plan to try and avoid the pain and disability associated with Frozen Shoulder by treating early. Post-operative cognitive delirium disorder and dysfunction, a major unmet clinical need occurring in the elderly patient population, most commonly following lengthy anesthesia during hip fracture repair or after CABG. We hope to be able to reduce or prevent this dysfunction. Additionally, our pre-clinical discovery programs include: A program focused on the development of unique, Food and Drug Administration-approved, pharmaceutical-grade oral synthetic cannabidiol analogs to treat pain that is specifically focused on arthritis. This project is run in Israel and Oxford, England. We are working with one of the foremost authorities on Cannabis chemistry and the discoverer of the body's own "cannabinoids", Prof Raphael Mechoulam. To optimize uptake we are working with an expert in cannabinoid drug delivery, Prof Avi Domb in Jerusalem, Israel. The alpha7nAChR program, which aims to develop alpha7nAChR agonists for the treatment of inflammatory diseases, initially ulcerative colitis induced after cessation of smoking. We look forward to the results of our Phase 2b/3 study on Dupuytren's contracture, a disease that impacts a large total addressable market estimated to comprise over 22 million in the US and EU. We believe that if we are able to successfully commercialize this drug, of which there can be no assurance, it has the potential to generate significant revenues for the Company. It is important to note that our business model itself is unique for a biotech company. Almost all our clinical studies to date have been funded in full through grants. While ultimately, we intend to fund some studies internally, we anticipate our operating expenses will remain low relative to our peers. There are many advantages of doing clinical development mostly with academic leaders, both in cost, efficiency and credibility. I'd like to close by telling you why I took the role as CEO and what my personal goal is for the Company. My goal and the goal of the other members of management is to build stockholder value by developing world leading products to solve unmet medical needs. As management and insiders currently own over 50% of the Company, we believe our goals are directly aligned with the stockholders of the Company. Many members of our management team have not taken a salary to date. Future compensation will be conservative, favoring equity over cash."

TODAY'S FREE FLY STORIES

Periodicals
SVF Investment Corp. 3 in talks to bring Mapbox public, Sky News says » 11:18
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SVF Investment Corp. 3

$10.58 /

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SoftBank

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SVFC SVF Investment Corp. 3
$10.58 /

+0.38 (+3.73%)

SFTBY SoftBank
$46.20 /

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SFTBY SoftBank
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$10.58 /

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Technical Analysis
NASDAQ market internals summary » 11:17
04/23/21
04/23
11:17
04/23/21
11:17
$NSD

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SilverCrest Metals price target raised to C$14.50 from C$14 at National Bank » 11:16
04/23/21
04/23
11:16
04/23/21
11:16
SILV

SilverCrest Metals

$8.77 /

-0.05 (-0.57%)

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SILV SilverCrest Metals
$8.77 /

-0.05 (-0.57%)

SILV SilverCrest Metals
$8.77 /

-0.05 (-0.57%)

02/24/21 BMO Capital
SilverCrest Metals resumed with an Outperform at BMO Capital
02/08/21 Stifel
SilverCrest Metals price target lowered to C$15.50 from C$16 at Stifel
02/04/21 National Bank
SilverCrest Metals price target lowered to C$17.25 from C$19 at National Bank
02/04/21 Stifel
SilverCrest Metals upgraded to Buy after Las Chispas study at Stifel
  • 12
    Feb
SILV SilverCrest Metals
$8.77 /

-0.05 (-0.57%)

Technical Analysis
NYSE market internals summary » 11:16
04/23/21
04/23
11:16
04/23/21
11:16
$NYE

NYSE Market Internals

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Recommendations
Marathon Gold price target raised to C$3.50 from C$3.25 at National Bank » 11:15
04/23/21
04/23
11:15
04/23/21
11:15
MGDPF

Marathon Gold

$2.09 /

-0.05 (-2.34%)

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MGDPF Marathon Gold
$2.09 /

-0.05 (-2.34%)

MGDPF Marathon Gold
$2.09 /

-0.05 (-2.34%)

04/06/21 Scotiabank
Marathon Gold price target raised to C$3.50 from C$3.25 at Scotiabank
03/31/21 CIBC
Marathon Gold price target lowered to C$3.75 from C$4 at CIBC
03/31/21 TD Securities
Marathon Gold price target lowered to C$4 from C$4.25 at TD Securities
01/15/21 Raymond James
Marathon Gold price target raised to C$3.50 from C$2.85 at Raymond James
Recommendations
Maverix Metals price target raised to C$7.75 from C$7.50 at National Bank » 11:15
04/23/21
04/23
11:15
04/23/21
11:15
MMX

Maverix Metals

$5.76 /

+0.04 (+0.70%)

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MMX Maverix Metals
$5.76 /

+0.04 (+0.70%)

MMX Maverix Metals
$5.76 /

+0.04 (+0.70%)

04/21/21 Canaccord
Maverix Metals downgraded to Hold from Buy at Canaccord
02/03/21 Raymond James
Maverix Metals price target lowered to C$8.25 from C$8.50 at Raymond James
01/11/21 National Bank
Maverix Metals price target raised to C$8 from C$7.75 at National Bank
09/24/20 National Bank
Maverix Metals price target raised to C$7.75 from C$7.50 at National Bank
  • 29
    May
Recommendations
Franco-Nevada price target raised to C$190 from C$185 at National Bank » 11:14
04/23/21
04/23
11:14
04/23/21
11:14
FNV

Franco-Nevada

$141.99 /

+0.35 (+0.25%)

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FNV Franco-Nevada
$141.99 /

+0.35 (+0.25%)

FNV Franco-Nevada
$141.99 /

+0.35 (+0.25%)

04/20/21 BMO Capital
Franco-Nevada price target raised to C$195 from C$193 at BMO Capital
03/12/21 National Bank
Franco-Nevada price target lowered to C$205 from C$210 at National Bank
03/12/21 Barclays
Franco-Nevada upgraded to Equal Weight from Underweight at Barclays
03/07/21 BMO Capital
Franco-Nevada upgraded to Outperform from Market Perform at BMO Capital
FNV Franco-Nevada
$141.99 /

+0.35 (+0.25%)

FNV Franco-Nevada
$141.99 /

+0.35 (+0.25%)

FNV Franco-Nevada
$141.99 /

+0.35 (+0.25%)

Recommendations
Fortuna Silver Mines price target raised to C$12.50 at National Bank » 11:14
04/23/21
04/23
11:14
04/23/21
11:14
FSM

Fortuna Silver Mines

$7.66 /

-0.02 (-0.26%)

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FSM Fortuna Silver Mines
$7.66 /

-0.02 (-0.26%)

FSM Fortuna Silver Mines
$7.66 /

-0.02 (-0.26%)

04/13/21 BMO Capital
Fortuna Silver Mines price target raised to C$12.50 from C$12.25 at BMO Capital
03/29/21 BMO Capital
Fortuna Silver Mines price target lowered to $12.75 from $13 at BMO Capital
03/11/21 BMO Capital
Fortuna Silver Mines price target raised to C$13 from C$12 at BMO Capital
02/08/21 CIBC
Fortuna Silver Mines price target lowered to C$11.25 from C$11.50 at CIBC
FSM Fortuna Silver Mines
$7.66 /

-0.02 (-0.26%)

FSM Fortuna Silver Mines
$7.66 /

-0.02 (-0.26%)

FSM Fortuna Silver Mines
$7.66 /

-0.02 (-0.26%)

FSM Fortuna Silver Mines
$7.66 /

-0.02 (-0.26%)

Hot Stocks
Teva launches generic version of Casana suppositories » 11:10
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TEVA

Teva

$10.11 /

-0.095 (-0.93%)

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TEVA Teva
$10.11 /

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TEVA Teva
$10.11 /

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TEVA Teva
$10.11 /

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TEVA Teva
$10.11 /

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TEVA Teva
$10.11 /

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TEVA Teva
$10.11 /

-0.095 (-0.93%)

Recommendations
Aya Gold & Silver price target raised to C$9 from C$7.25 at National Bank » 11:07
04/23/21
04/23
11:07
04/23/21
11:07
MYAGF

Aya Gold & Silver

$5.55 /

+ (+0.00%)

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MYAGF Aya Gold & Silver
$5.55 /

+ (+0.00%)

MYAGF Aya Gold & Silver
$5.55 /

+ (+0.00%)

03/30/21 National Bank
Aya Gold & Silver initiated with an Outperform at National Bank
03/29/21 National Bank
Aya Gold & Silver initiated with an Outperform at National Bank
03/29/21 Stifel
Aya Gold & Silver price target raised to C$6 from C$5.80 at Stifel
02/08/21 Stifel
Aya Gold & Silver price target lowered to C$5.80 from C$5.90 at Stifel
Recommendations
Wesdome Gold Mines price target raised to C$12.50 from C$12 at National Bank » 11:07
04/23/21
04/23
11:07
04/23/21
11:07
WDOFF

Wesdome Gold Mines

$7.93 /

-0.2133 (-2.62%)

National Bank analyst Don…

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WDOFF Wesdome Gold Mines
$7.93 /

-0.2133 (-2.62%)

WDOFF Wesdome Gold Mines
$7.93 /

-0.2133 (-2.62%)

03/02/21 Desjardins
Wesdome Gold Mines price target lowered to C$15.75 from C$16.25 at Desjardins
02/02/21 National Bank
Wesdome Gold Mines price target lowered to C$15 from C$16 at National Bank
10/22/20 National Bank
Wesdome Gold Mines price target raised to C$17.50 from C$16.50 at National Bank
09/11/20 National Bank
Wesdome Gold Mines price target raised to C$16.50 from C$16 at National Bank
Recommendations
Yamana Gold price target raised to C$7.25 from C$7 at National Bank » 11:07
04/23/21
04/23
11:07
04/23/21
11:07
AUY

Yamana Gold

$4.78 /

-0.055 (-1.14%)

National Bank analyst…

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AUY Yamana Gold
$4.78 /

-0.055 (-1.14%)

AUY Yamana Gold
$4.78 /

-0.055 (-1.14%)

04/07/21 Berenberg
Yamana Gold price target lowered to 510 GBp from 600 GBp at Berenberg
03/01/21 Berenberg
Yamana Gold price target raised to 600 GBp from 590 GBp at Berenberg
02/16/21 Berenberg
Yamana Gold price target raised to 590 GBp from 560 GBp at Berenberg
02/08/21 Stifel
Yamana Gold price target lowered to C$9.75 from C$10 at Stifel
AUY Yamana Gold
$4.78 /

-0.055 (-1.14%)

AUY Yamana Gold
$4.78 /

-0.055 (-1.14%)

AUY Yamana Gold
$4.78 /

-0.055 (-1.14%)

General news
U.S. new home sales sharply beat estimates » 11:05
04/23/21
04/23
11:05
04/23/21
11:05
$ECON

Economic Data

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    Options
    Coty call volume above normal and directionally bullish » 11:05
    04/23/21
    04/23
    11:05
    04/23/21
    11:05
    COTY

    Coty

    $9.90 /

    +0.705 (+7.67%)

    Bullish option flow…

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    COTY Coty
    $9.90 /

    +0.705 (+7.67%)

    COTY Coty
    $9.90 /

    +0.705 (+7.67%)

    04/16/21 DA Davidson
    Coty price target raised to $9.25 from $6 at DA Davidson
    02/10/21
    Fly Intel: Top five analyst upgrades
    02/10/21 Evercore ISI
    Evercore raises Coty to Outperform, says turnaround 'a question of when,' not if
    02/10/21 Evercore ISI
    Coty upgraded to Outperform from In Line at Evercore ISI
    COTY Coty
    $9.90 /

    +0.705 (+7.67%)

    COTY Coty
    $9.90 /

    +0.705 (+7.67%)

    COTY Coty
    $9.90 /

    +0.705 (+7.67%)

    COTY Coty
    $9.90 /

    +0.705 (+7.67%)

    General news
    FX Action: USD-JPY » 11:05
    04/23/21
    04/23
    11:05
    04/23/21
    11:05
    $ECON

    Economic Data

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      Hot Stocks
      3M says MA MicroGrind wheels found to infringe on German Utility Model » 11:04
      04/23/21
      04/23
      11:04
      04/23/21
      11:04
      MMM

      3M

      $202.32 /

      +1.32 (+0.66%)

      The German District Court…

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      MMM 3M
      $202.32 /

      +1.32 (+0.66%)

      MMM 3M
      $202.32 /

      +1.32 (+0.66%)

      04/13/21 Deutsche Bank
      3M named 'Catalyst Call: Sell Idea' at Deutsche Bank
      04/06/21 Barclays
      3M price target raised to $180 from $163 at Barclays
      03/23/21 Credit Suisse
      3M price target raised to $202 from $197 at Credit Suisse
      02/03/21
      Fly Intel: Top five analyst upgrades
      MMM 3M
      $202.32 /

      +1.32 (+0.66%)

      MMM 3M
      $202.32 /

      +1.32 (+0.66%)

      MMM 3M
      $202.32 /

      +1.32 (+0.66%)

      MMM 3M
      $202.32 /

      +1.32 (+0.66%)

      Recommendations
      OceanaGold price target lowered to C$3 from C$3.25 at National Bank » 11:02
      04/23/21
      04/23
      11:02
      04/23/21
      11:02
      OCANF

      OceanaGold

      $1.86 /

      -0.054 (-2.83%)

      National Bank analyst…

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      OCANF OceanaGold
      $1.86 /

      -0.054 (-2.83%)

      04/06/21 Scotiabank
      OceanaGold price target lowered to C$4.75 from C$5 at Scotiabank
      02/19/21 JPMorgan
      OceanaGold downgraded to Neutral from Overweight at JPMorgan
      02/08/21 CIBC
      OceanaGold price target raised to C$2.85 from C$2.65 at CIBC
      02/08/21 Stifel
      OceanaGold price target lowered to C$4.50 from C$5.50 at Stifel
      Hot Stocks
      Northern Genesis Acquisition reports stockholders approve combination with Lion » 11:02
      04/23/21
      04/23
      11:02
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      NGA

      Northern Genesis Acquisition

      $15.60 /

      +0.445 (+2.94%)

      , LEV

      Lion Electric

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      NGA Northern Genesis Acquisition
      $15.60 /

      +0.445 (+2.94%)

      • 18
        Aug
      NGA Northern Genesis Acquisition
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      Conference/Events
      Goldman Sachs communications tech analyst holds analyst/industry conference call » 10:55
      04/23/21
      04/23
      10:55
      04/23/21
      10:55

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      Recommendations
      New Gold price target lowered to C$3 from C$3.25 at National Bank » 10:53
      04/23/21
      04/23
      10:53
      04/23/21
      10:53
      NGD

      New Gold

      $1.74 /

      +0.01 (+0.58%)

      National Bank analyst…

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      NGD New Gold
      $1.74 /

      +0.01 (+0.58%)

      NGD New Gold
      $1.74 /

      +0.01 (+0.58%)

      02/22/21 Canaccord
      New Gold price target lowered to C$2.75 from C$3.75 at Canaccord
      02/11/21 National Bank
      New Gold price target lowered to C$4 from C$4.25 at National Bank
      02/03/21 CIBC
      New Gold downgraded to Neutral after mine fatality at CIBC
      02/02/21 CIBC
      New Gold downgraded to Neutral from Outperformer at CIBC
      NGD New Gold
      $1.74 /

      +0.01 (+0.58%)

      Recommendations
      Equinox Gold price target lowered to C$15.25 from C$15.50 at National Bank » 10:52
      04/23/21
      04/23
      10:52
      04/23/21
      10:52
      EQX

      Equinox Gold

      $8.59 /

      -0.14 (-1.60%)

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      EQX Equinox Gold
      $8.59 /

      -0.14 (-1.60%)

      EQX Equinox Gold
      $8.59 /

      -0.14 (-1.60%)

      04/08/21 CIBC
      Equinox Gold price target lowered to C$14 from C$19 at CIBC
      03/23/21 BMO Capital
      Equinox Gold price target lowered to C$19.50 from C$20.50 at BMO Capital
      03/05/21 BMO Capital
      Equinox Gold price target raised to C$20.50 from C$20 at BMO Capital
      03/05/21 TD Securities
      Equinox Gold price target lowered to C$20 from C$22 at TD Securities
      EQX Equinox Gold
      $8.59 /

      -0.14 (-1.60%)

      Recommendations
      Eldorado Gold price target lowered to C$18 from C$19 at National Bank » 10:52
      04/23/21
      04/23
      10:52
      04/23/21
      10:52
      EGO

      Eldorado Gold

      $11.15 /

      -0.115 (-1.02%)

      National Bank analyst…

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      EGO Eldorado Gold
      $11.15 /

      -0.115 (-1.02%)

      EGO Eldorado Gold
      $11.15 /

      -0.115 (-1.02%)

      03/09/21 BofA
      Eldorado Gold downgraded to Neutral from Buy at BofA
      02/08/21 CIBC
      Eldorado Gold price target raised to $20 from $16.75 at CIBC
      02/02/21 National Bank
      Eldorado Gold price target lowered to C$20.50 from C$22 at National Bank
      01/19/21 Stifel
      Eldorado Gold price target lowered to C$22 from C$23 at Stifel
      EGO Eldorado Gold
      $11.15 /

      -0.115 (-1.02%)

      EGO Eldorado Gold
      $11.15 /

      -0.115 (-1.02%)

      EGO Eldorado Gold
      $11.15 /

      -0.115 (-1.02%)

      Recommendations
      Dundee Precious Metals price target raised to C$12.50 at National Bank » 10:51
      04/23/21
      04/23
      10:51
      04/23/21
      10:51
      DPMLF

      Dundee Precious Metals

      $7.60 /

      -0.01757 (-0.23%)

      National Bank analyst Don…

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      DPMLF Dundee Precious Metals
      $7.60 /

      -0.01757 (-0.23%)

      DPMLF Dundee Precious Metals
      $7.60 /

      -0.01757 (-0.23%)

      03/31/21 Stifel
      Dundee Precious Metals price target raised to C$13 from C$12.75 at Stifel
      02/24/21 Canaccord
      Dundee Precious Metals price target lowered to C$10.75 at Canaccord
      02/12/21 Scotiabank
      Dundee Precious Metals price target lowered to C$12 from C$13 at Scotiabank
      02/08/21 CIBC
      Dundee Precious Metals price target lowered to C$12.50 from C$14.25 at CIBC
      Recommendations
      Centerra Gold price target raised to C$18.50 from C$17.50 at National Bank » 10:50
      04/23/21
      04/23
      10:50
      04/23/21
      10:50
      CGAU

      Centerra Gold

      $9.33 /

      +0.07 (+0.76%)

      National Bank analyst…

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      CGAU Centerra Gold
      $9.33 /

      +0.07 (+0.76%)

      CGAU Centerra Gold
      $9.33 /

      +0.07 (+0.76%)

      04/21/21 Canaccord
      Centerra Gold downgraded to Speculative Buy from Buy at Canaccord
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      Ford put volume 5x normal including correction » 10:50
      04/23/21
      04/23
      10:50
      04/23/21
      10:50
      F

      Ford

      $12.10 /

      +0.145 (+1.21%)

      Ford put volume 5x normal…

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      F Ford
      $12.10 /

      +0.145 (+1.21%)

      F Ford
      $12.10 /

      +0.145 (+1.21%)

      04/22/21 Deutsche Bank
      Ford named 'Catalyst Call: Buy Idea' at Deutsche Bank
      04/22/21 Wolfe Research
      Wolfe upgrades Ford with $15 target, sees GM-like 'significant re-rating'
      04/22/21 Wolfe Research
      Ford upgraded to Outperform from Peer Perform at Wolfe Research
      04/14/21 Evercore ISI
      Ford price target raised to $13 from $11 at Evercore ISI
      F Ford
      $12.10 /

      +0.145 (+1.21%)

      F Ford
      $12.10 /

      +0.145 (+1.21%)

      F Ford
      $12.10 /

      +0.145 (+1.21%)

      F Ford
      $12.10 /

      +0.145 (+1.21%)

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