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RZLT

Rezolute

$18.26 /

+ (+0.00%)

08:09
12/03/20
12/03
08:09
12/03/20
08:09

Rezolute announces FDA clearance of IND application for RZ402

Rezolute announced that the U.S. Food and Drug Administration has cleared an Investigational New Drug application for RZ402, an orally available plasma kallikrein inhibitor, which is in development for the treatment of diabetic macular edema. The Company expects to initiate a Phase 1 first-in-human clinical study with RZ402 in the first quarter of 2021. RZ402, by inhibiting the formation of kallikrein, blocks the pro-inflammatory, pro-coagulant, and fluid-leakage cascade which is triggered by up-activation of the contact activation system in the setting of DME and other vascular-mediated diseases. As a result, it has been shown to reduce retinal inflammation and retinal vascular leakage of DME by more than 80% in both preventative and treatment models in rodents. Preclinical studies have also shown an excellent safety profile for RZ402 in both single- and repeat-dose settings at a range of doses. These data, taken together with oral bioavailability and exposure-time profile in canines and non-human primates showing target concentrations are achieved at clinically relevant oral doses, demonstrate the potential of RZ402 as a once-daily oral treatment option for DME.

TODAY'S FREE FLY STORIES

Downgrade
DBV Technologies downgraded to Sell from Hold at Societe Generale » 05:25
01/22/21
01/22
05:25
01/22/21
05:25
DBVT

DBV Technologies

$6.51 /

+0.02 (+0.31%)

Societe Generale analyst…

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DBVT DBV Technologies
$6.51 /

+0.02 (+0.31%)

DBVT DBV Technologies
$6.51 /

+0.02 (+0.31%)

01/18/21 Goldman Sachs
DBV Technologies price target raised to $7 from $4 at Goldman Sachs
01/15/21 Citi
DBV Technologies price target raised to $8 from $4 at Citi
01/15/21 H.C. Wainwright
DBV now has 'clear developmental path,' says H.C. Wainwright
11/02/20 Societe Generale
DBV Technologies upgraded to Hold on improved visibility at Societe Generale
DBVT DBV Technologies
$6.51 /

+0.02 (+0.31%)

  • 30
    Jan
DBVT DBV Technologies
$6.51 /

+0.02 (+0.31%)

Initiation
Sage Group initiated with a Buy at Peel Hunt » 05:24
01/22/21
01/22
05:24
01/22/21
05:24
SGPYY

Sage Group

$0.00 /

+ (+0.00%)

Peel Hunt analyst Damindu…

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SGPYY Sage Group
$0.00 /

+ (+0.00%)

SGPYY Sage Group
$0.00 /

+ (+0.00%)

01/11/21 Canaccord
Sage Group price target lowered to 680 GBp from 700 GBp at Canaccord
12/10/20 Morgan Stanley
Sage Group upgraded to Equal Weight from Underweight at Morgan Stanley
11/25/20 JPMorgan
Sage Group price target lowered to 560 GBp from 600 GBp at JPMorgan
11/24/20 UBS
Sage Group price target lowered to 550 GBp from 610 GBp at UBS
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Gerresheimer downgraded to Hold from Buy at Pareto » 05:22
01/22/21
01/22
05:22
01/22/21
05:22
GRRMF

Gerresheimer

$0.00 /

+ (+0.00%)

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GRRMF Gerresheimer
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07/29/20 Berenberg
Gerresheimer price target raised to EUR 115 from EUR 75 at Berenberg
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Siltronic downgraded to Neutral from Buy at Oddo BHF » 05:21
01/22/21
01/22
05:21
01/22/21
05:21
SSLLF

Siltronic

$0.00 /

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SSLLF Siltronic
$0.00 /

+ (+0.00%)

01/12/21 Deutsche Bank
Siltronic price target raised to EUR 150 from EUR 135 at Deutsche Bank
12/11/20 Jefferies
Siltronic downgraded to Hold from Buy at Jefferies
12/04/20 UBS
Siltronic price target raised to EUR 125 from EUR 85 at UBS
12/02/20 Berenberg
Siltronic price target raised to EUR 125 from EUR 85 at Berenberg
Upgrade
Carl Zeiss Meditec upgraded to Hold from Sell at DZ Bank » 05:20
01/22/21
01/22
05:20
01/22/21
05:20
CZMWY

Carl Zeiss Meditec

$0.00 /

+ (+0.00%)

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CZMWY Carl Zeiss Meditec
$0.00 /

+ (+0.00%)

CZMWY Carl Zeiss Meditec
$0.00 /

+ (+0.00%)

01/20/21 Berenberg
Carl Zeiss Meditec price target raised to EUR 127 from EUR 87 at Berenberg
01/20/21 Deutsche Bank
Carl Zeiss Meditec price target raised to EUR 140 from EUR 120 at Deutsche Bank
11/02/20 Deutsche Bank
Carl Zeiss Meditec price target raised to EUR 120 from EUR 110 at Deutsche Bank
10/23/20 UBS
Carl Zeiss Meditec downgraded to Neutral from Buy at UBS
Upgrade
Ericsson upgraded to Buy from Hold at Nordea » 05:19
01/22/21
01/22
05:19
01/22/21
05:19
ERIC

Ericsson

$11.77 /

-0.08 (-0.68%)

Nordea analyst Sami…

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ERIC Ericsson
$11.77 /

-0.08 (-0.68%)

ERIC Ericsson
$11.77 /

-0.08 (-0.68%)

01/14/21 Barclays
Ericsson price target lowered to SEK 120 from SEK 125 at Barclays
11/20/20 UBS
Ericsson price target raised to SEK 102 from SEK 86 at UBS
11/12/20 Societe Generale
Ericsson upgraded to Buy from Hold at Societe Generale
10/22/20 Barclays
Ericsson price target raised to SEK 125 from SEK 110 at Barclays
ERIC Ericsson
$11.77 /

-0.08 (-0.68%)

ERIC Ericsson
$11.77 /

-0.08 (-0.68%)

ERIC Ericsson
$11.77 /

-0.08 (-0.68%)

Downgrade
Syrah Resources downgraded to Neutral from Outperform at Credit Suisse » 05:18
01/22/21
01/22
05:18
01/22/21
05:18
SYAAF

Syrah Resources

$0.00 /

+ (+0.00%)

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Air France-KLM downgraded to Reduce from Hold at Kepler Cheuvreux » 05:18
01/22/21
01/22
05:18
01/22/21
05:18
AFLYY

Air France-KLM

$0.00 /

+ (+0.00%)

Kepler Cheuvreux analyst…

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AFLYY Air France-KLM
$0.00 /

+ (+0.00%)

AFLYY Air France-KLM
$0.00 /

+ (+0.00%)

01/20/21 Barclays
Air France-KLM price target raised to EUR 5.10 from EUR 2.70 at Barclays
12/04/20 Deutsche Bank
Air France-KLM price target raised to EUR 3.50 from EUR 2.10 at Deutsche Bank
12/01/20 UBS
Air France-KLM price target raised to EUR 4.45 from EUR 3.35 at UBS
11/12/20 Kepler Cheuvreux
Air France-KLM upgraded to Hold from Reduce at Kepler Cheuvreux
AFLYY Air France-KLM
$0.00 /

+ (+0.00%)

AFLYY Air France-KLM
$0.00 /

+ (+0.00%)

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Alstom downgraded to Hold from Buy at Kepler Cheuvreux » 05:17
01/22/21
01/22
05:17
01/22/21
05:17
ALSMY

Alstom

$0.00 /

+ (+0.00%)

Kepler Cheuvreux analyst…

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ALSMY Alstom
$0.00 /

+ (+0.00%)

ALSMY Alstom
$0.00 /

+ (+0.00%)

01/20/21 Jefferies
Alstom upgraded to Buy from Hold at Jefferies
01/12/21 Deutsche Bank
Alstom price target raised to EUR 47 from EUR 45 at Deutsche Bank
12/11/20 Credit Suisse
Alstom upgraded to Outperform from Neutral at Credit Suisse
12/08/20 Morgan Stanley
Alstom price target raised to EUR 55 from EUR 51 at Morgan Stanley
ALSMY Alstom
$0.00 /

+ (+0.00%)

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IAG downgraded to Reduce from Hold at Kepler Cheuvreux » 05:17
01/22/21
01/22
05:17
01/22/21
05:17
ICAGY

IAG

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ICAGY IAG
$0.00 /

+ (+0.00%)

ICAGY IAG
$0.00 /

+ (+0.00%)

01/20/21 Barclays
IAG price target raised to 175 GBp from 120 GBp at Barclays
12/31/20
Fly Intel: Top five analyst calls
12/31/20 Citi
IAG upgraded to Buy from Neutral at Citi
12/04/20 Deutsche Bank
IAG price target raised to 220 GBp from 175 GBp at Deutsche Bank
ICAGY IAG
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Upgrade
Adient upgraded to Neutral from Underweight at JPMorgan » 05:16
01/22/21
01/22
05:16
01/22/21
05:16
ADNT

Adient

$35.26 /

-0.71 (-1.97%)

JPMorgan analyst Ryan…

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ADNT Adient
$35.26 /

-0.71 (-1.97%)

ADNT Adient
$35.26 /

-0.71 (-1.97%)

01/20/21 Deutsche Bank
Adient price target raised to $43 from $37 at Deutsche Bank
12/17/20 Barclays
Adient price target raised to $45 from $37 at Barclays
12/16/20 KeyBanc
Adient price target raised to $43 from $36 at KeyBanc
12/02/20 Deutsche Bank
Adient price target raised to $37 from $27 at Deutsche Bank
ADNT Adient
$35.26 /

-0.71 (-1.97%)

Downgrade
Gentherm downgraded to Underweight from Neutral at JPMorgan » 05:16
01/22/21
01/22
05:16
01/22/21
05:16
THRM

Gentherm

$70.38 /

-0.6 (-0.85%)

JPMorgan analyst Ryan…

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THRM Gentherm
$70.38 /

-0.6 (-0.85%)

THRM Gentherm
$70.38 /

-0.6 (-0.85%)

12/23/20 Barrington
Gentherm double downgraded to Underperform at Barrington following rally
12/23/20 Barrington
Gentherm downgraded to Underperform from Outperform at Barrington
10/30/20 Roth Capital
Gentherm price target raised to $53 from $44 at Roth Capital
10/22/20 JPMorgan
Gentherm price target raised to $48 from $43 at JPMorgan
THRM Gentherm
$70.38 /

-0.6 (-0.85%)

Upgrade
Lear upgraded to Overweight from Neutral at JPMorgan » 05:16
01/22/21
01/22
05:16
01/22/21
05:16
LEA

Lear

$168.15 /

+0.79 (+0.47%)

JPMorgan analyst Ryan…

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LEA Lear
$168.15 /

+0.79 (+0.47%)

LEA Lear
$168.15 /

+0.79 (+0.47%)

01/20/21 Deutsche Bank
Lear price target raised to $165 from $150 at Deutsche Bank
01/08/21 Guggenheim
Lear downgraded to Neutral from Buy at Guggenheim
12/17/20 Barclays
Lear upgraded to Overweight from Equal Weight at Barclays
12/16/20 Argus
Lear upgraded to Buy at Argus on high expected demand following COVID
LEA Lear
$168.15 /

+0.79 (+0.47%)

LEA Lear
$168.15 /

+0.79 (+0.47%)

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Visteon downgraded to Underweight from Neutral at JPMorgan » 05:16
01/22/21
01/22
05:16
01/22/21
05:16
VC

Visteon

$142.17 /

+0.6 (+0.42%)

JPMorgan analyst Ryan…

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VC Visteon
$142.17 /

+0.6 (+0.42%)

VC Visteon
$142.17 /

+0.6 (+0.42%)

01/20/21 Deutsche Bank
Visteon price target raised to $166 from $105 at Deutsche Bank
12/17/20 Barclays
Visteon price target raised to $150 from $101 at Barclays
11/19/20 Baird
Visteon price target raised to $130 from $105 at Baird
11/03/20 Goldman Sachs
Visteon upgraded to Neutral from Sell at Goldman Sachs
VC Visteon
$142.17 /

+0.6 (+0.42%)

Downgrade
Aptiv downgraded to Neutral from Overweight at JPMorgan » 05:15
01/22/21
01/22
05:15
01/22/21
05:15
APTV

Aptiv

$143.95 /

-1.16 (-0.80%)

JPMorgan analyst Ryan…

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APTV Aptiv
$143.95 /

-1.16 (-0.80%)

01/20/21 Deutsche Bank
Aptiv price target raised to $160 from $120 at Deutsche Bank
12/22/20 Citi
Citi 'very skeptical' of Apple car, says Tesla most direct competitor
12/17/20 Barclays
Aptiv price target raised to $145 from $112 at Barclays
12/16/20 Argus
Aptiv initiated with a Buy at Argus on 'attractive valuation'
APTV Aptiv
$143.95 /

-1.16 (-0.80%)

  • 10
    Jun
APTV Aptiv
$143.95 /

-1.16 (-0.80%)

Downgrade
TGS-NOPEC downgraded to Sell from Neutral at UBS » 05:15
01/22/21
01/22
05:15
01/22/21
05:15
TGSGY

TGS-NOPEC

$0.00 /

+ (+0.00%)

UBS analyst Amy Wong…

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TGSGY TGS-NOPEC
$0.00 /

+ (+0.00%)

10/09/20 UBS
TGS-NOPEC price target lowered to NOK 135 from NOK 145 at UBS
10/09/20 DNB Markets
TGS-NOPEC downgraded to Sell from Hold at DNB Markets
10/09/20 Danske Bank
TGS-NOPEC downgraded to Hold from Buy at Danske Bank
08/19/20 Fearnley
TGS-NOPEC downgraded to Sell from Buy at Fearnley
Downgrade
Bunzl downgraded to Equal Weight from Overweight at Barclays » 05:14
01/22/21
01/22
05:14
01/22/21
05:14
BZLFF

Bunzl

$0.00 /

+ (+0.00%)

Barclays analyst James…

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Vifor Pharma downgraded to Sell from Neutral at UBS » 05:13
01/22/21
01/22
05:13
01/22/21
05:13
GNHAF

Vifor Pharma

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+

UBS analyst Laura…

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GNHAF Vifor Pharma
/

+

GNHAF Vifor Pharma
/

+

05:13 Today UBS
Vifor Pharma downgraded to Sell from Neutral at UBS
01/04/21 JPMorgan
Vifor Pharma downgraded to Underweight from Neutral at JPMorgan
10/22/20 Credit Suisse
Vifor Pharma price target lowered to CHF 149 from CHF 152 at Credit Suisse
10/21/20 JPMorgan
Vifor Pharma price target lowered to CHF 130 from CHF 175 at JPMorgan
Downgrade
Vifor Pharma downgraded to Sell from Neutral at UBS » 05:13
01/22/21
01/22
05:13
01/22/21
05:13
GNHAF

Vifor Pharma

$0.00 /

+ (+0.00%)

UBS analyst Laura…

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GNHAF Vifor Pharma
$0.00 /

+ (+0.00%)

GNHAF Vifor Pharma
$0.00 /

+ (+0.00%)

01/04/21 JPMorgan
Vifor Pharma downgraded to Underweight from Neutral at JPMorgan
10/22/20 Credit Suisse
Vifor Pharma price target lowered to CHF 149 from CHF 152 at Credit Suisse
10/21/20 JPMorgan
Vifor Pharma price target lowered to CHF 130 from CHF 175 at JPMorgan
10/21/20 UBS
Vifor Pharma price target lowered to CHF 129 from CHF 142 at UBS
Earnings
Chemung Financial reports Q4 EPS $1.11, consensus $1.02 » 05:11
01/22/21
01/22
05:11
01/22/21
05:11
CHMG

Chemung Financial

$33.76 /

-1.16 (-3.32%)

Reports Q4 net…

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CHMG Chemung Financial
$33.76 /

-1.16 (-3.32%)

CHMG Chemung Financial
$33.76 /

-1.16 (-3.32%)

10/22/20 DA Davidson
Chemung Financial downgraded to Neutral from Buy at DA Davidson
03/09/20 DA Davidson
Chemung Financial upgraded to Buy from Neutral at DA Davidson
CHMG Chemung Financial
$33.76 /

-1.16 (-3.32%)

Downgrade
Sage Therapeutics downgraded to Market Perform from Outperform at BMO Capital » 05:08
01/22/21
01/22
05:08
01/22/21
05:08
SAGE

Sage Therapeutics

$92.45 /

+1.19 (+1.30%)

BMO Capital analyst Gary…

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SAGE Sage Therapeutics
$92.45 /

+1.19 (+1.30%)

SAGE Sage Therapeutics
$92.45 /

+1.19 (+1.30%)

01/19/21 Wedbush
Sage Therapeutics price target raised to $98 from $83 at Wedbush
01/04/21
Sage Therapeutics downgraded to Sector Perform at RBC Capital on valuation
01/04/21 Guggenheim
Sage Therapeutics upgraded to Buy from Neutral at Guggenheim
01/04/21 RBC Capital
Sage Therapeutics downgraded to Sector Perform from Outperform at RBC Capital
SAGE Sage Therapeutics
$92.45 /

+1.19 (+1.30%)

SAGE Sage Therapeutics
$92.45 /

+1.19 (+1.30%)

Downgrade
Regis downgraded to Hold from Buy at Jefferies » 05:07
01/22/21
01/22
05:07
01/22/21
05:07
RGS

Regis

$9.25 /

+0.195 (+2.15%)

Jefferies analyst…

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RGS Regis
$9.25 /

+0.195 (+2.15%)

RGS Regis
$9.25 /

+0.195 (+2.15%)

10/30/20 B. Riley Securities
Regis price target raised to $160 from $155 at B. Riley Securities
10/22/20 Loop Capital
Regis downgraded to Hold from Buy at Loop Capital
10/22/20 Loop Capital
Regis downgraded to Hold from Buy at Loop Capital
06/19/20 Loop Capital
Regis price target lowered to $15 from $21 at Loop Capital
RGS Regis
$9.25 /

+0.195 (+2.15%)

RGS Regis
$9.25 /

+0.195 (+2.15%)

RGS Regis
$9.25 /

+0.195 (+2.15%)

Upgrade
Seagate upgraded to Buy from Hold at Summit Insights » 05:07
01/22/21
01/22
05:07
01/22/21
05:07
STX

Seagate

$63.00 /

+1.57 (+2.56%)

Summit Insights analyst…

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STX Seagate
$63.00 /

+1.57 (+2.56%)

STX Seagate
$63.00 /

+1.57 (+2.56%)

05:04 Today Benchmark
Seagate price target raised to $70 from $60 at Benchmark
01/21/21 Barclays
Seagate price target raised to $60 from $41 at Barclays
01/20/21 Wedbush
Seagate price target raised to $56 from $47 at Wedbush
01/19/21 Northland
Seagate price target raised to $72 from $65 at Northland
STX Seagate
$63.00 /

+1.57 (+2.56%)

STX Seagate
$63.00 /

+1.57 (+2.56%)

STX Seagate
$63.00 /

+1.57 (+2.56%)

Downgrade
CSX downgraded to Hold from Buy at Stifel » 05:06
01/22/21
01/22
05:06
01/22/21
05:06
CSX

CSX

$91.61 /

-1.6101 (-1.73%)

Stifel analyst David Ross…

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CSX CSX
$91.61 /

-1.6101 (-1.73%)

CSX CSX
$91.61 /

-1.6101 (-1.73%)

01/20/21 Susquehanna
Railroad recovery expected to continue in 2021, says Susquehanna
01/11/21 Citi
CSX price target raised to $105 from $87 at Citi
12/10/20 Morgan Stanley
Morgan Stanley downgrades CSX to Underweight with bar raised too high
12/10/20 Morgan Stanley
CSX downgraded to Underweight from Equal Weight at Morgan Stanley
CSX CSX
$91.61 /

-1.6101 (-1.73%)

CSX CSX
$91.61 /

-1.6101 (-1.73%)

CSX CSX
$91.61 /

-1.6101 (-1.73%)

Upgrade
PacWest Bancorp upgraded to Outperform from Market Perform at Keefe Bruyette » 05:05
01/22/21
01/22
05:05
01/22/21
05:05
PACW

PacWest Bancorp

$30.33 /

+0.345 (+1.15%)

Keefe Bruyette analyst…

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PACW PacWest Bancorp
$30.33 /

+0.345 (+1.15%)

01/12/21
Fly Intel: Top five analyst initiations
01/12/21 Piper Sandler
PacWest Bancorp assumed with an Overweight at Piper Sandler
01/04/21 Wells Fargo
PacWest Bancorp upgraded to Overweight from Equal Weight at Wells Fargo
12/15/20 Truist
Truist raises price targets on select regional banks
PACW PacWest Bancorp
$30.33 /

+0.345 (+1.15%)

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