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NK

NantKwest

$6.48

-0.11 (-1.67%)

11:04
07/31/17
07/31
11:04
07/31/17
11:04

NantKwest announces durable complete responses in Phase I aNK cell trial

NantKwest announced the final results of a phase I clinical trial of the company's aNK cell therapy platform in relapsed hematological malignancies. The data, published in the journal Oncotarget, demonstrated continuing evidence of safety and efficacy, with an overall response rate of 42% and no evidence of grade 3 or 4 adverse events from the infusions. Of note 2 out of the 12 patients in the safety study with relapsed Hodgkin's Lymphoma and Multiple Myeloma, demonstrated durable complete response with single agent aNK therapy, and remain free of disease to date, 10 years and 2 years respectively. Chairman and CEO Patrick Soon-Shiong said, "Consistent with previous studies, Dr. Keating's clinical trial results, reporting a 42% overall response rate, provide additional clinical validation of the unique potential to deliver long-term remissions with limited toxicity using the company's novel NK cell therapy. Our aNK cell therapy is currently in an ongoing Phase II clinical study in Merkel cell carcinoma and represent a critical, foundational component in the company's recently launched NANT Cancer Vaccine clinical trial program."

NK NantKwest
$6.48

-0.11 (-1.67%)

05/16/17
05/16/17
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Pfizer (PFE) downgraded to Sell from Neutral at Citi with analyst Andrew Baum saying his concern over Pfizer's "rising risk to high price" Medicare Part D covered oncology drugs, namely Xtandi, Ibrance and Xalkori, has intensified. He also believes "major transaction risk" for Pfizer remains high. 2. MercadoLibre (MELI) downgraded to Neutral from Overweight at JPMorgan with analyst Andre Baggio citing valuation with the stock up 131% year-over-year. 3. Eli Lilly (LLY) downgraded to Buy from Conviction Buy at Goldman Sachs with analyst Jami Rubin citing strong year-to-date performance. The analyst maintained a Buy rating and $92 price target citing favorable long-term fundamentals with significant margin expansion. 4. Valero (VLO) downgraded to Neutral from Buy at Goldman Sachs with analyst Neil Mehta citing a more balanced risk/reward following the stock's outperformance. 5. NantKwest (NK) downgraded to Sell from Neutral at Citi with analyst Joel Beatty saying the company has a history of "significantly missing" its clinical trial timelines, and this is unlikely to change over the near-term. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
05/16/17
SBSH
05/16/17
DOWNGRADE
Target $3
SBSH
Sell
Citi cuts NantKwest to Sell on 'lack of execution'
Citi analyst Joel Beatty last night downgraded NantKwest to Sell from Neutral and lowered his price target for the shares to $3 from $4. The company has a history of "significantly missing" its clinical trial timelines, and this is unlikely to change over the near-term, Beatty tells investors in a research note. The analyst sees more downside risk on NantKwest's "lack of execution."
05/15/17
SBSH
05/15/17
DOWNGRADE
Target $3
SBSH
Sell
NantKwest downgraded to Sell from Neutral at Citi
Target $3.
03/24/17
ADAM
03/24/17
NO CHANGE
Target $7
ADAM
Buy
NantKwest price target lowered to $7 from $18 at Canaccord
Canaccord analyst Arinda Lee lowered her price target on NantKwest to $7 from $18 citing the delay of multiple clinical trials that were expected to begin in 2016. The analyst also lowered the probability of success for the company's aNK drug candidate given increasing competition and expected delayed launch by 1-2 years. Lee maintained her Buy rating on NantKwest shares.

TODAY'S FREE FLY STORIES

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BABA

Alibaba

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ASYS

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Syndicate
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CPCAY

Cathay Pacific

$7.47

0.15 (2.05%)

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Upgrade
Cathay Pacific rating change at Goldman Sachs »

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RTN

Raytheon

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SPWH

Sportsman's Warehouse

$3.46

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Globant

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LMT

Lockheed Martin

$301.42

-4.38 (-1.43%)

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Hot Stocks
Lockheed Martin, others awarded $499M government contract »

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  • 23

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CTRL

Control4

$22.27

-0.9 (-3.88%)

, AMRI

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$21.74

-0.01 (-0.05%)

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Control4 to replace Albany Molecular in S&P 600 at open on 8/22 »

The Carlyle Group (CG)…

CTRL

Control4

$22.27

-0.9 (-3.88%)

AMRI

Albany Molecular

$21.74

-0.01 (-0.05%)

CG

Carlyle Group

$21.20

-0.2 (-0.93%)

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CI

Cigna

$178.03

-1.83 (-1.02%)

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Cigna's Bacus sells 2,236 common shares »

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General news
Sen. Corker: Trump has not demonstrated competence to be president »

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BTU

Peabody Energy

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-0.27 (-0.96%)

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Syndicate
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CEMI

Chembio Diagnostics

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CRMT

America's Car-Mart

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Earnings
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GM

General Motors

$35.00

-0.75 (-2.10%)

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CBI

CB&I

$9.78

-0.19 (-1.91%)

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U.S. Concrete

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CQP

Cheniere Energy Partners

$28.08

-0.08 (-0.28%)

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DDS

Dillard's

$54.83

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ABTL

Autobytel

$8.30

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GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

, CMT

Core Molding

$21.07

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GBL

GAMCO Investors

$29.41

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Core Molding

$21.07

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GUID

Guidance Software

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GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

, MTRN

Materion

$37.00

-1.1 (-2.89%)

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Breaking Hot Stocks news story on GAMCO Investors, Materion »

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GAMCO Investors

$29.41

-0.4 (-1.34%)

MTRN

Materion

$37.00

-1.1 (-2.89%)

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FALC

FalconStor

$0.19

-0.004 (-2.12%)

16:41
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