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HCM

Hutchison China MediTech

$13.81

-0.015 (-0.11%)

14:56
01/16/17
01/16
14:56
01/16/17
14:56

Hutchison China MediTech reports data from fruquintinib, paclitaxel trial

Hutchison China MediTech announced that data from the ongoing Phase I/II clinical trial of fruquintinib in combination with paclitaxel, or Taxol, in second-line patients with advanced gastric cancer will be presented at the 2017 Gastrointestinal Cancers Symposium. Giving an abstract of the trial results, the company stated that as of September 10, 2016, a total of 32 patients were enrolled and dosed with fruquintinib in combination with weekly paclitaxel. The recommended phase II dose of fruquintinib was determined to be 4mg daily. Two patients at 4mg experienced dose-limiting toxicity, both with febrile neutropenia. Grade 3 or 4 treatment emergent adverse events included neutropenia at 40.6% and leukopenia at 28.1%, with higher frequencies in the 4mg cohort as compared with lower doses. At steady state, fruquintinib drug exposure increased dose-proportionally and was within the same range as given as a single agent. Paclitaxel exposure at fruquintinib RP2D however, increased by approximately 30% as compared to that of single agent. Twenty eight of 32 patients were evaluable for tumor response, and of these, 10 patients achieved confirmed partial response -- objective response rate 35.7% -- and 9 patients experienced stable disease for at least 8 weeks -- disease control rate 67.9%.

HCM Hutchison China MediTech
$13.81

-0.015 (-0.11%)

04/11/16
STFL
04/11/16
INITIATION
Target $18
STFL
Buy
Hutchison China MediTech initiated with a Buy at Stifel
Target $18.
04/11/16
ADAM
04/11/16
INITIATION
Target $20
ADAM
Buy
Hutchison China MediTech initiated with a Buy at Canaccord
Target $20.
04/11/16
BOFA
04/11/16
INITIATION
Target $16
BOFA
Buy
Hutchison China MediTech initiated with a Buy at BofA/Merrill
Target $16.
04/11/16
04/11/16
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Dycom (DY) initiated with an Overweight due to the company's position to benefit over multiple years as telecommunications and cable companies deploy large amounts of capital to upgrade their infrastructure to meet the increasing data demands of their customers. 2. FuelCell (FCEL) initiated with a Buy at Roth Capital by analyst Craig Irwin, who said the company is the "premiere provider of clean distributed generation solutions." 3. MicroStrategy (MSTR) initiated with a Buy at Citi with analyst Walter Pritchard saying the company offers the best way to invest in the trend of data analytics "getting in the hands of a broadening population of business users." 4. Western Digital (WDC) initiated with a Market Perform at Cowen by analyst Karl Ackerman, who cited cautious near-term fundamentals as the SanDisk (SNDK) transaction could pressure earnings. 5. Hutchison China MediTech (HCM) initiated with a Buy at BofA/Merrill, Canaccord and Stifel. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

SECO

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RBS

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General Electric

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BRFS

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SU

Suncor

$35.42

0.2 (0.57%)

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  • 05

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SAP

SAP

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-1.44 (-1.25%)

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FB

Facebook

$180.87

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CSX

CSX

$51.01

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AYTU

Aytu BioScience

$3.03

0.4301 (16.54%)

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EPIX

ESSA Pharma

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MRDN

Meridian Waste Solutions

$1.69

0.0101 (0.60%)

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APD

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BOOT

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SD

SandRidge Energy

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SYMC

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NRIM

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