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2020-12-01 09:07:42 EARS Auris Medical $1.10 / -0.03 (-2.65%) 09:07 12/01/20 12/01 09:07 12/01/20 09:07	Auris Medical reports in vitro efficacy data from AM-301 Auris Medical Holding announced positive efficacy data from testing AM-301 in vitro. AM-301 is a drug-free nasal spray being developed by the Company's affiliate Altamira Medica for protection against airborne pathogens and allergens. AM-301 was tested for its capability to prevent or mitigate SARS-CoV-2 infection of nasal epithelial cells, which are part of the nasal mucosa and the first barrier against continuously inhaled substances such as pathogens and allergens. The experiment was performed over four days on reconstituted human nasal epithelia, which are frequently used to study the effects of human respiratory viruses. In saline-treated control cultures, Sars-CoV-2 replicated efficiently, resulting in a rapid increase in viral titer. In contrast, daily treatment with AM-301, beginning right before inoculation, showed effective protection against viral infection. 48 hours post-infection, average virus titers were 90.0% lower than those observed in controls. 72 hours and 96 hours post-infection, average virus titers were 99.2 and 99.4% lower, respectively. Even when unbound virus was not removed daily through apical washing, allowing the virus to accumulate in the culture for 4 days, the reduction in viral titer was 92.4% compared to saline-treated controls.

2020-12-01 09:07:42

EARS

Auris Medical

$1.10 / -0.03 (-2.65%)

09:07

12/01/20

12/01

09:07

12/01/20

09:07

Auris Medical reports in vitro efficacy data from AM-301

Auris Medical Holding announced positive efficacy data from testing AM-301 in vitro. AM-301 is a drug-free nasal spray being developed by the Company's affiliate Altamira Medica for protection against airborne pathogens and allergens. AM-301 was tested for its capability to prevent or mitigate SARS-CoV-2 infection of nasal epithelial cells, which are part of the nasal mucosa and the first barrier against continuously inhaled substances such as pathogens and allergens. The experiment was performed over four days on reconstituted human nasal epithelia, which are frequently used to study the effects of human respiratory viruses. In saline-treated control cultures, Sars-CoV-2 replicated efficiently, resulting in a rapid increase in viral titer. In contrast, daily treatment with AM-301, beginning right before inoculation, showed effective protection against viral infection. 48 hours post-infection, average virus titers were 90.0% lower than those observed in controls. 72 hours and 96 hours post-infection, average virus titers were 99.2 and 99.4% lower, respectively. Even when unbound virus was not removed daily through apical washing, allowing the virus to accumulate in the culture for 4 days, the reduction in viral titer was 92.4% compared to saline-treated controls.

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Conference/Events	Roth Capital to hold a webinar » 10:25 01/15/21 01/15 10:25 01/15/21 10:25 NOVA Sunnova Energy $48.02 / -1.63 (-3.28%) Webinar entitled,… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in 9 minutes Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings Syndicate On The Fly Events Options NOVA Sunnova Energy $48.02 / -1.63 (-3.28%) 01/12/21 Sunnova Energy falls -6.7% 01/06/21 Enphase Energy, Sunnova Energy expand partnership to include battery storage 12/16/20 Upstart Power announces investment for residential fuel cell technology 10/14/20 Sunnova Energy expands SunSafe, +SunSafe solar and storage offerings NOVA Sunnova Energy $48.02 / -1.63 (-3.28%) 01/04/21 Goldman Sachs Sunnova Energy price target raised to $60 from $45 at Goldman Sachs 01/04/21 JMP Securities Sunnova Energy price target raised to $66 from $53 at JMP Securities 12/28/20 KeyBanc Sunnova Energy price target raised to $52 from $28 at KeyBanc 12/24/20 Roth Capital Roth Capital calls Generac, Sunnova, Enphase favorite 2021 solar ideas NOVA Sunnova Energy $48.02 / -1.63 (-3.28%) 10/28/20 Sunnova sees FY21 adjusted EBITDA $77M-$83M 10/28/20 Sunnova backs FY20 adjusted EBITDA view $58M-$62M 10/28/20 Sunnova reports Q3 EPS (73c), consensus (15c) 10/28/20 Notable companies reporting after market close 16 Dec 01 Dec 14 Aug 01 Jul NOVA Sunnova Energy $48.02 / -1.63 (-3.28%) 01/09/21 Charged: Apple self-driving EV said to be years away 12/26/20 Charged: Apple's potential EV entry seen as 'Tesla bear case' 12/26/20 Week in review: How Trump's policies moved stocks 12/19/20 Charged: Deutsche sees multiple EV winners, says buy Xpev 00:00 Today Sustainability: Solar 03/15/21 33rd Annual Roth Virtual Conference NOVA Sunnova Energy $48.02 / -1.63 (-3.28%) 10/28/20 Sunnova Energy options imply 20.0% move in share price post-earnings 08/26/20 Eight new option listings on August 26th
Options	Vale call volume above normal and directionally bullish » 10:25 01/15/21 01/15 10:25 01/15/21 10:25 VALE Vale $17.92 / -1.01 (-5.34%) Bullish option flow… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings Periodicals Options VALE Vale $17.92 / -1.01 (-5.34%) 12/24/20 Vale to restart operations at Samarco plant 12/24/20 BHP Group to restart operations at Samarco plant 10/28/20 Vale reports Q3 iron ore fines production 88.7 Mt, up 21.1 Mt vs. Q2 07/29/20 Vale backs 2020 iron ore fines production view of 310-330 Mt VALE Vale $17.92 / -1.01 (-5.34%) 12/14/20 JPMorgan Vale price target raised to $24.50 from $19 at JPMorgan 12/03/20 HSBC Vale price target raised to $17.25 from $14.75 at HSBC 11/25/20 Scotiabank Vale price target raised to $17 from $16 at Scotiabank 10/08/20 Itau BBA Vale downgraded to Market Perform from Outperform at Itau BBA VALE Vale $17.92 / -1.01 (-5.34%) 10/28/20 Vale reports Q3 adjusted EBITDA $6.22B vs $4.6B last year VALE Vale $17.92 / -1.01 (-5.34%) 10/02/20 Vale in talks with Tesla, EV sector over nickel from Canada, Reuters reports 10/02/20 Vale in talks with Tesla, EV sector over nickel from Canada, Reuters reports 10/01/20 Brazil prosecutors seek to re-open $27B suit vs. Vale and BHP, Reuters says VALE Vale $17.92 / -1.01 (-5.34%) 01/11/21 Notable open interest changes for January 11th 12/21/20 Notable open interest changes for December 21st 12/04/20 Vale call volume above normal and directionally bullish 12/03/20 Vale call volume above normal and directionally bullish

Hot Stocks	Wells Fargo no longer offering Covid deferrals, except in home lending, CFO says 10:24 01/15/21 01/15 10:24 01/15/21 10:24 WFC Wells Fargo $32.20 / -2.56 (-7.36%) ShowHide Related Items >><< Company News Street Research Earnings Periodicals On The Fly Events Options WFC Wells Fargo $32.20 / -2.56 (-7.36%) 10:20 Today Wells Fargo CEO sees path to longer-term ROTCE of around 15% 10:15 Today Wells Fargo CEO: Efficiency ratio 'not competitive' 10:09 Today Wells Fargo CEO: Returns significantly below where they should be 10:03 Today Wells Fargo CEO expects 2021 to get off to a slow start WFC Wells Fargo $32.20 / -2.56 (-7.36%) 01/12/21 UBS UBS downgrades Citizens on revenue headwinds, Wells new top pick 01/11/21 UBS Wells Fargo upgraded to Buy from Neutral at UBS 01/07/21 Jefferies Wells Fargo upgraded to Buy with $38 price target at Jefferies 01/07/21 Jefferies Wells Fargo upgraded to Buy from Hold at Jefferies WFC Wells Fargo $32.20 / -2.56 (-7.36%) 08:07 Today Wells Fargo reports Q4 EPS 64c, consensus 60c 01/14/21 Notable companies reporting before tomorrow's open 01/14/21 Notable companies reporting before tomorrow's open 01/14/21 Fly Intel: What to watch in first round of big bank earnings reports WFC Wells Fargo $32.20 / -2.56 (-7.36%) 01/14/21 Wells Fargo close to deal for asset management business, Reuters reports 01/14/21 Wells Fargo in talks to sell asset management unit to buyout firms, Reuters says 12/22/20 Tech companies win as SEC permits direct IPOs for cash raise, Bloomberg says 12/22/20 Wells Fargo satisfied consent order requirements, American Banker reports WFC Wells Fargo $32.20 / -2.56 (-7.36%) 09:02 Today Fly Intel: Pre-market Movers 01/12/21 NIO downgrade, Wells Fargo upgrade among today's top calls on Wall Street 01/06/21 Fly Intel: Pre-market Movers 12/15/20 Fly Intel: Wall Street's top stories for Tuesday 02/24/21 22nd Annual Virtual Financial Services Forum 10:00 Today Wells Fargo - WFC WFC Wells Fargo $32.20 / -2.56 (-7.36%) 01/12/21 Unusually active option classes on open January 12th 11/24/20 Unusual call flow in option market yesterday 11/23/20 Call butterfly sale in Wells Fargo might adjust positions 11/19/20 Notable open interest changes for November 19th
Periodicals	Rigel looks to choke 'storm' that causes Covid patients to die, SFBT says » 10:24 01/15/21 01/15 10:24 01/15/21 10:24 RIGL Rigel Pharmaceuticals $3.80 / -0.015 (-0.39%) Rigel Pharmaceuticals… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings On The Fly Options RIGL Rigel Pharmaceuticals $3.80 / -0.015 (-0.39%) 11/23/20 Rigel Pharmaceuticals, Medison announce Health Canada Aaproval of TAVALISSE 11/17/20 Rigel Pharmaceuticals reaches agreement with FDA on FORWARD study design 10/09/20 Rigel Pharmaceuticals: First patients enrolled in Phase 2 trial of fostamatinib 09/17/20 Rigel Pharmaceuticals starts Phase 2 trial to evaluate safety of fostamatinib RIGL Rigel Pharmaceuticals $3.80 / -0.015 (-0.39%) 11/09/20 Fly Intel: Top five analyst downgrades 11/09/20 JPMorgan Rigel Pharmaceuticals downgraded to Neutral from Overweight at JPMorgan 09/17/20 H.C. Wainwright Rigel expansion into COVID-19 continues with NIH trial, says H.C. Wainwright 09/17/20 BMO Capital Tavalisse in COVID pneumonia a potential catalyst for Rigel, says BMO Capital RIGL Rigel Pharmaceuticals $3.80 / -0.015 (-0.39%) 01/11/21 Rigel Pharmaceuticals sees Q4 revenue approximately $18.4M, consensus $17.81M 11/05/20 Rigel Pharmaceuticals reports Q3 EPS (8c), consensus (12c) 08/04/20 Rigel Pharmaceuticals reports Q2 EPS (10c), consensus (13c) RIGL Rigel Pharmaceuticals $3.80 / -0.015 (-0.39%) 09/17/20 Fly Intel: Pre-market Movers 08/04/20 Fly Intel: After-Hours Movers 07/16/20 Rigel CEO tells Fly own fostamatinib trial in COVID-19 could be next step RIGL Rigel Pharmaceuticals $3.80 / -0.015 (-0.39%) 08/04/20 Rigel Pharmaceuticals options imply 25.1% move in share price post-earnings
Hot Stocks	Wells Fargo CEO sees path to longer-term ROTCE of around 15% 10:20 01/15/21 01/15 10:20 01/15/21 10:20 WFC Wells Fargo $32.36 / -2.4 (-6.90%) ShowHide Related Items >><< Company News Street Research Earnings Periodicals On The Fly Events Options WFC Wells Fargo $32.36 / -2.4 (-6.90%) 10:15 Today Wells Fargo CEO: Efficiency ratio 'not competitive' 10:09 Today Wells Fargo CEO: Returns significantly below where they should be 10:03 Today Wells Fargo CEO expects 2021 to get off to a slow start 08:14 Today Wells Fargo sees expenses of about $53B ex-restructuring charges, business exits WFC Wells Fargo $32.36 / -2.4 (-6.90%) 01/12/21 UBS UBS downgrades Citizens on revenue headwinds, Wells new top pick 01/11/21 UBS Wells Fargo upgraded to Buy from Neutral at UBS 01/07/21 Jefferies Wells Fargo upgraded to Buy with $38 price target at Jefferies 01/07/21 Jefferies Wells Fargo upgraded to Buy from Hold at Jefferies WFC Wells Fargo $32.36 / -2.4 (-6.90%) 08:07 Today Wells Fargo reports Q4 EPS 64c, consensus 60c 01/14/21 Notable companies reporting before tomorrow's open 01/14/21 Notable companies reporting before tomorrow's open 01/14/21 Fly Intel: What to watch in first round of big bank earnings reports WFC Wells Fargo $32.36 / -2.4 (-6.90%) 01/14/21 Wells Fargo close to deal for asset management business, Reuters reports 01/14/21 Wells Fargo in talks to sell asset management unit to buyout firms, Reuters says 12/22/20 Tech companies win as SEC permits direct IPOs for cash raise, Bloomberg says 12/22/20 Wells Fargo satisfied consent order requirements, American Banker reports WFC Wells Fargo $32.36 / -2.4 (-6.90%) 09:02 Today Fly Intel: Pre-market Movers 01/12/21 NIO downgrade, Wells Fargo upgrade among today's top calls on Wall Street 01/06/21 Fly Intel: Pre-market Movers 12/15/20 Fly Intel: Wall Street's top stories for Tuesday 02/24/21 22nd Annual Virtual Financial Services Forum 10:00 Today Wells Fargo - WFC WFC Wells Fargo $32.36 / -2.4 (-6.90%) 01/12/21 Unusually active option classes on open January 12th 11/24/20 Unusual call flow in option market yesterday 11/23/20 Call butterfly sale in Wells Fargo might adjust positions 11/19/20 Notable open interest changes for November 19th
Technical Analysis	NASDAQ market internals summary » 10:17 01/15/21 01/15 10:17 01/15/21 10:17 $NSD NASDAQ Market Internals $0.00 / + (+0.00%) Volume is above average… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Technical Analysis $NSD NASDAQ Market Internals $0.00 / + (+0.00%) 01/14/21 NASDAQ market internals summary 01/14/21 NASDAQ market internals summary 01/14/21 NASDAQ market internals summary 01/14/21 NASDAQ market internals summary
Technical Analysis	NYSE market internals summary » 10:16 01/15/21 01/15 10:16 01/15/21 10:16 $NYE NYSE Market Internals $0.00 / + (+0.00%) Volume is above average… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in 9 minutes Get Free Trial ShowHide Related Items >><< Technical Analysis $NYE NYSE Market Internals $0.00 / + (+0.00%) 01/14/21 NYSE market internals summary 01/14/21 NYSE market internals summary 01/14/21 NYSE market internals summary 01/14/21 NYSE market internals summary

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NTIC
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Northern Technologies International Co. Firm Sponsored Meetings

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MARA
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Marathon Patent Group, Inc. Firm Sponsored Meetings

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FPRX
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Five Prime - FPRX Conference Calls
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2021 NANS Virtual Meeting Conferences

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This week’s upcoming IPOs and secondary offerings

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Mon	QLI X QLI Qilian International IPO Managers: Univest Securities, Loop Capital & Alexander Capital Priced at: $5.00 5M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial MDGS X MDGS Medigus Secondary Managers: Aegis Priced at: $2.30 3.66M Shares O X O Realty Income Spot Secondary Managers: BofA, Morgan Stanley, Wells Fargo & Citi Priced at: $57.05 10.5M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial PSTL X PSTL Postal Realty Trust Spot Secondary Managers: Jefferies, Stifel, BMO Capital & Janney Montgomery Scott Priced at: $15.25 3.25M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial
Tues	ALXO X ALXO ALX Oncology Block Trade Managers: Jefferies Priced at: $82.00 250K Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial IMAB X IMAB I-MAB Block Trade Managers: Jefferies Priced at: $53.00 642K Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial AFRM X AFRM Affirm IPO Managers: Morgan Stanley, Goldman Sachs & Allen & Co., RBC Capital, Credit Suisse, Barclays, Truist, SIEB, Deutsche Bank Priced at: $49.00 24.6M Shares Special Comments Ratings Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial MSGM X MSGM Motorsport Games IPO Managers: Canaccord & Benchmark Priced at: $20.00 3M Shares Special Comments Ratings Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial HCDI X HCDI Harbor Custom Development Secondary Managers: ThinkEquity Priced at: $3.00 8M Shares ZM X ZM Zoom Video Secondary Managers: JPMorgan Priced at: $340.00 5.1M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial AFMD X AFMD Affimed N.V. Spot Secondary Managers: Jefferies, SVB Leerink & Credit Suisse Priced at: $6.00 16.667M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial RILY X RILY B. Riley Financial Spot Secondary Managers: B. Riley Securities Priced at: $46.00 1.229M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial
Wed	POSH X POSH Poshmark IPO Managers: Morgan Stanley, Goldman Sachs & Barclays, Stifel, William Blair, Raymond James, Cowen, JMP Securities Priced at: $42.00 6.6M Shares Special Comments Ratings Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial WOOF X WOOF Petco IPO Managers: Goldman Sachs & BofA, Citi, Evercore ISI, Credit Suisse, UBS, Wells Fargo, Baird, Guggenheim, AmeriVet, CL King, R. Seelaus, Ramirez, SIEB Priced at: $18.00 48M Shares Special Comments Ratings Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial LMND X LMND Lemonade Secondary Managers: Goldman Sachs, Morgan Stanley, Allen & Co. & Barclays Priced at: $165.00 4.524M Shares Special Comments Ratings Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial PRVB X PRVB Provention Bio Secondary Managers: SVB Leerink & Cantor Fitzgerald Priced at: $16.00 6.25M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial RPAY X RPAY Repay Holdings Secondary Managers: Credit Suisse & Barclays, Citi, Truist Priced at: $24.00 5.43M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial VNT X VNT Vontier Secondary Managers: Goldman Sachs, Citi & Evercore ISI, JPMorgan, Morgan Stanley, Credit Suisse, UBS, Baird Priced at: $33.50 33.507M Shares ALDX X ALDX Aldeyra Spot Secondary Managers: Jefferies & SVB Leerink Priced at: $9.50 6.842M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial EVOK X EVOK Evoke Pharma Spot Secondary Managers: Laidlaw Priced at: $2.50 5M Shares
Thurs	DRVN X DRVN Driven Brands IPO Managers: Morgan Stanley, BofA, Goldman Sachs, JPMorgan & Barclays, Credit Suisse, Baird, Piper Sandler, William Blair Priced at: $22.00 31.8M Shares Special Comments Ratings Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial KUKE X KUKE Kuke Music IPO Managers: Deutsche Bank, Tigress Financial, AMTD & China International, Valuable Capital Priced at: $10.00 5M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial PLTK X PLTK Playtika IPO Managers: Morgan Stanley, Credit Suisse, Citi, Goldman Sachs, UBS & BofA, Baird, Cowen, Stifel, Wedbush Priced at: $27.00 69.5M Shares Special Comments Ratings Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial AMWL X AMWL Amwell Secondary Managers: Morgan Stanley, Goldman Sachs, Piper Sandler & UBS, Credit Suisse, Cowen, Berenberg Priced at: $27.50 11.281M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial ITP X ITP IT Tech Packaging Secondary Managers: Maxim Priced at: $.55 26.182M Shares EAF X EAF GrafTech Spot Secondary Managers: Morgan Stanley Priced at: $10.90 20M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial LTRN X LTRN Lantern Pharma Spot Secondary Managers: ThinkEquity Priced at: $14.00 4.28M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial
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Auris Medical reports in vitro efficacy data from AM-301

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