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2023-03-29 13:27:23 BLUE Bluebird Bio $3.15 / -1.155 (-26.86%) , CRSP Crispr Therapeutics $44.65 / +0.68 (+1.55%) … 13:27 03/29/23 03/29 13:27 03/29/23 13:27	Bluebird Bio reaction to lovo-cel BLA delay 'overdone,' says Raymond James Raymond James analyst Dane Leone makes no change to the firm's Outperform rating and $10 price target on Bluebird Bio (BLUE) shares after the company reported Q4 results and announced a delay for the lovo-cel BLA submission that had been expected in Q1. The concern is that the BLA submission delay presents launch timing risk given the competitive dynamics with exa-cel in SCD from Crispr Therapeutics (CRSP) and Vertex Pharmaceuticals (VRTX), but the firm thinks that the lovo-cel CMC issues "seem straight forward" and does not think the MDS case presents new issues with approvability, calling the current negative stock reaction "overdone." BLUE Bluebird Bio $3.15 / -1.155 (-26.86%) CRSP Crispr Therapeutics $44.65 / +0.68 (+1.55%) VRTX Vertex Pharmaceuticals $314.21 / +1.01 (+0.32%)	29 Mar 03 Apr 19 Jan

2023-03-29 13:27:23

BLUE

Bluebird Bio

$3.15 / -1.155 (-26.86%)

, CRSP

Crispr Therapeutics

$44.65 / +0.68 (+1.55%)

… 13:27

03/29/23

03/29

13:27

03/29/23

13:27

Bluebird Bio reaction to lovo-cel BLA delay 'overdone,' says Raymond James

Raymond James analyst Dane Leone makes no change to the firm's Outperform rating and $10 price target on Bluebird Bio (BLUE) shares after the company reported Q4 results and announced a delay for the lovo-cel BLA submission that had been expected in Q1. The concern is that the BLA submission delay presents launch timing risk given the competitive dynamics with exa-cel in SCD from Crispr Therapeutics (CRSP) and Vertex Pharmaceuticals (VRTX), but the firm thinks that the lovo-cel CMC issues "seem straight forward" and does not think the MDS case presents new issues with approvability, calling the current negative stock reaction "overdone."

BLUE

Bluebird Bio

$3.15 / -1.155 (-26.86%)

CRSP

Crispr Therapeutics

$44.65 / +0.68 (+1.55%)

VRTX

Vertex Pharmaceuticals

$314.21 / +1.01 (+0.32%)

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OTHER BREAKING NEWS FROM THE FLY

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General news	Market Update: the weaker than expected ISM services and factory data » 12:40 06/05/23 06/05 12:40 06/05/23 12:40 $ECON Economic Data / + Market Update: the weaker… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return on Jun 8th, 12:40 Get Free Trial ShowHide Related Items >><< Company News Street Research Periodicals On The Fly Technical Analysis $ECON Economic Data / + 03/22/23 Senators Scott, Warren unveil bipartisan Fed oversight legislation 03/01/23 Einhorn says investors should be 'bearish on stocks and bullish on inflation' $ECON Economic Data / + $ECON Economic Data / + 05/25/23 Biden, McCarthy edging close to debt ceiling deal, Reuters reports 03/29/23 Powell did not 'predict' another rate hike in meeting, CNBC reports 03/08/23 Biden to propose 25% billionaire tax, Bloomberg says 03/08/23 Biden to propose 25% billionaire tax, Bloomberg says $ECON Economic Data / + 05/31/23 What You Missed On Wall Street On Wednesday 05/24/23 What You Missed On Wall Street On Wednesday 05/03/23 What You Missed On Wall Street On Wednesday 04/19/23 What You Missed On Wall Street On Wednesday $ECON Economic Data / + 03/22/23 Fed says 'additional policy firming may be appropriate'
Recommendations	Transat A.T. price target raised to C$3.50 from C$2.50 at CIBC » 12:37 06/05/23 06/05 12:37 06/05/23 12:37 TRZBF Transat A.T. $3.38 / +0.08 (+2.42%) CIBC raised the… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return on Jun 8th, 12:37 Get Free Trial ShowHide Related Items >><< Street Research TRZBF Transat A.T. $3.38 / +0.08 (+2.42%) 05/30/23 National Bank Transat A.T. price target raised to C$3.25 from C$3 at National Bank 05/30/23 TD Securities Transat A.T. price target raised to C$5 from C$4 at TD Securities 03/10/23 Desjardins Transat A.T. price target raised to C$4 from C$3.50 at Desjardins 03/10/23 Scotiabank Transat A.T. price target raised to C$2 from C$1.50 at Scotiabank
Options	Victoria's Secret put volume heavy and directionally bearish » 12:35 06/05/23 06/05 12:35 06/05/23 12:35 VSCO Victoria's Secret $18.55 / -1.625 (-8.05%) Bearish flow noted in… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return on Jun 8th, 12:35 Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings On The Fly Options VSCO Victoria's Secret $18.55 / -1.625 (-8.05%) 06/02/23 S&P DJI announces changes to S&P400 at open on 6/20 05/15/23 Greenlight Capital exits positions in Victoria's Secret, Funko 02/24/23 Victoria's Secret, PINK announce pilot of loyalty program 02/21/23 Victoria's Secret, Naomi Osaka launch first design collaboration VSCO Victoria's Secret $18.55 / -1.625 (-8.05%) 06/02/23 TD Cowen Victoria's Secret price target lowered to $21 from $45 at TD Cowen 06/02/23 Morgan Stanley Victoria's Secret price target lowered to $19 from $44 at Morgan Stanley 06/02/23 Wells Fargo Victoria's Secret price target lowered to $34 from $55 at Wells Fargo 06/02/23 Barclays Victoria's Secret price target lowered to $21 from $35 at Barclays VSCO Victoria's Secret $18.55 / -1.625 (-8.05%) 05/31/23 Victoria's Secret cuts FY23 revenue view to flat to down low single digits 05/31/23 Victoria's Secret sees Q2 EPS 10c-40c, consensus 88c 05/31/23 Victoria's Secret sees Q1 EPS 10c-40c, consensus 88c 05/31/23 Victoria's Secret reports Q1 adjusted EPS 28c, consensus 54c VSCO Victoria's Secret $18.55 / -1.625 (-8.05%) 06/01/23 What You Missed On Wall Street On Thursday 06/01/23 What You Missed On Wall Street This Morning 06/01/23 Fly Intel: Pre-market Movers 05/31/23 Fly Intel: After-Hours Movers VSCO Victoria's Secret $18.55 / -1.625 (-8.05%) 05/31/23 Victoria's Secret options imply 12.8% move in share price post-earnings 04/05/23 Victoria's Secret call volume above normal and directionally bullish 12/27/22 Victoria's Secret put volume heavy and directionally bearish 12/19/22 Unusually active option classes on open December 19th
Hot Stocks	Gilead: Trodelvy delivered meaningful improvement in median OS in study » 12:34 06/05/23 06/05 12:34 06/05/23 12:34 GILD Gilead $77.72 / -0.165 (-0.21%) Gilead Sciences announced… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return on Jun 8th, 12:34 Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings On The Fly Events Options GILD Gilead $77.72 / -0.165 (-0.21%) 11:28 Today Kite's Yescarta CAR T-cell therapy shows longer OS vs. SOC in study 06/03/23 Gilead, Arcus announce updated results from interim analysis of ARC-7 study 05/26/23 Gilead announces CHMP reccomendation for the use of Veklury 05/17/23 Gilead to present advances across its oncology pipeline at ASCO Annual Meeting GILD Gilead $77.72 / -0.165 (-0.21%) 06/02/23 Argus Gilead continues to make regulatory progress, says Argus 05/16/23 BMO Capital Gilead upgraded to Outperform from Market Perform at BMO Capital 04/28/23 Piper Sandler Gilead assumed with an Overweight at Piper Sandler 04/12/23 Morgan Stanley Gilead price target raised to $85 from $81 at Morgan Stanley GILD Gilead $77.72 / -0.165 (-0.21%) 05/15/23 Gilead: Arcus deal may reduce Gilead's FY23 GAAP and non-GAAP EPS by 2c 04/27/23 Gilead backs FY23 adjusted EPS view $6.60-$7.00, consensus $6.84 04/27/23 Gilead reports Q1 Biktarvy sales up 24% y/y 04/27/23 Gilead Sciences reports Q1 adjusted EPS $1.37, consensus $1.54 GILD Gilead $77.72 / -0.165 (-0.21%) 05/16/23 What You Missed On Wall Street On Tuesday 05/16/23 What You Missed On Wall Street This Morning 05/16/23 Street Wrap: Today's Top 15 Upgrades, Downgrades, Initiations 04/28/23 Street Wrap: Today's Top 15 Upgrades, Downgrades, Initiations 06/09/23 Biotechnology 06/07/23 Global Healthcare Conference GILD Gilead $77.72 / -0.165 (-0.21%) 05/25/23 Gilead call volume above normal and directionally bullish 05/03/23 Gilead call volume above normal and directionally bullish 04/27/23 Gilead options imply 3.8% move in share price post-earnings 02/03/23 Early notable gainers among liquid option names on February 3rd
General news	May investor movement index 5.12 12:33 06/05/23 06/05 12:33 06/05/23 12:33 $ECON Economic Data / + ShowHide Related Items >><< Company News Street Research Periodicals On The Fly Technical Analysis $ECON Economic Data / + 03/22/23 Senators Scott, Warren unveil bipartisan Fed oversight legislation 03/01/23 Einhorn says investors should be 'bearish on stocks and bullish on inflation' $ECON Economic Data / + $ECON Economic Data / + 05/25/23 Biden, McCarthy edging close to debt ceiling deal, Reuters reports 03/29/23 Powell did not 'predict' another rate hike in meeting, CNBC reports 03/08/23 Biden to propose 25% billionaire tax, Bloomberg says 03/08/23 Biden to propose 25% billionaire tax, Bloomberg says $ECON Economic Data / + 05/31/23 What You Missed On Wall Street On Wednesday 05/24/23 What You Missed On Wall Street On Wednesday 05/03/23 What You Missed On Wall Street On Wednesday 04/19/23 What You Missed On Wall Street On Wednesday $ECON Economic Data / + 03/22/23 Fed says 'additional policy firming may be appropriate'
Hot Stocks	Tesla 'happy' to license Autopilot/FSD or other Tesla technology, says Elon Musk » 12:31 06/05/23 06/05 12:31 06/05/23 12:31 TSLA Tesla $218.16 / +4.19 (+1.96%) Tesla CEO Elon Musk said… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return on Jun 8th, 12:31 Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings Periodicals On The Fly Options TSLA Tesla $218.16 / +4.19 (+1.96%) 06/02/23 GM says every new EV product is more fuel-efficient and more cost-effective 06/02/23 GM CEO says Tesla has cost advantage in EVs over other car makers 05/25/23 Ford EV customers to gain access to 12,000 Tesla superchargers 05/25/23 Ford, Tesla CEOs to host Twitter Spaces chat on accelerating EV adoption TSLA Tesla $218.16 / +4.19 (+1.96%) 08:45 Today Citi Tesla price target raised to $215 from $175 at Citi 05/30/23 Roth MKM Ford access to Tesla charger network positive for entire space, says Roth MKM 05/30/23 Wedbush Musk visits China at key point for Tesla with price wars underway, says Wedbush 05/30/23 Barclays Tesla must address model concentration, says Barclays TSLA Tesla $218.16 / +4.19 (+1.96%) 04/19/23 Tesla reports Q1 EPS 85c, consensus 85c 04/19/23 Notable companies reporting after market close 03/02/23 Aehr Test Systems reiterates annual guidance, comments on Tesla statements 01/25/23 Tesla reports Q4 EPS $1.19, consensus $1.13 TSLA Tesla $218.16 / +4.19 (+1.96%) 06/01/23 Investors accuse Musk of insider trading in Dogecoin lawsuit, Reuters reports 06/01/23 Tesla is opening its charging network to rival vehicles, FT reports 05/31/23 Tesla to give early glimpse of updated Model 3 in Shanghai, Bloomberg says 05/30/23 Tesla won't have to recall vehicles over Passenger Play feature, Verge says TSLA Tesla $218.16 / +4.19 (+1.96%) 10:52 Today What You Missed This Week in EVs and Clean Energy 06/02/23 Here's What You Missed in Crypto This Week 06/01/23 What You Missed On Wall Street This Morning 05/31/23 What You Missed On Wall Street On Wednesday TSLA Tesla $218.16 / +4.19 (+1.96%) 09:55 Today Early notable gainers among liquid option names on June 5th 08:55 Today Notable open interest changes for June 5th 06/02/23 Notable open interest changes for June 2nd 05/31/23 Notable open interest changes for May 31st
Downgrade	BofA double downgrades Epam Systems after surprising guidance cut » 12:31 06/05/23 06/05 12:31 06/05/23 12:31 EPAM Epam Systems $213.78 / -45.95 (-17.69%) BofA analyst Jason… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return on Jun 8th, 12:31 Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings On The Fly Options EPAM Epam Systems $213.78 / -45.95 (-17.69%) 12:00 Today Epam Systems falls -18.1% 10:00 Today Epam Systems falls -16.8% 09:47 Today Epam Systems falls -17.2% 05/15/23 Lone Pine boosts Salesforce stake, reduces Visa, Mastercard stakes EPAM Epam Systems $213.78 / -45.95 (-17.69%) 12:26 Today BofA Epam Systems downgraded to Underperform from Buy at BofA 05/08/23 Susquehanna Epam Systems price target lowered to $350 from $410 at Susquehanna 05/08/23 TD Cowen Epam Systems price target lowered to $290 from $323 at TD Cowen 05/07/23 Barclays Epam Systems price target lowered to $310 from $380 at Barclays EPAM Epam Systems $213.78 / -45.95 (-17.69%) 06:20 Today Epam Systems cuts FY23 EPS view to $9.80-$10.20 from $10.60-$10.80 06:15 Today Epam Systems cuts Q2 EPS view to $2.33-$2.40 from $2.38-$2.46, consensus $2.41 05/05/23 Epam Systems cuts FY23 EPS view to $10.60-$10.80 from $11.15-$11.35 05/05/23 Epam Systems sees Q2 EPS $2.38-$2.46, consensus $2.48 EPAM Epam Systems $213.78 / -45.95 (-17.69%) 12:00 Today What You Missed On Wall Street This Morning 09:03 Today Fly Intel: Pre-market Movers EPAM Epam Systems $213.78 / -45.95 (-17.69%) 01/03/23 Unusual call flow in option market yesterday
Conference/Events	Savara management to meet with Piper Sandler » 12:30 06/05/23 06/05 12:30 06/05/23 12:30 SVRA Savara $2.94 / +0.04 (+1.38%) Dinner Meeting to be held… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return on Jun 8th, 12:30 Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings On The Fly Events SVRA Savara $2.94 / +0.04 (+1.38%) 03/10/23 Savara says exposure to Silicon Valley Bank immaterial 02/14/23 Savara announces Rob Lutz appointed COO, Wilhoit EVP Global Commercial 01/20/23 Savara announces new employment inducement grant SVRA Savara $2.94 / +0.04 (+1.38%) 05/16/23 Jefferies Savara assumed with Buy at Jefferies on 100% upside potential 05/16/23 Piper Sandler Piper Sandler sees 'ideal buying opportunity' into Savara data 05/16/23 Piper Sandler Piper Sandler sees 'deal buying opportunity' into Savara data 05/16/23 Jefferies Savara assumed with Buy from Hold at Jefferies SVRA Savara $2.94 / +0.04 (+1.38%) 05/15/23 Savara reports Q1 EPS (7c) vs, (7c)last year 03/30/23 Savara reports Q4 EPS (7c), consensus (7c) SVRA Savara $2.94 / +0.04 (+1.38%) 05/19/23 Biotech Alert: Searches spiking for these stocks today 01/05/23 Biotech Alert: Searches spiking for these stocks today 06/08/23 Savara 06/08/23 Savara Inc

Conference/Events	Teleflex management to meet with Piper Sandler » 12:28 06/05/23 06/05 12:28 06/05/23 12:28 TFX Teleflex $237.83 / +1.72 (+0.73%) Meeting to be held in… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return on Jun 8th, 12:28 Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings Events TFX Teleflex $237.83 / +1.72 (+0.73%) 06/01/23 Teleflex awarded two purchasing agreements from Premier healthcare 03/29/23 Teleflex signs supply agreement for staple line reinforcement material 03/13/23 Teleflex announces research data on the UroLift System 02/22/23 Teleflex announces key milestones in the release of two new catheters TFX Teleflex $237.83 / +1.72 (+0.73%) 05/30/23 CL King Teleflex initiated with a Buy at CL King 05/30/23 Morgan Stanley Teleflex assumed with an Equal Weight at Morgan Stanley 04/26/23 Wolfe Research Teleflex downgraded to Peer Perform from Outperform at Wolfe Research 04/18/23 Mizuho Teleflex price target raised to $250 from $220 at Mizuho TFX Teleflex $237.83 / +1.72 (+0.73%) 05/04/23 Teleflex backs FY23 adjusted EPS view $13.00-$13.60, consensus $13.29 05/04/23 Teleflex reports Q1 adjusted EPS $3.09, consensus $2.97 02/23/23 Teleflex sees 2023 adjusted EPS $13.00-$13.60, consensus $13.49 02/23/23 Teleflex reports Q4 adjusted EPS $3.52, consensus $3.44 06/07/23 Teleflex 06/08/23 Teleflex 06/09/23 Teleflex
Downgrade	Epam Systems downgraded to Underperform from Buy at BofA » 12:26 06/05/23 06/05 12:26 06/05/23 12:26 EPAM Epam Systems $213.10 / -46.63 (-17.95%) BofA analyst Jason… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return on Jun 8th, 12:26 Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings On The Fly Options EPAM Epam Systems $213.10 / -46.63 (-17.95%) 12:00 Today Epam Systems falls -18.1% 10:00 Today Epam Systems falls -16.8% 09:47 Today Epam Systems falls -17.2% 05/15/23 Lone Pine boosts Salesforce stake, reduces Visa, Mastercard stakes EPAM Epam Systems $213.10 / -46.63 (-17.95%) 05/08/23 Susquehanna Epam Systems price target lowered to $350 from $410 at Susquehanna 05/08/23 TD Cowen Epam Systems price target lowered to $290 from $323 at TD Cowen 05/07/23 Barclays Epam Systems price target lowered to $310 from $380 at Barclays 05/02/23 Stifel Epam Systems price target lowered to $350 from $407 at Stifel EPAM Epam Systems $213.10 / -46.63 (-17.95%) 06:20 Today Epam Systems cuts FY23 EPS view to $9.80-$10.20 from $10.60-$10.80 06:15 Today Epam Systems cuts Q2 EPS view to $2.33-$2.40 from $2.38-$2.46, consensus $2.41 05/05/23 Epam Systems cuts FY23 EPS view to $10.60-$10.80 from $11.15-$11.35 05/05/23 Epam Systems sees Q2 EPS $2.38-$2.46, consensus $2.48 EPAM Epam Systems $213.10 / -46.63 (-17.95%) 12:00 Today What You Missed On Wall Street This Morning 09:03 Today Fly Intel: Pre-market Movers EPAM Epam Systems $213.10 / -46.63 (-17.95%) 01/03/23 Unusual call flow in option market yesterday
Hot Stocks	Penske Automotive acquires Transolutions Truck Centres, terms not disclosed » 12:25 06/05/23 06/05 12:25 06/05/23 12:25 PAG Penske Automotive $142.92 / -3.455 (-2.36%) Penske Automotive Group… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return on Jun 8th, 12:25 Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings On The Fly Events PAG Penske Automotive $142.92 / -3.455 (-2.36%) 05/11/23 Penske Automotive authorizes additional security repurchase 05/11/23 Penske Automotive increases dividend 8% to 66c per share 02/17/23 Penske Automotive announces additional securities repurchase authority of $250M 01/25/23 Penske Automotive increases quarterly dividend by 7% to 61c per share PAG Penske Automotive $142.92 / -3.455 (-2.36%) 02/21/23 JPMorgan Penske Automotive price target raised to $135 from $130 at JPMorgan 02/09/23 Stephens Penske Automotive price target raised to $155 from $140 at Stephens 12/27/22 Morgan Stanley Used car prices still have room to decrease 'significantly,' says Morgan Stanley 10/06/22 JPMorgan Penske Automotive price target lowered to $110 from $125 at JPMorgan PAG Penske Automotive $142.92 / -3.455 (-2.36%) 04/26/23 Penske Automotive reports Q1 EPS $4.31, consensus $4.13 02/08/23 Penske Automotive reports Q4 EPS $4.21, consensus $3.95 PAG Penske Automotive $142.92 / -3.455 (-2.36%) 02/08/23 Fly Intel: Pre-market Movers 06/15/23 Penske Automotive
Options	UiPath call volume above normal and directionally bullish » 12:25 06/05/23 06/05 12:25 06/05/23 12:25 PATH UiPath $19.36 / +1.125 (+6.17%) Bullish option flow… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return on Jun 8th, 12:25 Get Free Trial ShowHide Related Items >><< Company News Street Research Earnings On The Fly Events Options PATH UiPath $19.36 / +1.125 (+6.17%) 05/31/23 Cathie Wood's ARK Investment bought 141.9M shares of UiPath today 05/25/23 Cathie Wood's ARK Investment bought 5M shares of UiPath today 05/25/23 UiPath falls -16.9% 05/25/23 UiPath falls -14.6% PATH UiPath $19.36 / +1.125 (+6.17%) 05/25/23 BMO Capital UiPath price target lowered to $18 from $20 at BMO Capital 05/25/23 DA Davidson DA Davidson sees large customer momentum at UiPath 05/25/23 Barclays UiPath price target lowered to $16 from $17 at Barclays 04/20/23 DA Davidson UiPath initiated with a Neutral at DA Davidson PATH UiPath $19.36 / +1.125 (+6.17%) 05/24/23 UiPath raises FY24 revenue view to $1.267B-$1.272B, consensus $1.25B 05/24/23 UiPath sees Q2 revnue$279M-$284M, consensus $283.9M 05/24/23 UiPath reports Q1 EPS 11c, consensus 2c 05/24/23 Notable companies reporting after market close PATH UiPath $19.36 / +1.125 (+6.17%) 05/25/23 What You Missed On Wall Street This Morning 05/24/23 Fly Intel: After-Hours Movers 03/16/23 What You Missed On Wall Street On Thursday 03/16/23 What You Missed On Wall Street This Morning 06/15/23 UiPath, Inc. PATH UiPath $19.36 / +1.125 (+6.17%) 06/02/23 UiPath call volume above normal and directionally bullish 06/02/23 Unusually active option classes on open June 2nd 06/01/23 Unusually active option classes on open June 1st 05/31/23 UiPath call volume above normal and directionally bullish
Technical Analysis	NASDAQ market internals summary » 12:17 06/05/23 06/05 12:17 06/05/23 12:17 $NSD NASDAQ Market Internals / + Volume is above average… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return on Jun 8th, 12:17 Get Free Trial ShowHide Related Items >><< Technical Analysis $NSD NASDAQ Market Internals / + 11:17 Today NASDAQ market internals summary 10:17 Today NASDAQ market internals summary 06/02/23 NASDAQ market internals summary 06/02/23 NASDAQ market internals summary

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