Zosano Pharma presents additional data from ZOTRIP study
Zosano Pharma presented additional data from its pivotal Phase 2/3 ZOTRIP study evaluating M207 as an acute treatment for migraine during the 59th Annual Scientific Meeting of the American Headache Society in Boston, MA. The data were presented Saturday during the late-breaking session by Egilius Spierings, M.D., Ph.D., a clinical investigator for the study and a Clinical Professor of Neurology and Craniofacial Pain at Tufts University Schools of Medicine and Dental Medicine. As previously reported, the 3.8mg dose of M207 achieved both co-primary endpoints of pain freedom and most bothersome symptom freedom at 2 hours. In addition, the 3.8mg dose achieved significance in the secondary endpoints of pain freedom at 45 minutes and 1 hour and showed durability of effect on pain freedom at 24 and 48 hours. The data presented at AHS demonstrated that these results were attained with no SAEs and a favorable tolerability profile. M207 is designed to rapidly deliver zolmitriptan during a migraine attack utilizing Zosano's proprietary Adhesive Dermally-Applied Microarray, or ADAM technology. Zosano's ADAM technology consists of titanium microprojections coated with drug, and in the case of M207, our formulation of zolmitriptan. Our ADAM technology delivers zolmitriptan by abrading the stratum corneum and allowing drug to be absorbed into the microcapillary system of the skin.