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INO

Inovio

$5.43

-0.21 (-3.72%)

17:09
08/08/17
08/08
17:09
08/08/17
17:09

Inovio reports Q2 EPS (13c), consensus (19c)

Reports Q2 revenue $20.4M, consensus $16.29M.In June, Inovio commenced its phase 3 clinical program to evaluate the efficacy of Inovio's DNA-based immunotherapy, VGX-3100, to treat cervical dysplasia caused by human papillomavirus (HPV). Initiating Inovio's first phase 3 program marks a significant milestone for the company, for the next generation of DNA-based immunotherapies, and for women's health. In the phase 3 trial, Inovio will assess the efficacy of VGX-3100 in regressing cervical HSIL (high-grade squamous intraepithelial lesions; also called CIN2 or CIN3), a direct precursor to cervical cancer, and in eliminating the HPV infection that causes these lesions. The pivotal data from this program, if positive, could support the licensure of VGX-3100 as the first immunotherapy for this disease. HPV is the most common sexually transmitted infection, with over 14 million new infections annually. Inovio satisfied the FDA's request for information relating to its CELLECTRA(R) 5PSP delivery device, resulting in the FDA removing a previously imposed clinical hold on this program. During the hold period, Inovio prepared investigational sites for the phase 3 study, resulting in the company opening 27 sites in just over the first month since the hold was removed. Inovio is on track to open at least 50 sites by the end of the year.

  • 28

    Aug

INO Inovio
$5.43

-0.21 (-3.72%)

03/16/17
03/16/17
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Biogen (BIIB) was downgraded to Equal Weight from Overweight at Morgan Stanley and Market Perform from Outperform at Leerink. 2. United Continental (UAL) downgraded to In Line from Outperform at Evercore ISI. 3. Tyson Foods (TSN) downgraded to Hold from Buy at Argus with analyst John Staszak citing the SEC probe of Tyson and other poultry producers, potential decelerating earnings in coming quarters, and a recent bird flu outbreak in two states. 4. Williams-Sonoma (WSM) downgraded to Market Perform from Outperform at William Blair with analyst Daniel Hofkin citing the company's fourth quarter results. 5. Inovio (INO) downgraded to Neutral from Overweight at Piper Jaffray with analyst Charles Duncan saying a "lack of focus and advancement for any one program" poses execution risk to the broader platform, and to shareholders. The analyst lowered his price target for the shares to $9 from $13 following the company's Q4 results. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
05/24/17
MAXM
05/24/17
NO CHANGE
Target $12
MAXM
Buy
Inovio price target raised to $12 from $10 at Maxim
06/08/17
PIPR
06/08/17
UPGRADE
PIPR
Overweight
Inovio upgraded to Overweight from Neutral at Piper Jaffray
06/08/17
PIPR
06/08/17
UPGRADE
Target $14
PIPR
Overweight
Piper upgrades Inovio to Overweight after lifting of clinical hold
Piper Jaffray analyst Charles Duncan upgraded Inovio Pharmaceuticals to Overweight from Neutral and raised his price target for the shares to $14 from $9. The lifting of the clinical hold and Phase III trial start of VGX-3100 reduces risk, Duncan tells investors in a research note. The analyst now has confidence that Inovio's early-stage efforts can eventually move into later-stage.

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CVM

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LMT

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