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ANTH

Anthera

16:02
08/09/17
08/09
16:02
08/09/17
16:02

Anthera announces FDA orphan drug designation for blisibimod

Anthera Pharmaceuticals announced that blisibimod has received orphan drug designation from the U.S. Food and Drug Administration for the treatment of Immunoglobulin A nephropathy. Blisibimod targets B-cell activating factor, or BAFF, which has been shown to be elevated in a variety of B-cell mediated autoimmune diseases, including IgAN, systemic lupus erythematosus, and others. "We are pleased by the FDA's decision to designate blisibimod with orphan drug designation," said Craig Thompson, Chief Executive Officer of Anthera. "There remains a very high need for patients with IgA nephropathy, as no approved therapies currently exist despite the high proportion of patients who progress to end-stage renal disease. We remain optimistic that blisibimod may be a well-tolerated, disease-modifying therapeutic that targets the underlying pathology for IgAN." Anthera is currently analyzing the data from the randomized, double-blind, placebo controlled, Phase 2 BRIGHT-SC study of blisibimod in patients with IgA nephropathy (IgAN). After Week 24, patients were given the opportunity to continue blinded treatment for up to 104 weeks, discontinue treatment but continue to be followed, or discontinue from the study. Most patients, 42 of 57, completed at least 60 weeks of evaluation and 21 completed assessments through at least 104 weeks. Anthera anticipates reporting top-line data later this month.

ANTH Anthera

05/01/17
PIPR
05/01/17
NO CHANGE
Target $4
PIPR
Overweight
Piper adjusts Anthera target to $4 to account for stock-split, revised timelines
Piper Jaffray analyst Edward Tenthoff expects data from two phase 3 trials of Sollpura will enable Anthera Pharmaceuticals to make a BLA filing for the drug next year. He adjusted his price target on the stock to $4 to account for the company's 1-for-8 reverse stock split, its dilutive offering of stock and warrants and his revised view of the timelines for Sollpura. The analyst, who previously had a $12 price target on Anthera, keeps an Overweight rating on the shares.
03/14/17
PIPR
03/14/17
NO CHANGE
Target $1
PIPR
Overweight
Piper cuts Anthera target to $1 following capital raise
Piper Jaffray analyst Edward Tenthoff lowered his price target for Anthera Pharmaceuticals to $1.00 from $1.35 after the company issued 30M units at 50c. The deal is dilitive but enables the start of the Phase III RESULT trial, Tenthoff tells investors in a research note. The analyst maintains an Overweight rating on the shares.
12/29/16
12/29/16
NO CHANGE

On The Fly: Top five analyst actions
Catch up on today's top five analyst upgrades, downgrades, and initiations with this list compiled by The Fly: 1. Basic Energy (BAS) upgraded to Accumulate from Hold at Johnson Rice. 2. GameStop (GME) upgraded to Buy from Hold at Standpoint Research. 3. Anthera (ANTH) downgraded to Neutral from Buy at Citi and to Hold from Buy at Jefferies. 4. Senior Housing (SNH) initiated with an Overweight at Cantor. 5. Intrexon (XON) initiated with an Outperform at Northland with analyst Robert Breza saying valuation is compelling and its DNA analysis and engineering platform addresses a large market opportunity. The analyst views Deere's FY17 guidance as achievable. He kept an Outperform rating on the shares with a $117 price target. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
12/29/16
JEFF
12/29/16
DOWNGRADE
Target $1
JEFF
Hold
Anthera downgraded to Hold from Buy at Jefferies
Jefferies analyst Matthew Andrews downgraded Anthera Pharmaceuticals to Hold citing a lower probability of success for Sollpura following yesterday's failed Phase III study. The analyst cut his price target for the shares to $1 from $5. Citi this morning also downgraded Anthera.

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