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2022-12-06 05:45:53 NTRA Natera $40.40 / -1.45 (-3.46%) 05:45 12/06/22 12/06 05:45 12/06/22 05:45	Natera publishes experience study in twin pregnancies in Prenatal Diagnosis Natera announced the publication in Prenatal Diagnosis of a clinical experience study in twin pregnancies featuring its Panorama single nucleotide polymorphism, or SNP-based noninvasive prenatal test, or NIPT. These real-world results are consistent with previously reported performance of NIPT in twins, and reinforce the importance of Panorama's unique ability to determine zygosity and incorporate this information into risk assessments. In this study, from a pool of 18,984 twin pregnancy results over a 27-month period in Natera's laboratory, investigators sought clinical outcomes from all cases reported as high-risk. Outcomes were obtained for 105 high-risk cases, representing 51.2% of the reported high-risk results. Key findings include: across all twins with cytogenetic confirmation, the positive predictive value, or PPV, of screening for trisomy 21 was 88.7%. When cases with findings suggestive of aneuploidy are included, the PPV for trisomy 21 was 90.4%. Dizygotic twin cases confirmed cytogenetically had an estimated PPV of 88.1% for trisomy 21, and 85% for all aneuploidies, the first time NIPT PPVs have been reported specifically for DZ twins. Monozygotic twin cases, both those confirmed cytogenetically and with findings suggestive of aneuploidy, had a PPV of 100% for trisomy 21 and trisomy 18. This study provides additional evidence to earlier findings that aneuploidy rates are higher in DZ than in MZ twin pregnancies.1 In this study, DZ twins had a positive call rate 8-fold higher than MZ twins.	16 Nov

2022-12-06 05:45:53

NTRA

Natera

$40.40 / -1.45 (-3.46%)

05:45

12/06/22

12/06

05:45

12/06/22

05:45

Natera publishes experience study in twin pregnancies in Prenatal Diagnosis

Natera announced the publication in Prenatal Diagnosis of a clinical experience study in twin pregnancies featuring its Panorama single nucleotide polymorphism, or SNP-based noninvasive prenatal test, or NIPT. These real-world results are consistent with previously reported performance of NIPT in twins, and reinforce the importance of Panorama's unique ability to determine zygosity and incorporate this information into risk assessments. In this study, from a pool of 18,984 twin pregnancy results over a 27-month period in Natera's laboratory, investigators sought clinical outcomes from all cases reported as high-risk. Outcomes were obtained for 105 high-risk cases, representing 51.2% of the reported high-risk results. Key findings include: across all twins with cytogenetic confirmation, the positive predictive value, or PPV, of screening for trisomy 21 was 88.7%. When cases with findings suggestive of aneuploidy are included, the PPV for trisomy 21 was 90.4%. Dizygotic twin cases confirmed cytogenetically had an estimated PPV of 88.1% for trisomy 21, and 85% for all aneuploidies, the first time NIPT PPVs have been reported specifically for DZ twins. Monozygotic twin cases, both those confirmed cytogenetically and with findings suggestive of aneuploidy, had a PPV of 100% for trisomy 21 and trisomy 18. This study provides additional evidence to earlier findings that aneuploidy rates are higher in DZ than in MZ twin pregnancies.1 In this study, DZ twins had a positive call rate 8-fold higher than MZ twins.

16
Nov

OTHER BREAKING NEWS FROM THE FLY

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Recommendations	BP price target raised to 1,000 GBp from 700 GBp at Barclays » 15:07 02/08/23 02/08 15:07 02/08/23 15:07 BP BP $38.65 / +0.92 (+2.44%) Barclays analyst Lydia… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings Periodicals On The Fly Options BP BP $38.65 / +0.92 (+2.44%) 02/07/23 BP aims for $51B-$56B group EBITDA in 2023 02/07/23 BP sees FY23 CapEx $16B-$18B 01/17/23 Tritium says BP has placed largest order in company history 01/04/23 BP increases investment in onshore U.S. oil and gas to $2.4B in 2023 BP BP $38.65 / +0.92 (+2.44%) 09:18 Today RBC Capital BP price target raised to 650 GBp from 550 GBp at RBC Capital 06:25 Today Bernstein BP price target raised to $53 from $48 at Bernstein 02/07/23 TD Securities BP upgraded to Buy from Hold at TD Securities 01/23/23 Morgan Stanley BP price target raised to 636 GBp from 603 GBp at Morgan Stanley BP BP $38.65 / +0.92 (+2.44%) 02/07/23 BP reports Q4 EPS $1.59, consensus $1.67 11/01/22 BP reports Q3 EPS $2.59, consensus $1.94 BP BP $38.65 / +0.92 (+2.44%) 01/18/23 U.S. Energy Secretary warns GOP of oil bill risks, Reuters says 01/10/23 ExxonMobil led group develops1.3B barrel off shore Guyana field, AP reports 12/05/22 BP bets big on hydrogen as fuel of the future, Reuters reports 12/04/22 OPEC+ keeps oil curbs despite Russia price cap, WSJ reports BP BP $38.65 / +0.92 (+2.44%) 02/07/23 What You Missed On Wall Street On Tuesday 02/07/23 What You Missed On Wall Street This Morning 12/05/22 What You Missed On Wall Street On Monday 12/05/22 What You Missed On Wall Street This Morning BP BP $38.65 / +0.92 (+2.44%) 01/20/23 Unusually active option classes on open January 20th 01/09/23 $600k upside call Seller in BP 12/16/22 Unusually active option classes on open December 16th 11/28/22 BP put volume heavy and directionally bearish
Recommendations	Aston Martin Lagonda price target raised to 200 GBp from 175 GBp at Barclays » 15:06 02/08/23 02/08 15:06 02/08/23 15:06 ARGGY Aston Martin Lagonda $2.07 / +0.0296 (+1.45%) Barclays raised the… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Street Research ARGGY Aston Martin Lagonda $2.07 / +0.0296 (+1.45%) 01/10/23 Goldman Sachs Aston Martin Lagonda reinstated with a Neutral at Goldman Sachs 11/15/22 Jefferies Aston Martin Lagonda downgraded to Hold from Buy at Jefferies 11/10/22 Barclays Aston Martin Lagonda initiated with an Overweight at Barclays 11/03/22 Deutsche Bank Aston Martin Lagonda price target lowered to 145 GBp at Deutsche Bank
Options	Mattel options imply 6.2% move in share price post-earnings » 15:04 02/08/23 02/08 15:04 02/08/23 15:04 MAT Mattel $20.46 / -0.29 (-1.40%) Pre-earnings options… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings On The Fly Events Options MAT Mattel $20.46 / -0.29 (-1.40%) 01/31/23 Mattel, Minecraft announce partnership 01/09/23 Mattel's Fisher-Price re-announces recall of 4.7M Rock 'n Play Sleepers 10/25/22 Mattel says price increase not producing 'meaningful impact on demand' 10/25/22 Mattel says re-evaluating outlook for FY23, expects top and bottom line growth MAT Mattel $20.46 / -0.29 (-1.40%) 01/31/23 Goldman Sachs Mattel assumed with a Buy at Goldman Sachs 10/26/22 DA Davidson Mattel price target lowered to $31 from $45 at DA Davidson 10/13/22 Jefferies Mattel price target lowered to $22, transferred with a Hold at Jefferies 10/05/22 Stifel Hasbro price target lowered to $84 from $99 at Stifel MAT Mattel $20.46 / -0.29 (-1.40%) 12:48 Today Notable companies reporting after market close 10/25/22 Mattel cuts FY22 EPS view to $1.32-$1.42 from $1.42-$1.48 10/25/22 Mattel reports Q3 EPS 82c, consensus 74c 10/25/22 Notable companies reporting after market close MAT Mattel $20.46 / -0.29 (-1.40%) 02/01/23 Street Wrap: Today's Top 15 Upgrades, Downgrades, Initiations 10/25/22 Fly Intel: After-Hours Movers 08/18/22 Street Wrap: Today's Top 15 Upgrades, Downgrades, Initiations 17:00 Today Mattel - MAT MAT Mattel $20.46 / -0.29 (-1.40%) 01/09/23 Mattel put volume heavy and directionally bearish 10/25/22 Mattel options imply 7.0% move in share price post-earnings 10/19/22 Mattel call volume above normal and directionally bullish 10/04/22 Mattel Inc call volume above normal and directionally bullish

Recommendations	Zur Rose Group price target raised to CHF 60 from CHF 30 at Berenberg » 15:00 02/08/23 02/08 15:00 02/08/23 15:00 ZRSEF Zur Rose Group $27.06 / + (+0.00%) Berenberg analyst Gerhard… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Street Research ZRSEF Zur Rose Group $27.06 / + (+0.00%) 02/07/23 Deutsche Bank Zur Rose Group price target raised to CHF 56 from CHF 22 at Deutsche Bank 02/07/23 UBS Zur Rose Group price target raised to CHF 43 from CHF 23.50 at UBS 02/06/23 Jefferies Zur Rose Group upgraded to Buy from Hold at Jefferies 02/06/23 Deutsche Bank Zur Rose Group upgraded to Hold from Sell at Deutsche Bank
Recommendations	Ubisoft price target lowered to EUR 23 from EUR 42 at Berenberg » 15:00 02/08/23 02/08 15:00 02/08/23 15:00 UBSFY Ubisoft $4.46 / +0.06 (+1.36%) Berenberg analyst Jamie… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings Periodicals On The Fly UBSFY Ubisoft $4.46 / +0.06 (+1.36%) 01/19/23 Sony announces additional games coming to PlayStation VR2 01/17/23 U.S. video game consumer spending rose 2% y/y in December, says NPD 01/17/23 'Call of Duty: Modern Warfare 2' top game seller in U.S. in December, says NPD 01/11/23 Ubisoft unveils revenue growth measures, cancels three unannounced projects UBSFY Ubisoft $4.46 / +0.06 (+1.36%) 01/31/23 Jefferies Ubisoft assumed with Underperform from Buy at Jefferies 01/19/23 HSBC Ubisoft downgraded to Hold from Buy at HSBC 01/13/23 Barclays Ubisoft price target lowered to EUR 19.50 from EUR 28.50 at Barclays 01/13/23 Deutsche Bank Ubisoft price target lowered to EUR 30 from EUR 40 at Deutsche Bank UBSFY Ubisoft $4.46 / +0.06 (+1.36%) 01/11/23 Ubisoft cuts Q3 net bookings view to EUR725M from EUR830M 01/11/23 Ubisoft cuts FY23 operating income view to (EUR500M) from EUR400M UBSFY Ubisoft $4.46 / +0.06 (+1.36%) 02/06/23 Ubisoft+ on Xbox may be imminent, Windows Central reports 01/18/23 Video game sales fell 13% y/y in Europe in December, GI.biz says 01/18/23 Union calls on Ubisoft workers to strike next week, Kotaku reports 01/11/23 Ubisoft sees FY23 operating income in the red, Bloomberg says UBSFY Ubisoft $4.46 / +0.06 (+1.36%) 02/07/23 What You Missed This Week in Video Games 01/31/23 What You Missed This Week in Video Games 01/24/23 What You Missed This Week in Video Games 01/17/23 What You Missed This Week in Video Games
Recommendations	Stillfront Group price target lowered to SEK 35 from SEK 45 at Berenberg » 14:59 02/08/23 02/08 14:59 02/08/23 14:59 STLFF Stillfront Group $1.77 / + (+0.00%) Berenberg analyst Edward… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Street Research STLFF Stillfront Group $1.77 / + (+0.00%) 01/10/23 Goldman Sachs Stillfront Group downgraded to Neutral from Buy at Goldman Sachs 10/12/22 Kepler Cheuvreux Stillfront Group upgraded to Hold from Reduce at Kepler Cheuvreux 10/11/22 Barclays Stillfront Group price target raised to SEK 31.50 from SEK 30.50 at Barclays 09/16/22 Barclays Stillfront Group price target lowered to SEK 30.50 from SEK 40 at Barclays
Recommendations	Scor price target raised to EUR 29.50 from EUR 28 at Berenberg » 14:59 02/08/23 02/08 14:59 02/08/23 14:59 SCRYY Scor $2.40 / +0.16 (+7.14%) Berenberg analyst Michael… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Street Research Events SCRYY Scor $2.40 / +0.16 (+7.14%) 01/18/23 JPMorgan Scor price target raised to EUR 18 from EUR 16.50 at JPMorgan 01/13/23 Exane BNP Paribas Scor reinitiated with an Outperform at Exane BNP Paribas 01/10/23 Deutsche Bank Scor price target raised to EUR 27 from EUR 25 at Deutsche Bank 11/22/22 Societe Generale Scor price target lowered to EUR 20 from EUR 21.50 at Societe Generale 03/02/23 Scor - SCRYY
Recommendations	Linea Directa price target lowered to EUR 0.95 from EUR 1.02 at Berenberg » 14:58 02/08/23 02/08 14:58 02/08/23 14:58 LNDAF Linea Directa $1.05 / + (+0.00%) Berenberg analyst Thomas… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial ShowHide Related Items >><< Street Research LNDAF Linea Directa $1.05 / + (+0.00%) 01/05/23 Berenberg Linea Directa downgraded to Hold from Buy at Berenberg 02/23/22 Berenberg Linea Directa price target raised to EUR 2.06 from EUR 2.03 at Berenberg 02/11/22 Berenberg Linea Directa price target raised to EUR 2.03 from EUR 2.01 at Berenberg

Events

Earnings calls, analyst events, roadshows and more

WYNN
Today at 16:15

Wynn Resorts - WYNN Conference Calls
FORM
Today at 16:25

FormFactor - FORM Conference Calls
UTI
Today at 16:30

Universal Technical - UTI Conference Calls
ME
Today at 16:30

23andMe - ME Conference Calls
TTMI
Today at 16:30

TTM Technologies - TTMI Conference Calls
DIS
Today at 16:30

Disney - DIS Conference Calls
VKTX
Today at 16:30

Viking Therapeutics - VKTX Conference Calls
AEIS
Today at 16:30

Advanced Energy - AEIS Conference Calls
INFA
Today at 16:30

Informatica - INFA Conference Calls
VNDA
Today at 16:30

Vanda Pharmaceuticals - VNDA Conference Calls

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Syndicate

This week’s upcoming IPOs and secondary offerings

Priced
Not Priced

Mon	BLNK X BLNK Blink Charging Spot Secondary Managers: Barclays Priced at: $12.00 8.333M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial
Tues	CVAC X CVAC CureVac Secondary Managers: Goldman Sachs, Jefferies, SVB Securities & Kempen Priced at: $9.25 27.027M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial DT X DT Dynatrace Spot Secondary Managers: BofA Priced at: $45.55 15M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial FRC X FRC First Republic Spot Secondary Managers: BofA, JPMorgan, Goldman Sachs & Morgan Stanley Priced at: $140.00 2.5M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial LBPH X LBPH Longboard Pharmaceuticals Spot Secondary Managers: Evercore ISI & Cantor Fitzgerald Priced at: $4.00 5M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial RXST X RXST RxSight Spot Secondary Managers: BofA Priced at: $12.50 4M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial SINT X SINT Sintx Technologies Spot Secondary Managers: Maxim Priced at: $5.60 2.15M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial STAF X STAF Staffing 360 Solutions Spot Secondary Managers: H.C. Wainwright Priced at: $2.65 1.88M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial TMCI X TMCI Treace Medical Spot Secondary Managers: BTIG Priced at: $21.00 4.76M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial XPOF X XPOF Xponential Fitness Spot Secondary Managers: BofA & Jefferies Priced at: $24.50 5M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial
Wed	SONN X SONN Sonnet BioTherapeutics Secondary Managers: Chardan & EF Hutton Priced at: $1.08 13.89M Shares
Thurs	No deals
Fri	No deals

Mon	No deals
Tues	No deals
Wed	BFRG X BFRG Bullfrog AI IPO Managers: WallachBeth, Kingswood $6.50 1.32M Shares HSAI X HSAI Hesai IPO Managers: Goldman Sachs, Morgan Stanley & Credit Suisse, Huatai Securities $17.00 - 19.00 9M Shares INTS X INTS Intensity Therapeutics IPO Managers: Benchmark $4.00-4.50 1.778M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial NRXS X NRXS Neuraxis IPO Managers: Alexander Capital $7.00-9.00 1.875M Shares NXT X NXT Nextracker IPO Managers: JPMorgan, BofA, Citi & Barclays, Truist, HSBC, BNP Paribas, Mizuho, Scotiabank, KeyBanc $20.00-23.00 23.26M Shares Special Comments Ratings Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial
Thurs	ENLT X ENLT Enlight Renewable Energy IPO Managers: JPMorgan, BofA & Barclays, Credit Suisse, Wolfe Research, Nomura, HSBC, Roth MKM $20.57 14M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial LEWY X LEWY LeeWay Services IPO Managers: ThinkEquity $5.00 1M Shares MLYS X MLYS Mineralys Therapeutics IPO Managers: BofA, Ever Bank, Stifel, Credit Suisse, Guggenheim & Wells Fargo $14.00-16.00 10M Shares Special Comments Some content is locked. Log in above or sign up for a free trial to see this information. Get Free Trial
Fri	No deals

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Natera publishes experience study in twin pregnancies in Prenatal Diagnosis

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