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CRSP Crispr Therapeutics $38.59 1.61 (4.35%) , VRTX Vertex $182.39 0.06 (0.03%) 11:33 04/16/19 04/16 11:33 04/16/19 11:33 Recommendations	Crispr Therapeutics, Vertex analyst commentary at Piper Jaffray » Piper reiterates $75… Piper reiterates $75 target for Crispr after CTX001 gets Fast Track. Piper Jaffray analyst Edward Tenthoff reiterates an Overweight rating on Crispr Therapeutics after the company and partner Vertex (VRTX) announced Fast Track Designation for CTX001 to treat transfusion-dependent beta thalassemia. The analyst believes Crispr's ex vivo approach and biological rational of targeting fetal hemoglobin "de-risk and differentiate" CTX001 from other gene editing players. And he continues to think that first-in-man CTX001 data this year "will serve as an important driver" for Crispr and the gene editing field. Tenthoff says Crispr Therapeutics remains a top for 2019. CRSP Crispr Therapeutics $38.59 1.61 (4.35%) VRTX Vertex $182.39 0.06 (0.03%) 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	30 Apr 14 May
CRSP Crispr Therapeutics $36.98 -0.92 (-2.43%) , VRTX Vertex $182.33 -0.36 (-0.20%) 07:20 04/16/19 04/16 07:20 04/16/19 07:20 Hot Stocks	Crispr Therapeutics, Vertex announce fast track designation for CTX001 from FDA » Crispr Therapeutics… Crispr Therapeutics (CRSP) and Vertex (VRTX) announced that the FDA has granted fast track designation for CTX001 for the treatment of transfusion-dependent beta thalassemia. CTX001 is an investigational, autologous, gene-edited hematopoietic stem cell therapy for patients suffering from severe hemoglobinopathies. CRSP Crispr Therapeutics $36.98 -0.92 (-2.43%) VRTX Vertex $182.33 -0.36 (-0.20%) 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	30 Apr 14 May
ABBV AbbVie $80.78 0.07 (0.09%) , ICPT Intercept $95.04 -9.71 (-9.27%) … 04:55 04/14/19 04/14 04:55 04/14/19 04:55 Conference/Events	European Association for the Study of the Liver to hold a meeting » EASL International Liver… EASL International Liver Congress 2019 will be held in Vienna, Austria on April 10-14. ABBV AbbVie $80.78 0.07 (0.09%) ICPT Intercept $95.04 -9.71 (-9.27%) VRTX Vertex $182.69 -2.4 (-1.30%) GILD Gilead $65.27 -1.04 (-1.57%) AGN Allergan $144.94 -0.08 (-0.06%) GNFT Genfit $24.84 -0.02 (-0.08%) ALNY Alnylam $89.78 1.68 (1.91%) APEN Apollo Endosurgery $3.43 -0.025 (-0.72%) BMY Bristol-Myers $45.58 -0.52 (-1.13%) CBAY CymaBay $12.50 -0.6 (-4.58%) CTSO CytoSorbents $7.16 -0.28 (-3.76%) EIGR Eiger BioPharmaceuticals $14.25 -0.04 (-0.28%) ENTA Enanta $92.32 0.42 (0.46%) NDRA ENDRA Life Sciences $1.51 (0.00%) IPSEY Ipsen $0.00 (0.00%) MYRG MYR Group $36.36 -0.14 (-0.38%) NVS Novartis $80.26 -1.615 (-1.97%) NVO Novo Nordisk $50.21 -0.74 (-1.45%) OSUR OraSure $10.12 -0.12 (-1.17%) SIEGY Siemens $0.00 (0.00%) JNJ Johnson & Johnson $136.00 0.72 (0.53%) SBPH Spring Bank Pharmaceuticals $9.54 -0.29 (-2.95%) 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	16 Apr 17 Apr 24 Apr 25 Apr 25 Apr 25 Apr 25 Apr 25 Apr 30 Apr 01 May 02 May 03 May 06 May 07 May 08 May 08 May 08 May 18 May 20 May 21 May 21 May 21 May 28 May 29 May 05 Jun 06 Aug 13 Nov
ABBV AbbVie $80.78 0.07 (0.09%) , ICPT Intercept $95.04 -9.71 (-9.27%) … 04:55 04/13/19 04/13 04:55 04/13/19 04:55 Conference/Events	European Association for the Study of the Liver to hold a meeting » EASL International Liver… EASL International Liver Congress 2019 will be held in Vienna, Austria on April 10-14. ABBV AbbVie $80.78 0.07 (0.09%) ICPT Intercept $95.04 -9.71 (-9.27%) VRTX Vertex $182.69 -2.4 (-1.30%) GILD Gilead $65.27 -1.04 (-1.57%) AGN Allergan $144.94 -0.08 (-0.06%) GNFT Genfit $24.84 -0.02 (-0.08%) ALNY Alnylam $89.78 1.68 (1.91%) APEN Apollo Endosurgery $3.43 -0.025 (-0.72%) BMY Bristol-Myers $45.58 -0.52 (-1.13%) CBAY CymaBay $12.50 -0.6 (-4.58%) CTSO CytoSorbents $7.16 -0.28 (-3.76%) EIGR Eiger BioPharmaceuticals $14.25 -0.04 (-0.28%) ENTA Enanta $92.32 0.42 (0.46%) NDRA ENDRA Life Sciences $1.51 (0.00%) IPSEY Ipsen $0.00 (0.00%) MYRG MYR Group $36.36 -0.14 (-0.38%) NVS Novartis $80.26 -1.615 (-1.97%) NVO Novo Nordisk $50.21 -0.74 (-1.45%) OSUR OraSure $10.12 -0.12 (-1.17%) SIEGY Siemens $0.00 (0.00%) JNJ Johnson & Johnson $136.00 0.72 (0.53%) SBPH Spring Bank Pharmaceuticals $9.54 -0.29 (-2.95%) 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	13 Apr 16 Apr 17 Apr 24 Apr 25 Apr 25 Apr 25 Apr 25 Apr 25 Apr 30 Apr 01 May 02 May 03 May 06 May 07 May 08 May 08 May 08 May 18 May 20 May 21 May 21 May 21 May 28 May 29 May 05 Jun 06 Aug 13 Nov
ABBV AbbVie $81.78 -1.17 (-1.41%) , ICPT Intercept $104.75 -15.78 (-13.09%) … 04:55 04/12/19 04/12 04:55 04/12/19 04:55 Conference/Events	European Association for the Study of the Liver to hold a meeting » EASL International Liver… EASL International Liver Congress 2019 will be held in Vienna, Austria on April 10-14. ABBV AbbVie $81.78 -1.17 (-1.41%) ICPT Intercept $104.75 -15.78 (-13.09%) VRTX Vertex $185.09 -5.27 (-2.77%) GILD Gilead $66.31 -1.1 (-1.63%) AGN Allergan $145.02 -1.13 (-0.77%) GNFT Genfit $24.86 -0.27 (-1.07%) ALNY Alnylam $88.10 -2.74 (-3.02%) APEN Apollo Endosurgery $3.46 (0.00%) BMY Bristol-Myers $46.10 0.21 (0.46%) CBAY CymaBay $13.10 -0.05 (-0.38%) CTSO CytoSorbents $7.44 0.09 (1.22%) EIGR Eiger BioPharmaceuticals $14.29 -0.28 (-1.92%) ENTA Enanta $91.90 -2.85 (-3.01%) NDRA ENDRA Life Sciences $1.51 -0.01 (-0.66%) IPSEY Ipsen $0.00 (0.00%) MYRG MYR Group $36.50 0.24 (0.66%) NVS Novartis $81.87 -0.04 (-0.05%) NVO Novo Nordisk $50.95 -0.2 (-0.39%) OSUR OraSure $10.24 -0.14 (-1.35%) SIEGY Siemens $0.00 (0.00%) JNJ Johnson & Johnson $135.28 -0.33 (-0.24%) SBPH Spring Bank Pharmaceuticals $9.83 -0.06 (-0.61%) 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	12 Apr 13 Apr 16 Apr 17 Apr 24 Apr 25 Apr 25 Apr 25 Apr 25 Apr 25 Apr 01 May 02 May 03 May 06 May 07 May 08 May 08 May 18 May 20 May 21 May 21 May 21 May 28 May 05 Jun 13 Nov

VRTX Vertex $185.09 -5.27 (-2.77%) 16:50 04/11/19 04/11 16:50 04/11/19 16:50 Initiation	Vertex initiated at Evercore ISI » Vertex initiated with an… Vertex initiated with an In Line at Evercore ISI. Evercore ISI analyst Ravi Mehrotra initiated Vertex with an In-Line rating and a price target of $183. The analyst says the company has "great science, execution, and management", but its multiple is the highest relative to its peers and appears to be "priced to perfection". Mehrotra adds that the debate around EU pricing will intensify, becoming a "bigger and longer headwind". 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial
ABBV AbbVie $82.95 0.27 (0.33%) , ICPT Intercept $120.53 2.18 (1.84%) … 04:55 04/11/19 04/11 04:55 04/11/19 04:55 Conference/Events	European Association for the Study of the Liver to hold a meeting » EASL International Liver… EASL International Liver Congress 2019 will be held in Vienna, Austria on April 10-14. ABBV AbbVie $82.95 0.27 (0.33%) ICPT Intercept $120.53 2.18 (1.84%) VRTX Vertex $190.36 2.06 (1.09%) GILD Gilead $67.41 1.32 (2.00%) AGN Allergan $146.15 -1.3 (-0.88%) GNFT Genfit $25.13 -0.3 (-1.18%) ALNY Alnylam $90.84 2.07 (2.33%) APEN Apollo Endosurgery $3.46 0.175 (5.34%) BMY Bristol-Myers $45.89 -0.1 (-0.22%) CBAY CymaBay $13.15 0.21 (1.62%) CTSO CytoSorbents $7.35 -0.17 (-2.26%) EIGR Eiger BioPharmaceuticals $14.57 -0.31 (-2.08%) ENTA Enanta $94.75 2.28 (2.47%) NDRA ENDRA Life Sciences $1.52 -0.05 (-3.18%) IPSEY Ipsen $0.00 (0.00%) MYRG MYR Group $36.26 0.66 (1.85%) NVS Novartis $81.91 -1.49 (-1.79%) NVO Novo Nordisk $51.15 -0.005 (-0.01%) OSUR OraSure $10.38 -0.19 (-1.80%) SIEGY Siemens $0.00 (0.00%) JNJ Johnson & Johnson $135.61 -0.01 (-0.01%) SBPH Spring Bank Pharmaceuticals $9.89 -0.06 (-0.60%) 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	11 Apr 12 Apr 13 Apr 16 Apr 17 Apr 24 Apr 25 Apr 25 Apr 25 Apr 25 Apr 25 Apr 01 May 02 May 03 May 06 May 07 May 08 May 08 May 18 May 20 May 21 May 21 May 21 May 28 May 05 Jun 13 Nov
ABBV AbbVie $82.68 -1.3 (-1.55%) , ICPT Intercept $118.35 -1.84 (-1.53%) … 08:13 04/10/19 04/10 08:13 04/10/19 08:13 Conference/Events	European Association for the Study of the Liver to hold a meeting » EASL International Liver… EASL International Liver Congress 2019 will be held in Vienna, Austria on April 10-14. ABBV AbbVie $82.68 -1.3 (-1.55%) ICPT Intercept $118.35 -1.84 (-1.53%) VRTX Vertex $188.30 -0.63 (-0.33%) GILD Gilead $66.09 -1.28 (-1.90%) AGN Allergan $147.45 -3.04 (-2.02%) GNFT Genfit $25.43 -0.2 (-0.78%) ALNY Alnylam $88.77 -1.4 (-1.55%) APEN Apollo Endosurgery $3.28 (0.00%) BMY Bristol-Myers $45.99 -0.76 (-1.63%) CBAY CymaBay $12.94 -0.54 (-4.01%) CTSO CytoSorbents $7.52 0.02 (0.27%) EIGR Eiger BioPharmaceuticals $14.88 -0.08 (-0.53%) ENTA Enanta $92.47 0.03 (0.03%) NDRA ENDRA Life Sciences $1.57 0.02 (1.29%) IPSEY Ipsen $0.00 (0.00%) MYRG MYR Group $35.60 -0.37 (-1.03%) NVS Novartis $83.40 -11.515 (-12.13%) NVO Novo Nordisk $51.16 -0.205 (-0.40%) OSUR OraSure $10.57 -0.29 (-2.67%) SIEGY Siemens $0.00 (0.00%) JNJ Johnson & Johnson $135.62 -0.51 (-0.37%) SBPH Spring Bank Pharmaceuticals $9.95 -0.56 (-5.33%) 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	10 Apr 10 Apr 12 Apr 13 Apr 16 Apr 17 Apr 24 Apr 25 Apr 25 Apr 25 Apr 25 Apr 25 Apr 01 May 02 May 03 May 06 May 07 May 08 May 08 May 18 May 20 May 21 May 21 May 21 May 28 May 05 Jun 13 Nov
VRTX Vertex $186.01 2.15 (1.17%) 08:04 04/02/19 04/02 08:04 04/02/19 08:04 Hot Stocks	Vertex appoints Charles Wagner as EVP, CFO » Vertex Pharmaceuticals… Vertex Pharmaceuticals announced the appointment of Charles Wagner as EVP and CFO, effective April 10, 2019. Mr. Wagner will report directly to Vertex chairman, president and CEO Jeffrey Leiden and oversee the finance, internal audit, investor relations, and global security and facilities functions. Wagner joins Vertex from Ortho Clinical Diagnostics, where he served as CFO and EVP, Finance. 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	10 Apr
NVDA Nvidia $179.20 5.395 (3.10%) , CRTO Criteo $18.85 -3.14 (-14.28%) … 11:14 03/26/19 03/26 11:14 03/26/19 11:14 On The Fly	Nvidia initiation, Criteo downgrades among today's top analyst calls » Check out today's top… Open Full Text NVDA Nvidia $179.20 5.395 (3.10%) CRTO Criteo $18.85 -3.14 (-14.28%) GOOG Alphabet $1,192.81 0.09 (0.01%) GOOGL Alphabet Class A $1,196.70 -0.43 (-0.04%) CMCM Cheetah Mobile $6.56 -0.45 (-6.42%) VRTX Vertex $188.47 4.57 (2.49%) PTI Proteostasis $1.34 0.02 (1.52%) BBBY Bed Bath & Beyond $17.86 3.99 (28.77%) 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	27 Mar 04 Apr 10 Apr 10 Apr 29 Apr 29 Apr 27 Oct

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