2022-05-18 08:20:51 PPBT Purple Biotech
Bristol-Myers
05/18/22 05/1808:20 05/18/2208:20 | Purple Biotech announces initiation of Phase 2 study for CM24Purple Biotech (PPBT) announced the initiation of the Phase 2 portion of its ongoing study of CM24, a first-in-class monoclonal antibody with the potential to treat multiple cancers. The Phase 2 is an open-label, multicenter study in subjects with metastatic pancreatic cancer, PDAC, to evaluate the safety and tolerability of CM24 in combination with the PD-1 inhibitor Opdivo and chemotherapy. The primary study endpoint is to evaluate preliminary efficacy in 2nd line PDAC. The phase 2 portion of the study is being conducted as part of Purple Biotech's clinical collaboration with Bristol Myers Squibb (BMY). The companies together made the determination to prioritize PDAC over non-small cell lung cancer based on the positive interim data. Accordingly, this decision will allow an increase in the number of subjects that will be participating, and will accelerate this part of the study, and the updated timeline to complete this trial is within 2023. "We are thrilled at the progress being made to help move this treatment forward in the clinical trial process for the potential benefit of patients with pancreatic cancer," said Gil Efron, President and CFO of Purple Biotech. "We are thankful for our partners at BMS for collaborating with us on this study and their support. Importantly, the decision to prioritize the PDAC study will extend the cash runway of Purple Biotech through the end of 2024," added Efron. Purple Biotech
Bristol-Myers
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