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AZN

AstraZeneca

$33.97

-0.055 (-0.16%)

12:37
05/19/17
05/19
12:37
05/19/17
12:37

AstraZeneca announces positive CHMP opinion for brodalumab

AstraZeneca announced that its partner LEO Pharma has received a positive opinion from the Committee for Medicinal Products for Human Us eof the European Medicines Agency recommending the approval of brodalumab for the treatment of adult patients with moderate-to-severe plaque psoriasis who are candidates for systemic therapy. Brodalumab is the first and only fully human monoclonal antibody that selectively targets the IL-17 receptor. By binding to the receptor, brodalumab effectively blocks the biological activity of several pro-inflammatory IL-17 cytokines, which are important in psoriasis, a chronic, debilitating skin disease that causes red patches of skin covered with silvery scales. In July 2016, AstraZeneca announced an agreement granting LEO Pharma exclusive rights to develop and commercialise brodalumab in Europe. The announcement follows the approval of brodalumab by the US Food and Drug Administration in February 2017 and the approval by the Japanese Pharmaceuticals and Medical Devices Agency in 2016. The CHMP's positive opinion on brodalumab will now be reviewed by the European Commission, which has the authority to approve medicines for the European Union.The final decision is applicable to all EU and European Economic Area countries. Reference Link

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    Jun

AZN AstraZeneca
$33.97

-0.055 (-0.16%)

05/17/17
JPMS
05/17/17
UPGRADE
Target $72
JPMS
Overweight
Clovis upgraded to Overweight from Neutral at JPMorgan
JPMorgan analyst Cory Kasimov upgraded Clovis Oncology (CLVS) to Overweight and raised his price target for the shares to $72 from $58. The stock closed yesterday up 2%, or $1.05, to $49.56. The shares are down 35% over the last two months for "no clear fundamental reason," Kasimov tells investors in a research note. The analyst is "increasingly comfortable" recommending Clovis ahead of its Phase 3 study evaluating Rubraca in maintenance ovarian cancer now that more PARP class data has emerged. He has not seen "convincing evidence" that there is a clear efficacy difference between Clovis' rucaparib, Tesaro's (TSRO) niraparib and AstraZeneca's (AZN) olaparib.
05/16/17
LEER
05/16/17
NO CHANGE
Target $36
LEER
Outperform
AstraZeneca price target raised to $36 from $33 at Leerink
Leerink analyst Seamus Fernandez raised his price target for AstraZeneca to $36 after hosting a call with a lung cancer specialist. The specialist believes that once approved, the uptake of AstraZeneca's Imfinzi in Stage III unresectable non-small cell lung cancer will be "significant" given the poor outcomes and general lack of an effective treatment standard in this setting, Fernandez tells investors in a research note. The analyst raised his peak worldwide forecasts for the drug by $1B and keeps an Outperform rating on AstraZeneca.
05/15/17
LEER
05/15/17
NO CHANGE
LEER
GlaxoSmithKline possible move to buyout Novartis stake makes sense, says Leerink
Leerink analyst Seamus Fernandez is not surprised by the news that GlaxoSmithKline (GSK) may buyout Novartis' (NVS) 36.5% stake in its Consumer Healthcare joint venture through a GBP8B deal sooner rather than later. The analyst believes this buyout could be beneficial as the infusion of additional cash from the buyout could bolster Novartis appetite for large scale M&A, including companies such as AstraZeneca (AZN) whose immune-oncology assets could complement its small-molecule focused oncology portfolio, according to the London Times.
05/12/17
05/12/17
UPGRADE

Neutral
AstraZeneca upgraded to Neutral at Credit Suisse
As previously reported, Credit Suisse analyst Rebekah Harper upgraded AstraZeneca to Neutral from Underperform after the company reported surprise positive headline results from the Phase 3 PACIFIC trial for Imfinzi in stage 3 unresectable lung cancer in all-comers, with positive progression free survival data. The analyst believes that AstraZeneca is in a "unique position" with this indication, with a likely two to three years lead versus competitors, as other P3s are not due until 2020+. Harper expects U.S. approval for AstraZeneca in this indication before the end of 2017.

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FIT

Fitbit

$5.61

-0.15 (-2.60%)

08:45
07/24/17
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08:45
Options
Largest borrow rate increases among liquid names »

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SPI

SPI Energy

$0.54

-0.047 (-8.01%)

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SPI Energy says Nasdaq grants request to extend stay of suspension in trading »

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IBIO

iBio

$0.32

-0.006 (-1.82%)

08:43
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iBio enters into stock purchase agreement for up to $16M with LPC »

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CYTX

Cytori Therapeutics

$1.11

-0.01 (-0.89%)

08:43
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08:43
Conference/Events
Cytori Therapeutics to hold a conference call »

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BOH

Bank of Hawaii

$81.45

-0.52 (-0.63%)

08:42
07/24/17
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08:42
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08:42
Earnings
Bank of Hawaii reports Q2 EPS $1.05, consensus $1.03 »

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  • 24

    Jul

JCP

J.C. Penney

$5.08

0.08 (1.60%)

, AAPL

Apple

$150.27

-0.07 (-0.05%)

08:40
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08:40
Hot Stocks
J.C. Penney now accepts Apple Pay at all stores »

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JCP

J.C. Penney

$5.08

0.08 (1.60%)

AAPL

Apple

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-0.07 (-0.05%)

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  • 01

    Aug

WWD

Woodward

$68.55

-0.87 (-1.25%)

08:39
07/24/17
07/24
08:39
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08:39
Conference/Events
Woodward management to meet with Oppenheimer »

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SILC

Silicom

$51.37

0.96 (1.90%)

08:38
07/24/17
07/24
08:38
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08:38
Conference/Events
Silicom management to meet with Needham »

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  • 01

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OTIV

On Track Innovations

$1.47

0.025 (1.74%)

08:38
07/24/17
07/24
08:38
07/24/17
08:38
Hot Stocks
On Track Innovations' Uno-8 contactless reader granted EMVCo Modular approval »

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  • 09

    Aug

FNJN

Finjan Holdings

08:38
07/24/17
07/24
08:38
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08:38
Hot Stocks
Finjan Holdings says oral arguments to be heard at Court of Appeals on Sep. 8 »

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POL

PolyOne

$38.46

-0.18 (-0.47%)

08:37
07/24/17
07/24
08:37
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08:37
Conference/Events
PolyOne management to meet with Northcoast »

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  • 01

    Aug

ARNC

Arconic

$25.21

0.46 (1.86%)

08:37
07/24/17
07/24
08:37
07/24/17
08:37
Earnings
Arconic sees FY17 EPS $1.15-$1.20, consensus $1.16 »

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  • 24

    Jul

HIFR

InfraREIT

$19.90

0.2 (1.02%)

08:37
07/24/17
07/24
08:37
07/24/17
08:37
Hot Stocks
Breaking Hot Stocks news story on InfraREIT 

InfraREIT trading resumes…

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  • 02

    Aug

SLB

Schlumberger

$66.53

-0.49 (-0.73%)

08:36
07/24/17
07/24
08:36
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08:36
Recommendations
Schlumberger analyst commentary  »

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MED

Medifast

$42.11

0.28 (0.67%)

08:36
07/24/17
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Medifast: Take Shape For Life rebrands to OPTAVIA »

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  • 08

    Aug

P

Pandora

$9.47

0.33 (3.61%)

, AAPL

Apple

$150.27

-0.07 (-0.05%)

08:36
07/24/17
07/24
08:36
07/24/17
08:36
Periodicals
Spotify near new licensing pact with Warner Music, Reuters reports »

Spotify and Warner Music…

P

Pandora

$9.47

0.33 (3.61%)

AAPL

Apple

$150.27

-0.07 (-0.05%)

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  • 31

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  • 05

    Sep

HIFR

InfraREIT

$19.90

0.2 (1.02%)

08:35
07/24/17
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Hot Stocks
InfraREIT announces agreement regarding dismissal of pending rate case »

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  • 02

    Aug

DMPI

DelMar Pharmaceuticals

$2.08

0.11 (5.58%)

08:34
07/24/17
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08:34
Hot Stocks
DelMar Pharmaceuticals: HGRAC approves safety, efficacy study of VAL-083 »

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NVCR

Novocure

08:34
07/24/17
07/24
08:34
07/24/17
08:34
Conference/Events
Novocure management to meet with JMP Securities »

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  • 27

    Jul

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ALV

Autoliv

$106.78

-9.11 (-7.86%)

08:34
07/24/17
07/24
08:34
07/24/17
08:34
Recommendations
Autoliv analyst commentary  »

Autoliv has reached…

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  • 14

    Sep

LMAT

LeMaitre

$28.31

-0.89 (-3.05%)

08:33
07/24/17
07/24
08:33
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08:33
Conference/Events
LeMaitre management to meet with Craig Hallum »

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  • 27

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ARNC

Arconic

$25.21

0.46 (1.86%)

08:33
07/24/17
07/24
08:33
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08:33
Earnings
Arconic reports Q2 EPS ex-items 32c, consensus 26c »

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  • 24

    Jul

WU

Western Union

$19.09

0.01 (0.05%)

, BP

BP

$34.68

-0.42 (-1.20%)

08:33
07/24/17
07/24
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Hot Stocks
Western Union announces agreement with BP Australia »

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WU

Western Union

$19.09

0.01 (0.05%)

BP

BP

$34.68

-0.42 (-1.20%)

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  • 03

    Aug

GRA

W.R. Grace

$72.17

1.12 (1.58%)

08:33
07/24/17
07/24
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08:33
Conference/Events
W.R. Grace management to meet with Seaport Global »

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  • 27

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  • 01

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PFE

Pfizer

$33.48

-0.06 (-0.18%)

08:32
07/24/17
07/24
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Pfizer says Reflections B7391003 study met primary objective »

Pfizer announced that the…

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