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2022-06-16 08:39:54 MBRX Moleculin Biotech $1.40 / +0.015 (+1.08%) 08:39 06/16/22 06/16 08:39 06/16/22 08:39	Moleculin Biotech completes first cohort in Phase 1a trial of COVID-19 candidate Moleculin Biotech reported preliminary results from the first cohort of the xompany's first-in-human Phase 1a study of WP1122. This cohort consisted of 9 subjects dosed with 8 mg/kg or placebo in the dose escalation trial evaluating the safety and pharmacokinetics of WP1122 in healthy volunteers in the UK. Based on the overall results in Cohort 1, the company deemed the first cohort dose safe and well-tolerated and will open SAD Cohort 2 with a dose escalation to 16 mg/kg. The Phase 1a, first-in-human, randomized, double-blind, placebo-controlled, overlapping SAD and MAD is investigating the effects of WP1122 administered as an oral solution in healthy human volunteers. It is the first step in a planned investigation of WP1122 for the treatment of COVID-19. The company expects to enroll approximately 80 subjects in this trial. Moleculin is also in the process of identifying additional countries where potential future Phase 2 COVID-19 clinical studies could occur.

2022-06-16 08:39:54

MBRX

Moleculin Biotech

$1.40 / +0.015 (+1.08%)

08:39

06/16/22

06/16

08:39

06/16/22

08:39

Moleculin Biotech completes first cohort in Phase 1a trial of COVID-19 candidate

Moleculin Biotech reported preliminary results from the first cohort of the xompany's first-in-human Phase 1a study of WP1122. This cohort consisted of 9 subjects dosed with 8 mg/kg or placebo in the dose escalation trial evaluating the safety and pharmacokinetics of WP1122 in healthy volunteers in the UK. Based on the overall results in Cohort 1, the company deemed the first cohort dose safe and well-tolerated and will open SAD Cohort 2 with a dose escalation to 16 mg/kg. The Phase 1a, first-in-human, randomized, double-blind, placebo-controlled, overlapping SAD and MAD is investigating the effects of WP1122 administered as an oral solution in healthy human volunteers. It is the first step in a planned investigation of WP1122 for the treatment of COVID-19. The company expects to enroll approximately 80 subjects in this trial. Moleculin is also in the process of identifying additional countries where potential future Phase 2 COVID-19 clinical studies could occur.

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Recommendations	Exchange Income price target raised to C$60 from C$56 at Scotiabank » 11:01 08/15/22 08/15 11:01 08/15/22 11:01 EIFZF Exchange Income $38.22 / +0.88 (+2.36%) Scotiabank analyst Konark… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Street Research EIFZF Exchange Income $38.22 / +0.88 (+2.36%) 10:52 Today TD Securities Exchange Income price target raised to C$67 from C$59 at TD Securities 05/17/22 RBC Capital Exchange Income price target raised to C$62 from C$52 at RBC Capital 05/13/22 Raymond James Exchange Income price target raised to C$62 from C$55 at Raymond James 05/12/22 Canaccord Exchange Income price target raised to C$58 from C$52 at Canaccord
Hot Stocks	Keysight Technologies extends collaboration with Synopsys » 11:01 08/15/22 08/15 11:01 08/15/22 11:01 KEYS Keysight Technologies $169.67 / +0.1 (+0.06%) , SNPS Synopsys $387.37 / +2.04 (+0.53%) Keysight Technologies… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in 9 minutes Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings Periodicals On The Fly Events Options KEYS SNPS KEYS Keysight Technologies $169.67 / +0.1 (+0.06%) 08/03/22 Keysight, Nokia collaborate on public 800GE test 07/29/22 The Digital IF Interoperability Consortium announces seven new members 07/13/22 AI-LINK selects Keysight's 5G test tools for performance validation 06/22/22 Keysight selected by Azcom for verifying O-RAN equipment SNPS Synopsys $387.37 / +2.04 (+0.53%) 06/22/22 Synopsys sees WhiteHat Security acquisition neutral to FY22 adjusted EPS 05/27/22 Synopsys initiates $200M ASR with Wells Fargo 05/24/22 Synopsys enters distribution agreement with Arrow Electronics 05/23/22 Synopsys, Analog Devices announce collaboration KEYS SNPS KEYS Keysight Technologies $169.67 / +0.1 (+0.06%) 08/09/22 Deutsche Bank Keysight Technologies price target raised to $190 from $176 at Deutsche Bank 07/14/22 JPMorgan Keysight Technologies price target lowered to $176 from $200 at JPMorgan 06/17/22 UBS Keysight Technologies price target lowered to $177 from $220 at UBS 06/01/22 Goldman Sachs Keysight Technologies price target lowered to $165 from $185 at Goldman Sachs SNPS Synopsys $387.37 / +2.04 (+0.53%) 08/11/22 Wells Fargo Synopsys price target raised to $425 from $375 at Wells Fargo 06/29/22 BofA Synopsys upgraded to Neutral from Underperform at BofA 05/19/22 Needham Synopsys price target raised to $380 from $370 at Needham 05/19/22 Wells Fargo Synopsys price target lowered to $375 from $415 at Wells Fargo KEYS SNPS KEYS Keysight Technologies $169.67 / +0.1 (+0.06%) 05/17/22 Keysight Technologies sees FY22 EPS up 14%-15%, consensus $7.01 05/17/22 Keysight Technologies sees Q3 EPS $1.74-$1.80, consensus $1.75 05/17/22 Keysight Technologies reports Q2 EPS $1.83, consensus $1.67 02/17/22 Keysight Technologies sees Q2 adjusted EPS $1.63-$1.69, consensus $1.64 SNPS Synopsys $387.37 / +2.04 (+0.53%) 05/18/22 Synopsys sees FY22 non-GAAP EPS $8.63-$8.70, consensus $7.90 05/18/22 Synopsys sees Q2 non-GAAP EPS $2.01-$2.06, consensus $1.61 05/18/22 Synopsys reports Q2 non-GAAP EPS $2.50, consensus $2.37 05/18/22 Notable companies reporting after market close SNPS SNPS Synopsys $387.37 / +2.04 (+0.53%) 04/13/22 Synopsys probed by Commerce Department over China, Bloomberg reports 04/13/22 Synopsys sent subpoena from Commerce Department on China, Blomberg says KEYS SNPS KEYS Keysight Technologies $169.67 / +0.1 (+0.06%) 03/11/22 Street Wrap: Today's Top 15 Upgrades, Downgrades, Initiations SNPS Synopsys $387.37 / +2.04 (+0.53%) 05/19/22 Fly Intel: Pre-market Movers 05/18/22 Fly Intel: After-Hours Movers 04/13/22 What You Missed On Wall Street On Wednesday 08/17/22 Keysight Technologies - KEYS 08/17/22 Synopsys - SNPS SNPS SNPS Synopsys $387.37 / +2.04 (+0.53%) 05/19/22 Early notable gainers among liquid option names on May 19th
Recommendations	CES Energy Solutions price target raised to C$3.90 from C$3.60 at Scotiabank » 10:58 08/15/22 08/15 10:58 08/15/22 10:58 CESDF CES Energy Solutions $2.24 / +0.0438 (+2.00%) Scotiabank analyst… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Street Research CESDF CES Energy Solutions $2.24 / +0.0438 (+2.00%) 08/12/22 BMO Capital CES Energy Solutions price target raised to C$4 from C$3.50 at BMO Capital 08/12/22 Stifel CES Energy Solutions price target raised to C$4.50 from C$3.75 at Stifel 08/12/22 RBC Capital CES Energy Solutions price target raised to C$4 from C$3.50 at RBC Capital 08/12/22 TD Securities CES Energy Solutions price target raised to C$5.50 from C$5 at TD Securities
Recommendations	Canadian Apartment Properties price target lowered to C$59.25 at Scotiabank » 10:57 08/15/22 08/15 10:57 08/15/22 10:57 CDPYF Canadian Apartment Properties $37.32 / +0.09 (+0.24%) Scotiabank analyst Mario… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in 9 minutes Get Free Trial ShowHide Related Items >><< Company News Street Research CDPYF Canadian Apartment Properties $37.32 / +0.09 (+0.24%) 06/30/22 Canadian Apartment Properties appoints Julian Schonfeldt as CIO 05/02/22 Canadian Apartment Properties purchases 172-site MHC in Alberta CDPYF Canadian Apartment Properties $37.32 / +0.09 (+0.24%) 08/12/22 RBC Capital Canadian Apartment Properties price target raised to C$62 at RBC Capital 08/12/22 National Bank Canadian Apartment Properties price target raised to C$52 at National Bank 08/12/22 TD Securities Canadian Apartment Properties price target raised to C$60 at TD Securities 07/20/22 National Bank CAP REIT price target lowered to C$50 from C$62.25 at National Bank
Recommendations	Shawcor price target raised to C$10 from C$7.50 at TD Securities » 10:55 08/15/22 08/15 10:55 08/15/22 10:55 SAWLF Shawcor $4.77 / +0.03 (+0.63%) TD Securities analyst… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Company News Street Research SAWLF Shawcor $4.77 / +0.03 (+0.63%) 05/02/22 CloudMD appoints Tano to board of directors 02/18/22 Shawcor receives contract for application of LotusFlo technology SAWLF Shawcor $4.77 / +0.03 (+0.63%) 07:22 Today Industrial Alliance Shawcor upgraded to Buy from Speculative Buy at Industrial Alliance 08/12/22 BMO Capital Shawcor price target raised to C$8 from C$7 at BMO Capital 05/16/22 RBC Capital Shawcor price target raised to C$8 from C$7 at RBC Capital 05/16/22 TD Securities Shawcor upgraded to Buy from Hold at TD Securities

Recommendations	Aimia price target lowered to C$7 from C$7.50 at TD Securities » 10:55 08/15/22 08/15 10:55 08/15/22 10:55 AIMFF Aimia $3.53 / -0.08 (-2.22%) TD Securities analyst… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in 9 minutes Get Free Trial ShowHide Related Items >><< Street Research AIMFF Aimia $3.53 / -0.08 (-2.22%) 03/31/22 TD Securities Aimia price target raised to C$7.50 from C$7 at TD Securities 02/09/22 RBC Capital Aimia downgraded to Sector Perform from Outperform at RBC Capital
Options	DocuSign put volume heavy and directionally bearish » 10:55 08/15/22 08/15 10:55 08/15/22 10:55 DOCU DocuSign $75.24 / +0.91 (+1.22%) Bearish flow noted in… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings Periodicals On The Fly Options DOCU DocuSign $75.24 / +0.91 (+1.22%) 06/21/22 DocuSign CEO Dan Springer to step down, Mary Agnes Wilderotter named interim CEO 06/09/22 DocuSign reports Q1 subscription revenue $569.3M, up 26% y/y 06/09/22 DocuSign drops 12% to $76.88 after Q1 profit misses estimates 06/07/22 DocuSign jumps 4% to $91.27 after announcing expanded partnership with Microsoft DOCU DocuSign $75.24 / +0.91 (+1.22%) 07/21/22 Piper Sandler DocuSign downgraded to Underweight on elevated risks at Piper Sandler 07/20/22 Piper Sandler DocuSign downgraded to Underweight from Neutral at Piper Sandler 07/13/22 Piper Sandler DocuSign price target lowered to $65 from $75 at Piper Sandler 06/22/22 JMP Securities JMP Securities maintains Outperform on DocuSign amid CEO departure DOCU DocuSign $75.24 / +0.91 (+1.22%) 06/09/22 DocuSign sees FY23 revenue $2.47B-$2.482B, consensus $2.48B 06/09/22 DocuSign sees Q2 revenue $600M-$604M, consensus $601.71M 06/09/22 DocuSign reports Q1 adjusted EPS 38c, consensus 46c 06/09/22 Notable companies reporting after market close DOCU DocuSign $75.24 / +0.91 (+1.22%) 07/01/22 DocuSign challenges could lead to activist or suitor, The Deal says DOCU DocuSign $75.24 / +0.91 (+1.22%) 07/21/22 What You Missed On Wall Street On Thursday 07/21/22 What You Missed On Wall Street This Morning 07/21/22 Street Wrap: Today's Top 15 Upgrades, Downgrades, Initiations 06/21/22 What You Missed On Wall Street This Morning DOCU DocuSign $75.24 / +0.91 (+1.22%) 07/26/22 DocuSign put volume heavy and directionally bearish 06/09/22 DocuSign options imply 12.7% move in share price post-earnings 05/25/22 DocuSign call volume above normal and directionally bullish 04/20/22 DocuSign put volume heavy and directionally bearish
Recommendations	Timbercreek Financial price target raised to C$9 from C$8.50 at TD Securities » 10:54 08/15/22 08/15 10:54 08/15/22 10:54 TBCRF Timbercreek Financial $6.61 / + (+0.00%) TD Securities analyst… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in 9 minutes Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings TBCRF Timbercreek Financial $6.61 / + (+0.00%) 05/24/22 Timbercreek Financial announces normal course issuer bid TBCRF Timbercreek Financial $6.61 / + (+0.00%) 07/27/22 National Bank Timbercreek price target lowered to C$8.75 from C$9.50 at National Bank 05/13/22 TD Securities Timbercreek Financial price target lowered to C$9 from C$9.50 at TD Securities 05/11/22 Canaccord Timbercreek Financial price target lowered to C$9.75 from C$10.25 at Canaccord 04/26/22 National Bank Timbercreek Financial price target lowered to C$9.50 from C$10 at National Bank TBCRF Timbercreek Financial $6.61 / + (+0.00%) 08/11/22 Timbercreek Financial reports Q2 adjusted EPS C$0.18 vs. C$0.17 last year 05/10/22 Timbercreek Financial reports Q1 adjusted EPS C17c vs. C17c last year 02/24/22 Timbercreek Financial reports Q4 adjusted EPS C$0.17 vs. C$0.16 last year
Recommendations	Sienna Senior Living price target raised to C$17 from C$16 at TD Securities » 10:54 08/15/22 08/15 10:54 08/15/22 10:54 LWSCF Sienna Senior Living $11.07 / +0.3449 (+3.22%) TD Securities analyst… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Company News Street Research LWSCF Sienna Senior Living $11.07 / +0.3449 (+3.22%) 04/06/22 Sienna Senior Living CFO Karen Hon to depart, David Hung to succeed LWSCF Sienna Senior Living $11.07 / +0.3449 (+3.22%) 07/20/22 National Bank Sienna Senior Living price target lowered to C$15 from C$17.50 at National Bank 05/19/22 RBC Capital Sienna Senior Living price target lowered to C$16 from C$16.50 at RBC Capital 05/16/22 TD Securities Sienna Senior Living price target lowered to C$17.50 from C$18 at TD Securities 03/25/22 Scotiabank Sienna Senior Living price target raised to C$17 from C$16.50 at Scotiabank
Recommendations	Park Lawn price target lowered to C$43 from C$47 at TD Securities » 10:53 08/15/22 08/15 10:53 08/15/22 10:53 PRRWF Park Lawn $23.75 / -0.86 (-3.49%) TD Securities analyst… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in 9 minutes Get Free Trial ShowHide Related Items >><< Street Research PRRWF Park Lawn $23.75 / -0.86 (-3.49%) 08/12/22 RBC Capital Park Lawn price target lowered to C$49 from C$50 at RBC Capital 08/09/22 RBC Capital Park Lawn price target lowered to C$50 from C$54 at RBC Capital 06/27/22 Scotiabank Park Lawn price target lowered to C$42 from C$43 at Scotiabank 05/16/22 Scotiabank Park Lawn price target lowered to C$43 from C$44 at Scotiabank

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