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2022-03-31 12:58:48 ORTX Orchard Therapeutics / + 12:58 03/31/22 03/31 12:58 03/31/22 12:58	Orchard Therapeutics price target lowered to $5 from $12 at Stifel Stifel analyst Dae Gon Ha lowered the firm's price target on Orchard Therapeutics to $5 from $12 and keeps a Buy rating on the shares. Strategic reorganization extends cash runway into 2024, and importantly focuses on lessons from Libmeldy, the analyst notes. Investor sentiment remains cautious on lentivirus gene therapy, and he agrees that prudence on strategic alignment behind de-risked program/mechanism and cash expense is worthwhile. To that end, the analyst continues to view Libmeldy BLA submission as an important catalyst - potentially an inflection point - that may help recalibrate investor sentiment on LV. Whereas reorganization renders primary immunodeficiency programs as potential sources of partnerships and non-dilutive financing, he is removing the programs from his model - OTL-103 and OTL-102.

2022-03-31 12:58:48

ORTX

Orchard Therapeutics

/ +

12:58

03/31/22

03/31

12:58

03/31/22

12:58

Orchard Therapeutics price target lowered to $5 from $12 at Stifel

Stifel analyst Dae Gon Ha lowered the firm's price target on Orchard Therapeutics to $5 from $12 and keeps a Buy rating on the shares. Strategic reorganization extends cash runway into 2024, and importantly focuses on lessons from Libmeldy, the analyst notes. Investor sentiment remains cautious on lentivirus gene therapy, and he agrees that prudence on strategic alignment behind de-risked program/mechanism and cash expense is worthwhile. To that end, the analyst continues to view Libmeldy BLA submission as an important catalyst - potentially an inflection point - that may help recalibrate investor sentiment on LV. Whereas reorganization renders primary immunodeficiency programs as potential sources of partnerships and non-dilutive financing, he is removing the programs from his model - OTL-103 and OTL-102.

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DELL NTAP AAPL DELL Dell Technologies $40.61 / -1.625 (-3.85%) 11/21/22 Dell Technologies options imply 6.3% move in share price post-earnings 11/07/22 Dell Technologies call volume above normal and directionally bullish 10/10/22 Dell Technologies put volume heavy and directionally bearish 09/14/22 Dell Technologies call volume above normal and directionally bullish NTAP NetApp $66.56 / -1.1 (-1.63%) 12/01/22 Largest borrow rate increases among liquid names 11/29/22 NetApp options imply 5.7% move in share price post-earnings 08/25/22 Early notable gainers among liquid option names on August 25th 08/24/22 NetApp options imply 5.7% move in share price post-earnings AAPL Apple $152.25 / -2.245 (-1.45%) 08:55 Today Notable open interest changes for February 6th 07:35 Today Unusual call flow in option market yesterday 02/03/23 Apple option volume tops 3M contracts following earnings, 3x normal 02/03/23 Notable open interest changes for February 3rd
Hot Stocks	Mountain Crest Acquisition Corp. Iii trading resumes 11:07 02/06/23 02/06 11:07 02/06/23 11:07
Options	Barrick Gold call volume above normal and directionally bullish » 11:05 02/06/23 02/06 11:05 02/06/23 11:05 GOLD Barrick Gold $18.25 / -0.06 (-0.33%) Bullish option flow… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings Periodicals Events Options GOLD Barrick Gold $18.25 / -0.06 (-0.33%) 02/01/23 Barrick Gold hosts North Mara site visit for human rights NGO 01/31/23 Barrick Gold makes initial $3M payment to Balochistan government for Reko Diq 01/25/23 Barrick Gold says Tanzania gold mines produce 547,000 ounces in 2022 01/17/23 Barrick Gold reports preliminary Q4 gold production 1% lower than 4.2M ozs GOLD Barrick Gold $18.25 / -0.06 (-0.33%) 01/30/23 Barclays Barrick Gold price target raised to $26 from $23 at Barclays 01/13/23 National Bank Barrick Gold price target raised to C$30 from C$25 at National Bank 11/29/22 National Bank Barrick Gold price target raised to C$25 from C$24 at National Bank 11/21/22 RBC Capital Barrick Gold price target lowered to $20 from $27 at RBC Capital GOLD Barrick Gold $18.25 / -0.06 (-0.33%) 11/03/22 Barrick Gold reports Q3 adjusted EPS 13c, consensus 31c 08/08/22 Barrick Gold reports Q2 adjusted EPS 24c, consensus 31c GOLD Barrick Gold $18.25 / -0.06 (-0.33%) 10/15/22 BHP among mining stocks with bright long-term outlook, Barron's says 02/15/23 Barrick Gold - GOLD GOLD Barrick Gold $18.25 / -0.06 (-0.33%) 02/03/23 Barrick Gold call volume above normal and directionally bullish 02/03/23 Unusually active option classes on open February 3rd 01/19/23 Barrick Gold call volume above normal and directionally bullish 12/27/22 Barrick Gold call volume above normal and directionally bullish
Hot Stocks	Mountain Crest Acquisition Corp. Iii trading halted, volatility trading pause 11:02 02/06/23 02/06 11:02 02/06/23 11:02

Events

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Match Group - MTCH Conference Calls
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Chegg - CHGG Conference Calls
TTWO
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Syndicate

This week’s upcoming IPOs and secondary offerings

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Mon	No deals
Tues	No deals
Wed	NXT X NXT Nextracker IPO Managers: JPMorgan, BofA, Citi & Barclays, Truist, HSBC, BNP Paribas, Mizuho, Scotiabank, KeyBanc $20.00-23.00 23.26M Shares Special Comments Ratings Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial
Thurs	ENLT X ENLT Enlight Renewable Energy IPO Managers: JPMorgan, BofA & Barclays, Credit Suisse, Wolfe Research, Nomura, HSBC, Roth MKM $20.57 14M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial LEWY X LEWY LeeWay Services IPO Managers: ThinkEquity $5.00 1M Shares MLYS X MLYS Mineralys Therapeutics IPO Managers: BofA, Ever Bank, Stifel, Credit Suisse, Guggenheim & Wells Fargo $14.00-16.00 10M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial
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Orchard Therapeutics price target lowered to $5 from $12 at Stifel

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