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CYAD

Celyad

17:07
03/22/18
03/22
17:07
03/22/18
17:07

Celyad reports operating results, expected key milestones for 2018

The company provided an update on its recent operations and reported consolidated financial results for the twelve-month period ended 31 December 2017, prepared in accordance with IFRS.Christian Homsy, CEO of Celyad: "2017 has been another milestone year for Celyad. The responses obtained to date in AML, and in solid tumors, we believe validate NKG2D as a target and allow us to move rapidly forward with the development of this product candidate in 2018. Our intellectual property related to the allogeneic technology, another of our core strengths, has been further strengthened: it was upheld by the US Patent and Trademark Office as part of multiple ex-parte re-examination requests and its importance has been recognized through our licensing agreement with Novartis. As far as 2018 is concerned: we believe it will be an exciting year as we expect to - among other things- complete the dose escalation segment of THINK and explore the various conditions that could lead to a potential registrational Phase 2 trial." Celyad reported steady progress in 2017 with the advancement of the clinical development of CYAD-01. Data collected thus far from the THINK trial, which started in early 2017, show that CYAD-01 has been well-tolerated, offers an excellent safety profile and validates the activity of the NKG2D receptor.In terms of financing, Celyad reported EURO$34Mn at year end 2017. This, together with anticipated milestone payments expected to be received by Celyad in 2018 from its strategic partners, should enable the company to finance all its clinical programs and other needs through the first half of 2019.

CYAD Celyad

10/09/17
PIPR
10/09/17
NO CHANGE
Target $74
PIPR
Overweight
Celyad price target raised to $74 from $49 at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff raised his price target for Celyad to $74 after the company last week reported the first ever Morphologic Leukemia-Free Status in an Acute Myeloid Leukemia patient in the first dose cohort of the Phase Ib Think study of CYAD-01 without preconditioning. Fourteen solid and hematologic tumor patients have been dosed in Think and escalation continues with no deaths, Tenthoff tells investors in an intraday research note. He added $258M in value for CYAD-01 in colorectal cancer based on the two patients with stable disease in Think and Celyad's plans to expand enrollment and initiate the Shrink and Link studies. The analyst, who points out his firm has been retained by Celyad as its financial advisor to explore strategic alternatives, reiterates an Overweight rating on the shares.

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