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ICPT

Intercept

$135.03

5.47 (4.22%)

07:21
07/31/17
07/31
07:21
07/31/17
07:21

Intercept announces Phase 2 AESOP trial met primary endpoint

Intercept Pharmaceuticals announced that the Phase 2 AESOP trial evaluating obeticholic acid, or OCA, for the treatment of patients with primary sclerosing cholangitis, PSC, met its primary endpoint. Patients who initiated OCA 5 mg with the option to titrate to 10 mg achieved a statistically significant reduction in alkaline phosphatase, or ALP, as compared to placebo. AESOP is a 24-week, double-blind, placebo-controlled, dose-ranging trial evaluating the efficacy and safety of OCA compared to placebo in 77 patients with PSC, followed by a two-year long term safety extension, or LTSE, open-label phase which is currently ongoing. Patients were randomized to one of three treatment groups: placebo, OCA 1.5 - 3 mg, and OCA 5 - 10 mg. Approximately half the patients were receiving ursodeoxycholic acid, or UDCA, treatment at baseline and continued on a stable dose during the trial. The primary endpoint of the study was the change in ALP relative to placebo at week 24 for the OCA 5 - 10 mg group. Results for the intent-to-treat population are shown below.

  • 15

    Aug

ICPT Intercept
$135.03

5.47 (4.22%)

07/17/17
HCWC
07/17/17
NO CHANGE
Target $12
HCWC
Buy
CymaBay price target raised to $12 from $7 at H.C. Wainwright
H.C. Wainwright analyst Ed Arce raised his price target for CymaBay (CBAY) to $12 saying the Phase 2 results of seladelpar in primary biliary cholangitis "are more robust" than Intercept Pharmaceutical's (ICPT) Ocaliva. The analyst notes that his new target reflects increased confidence in the approvability and market potential of seladelpar. He has a Buy rating on CymaBay.
07/11/17
JEFF
07/11/17
NO CHANGE
JEFF
Jefferies fundamentally positive on Biotechnology, lists top picks
Jefferies analyst Michael Yee rolled out coverage of 12 Biotechnology names in a 550 page research report. The analyst is "fundamentally positive" on the sector, believing investor interest in large-caps will pick up "as the road to repair slowly continues." He believes the smid-cap space is "becoming a good stock-pickers' market." Yee's top picks in Biotech space include Celgene (CELG), Vertex (VRTX), Spark Therapeutics (ONCE), Prothena (PRTA) and Intercept (ICPT). The analyst's best picks in the smid-cap space are Spark, Prothena, Intercept and FibroGen (FGEN).
07/10/17
JEFF
07/10/17
INITIATION
Target $275
JEFF
Buy
Intercept initiated with a Buy at Jefferies
Jefferies initiated Intercept with a Buy and a $275 price target.
05/05/17
LDLW
05/05/17
UPGRADE
LDLW
Hold
Intercept upgraded to Hold from Sell at Laidlaw

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Deere

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Estee Lauder

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Paylocity announces Michael Haske's promotion to president & COO »

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ADP

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SN

Sanchez Energy

$4.87

-0.145 (-2.89%)

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Sanchez Energy to sell Javelina asset in Eagle Ford shale for about $105M »

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BABA

Alibaba

$163.92

4.42 (2.77%)

17:50
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Alibaba analyst commentary at Baird »

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ASYS

Amtech Systems

$10.14

-0.51 (-4.79%)

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Syndicate
Amtech Systems announces common stock offering, no amount given »

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CPCAY

Cathay Pacific

$7.47

0.15 (2.05%)

17:47
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17:47
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Cathay Pacific rating change at Goldman Sachs »

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RTN

Raytheon

$177.25

-0.83 (-0.47%)

17:32
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Hot Stocks
Raytheon awarded $104.8M government contract »

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SPWH

Sportsman's Warehouse

$3.46

-0.12 (-3.35%)

, GLOB

Globant

$42.26

-0.64 (-1.49%)

17:32
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Hot Stocks
On The Fly: After Hours Movers »

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SPWH

Sportsman's Warehouse

$3.46

-0.12 (-3.35%)

GLOB

Globant

$42.26

-0.64 (-1.49%)

ROST

Ross Stores

$53.33

-1.04 (-1.91%)

GPS

Gap

$22.68

0.11 (0.49%)

AMAT

Applied Materials

$43.12

-1.34 (-3.01%)

FLDM

Fluidigm

$3.60

-0.04 (-1.10%)

SENS

Senseonics

$2.44

0.02 (0.83%)

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LMT

Lockheed Martin

$301.42

-4.38 (-1.43%)

17:32
08/17/17
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17:32
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17:32
Hot Stocks
Lockheed Martin, others awarded $499M government contract »

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  • 23

    Aug

CTRL

Control4

$22.27

-0.9 (-3.88%)

, AMRI

Albany Molecular

$21.74

-0.01 (-0.05%)

17:21
08/17/17
08/17
17:21
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17:21
Hot Stocks
Control4 to replace Albany Molecular in S&P 600 at open on 8/22 »

The Carlyle Group (CG)…

CTRL

Control4

$22.27

-0.9 (-3.88%)

AMRI

Albany Molecular

$21.74

-0.01 (-0.05%)

CG

Carlyle Group

$21.20

-0.2 (-0.93%)

03/08/13
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  • 30

    Aug

CI

Cigna

$178.03

-1.83 (-1.02%)

17:15
08/17/17
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Cigna's Bacus sells 2,236 common shares »

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  • 06

    Sep

17:09
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17:09
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General news
Sen. Corker: Trump has not demonstrated competence to be president »

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BTU

Peabody Energy

$27.94

-0.27 (-0.96%)

17:07
08/17/17
08/17
17:07
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17:07
Syndicate
Peabody Energy files to sell 12.8M shares of common stock for holders »

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CEMI

Chembio Diagnostics

$6.05

-0.1 (-1.63%)

17:02
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Hot Stocks
Chembio Diagnostics CFO Richard Larkin to retire »

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CRMT

America's Car-Mart

$36.90

-0.65 (-1.73%)

17:01
08/17/17
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Earnings
America's Car-Mart reports Q1 EPS 90c, consensus 91c »

Reports Q1 revenue $146M,…

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GM

General Motors

$35.00

-0.75 (-2.10%)

16:59
08/17/17
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Hot Stocks
General Motors' Jacoby sells 20,000 common shares »

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CBI

CB&I

$9.78

-0.19 (-1.91%)

, FLR

Fluor

$37.77

-0.67 (-1.74%)

16:59
08/17/17
08/17
16:59
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16:59
Hot Stocks
President Donald Trump shelves plans to create infrastructure advisory council »

According to various…

CBI

CB&I

$9.78

-0.19 (-1.91%)

FLR

Fluor

$37.77

-0.67 (-1.74%)

ACM

Aecom

$31.09

-0.43 (-1.36%)

MTZ

MasTec

$39.20

0.45 (1.16%)

CCI

Crown Castle

$104.14

0.35 (0.34%)

JEC

Jacobs Engineering

$50.25

-0.8 (-1.57%)

MLM

Martin Marietta

$200.41

-4.7 (-2.29%)

USCR

U.S. Concrete

$77.20

-0.9 (-1.15%)

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  • 11

    Sep

CQP

Cheniere Energy Partners

$28.08

-0.08 (-0.28%)

16:53
08/17/17
08/17
16:53
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16:53
Syndicate
Breaking Syndicate news story on Cheniere Energy Partners »

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DDS

Dillard's

$54.83

-1.1 (-1.97%)

16:50
08/17/17
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Hot Stocks
Dillard's raises quarterly dividend to 10c from 7c per share »

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ABTL

Autobytel

$8.30

-0.12 (-1.43%)

16:46
08/17/17
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Hot Stocks
Autobytel announces purchases under stock repurchase authorization »

Autobytel announced that…

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GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

, CMT

Core Molding

$21.07

-0.36 (-1.68%)

16:43
08/17/17
08/17
16:43
08/17/17
16:43
Hot Stocks
Breaking Hot Stocks news story on GAMCO Investors, Core Molding »

Gabelli reports 10.94%…

GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

CMT

Core Molding

$21.07

-0.36 (-1.68%)

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  • 06

    Sep

GUID

Guidance Software

16:41
08/17/17
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16:41
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Breaking Hot Stocks news story on Guidance Software »

Soros Fund Management…

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GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

, MTRN

Materion

$37.00

-1.1 (-2.89%)

16:41
08/17/17
08/17
16:41
08/17/17
16:41
Hot Stocks
Breaking Hot Stocks news story on GAMCO Investors, Materion »

Gabelli reports 6.66%…

GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

MTRN

Materion

$37.00

-1.1 (-2.89%)

03/08/13
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    Nov

FALC

FalconStor

$0.19

-0.004 (-2.12%)

16:41
08/17/17
08/17
16:41
08/17/17
16:41
Hot Stocks
FalconStor announces Todd Brooks as CEO and Patrick McClain as CFO »

FalconStor announced the…

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16:36
08/17/17
08/17
16:36
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16:36
General news
Fed Balance Sheet Level data reported »

Week of 8/16 Fed Balance…

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