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DRNA

Dicerna

$31.78 /

+1.39 (+4.57%)

, LLY

Eli Lilly

$200.95 /

+1.8 (+0.90%)

07:40
05/27/21
05/27
07:40
05/27/21
07:40

Dicerna announces FDA acceptance of Lilly's IND application for LY3819469

Dicerna Pharmaceuticals (DRNA) announced the U.S. Food and Drug Administration acceptance of the Investigational New Drug application filed by Eli Lilly (LLY)and Company for LY3819469, the second clinical-stage candidate to emerge from Dicerna's collaboration with Lilly. The IND milestone triggers a $10M payment to Dicerna and enables Lilly to initiate a Phase 1 clinical trial of LY3819469, an investigational GalXC RNAi candidate targeting the LPA gene as a potential treatment of cardiometabolic diseases."This milestone marks the second IND generated through our productive collaboration with Lilly," said Bob D. Brown, Ph.D., Chief Scientific Officer and Executive Vice President of R&D at Dicerna. "In addition to the two candidates now at clinical stage, there are so far, nine discovery research programs connected to this alliance, emphasizing Dicerna's and Lilly's shared commitment to bringing forward new RNAi-based therapies to treat a broad range of diseases." The IND filing for LY3819469 is the second development milestone achieved under a 2018 global licensing and research collaboration between Dicerna and Lilly focused on the discovery, development and commercialization of potential new therapies for cardiometabolic and neurodegenerative diseases and pain. This investigational cardiometabolic therapy and future therapies to emerge from the two companies' collaboration leverage Dicerna's proprietary GalXC RNAi technology platform. Under the agreement, Dicerna is eligible to receive up to $350M in development and commercialization milestones for each GalXC hepatocyte target and $355 million for each non-hepatocyte target, as well as tiered royalties ranging from the mid-single-digits to low double-digits on potential product sales.

DRNA

Dicerna

$31.78 /

+1.39 (+4.57%)

LLY

Eli Lilly

$200.95 /

+1.8 (+0.90%)

  • 27

    May

  • 03

    Jun

DRNA Dicerna
$31.78 /

+1.39 (+4.57%)

04/19/21 Truist
Dicerna price target raised to $45 from $35 at Truist
04/16/21
Fly Intel: Top five analyst initiations
04/16/21 Goldman Sachs
Dicerna initiated with a Buy at Goldman Sachs
03/18/21
Dicerna to hold a webinar on DCR-AUD disorder
LLY Eli Lilly
$200.95 /

+1.8 (+0.90%)

05/24/21 H.C. Wainwright
Aurinia reported positive data as competitors 'stumble,' says H.C. Wainwright
04/28/21 Mizuho
Eli Lilly price target lowered to $216 from $228 at Mizuho
04/28/21 Barclays
Eli Lilly price target lowered to $227 from $232 at Barclays
04/12/21 Benchmark
Benchmark sees full FDA approval of Regeneron's REGEN-COV coming

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Initiation
KVH Industries initiated with a Buy at Needham » 07:21
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KVH Industries

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Downgrade
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Raven

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$57.61 /

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Lithia Motors

$321.82 /

+7.96 (+2.54%)

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Earnings
Topps sees 2021 revenue $740M-$760M » 07:15
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MUDS

Mudrick Capital Acquisition Corporation II

$11.40 /

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Topps

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MUDS Mudrick Capital Acquisition Corporation II
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MUDS Mudrick Capital Acquisition Corporation II
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Earnings
Topps reports Q1 revenue $166.6M vs. $107.28M last year » 07:14
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Mudrick Capital Acquisition Corporation II

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Hot Stocks
SPAC Thimble Point Acquisition in combination to create Pear Therapeutics » 07:13
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$9.73 /

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Verisk Analytics launches refinery intelligence tool » 07:12
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Verisk Analytics

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Initiation
TSMC initiated with a Buy at Argus » 07:11
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TSM

TSMC

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Argus analyst Jim…

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Syndicate
GameStop completes at-the-market equity offering program » 07:09
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GME

GameStop

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-13.82 (-6.46%)

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Hot Stocks
Quanergy to become public through CITIC Capital Acquisition business combination » 07:09
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QNGY

Quanergy

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, CCAC

CITIC Capital Acquisition

$9.95 /

+ (+0.00%)

Quanergy Systems (QNGY)…

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Hot Stocks
Points International partners with Bilt Rewards for loyalty program for renters » 07:08
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PCOM

Points International

$17.01 /

+0.18 (+1.07%)

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$17.01 /

+0.18 (+1.07%)

PCOM Points International
$17.01 /

+0.18 (+1.07%)

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Hot Stocks
Plug Power aims to achieve 2022 gross billings $750M » 07:07
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Plug Power

$29.87 /

+0.64 (+2.19%)

Reaffirms recently raised…

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$29.87 /

+0.64 (+2.19%)

PLUG Plug Power
$29.87 /

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PLUG Plug Power
$29.87 /

+0.64 (+2.19%)

  • 27
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PLUG Plug Power
$29.87 /

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PLUG Plug Power
$29.87 /

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Hot Stocks
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AvalonBay

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+6.05 (+2.94%)

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$212.08 /

+6.05 (+2.94%)

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Initiation
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07:05
SAR

Saratoga Investment

$26.07 /

+0.31 (+1.20%)

Raymond James analyst…

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SAR Saratoga Investment
$26.07 /

+0.31 (+1.20%)

SAR Saratoga Investment
$26.07 /

+0.31 (+1.20%)

06/15/21 Oppenheimer
Saratoga Investment initiated with an Outperform at Oppenheimer
06/15/21 Oppenheimer
Saratoga Investment initiated with an Outperform at Oppenheimer
05/07/21 B. Riley
Saratoga Investment price target raised to $29 from $26 at B. Riley
03/05/21 Hovde Group
Saratoga Investment initiated with an Outperform at Hovde Group
SAR Saratoga Investment
$26.07 /

+0.31 (+1.20%)

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