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BCRX

BioCryst

$8.30 /

-0.31 (-3.60%)

07:10
12/22/20
12/22
07:10
12/22/20
07:10

BioCryst says data shows galidesivir was safe, generally well tolerated

BioCryst Pharmaceuticals announced that data from part 1 of a clinical trial of its broad-spectrum antiviral, galidesivir, showed that galidesivir was safe and generally well tolerated in patients infected with SARS-CoV-2, the virus that causes COVID-19. The trial was not designed or sized to demonstrate clinical efficacy and no clinical efficacy benefit with galidesivir treatment compared to placebo treatment was observed in the trial. Based on the company's ongoing discussions with the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, a major funding partner for the program, BioCryst expects NIAID to continue their support for the development of galidesivir with a focus on biodefense threats, such as Marburg virus disease, and to discontinue the pursuit of a COVID-19 indication for galidesivir. BioCryst is engaged in ongoing discussions with NIAID to define specific further galidesivir studies that NIAID would support. Part 1 of the trial enrolled 24 hospitalized adults diagnosed with moderate to severe COVID-19 confirmed by PCR. Three cohorts of eight patients were randomized to receive intravenous galidesivir or placebo every 12 hours for seven days. Each dosing regimen began with a single 10 mg/kg or 20 mg/kg loading dose, followed by a maintenance dose of 2 mg/kg or 5 mg/kg administered twice daily. The three dosing regimens evaluated were 10 mg/kg then 2 mg/kg, 10 mg/kg then 5 mg/kg and 20 mg/kg then 5 mg/kg. The trial was conducted in Brazil under a U.S. investigational new drug application. The protocol also was approved by the Agencia Nacional de Vigilancia Sanitaria (ANVISA) and the Brazilian National Ethics Committee. The primary objective of part 1 of the dose-ranging study was to evaluate the safety of galidesivir. No safety signals were identified, and all three dose levels were equally safe. Secondary objectives were to evaluate the effect of galidesivir on the clinical course of COVID-19 and on SARS-CoV-2 infection in the respiratory tract. Galidesivir treatment was associated with a more rapid decline in viral RNA levels in the respiratory tract in an apparent dose-dependent manner. A separate study of galidesivir in a COVID-19 animal model showed that early administration of galidesivir reduced SARS-CoV-2 viral burden in lung tissue and was associated with a significant reduction in damage to lung tissue, compared to vehicle control treated animals. These results suggest that early antiviral treatment of SARS-CoV-2 infection may protect against developing severe COVID-19 lung disease.

  • 28

    May

BCRX BioCryst
$8.30 /

-0.31 (-3.60%)

12/07/20 H.C. Wainwright
BioCryst price target raised to $14 from $13 at H.C. Wainwright
12/04/20 Piper Sandler
BioCryst receives on-time approval with 'clean' label, says Piper Sandler
11/23/20 Evercore ISI
BioCryst initiated with an Outperform at Evercore ISI
11/23/20 Evercore ISI
BioCryst initiated with an Outperform at Evercore ISI

TODAY'S FREE FLY STORIES

Recommendations
Mirriad Advertising price target lowered to 44 GBp from 58 GBp at Canaccord » 10:51
07/29/21
07/29
10:51
07/29/21
10:51
MMDDF

Mirriad Advertising

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Recommendations
Yangarra Resources price target lowered to C$1.90 from C$2.50 at Canaccord » 10:50
07/29/21
07/29
10:50
07/29/21
10:50
YGRAF

Yangarra Resources

$1.07 /

-0.0449 (-4.03%)

Canaccord analyst Anthony…

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YGRAF Yangarra Resources
$1.07 /

-0.0449 (-4.03%)

06/17/21 National Bank
Yangarra Resources price target raised to C$2 from C$1.50 at National Bank
03/10/21 CIBC
Yangarra Resources upgraded to Outperformer from Neutral at CIBC
03/08/21 CIBC
Yangarra Resources price target raised to C$1.25 from C$0.80 at CIBC
02/19/21 National Bank
Yangarra Resources price target raised to C$1.50 from C$1.00 at National Bank
Recommendations
Toromont Industries price target raised to C$115 from C$111 at Canaccord » 10:50
07/29/21
07/29
10:50
07/29/21
10:50
TMTNF

Toromont Industries

$83.09 /

+2.77 (+3.45%)

Canaccord analyst Yuri…

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TMTNF Toromont Industries
$83.09 /

+2.77 (+3.45%)

TMTNF Toromont Industries
$83.09 /

+2.77 (+3.45%)

06/10/21 National Bank
Toromont Industries price target raised to C$125 from C$108 at National Bank
05/24/21 BMO Capital
Toromont Industries upgraded to Outperform from Market Perform at BMO Capital
05/24/21 BMO Capital
Finning International downgraded to Market Perform from Outperform at BMO Capital
05/06/21 CIBC
Toromont Industries price target raised to C$106 from C$100 at CIBC
Syndicate
Robinhood indicated to open at $39.25, IPO priced at $38  10:50
07/29/21
07/29
10:50
07/29/21
10:50
HOOD

Robinhood

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09:53 Today
Fly Intel: Top five analyst initiations
06:27 Today Atlantic Equities
Robinhood initiated with an Overweight at Atlantic Equities
  • 29
    Jul
HOOD Robinhood
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HOOD Robinhood
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Recommendations
Real Matters price target lowered to C$22 from C$25 at Canaccord » 10:49
07/29/21
07/29
10:49
07/29/21
10:49
RLLMF

Real Matters

$10.60 /

-1.4234 (-11.84%)

Canaccord analyst Robert…

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RLLMF Real Matters
$10.60 /

-1.4234 (-11.84%)

10:42 Today National Bank
Real Matters downgraded to Sector Perform from Outperform at National Bank
08:56 Today TD Securities
Real Matters downgraded to Hold from Buy at TD Securities
04/29/21 Scotiabank
Real Matters price target lowered to C$22 from C$24 at Scotiabank
04/29/21 TD Securities
Real Matters price target lowered to C$22 from C$30 at TD Securities
Recommendations
CGI Inc. price target raised to C$125 from C$120 at Canaccord » 10:48
07/29/21
07/29
10:48
07/29/21
10:48
GIB

CGI Inc.

$89.56 /

-0.36 (-0.40%)

Canaccord analyst Robert…

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GIB CGI Inc.
$89.56 /

-0.36 (-0.40%)

GIB CGI Inc.
$89.56 /

-0.36 (-0.40%)

06:43 Today RBC Capital
CGI Inc. price target raised to C$125 from C$120 at RBC Capital
07/23/21 BMO Capital
CGI Inc. price target raised to C$128 from C$121 at BMO Capital
07/22/21 National Bank
CGI Inc. price target raised to C$135 from C$120 at National Bank
07/19/21 Scotiabank
CGI Inc. price target raised to C$124 from C$114 at Scotiabank
GIB CGI Inc.
$89.56 /

-0.36 (-0.40%)

Syndicate
Robinhood indicated to open at $39.50, IPO priced at $38  10:48
07/29/21
07/29
10:48
07/29/21
10:48
HOOD

Robinhood

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HOOD Robinhood
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09:53 Today
Fly Intel: Top five analyst initiations
06:27 Today Atlantic Equities
Robinhood initiated with an Overweight at Atlantic Equities
  • 29
    Jul
HOOD Robinhood
/

+

HOOD Robinhood
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Conference/Events
Alpha Healthcare Acquisition participates in a conference call with Benchmark » 10:46
07/29/21
07/29
10:46
07/29/21
10:46
AHAC

Alpha Healthcare Acquisition

$9.97 /

+0.01 (+0.10%)

Research Analyst Jackson…

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AHAC Alpha Healthcare Acquisition
$9.97 /

+0.01 (+0.10%)

AHAC Alpha Healthcare Acquisition
$9.97 /

+0.01 (+0.10%)

07/20/21 Benchmark
Alpha Healthcare Acquisition initiated with a Buy at Benchmark
04/09/21 Lake Street
Lake Street starts Alpha Healthcare Acquisition at Buy ahead of Humacyte closing
04/09/21 Lake Street
Alpha Healthcare Acquisition initiated with a Buy at Lake Street
AHAC Alpha Healthcare Acquisition
$9.97 /

+0.01 (+0.10%)

AHAC Alpha Healthcare Acquisition
$9.97 /

+0.01 (+0.10%)

On The Fly
Fly Intel: What to watch in Pinterest's earnings report » 10:46
07/29/21
07/29
10:46
07/29/21
10:46
PINS

Pinterest

$74.08 /

-2.66 (-3.47%)

, SNAP

Snap

$75.90 /

-0.35 (-0.46%)

, TWTR

Twitter

$70.74 /

+0.8 (+1.14%)

Pinterest (PINS) is…

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PINS Pinterest
$74.08 /

-2.66 (-3.47%)

SNAP Snap
$75.90 /

-0.35 (-0.46%)

TWTR Twitter
$70.74 /

+0.8 (+1.14%)

PINS Pinterest
$74.08 /

-2.66 (-3.47%)

07/23/21 Morgan Stanley
Snap price target raised to $85 from $75 at Morgan Stanley
05/10/21 Arete
Pinterest initiated with a Buy at Arete
05/10/21 Citi
Pinterest price target lowered to $65 from $85 at Citi
04/30/21 MKM Partners
Twitter price target lowered to $83 from $95 at MKM Partners
SNAP Snap
$75.90 /

-0.35 (-0.46%)

08:04 Today Wells Fargo
Facebook price target raised to $450 from $415 at Wells Fargo
07/27/21 Citi
Snap price target raised to $67 from $42 at Citi
07/23/21 Jefferies
Snap price target raised to $90 from $81 at Jefferies
07/23/21 Cowen
Snap price target raised to $96 from $90 at Cowen
TWTR Twitter
$70.74 /

+0.8 (+1.14%)

08:04 Today Wells Fargo
Facebook price target raised to $450 from $415 at Wells Fargo
07/23/21 Jefferies
Twitter price target raised to $80 from $70 at Jefferies
07/23/21 Truist
Twitter price target raised to $80 from $70 at Truist
07/23/21 Oppenheimer
Twitter price target raised to $85 from $70 at Oppenheimer
PINS Pinterest
$74.08 /

-2.66 (-3.47%)

SNAP Snap
$75.90 /

-0.35 (-0.46%)

TWTR Twitter
$70.74 /

+0.8 (+1.14%)

PINS Pinterest
$74.08 /

-2.66 (-3.47%)

SNAP Snap
$75.90 /

-0.35 (-0.46%)

TWTR Twitter
$70.74 /

+0.8 (+1.14%)

PINS Pinterest
$74.08 /

-2.66 (-3.47%)

SNAP Snap
$75.90 /

-0.35 (-0.46%)

TWTR Twitter
$70.74 /

+0.8 (+1.14%)

PINS Pinterest
$74.08 /

-2.66 (-3.47%)

SNAP Snap
$75.90 /

-0.35 (-0.46%)

TWTR Twitter
$70.74 /

+0.8 (+1.14%)

Options
Barrick Gold call volume above normal and directionally bullish » 10:45
07/29/21
07/29
10:45
07/29/21
10:45
GOLD

Barrick Gold

$21.87 /

+0.515 (+2.41%)

Bullish option flow…

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GOLD Barrick Gold
$21.87 /

+0.515 (+2.41%)

GOLD Barrick Gold
$21.87 /

+0.515 (+2.41%)

07/16/21 National Bank
Barrick Gold price target lowered to C$38 from C$39 at National Bank
05/20/21 National Bank
Barrick Gold price target raised to C$39 from C$36 at National Bank
04/27/21 JPMorgan
Barrick Gold price target lowered to $25 from $30 at JPMorgan
02/10/21 JPMorgan
Barrick Gold initiated with a Neutral at JPMorgan
GOLD Barrick Gold
$21.87 /

+0.515 (+2.41%)

GOLD Barrick Gold
$21.87 /

+0.515 (+2.41%)

GOLD Barrick Gold
$21.87 /

+0.515 (+2.41%)

Downgrade
Real Matters downgraded to Sector Perform from Outperform at National Bank » 10:42
07/29/21
07/29
10:42
07/29/21
10:42
RLLMF

Real Matters

$10.60 /

-1.4234 (-11.84%)

National Bank analyst…

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RLLMF Real Matters
$10.60 /

-1.4234 (-11.84%)

08:56 Today TD Securities
Real Matters downgraded to Hold from Buy at TD Securities
04/29/21 Scotiabank
Real Matters price target lowered to C$22 from C$24 at Scotiabank
04/29/21 TD Securities
Real Matters price target lowered to C$22 from C$30 at TD Securities
04/29/21 BMO Capital
Real Matters downgraded to Market Perform from Outperform at BMO Capital
Syndicate
Nuvalent indicated to open at $22, IPO priced at $17 » 10:42
07/29/21
07/29
10:42
07/29/21
10:42
NUVL

Nuvalent

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+

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  • 29
    Jul
Syndicate
Rallybio indicated to open at $15, IPO priced at $13  10:40
07/29/21
07/29
10:40
07/29/21
10:40
RLYB

Rallybio

/

+

 
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  • 29
    Jul
Recommendations
Atreca selloff after preliminary ATRC-101 data appears overdone, says Stifel » 10:39
07/29/21
07/29
10:39
07/29/21
10:39
BCEL

Atreca

$5.33 /

-2.88 (-35.08%)

After Atreca reported…

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BCEL Atreca
$5.33 /

-2.88 (-35.08%)

BCEL Atreca
$5.33 /

-2.88 (-35.08%)

06/03/21 Baird
Atreca tarnsferred with Outperform at Baird
02/08/21 Jefferies
Atreca initiated with a Buy at Jefferies
08/12/20 Stifel
Volatility in Atreca shares creates 'interesting' opportunity, says Stifel
BCEL Atreca
$5.33 /

-2.88 (-35.08%)

BCEL Atreca
$5.33 /

-2.88 (-35.08%)

Initiation
Melrose Industries reinstated with a Buy at Citi » 10:39
07/29/21
07/29
10:39
07/29/21
10:39
MLSPF

Melrose Industries

$2.22 /

+0.0178 (+0.81%)

Citi analyst Edward…

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MLSPF Melrose Industries
$2.22 /

+0.0178 (+0.81%)

06/24/21 UBS
Melrose Industries price target lowered to 185 GBp from 202 GBp at UBS
06/23/21 JPMorgan
Melrose Industries price target raised to 235 GBp from 230 GBp at JPMorgan
05/21/21 JPMorgan
Melrose Industries price target raised to 230 GBp from 215 GBp at JPMorgan
05/21/21 Stifel
Melrose Industries upgraded to Buy from Hold at Stifel
Hot Stocks
Spirit Airlines in 'active' talks to increase flying in NYC, Newark  10:36
07/29/21
07/29
10:36
07/29/21
10:36
SAVE

Spirit Airlines

$28.38 /

-0.135 (-0.47%)

 
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SAVE Spirit Airlines
$28.38 /

-0.135 (-0.47%)

SAVE Spirit Airlines
$28.38 /

-0.135 (-0.47%)

06/15/21
Fly Intel: Top five analyst upgrades
06/15/21 Citi
Spirit Airlines upgraded to Buy from Neutral at Citi
06/09/21 MKM Partners
MKM sees 'a lot to like' in Spirit Airlines' valuation
06/09/21 MKM Partners
Spirit Airlines initiated with a Buy at MKM Partners
SAVE Spirit Airlines
$28.38 /

-0.135 (-0.47%)

SAVE Spirit Airlines
$28.38 /

-0.135 (-0.47%)

SAVE Spirit Airlines
$28.38 /

-0.135 (-0.47%)

SAVE Spirit Airlines
$28.38 /

-0.135 (-0.47%)

Hot Stocks
PG&E says SEC probe into fire disclosures ended with no action » 10:33
07/29/21
07/29
10:33
07/29/21
10:33
PCG

PG&E

$9.18 /

+0.03 (+0.33%)

On March 20, 2019,…

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PCG PG&E
$9.18 /

+0.03 (+0.33%)

PCG PG&E
$9.18 /

+0.03 (+0.33%)

05/25/21 Barclays
PG&E price target lowered to $14 from $15 at Barclays
05/14/21 Mizuho
PG&E price target raised to $16 from $15 at Mizuho
05/03/21 Wells Fargo
PG&E upgraded to Overweight from Equal Weight at Wells Fargo
03/04/21
Fly Intel: Top five analyst upgrades
PCG PG&E
$9.18 /

+0.03 (+0.33%)

PCG PG&E
$9.18 /

+0.03 (+0.33%)

PCG PG&E
$9.18 /

+0.03 (+0.33%)

Hot Stocks
Spirit Airlines sees reaching 2019 unit cost level in mid-2022  10:33
07/29/21
07/29
10:33
07/29/21
10:33
SAVE

Spirit Airlines

$28.37 /

-0.145 (-0.51%)

 
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SAVE Spirit Airlines
$28.37 /

-0.145 (-0.51%)

SAVE Spirit Airlines
$28.37 /

-0.145 (-0.51%)

06/15/21
Fly Intel: Top five analyst upgrades
06/15/21 Citi
Spirit Airlines upgraded to Buy from Neutral at Citi
06/09/21 MKM Partners
MKM sees 'a lot to like' in Spirit Airlines' valuation
06/09/21 MKM Partners
Spirit Airlines initiated with a Buy at MKM Partners
SAVE Spirit Airlines
$28.37 /

-0.145 (-0.51%)

SAVE Spirit Airlines
$28.37 /

-0.145 (-0.51%)

SAVE Spirit Airlines
$28.37 /

-0.145 (-0.51%)

SAVE Spirit Airlines
$28.37 /

-0.145 (-0.51%)

General news
Week of 7/23 EIA natural gas report 36bcf  10:31
07/29/21
07/29
10:31
07/29/21
10:31
$ECON

Economic Data

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$ECON Economic Data
/

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General news
EIA natural gas storage change for week ending July 23 » 10:30
07/29/21
07/29
10:30
07/29/21
10:30
USO

United States Oil Fund

$50.17 /

+0.46 (+0.93%)

Gas inventories were…

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USO United States Oil Fund
$50.17 /

+0.46 (+0.93%)

USO United States Oil Fund
$50.17 /

+0.46 (+0.93%)

Syndicate
Riskified indicated to open at $26, IPO priced at $21  10:29
07/29/21
07/29
10:29
07/29/21
10:29
RSKD

Riskified

$0.00 /

+ (+0.00%)

 
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  • 29
    Jul
Syndicate
Traeger indicated to open at $21, IPO priced at $18  10:29
07/29/21
07/29
10:29
07/29/21
10:29
COOK

Traeger

$0.00 /

+ (+0.00%)

 
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  • 29
    Jul
Recommendations
Workhorse Group price target lowered to $8.50 from $13.00 at Cowen » 10:26
07/29/21
07/29
10:26
07/29/21
10:26
WKHS

Workhorse Group

$11.65 /

+0.36 (+3.19%)

Cowen analyst Jeffrey…

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WKHS Workhorse Group
$11.65 /

+0.36 (+3.19%)

WKHS Workhorse Group
$11.65 /

+0.36 (+3.19%)

06/08/21 Colliers
California HVIP vouchers 'an important development' for EV stocks, says Colliers
06/04/21
Fly Intel: Top five analyst downgrades
06/04/21 Cowen
Workhorse Group downgraded to Market Perform from Outperform at Cowen
05/11/21 B. Riley
B. Riley cuts Workhorse target but says earnings selloff overblown
WKHS Workhorse Group
$11.65 /

+0.36 (+3.19%)

WKHS Workhorse Group
$11.65 /

+0.36 (+3.19%)

WKHS Workhorse Group
$11.65 /

+0.36 (+3.19%)

WKHS Workhorse Group
$11.65 /

+0.36 (+3.19%)

Options
SoFi Technologies call volume above normal and directionally bullish » 10:25
07/29/21
07/29
10:25
07/29/21
10:25
SOFI

SoFi Technologies

$15.80 /

+0.435 (+2.83%)

Bullish option flow…

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SOFI SoFi Technologies
$15.80 /

+0.435 (+2.83%)

SOFI SoFi Technologies
$15.80 /

+0.435 (+2.83%)

06/28/21 Rosenblatt
SoFi Technologies lock-up brings buying opportunity, says Rosenblatt
06/15/21 Rosenblatt
SoFi Technologies initiated with a Buy at Rosenblatt
06/02/21
Fly Intel: Top five analyst initiations
06/01/21 Oppenheimer
SoFi Technologies initiated with an Outperform at Oppenheimer
SOFI SoFi Technologies
$15.80 /

+0.435 (+2.83%)

SOFI SoFi Technologies
$15.80 /

+0.435 (+2.83%)

Hot Stocks
GH Research PLC trading resumes  10:23
07/29/21
07/29
10:23
07/29/21
10:23
GHRS

GH Research

$16.50 /

-0.01 (-0.06%)

 
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GHRS GH Research
$16.50 /

-0.01 (-0.06%)

GHRS GH Research
$16.50 /

-0.01 (-0.06%)

07/20/21
Fly Intel: Top five analyst initiations
07/20/21 Cowen
GH Research initiated with an Outperform at Cowen
07/20/21 Canaccord
GH Research initiated with a Buy at Canaccord
07/20/21 Stifel
GH Research initiated with a Buy at Stifel
  • 25
    Jun
GHRS GH Research
$16.50 /

-0.01 (-0.06%)

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