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FPRX

Five Prime

$21.84

-0.09 (-0.41%)

, BMY

Bristol-Myers

$61.89

0.14 (0.23%)

09:02
01/08/18
01/08
09:02
01/08/18
09:02

Five Prime earns IND milestone payment under collaboration with Bristol-Myers

Five Prime Therapeutics (FPRX) announced that it has achieved a milestone for the first Investigational New Drug application to the FDA by Bristol-Myers Squibb (BMY) for a therapeutic candidate under the immune checkpoint pathway discovery collaboration between the companies. The first clinical candidate from the collaboration is a fully-human monoclonal antibody targeting TIM-3, an immune checkpoint receptor that is known to limit the duration and magnitude of T-cell responses. This first IND application triggers a $5M milestone payment to Five Prime.

FPRX

Five Prime

$21.84

-0.09 (-0.41%)

BMY

Bristol-Myers

$61.89

0.14 (0.23%)

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FPRX Five Prime
$21.84

-0.09 (-0.41%)

11/07/17
SBSH
11/07/17
NO CHANGE
Target $65
SBSH
Buy
Citi says data puts safety of Five Prime's cabiralizumab in question
The key point of today's abstract was 43% G3-5 toxicity related to Five Prime Therapeutics' cabiralizumab, which puts the safety of the drug in question, Citi analyst Robyn Karnauskas tells investors in a research note. The analyst, who notes the data do show some durable activity, does not know at what dose the safety issues occurred. It remains unclear at this point if the activity being seen is due to checkpoint or cabiralizumab's contribution, Karnauskas writes. She models a 35% probability to the cabiralizumab program, which contributes $34 to her price target of $65. The analyst has a Buy rating on Five Prime. The stock is down 34% to $28.67.
11/07/17
JEFF
11/07/17
NO CHANGE
Target $52
JEFF
Buy
Five Prime data not as strong as expected, says Jefferies
Jefferies analyst Eun Yang says the 10% overall response rate with Five Prime Therapeutics' cabiralizumab plus Opdivo in second-line pancreatic cancer is lower than expected and the six-month disease control rate of 13%. The data are "not as strong as we like to see," but compares reasonably to chemo combo in second-line pancreatic cancer, Yang tells investors in a research note. The analyst has a Buy rating on Five Prime Therapeutics with a $52 price target. The stock in midday trading is down 34% to $28.69.
11/08/17
LEER
11/08/17
NO CHANGE
LEER
Outperform
Leerink sees Five Prime recovering some of yesterday's losses
After hosting an investor call to obtain additional information on the efficacy and safety profile of cabiralizumab in pancreatic cancer, Leerink analyst Michael Schmidt expects shares Five Prime Therapeutics (FPRX) will recover some of the losses from yesterday. The efficacy observed in yesterday's data look "quite promising," while safety looks very similar to what has been seen in Opdivo monotherapy trials historically, Schmidt tells investors in a research note. He notes that Five Prime partner Bristol-Myers (BMY) remains highly engaged in the cabiralizumab program. The analyst maintains an Outperform rating on Five Prime shares. The stock in midday trading is up 15%, or $3.85, to $29.71.
11/13/17
NOMU
11/13/17
NO CHANGE
Target $94
NOMU
Buy
Five Prime recent selloff looks unfounded, says Nomura Instinet
Nomura Instinet analyst Christopher Marai believes the cabira+nivo data has been taken out of context and that the recent selloff in shares of Five Prime Therapeutics looks unfounded. The data highlight "remarkable durable responses in patients not expected to respond," Marai tells investors in a research note. He points out that the IDO inhibitor epacadostat routinely only results in 10% benefit in overall response rate. Marai keeps a Buy rating on Five Prime with a $94 price target.
BMY Bristol-Myers
$61.89

0.14 (0.23%)

11/13/17
BMOC
11/13/17
NO CHANGE
BMOC
BMO says Pfizer buying Biogen makes more sense than deal for Bristol-Myers
BMO Capital analyst Alex Arfaei noted the "significant market speculation" that Pfizer (PFE) is preparing to execute a large M&A deal. While many sources, including Bloomberg, have speculated that Pfizer could target Bristol-Myers (BMY), Arfaei argues that a deal for Biogen (BIIB) would make more sense. He believes Pfizer has a significant gap in neurology, particularly in Alzheimer's, where it cannot afford to remain on the sidelines as its peers - including Biogen, Merck (MRK), AstraZeneca (AZN), and Eli Lilly (LLY) - all have pivotal trials in that area reading out in 2019-2020. Pfizer could have an opportunity to leverage near-term volatility in Biogen's MS franchise to strike a deal during the next 6-9 months before a potential interim look on aducanumab, which Arfaei views as the strongest of the next wave of Alzheimer's drugs in development, he tells investors.
11/30/17
GABE
11/30/17
NO CHANGE
Target $133
GABE
Buy
Incyte a top biotech pick for 2018 at Gabelli
Gabelli analyst Jing He highlighted Incyte as his top biotech pick for 2018 telling investors shares are undervalued and should benefit from the Epa melanoma data readout in first half 2018. The analyst said shares are trading near a 52-week low despite progress in the pipeline and believes competitors Bristol-Myers (BMY) and NewLink's (NLNK) IDO inhibitors are a few years behind Epa in development. Further, as tax reform gains more clarity, He believes M&A oncology deals could pickup and views Incyte as an attractive takeover target. Jing He rates Incyte a Buy with a $133 price target.
12/05/17
SBSH
12/05/17
NO CHANGE
Target $72
SBSH
Buy
Senate tax bill raises odds of Pfizer buying Bristol-Myers, says Citi
The Senate tax bill, which lowers the cost of bringing cash back home from outside the U.S., increases the probability of the "often-discussed" potential acquisition of Bristol-Myers Squibb (BMY) by Pfizer, Citi analyst Andrew Baum tells investors in a research note. The analyst points out that Pfizer has repeatedly underscored the importance of tax reform both from a competitive angle as well as from a merger perspective. Further, the analyst says that while Roche's (RHHBY) IMpower 150 Tecentriq lung cancer data in Geneva will take center stage this week, Bristol-Myers should benefit from two recent positive developments. The FDA's and Centers for Medicare and Medicaid Services' recommendation of Tumor Mutational Burden testing for lung cancer and other tumors will likely materially accelerate adoption and create more favorable reimbursement, Baum writes in a research note partially titled "Stars Converging for BMY." The analyst keeps a Buy rating on Bristol shares with a $72 price target. The stock closed yesterday down 76c to $62.47.

TODAY'S FREE FLY STORIES

FCX

Freeport McMoRan

$19.96

0.56 (2.89%)

21:10
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21:10
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Freeport McMoRan rating change at CIBC »

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DCM

NTT DoCoMo

$24.74

0.08 (0.32%)

21:09
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21:09
Downgrade
NTT DoCoMo rating change at HSBC »

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HAL

Halliburton

$53.01

0.65 (1.24%)

, PETS

PetMed Express

$53.24

2.67 (5.28%)

20:25
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01/21
20:25
01/21/18
20:25
Earnings
Notable companies reporting before Monday's open »

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HAL

Halliburton

$53.01

0.65 (1.24%)

PETS

PetMed Express

$53.24

2.67 (5.28%)

OPB

Opus Bank

$28.70

0.05 (0.17%)

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FB

Facebook

$181.29

1.49 (0.83%)

, NYT

New York Times

$21.90

1.7 (8.42%)

20:00
01/21/18
01/21
20:00
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20:00
Hot Stocks
On The Fly: Top five weekend stock stories »

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FB

Facebook

$181.29

1.49 (0.83%)

NYT

New York Times

$21.90

1.7 (8.42%)

NWSA

News Corp.

$17.22

0.21 (1.23%)

FOXA

21st Century Fox

$36.65

0.47 (1.30%)

AMZN

Amazon.com

$1,294.58

1.26 (0.10%)

AAPL

Apple

$178.46

-0.8 (-0.45%)

NFLX

Netflix

$220.46

0.13 (0.06%)

SNE

Sony

$49.89

0.72 (1.46%)

BA

Boeing

$337.73

-2.43 (-0.71%)

WMT

Walmart

$104.59

0.29 (0.28%)

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XRX

Xerox

$31.80

0.43 (1.37%)

19:18
01/21/18
01/21
19:18
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19:18
Periodicals
Icahn, Deason pushing for Xerox to explored sale, WSJ reports »

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FB

Facebook

$181.29

1.49 (0.83%)

18:22
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01/21
18:22
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18:22
Periodicals
Facebook to open three new digital training hubs in Europe, Reuters says »

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TWX

Time Warner

$93.36

0.39 (0.42%)

, CMCSA

Comcast

$42.50

0.65 (1.55%)

17:56
01/21/18
01/21
17:56
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17:56
Hot Stocks
Box Office Battle: 'Jumanji' wins weekend with $20M »

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TWX

Time Warner

$93.36

0.39 (0.42%)

CMCSA

Comcast

$42.50

0.65 (1.55%)

CMCSK

Comcast

SNE

Sony

$49.89

0.72 (1.46%)

FOX

21st Century Fox

$36.26

0.53 (1.48%)

FOXA

21st Century Fox

$36.65

0.47 (1.30%)

LGF.A

Lionsgate

$35.42

0.92 (2.67%)

DIS

Disney

$110.59

0.17 (0.15%)

VIAB

Viacom

$33.36

-0.59 (-1.74%)

VIA

Viacom

$39.20

-0.5 (-1.26%)

03/08/13
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03/06/13
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    Feb

CTIC

CTI BioPharma

16:11
01/21/18
01/21
16:11
01/21/18
16:11
Conference/Events
CTI BioPharma to host special shareholder meeting »

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ZSAN

Zosano Pharma

$0.45

-0.0387 (-7.92%)

16:00
01/21/18
01/21
16:00
01/21/18
16:00
Conference/Events
Zosano Pharma to host special shareholder meeting »

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SANM

Sanmina

$35.45

0.5 (1.43%)

15:39
01/21/18
01/21
15:39
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15:39
Conference/Events
Sanmina to hold a conference call »

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AMZN

Amazon.com

$1,294.58

1.26 (0.10%)

12:05
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12:05
Periodicals
Amazon automated grocery store opens Monday, Reuters says »

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TWTR

Twitter

$23.66

-0.38 (-1.58%)

09:07
01/21/18
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09:07
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09:07
Periodicals
Twitter COO in discussions to become SoFi CEO, WSJ reports »

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CLF

Cleveland-Cliffs

$8.49

0.08 (0.95%)

09:02
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BMY

Bristol-Myers

$62.28

0.45 (0.73%)

15:26
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Opdivo, Yervoy combo demonstrates activity in patients with dMMR, MSI-H mCRC »

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EXEL

Exelixis

$28.00

0.14 (0.50%)

, RHHBY

Roche

$30.69

0.18 (0.59%)

15:22
01/20/18
01/20
15:22
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15:22
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Exelixis presents updated results from Phase 1b clinical trial in CRC »

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EXEL

Exelixis

$28.00

0.14 (0.50%)

RHHBY

Roche

$30.69

0.18 (0.59%)

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ARRY

Array BioPharma

$13.14

0.26 (2.02%)

15:17
01/20/18
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15:17
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15:17
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Array BioPharma updates results from BEACON Phase 3 trial »

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SO

Southern Company

$44.44

-0.46 (-1.02%)

15:13
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15:13
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Southern Company accelerates restoration efforts in Puerto Rico »

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TECK

Teck Resources

$29.43

0.19 (0.65%)

15:10
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Teck Resources announces Elkview incident »

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  • 14

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TWTR

Twitter

$23.66

-0.38 (-1.58%)

14:03
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Twitter begins notifying users exposed to Russian propaganda during elections »

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  • 23

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SPY

SPDR S&P 500 ETF Trust

$280.41

1.27 (0.45%)

, SPX

S&P 500

13:58
01/20/18
01/20
13:58
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Government shuts down on anniversary of Trump presidency, Reuters reports »

President's Trump…

SPY

SPDR S&P 500 ETF Trust

$280.41

1.27 (0.45%)

SPX

S&P 500

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FB

Facebook

$181.29

1.49 (0.83%)

, NYT

New York Times

$21.90

1.7 (8.42%)

13:48
01/20/18
01/20
13:48
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13:48
Periodicals
NY Times stock jumps after Facebook's announcement, Recode reports »

Facebook (FB) CEO Mark…

FB

Facebook

$181.29

1.49 (0.83%)

NYT

New York Times

$21.90

1.7 (8.42%)

NWSA

News Corp.

$17.22

0.21 (1.23%)

FOXA

21st Century Fox

$36.65

0.47 (1.30%)

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WMT

Walmart

$104.59

0.29 (0.28%)

13:36
01/20/18
01/20
13:36
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13:36
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Still time to shop Walmart shares as company makes changes, Barron's says »

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  • 20

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AAPL

Apple

$178.46

-0.8 (-0.45%)

, NFLX

Netflix

$220.46

0.13 (0.06%)

08:59
01/20/18
01/20
08:59
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08:59
Periodicals
Netflix among likely candidates for an Apple purchase, Barron's says »

Especially for tech…

AAPL

Apple

$178.46

-0.8 (-0.45%)

NFLX

Netflix

$220.46

0.13 (0.06%)

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BA

Boeing

$337.73

-2.43 (-0.71%)

08:50
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Boeing not a sell just yet, Barron's says »

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AAPL

Apple

$178.46

-0.8 (-0.45%)

, EADSY

Airbus

$28.43

0.755 (2.73%)

08:24
01/20/18
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Hot Stocks
Week in review: How Trump's policies moved stocks »

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AAPL

Apple

$178.46

-0.8 (-0.45%)

EADSY

Airbus

$28.43

0.755 (2.73%)

BA

Boeing

$337.73

-2.43 (-0.71%)

VZ

Verizon

$51.91

0.36 (0.70%)

NYT

New York Times

$21.90

1.7 (8.42%)

TWX

Time Warner

$93.36

0.39 (0.42%)

DIS

Disney

$110.59

0.17 (0.15%)

TIME

Time Inc.

$18.55

0.05 (0.27%)

AMZN

Amazon.com

$1,294.58

1.26 (0.10%)

BAC

Bank of America

$31.72

0.24 (0.76%)

GS

Goldman Sachs

$256.12

5.15 (2.05%)

BK

BNY Mellon

$56.61

1.26 (2.28%)

WLKP

Westlake Chemical Partners

$24.45

-0.1 (-0.41%)

MON

Monsanto

$120.66

1.8 (1.51%)

DLTR

Dollar Tree

$114.73

1.83 (1.62%)

CE

Celanese

$112.96

1.93 (1.74%)

LYB

LyondellBasell

$119.92

3.03 (2.59%)

TSE

Trinseo

$79.45

2.2 (2.85%)

EYE

National Vision

$43.13

1.12 (2.67%)

ETFC

E-Trade

$54.28

0.63 (1.17%)

LPLA

LPL Financial

$59.03

0.53 (0.91%)

AMTD

TD Ameritrade

$55.17

0.21 (0.38%)

SCHW

Charles Schwab

$55.48

0.15 (0.27%)

ADS

Alliance Data

$261.82

5.88 (2.30%)

FISV

Fiserv

$138.11

0.17 (0.12%)

FLT

FleetCor

$206.65

3.4 (1.67%)

HAWK

Blackhawk

$45.25

0.1 (0.22%)

MTZ

MasTec

$53.30

1.25 (2.40%)

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