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QURE

uniQure

$9.47

-2.2 (-18.85%)

07:07
10/19/17
10/19
07:07
10/19/17
07:07

uniQure acquires patent family providing protection of FIX-Padua

uniQure N.V. announced that the company has acquired a patent family, with claims issued in the U.S., that broadly covers a hyperactive variant of Factor IX carrying an R338L mutation and its use in gene therapy for the treatment of coagulopathies, including hemophilia B. This patent family was acquired from the inventor, Professor Paolo Simioni, a hemophilia expert at the University of Padua, Italy, who is widely recognized as the first to identify this mutant.Professor Simioni filed a PCT application on September 15, 2009, and patent applications are pending in the U.S., Europe, and Canada. The U.S. Patent and Trademark Office issued U.S. Patent 9,249,405 on February 2, 2016, which includes claims directed to Factor IX protein with a leucine at the R338 position of the protein sequence, nucleic acid sequences coding for this protein, and therapeutic applications, including gene therapy. Additional fast track divisional patent applications have also been filed in the U.S. and in Europe that would further strengthen uniQure's intellectual property position.

QURE uniQure
$9.47

-2.2 (-18.85%)

11/22/16
JEFF
11/22/16
DOWNGRADE
Target $8
JEFF
Hold
uniQure downgraded to Hold from Buy at Jefferies
Jefferies analyst Eun Yang downgraded uniQure to Hold citing execution risks and a lack of near-term catalysts. uniQure's strategic review and prioritization announced last week "comes up short" in providing confidence in the company's strategy and execution, Yang tells investors in a research note. She cut her price target for the shares to $8 from $28.
11/28/16
JANY
11/28/16
NO CHANGE
Target $12
JANY
Buy
uniQure price target lowered to $12 from $18 at Janney Capital
Janney Capital analyst Debjit Chattopadhyay acknowledged he has "been wrong on" uniQure so far and cut his fair value estimate on the stock to $12 from $18, adding that the upcoming Hemophilia B update at the ASH meeting "may not be [a] big enough catalyst for the stock." However, he keeps a Buy rating on uniQure shares, as he believes the bottom "could be probably close at hand" and the company's cash balance is sufficient to fund operations into 2019 while its major programs are still intact.
12/05/16
LEER
12/05/16
NO CHANGE
Target $9
LEER
Outperform
uniQure price target lowered to $9 from $23 at Leerink
Leerink analyst Joseph Schwartz assumed coverage of uniQure with an Outperform rating and lowered the price target on the shares to $9 from $23. The analyst believes the company's leadership and expertise in gene therapy should be a positive over the long-term, but resolutions to a number of uncertainties, questions, and optimizations remain essential in the near-term to enthuse investors.
06/29/17
OPCO
06/29/17
NO CHANGE
Target $17
OPCO
Outperform
Oppenheimer doctor survey supports bullish view on uniQure
Oppenheimer analyst Hartaj Singh says his firm's recent survey of 25 hematologists and oncologists supports his "continued bullish view" on uniQure. The survey suggests physician dissatisfaction with current treatments and a positive response to uniQure's blinded AMT-060 product profile, Singh tells investors in a research note. The analyst sees potential for 60% market penetration in three years after approval. He keeps an Outperform rating on uniQure with a $17 price target.

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