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IMGN

ImmunoGen

$12.10

-0.06 (-0.49%)

, MRK

Merck

$53.41

-0.71 (-1.31%)

08:14
03/25/18
03/25
08:14
03/25/18
08:14

ImmunoGen presents data from FORWARD II assessment of Mirvetuximab Soravtansine

ImmunoGen (IMGN) announced encouraging efficacy and favorable tolerability data from the FORWARD II cohort assessing mirvetuximab soravtansine in combination with Merck's (MRK) anti-PD-1 therapy pembrolizumab in patients with platinum-resistant epithelial ovarian cancer. In the subset of 8 patients with medium or high folate receptor alpha expression levels, the confirmed overall response rate was 63%, with a median progression-free survival of 8.6 months. For all patients, the confirmed ORR was 43%, with a median PFS of 5.2 months; patients in this cohort had received a median of 4.5 prior lines of systemic therapy, with 64% of patients receiving 4 or more prior lines. As previously reported, at full dosing, the combination of mirvetuximab and pembrolizumab demonstrates favorable tolerability, consistent with the known safety profiles of each agent, with primarily mild to moderate adverse events observed. Based on these data, ImmunoGen is enrolling an additional 35 patients with medium or high FRalpha expression levels in an expansion cohort in the FORWARD II study.

IMGN

ImmunoGen

$12.10

-0.06 (-0.49%)

MRK

Merck

$53.41

-0.71 (-1.31%)

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    Oct

IMGN ImmunoGen
$12.10

-0.06 (-0.49%)

01/31/18
HCWC
01/31/18
INITIATION
Target $18
HCWC
Buy
ImmunoGen initiated with a Buy at H.C. Wainwright
H.C. Wainwright analyst Debjit Chattopadhyay started ImmunoGen with a Buy rating and $18 price target. The analyst believes ADC's, a multi-component system involving a targeting antibody linked to cytotoxic agents, have a "significant and hitherto underappreciated role to play in the war against cancer." He believes ImmunoGen has a differentiated ADC platform.
01/31/18
01/31/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Lumentum (LITE) was initiated with a Buy at UBS while Oclaro (OCLR) was initiated with a Sell. 2. ImmunoGen (IMGN) initiated with a Buy at H.C. Wainwright. 3. Salesforce (CRM) and Workday (WDAY) were initiated with a Buy at Cleveland Research. 4. Cooper Tire (CTB) was initiated with a Buy at Longbow, while Goodyear Tire (GT) was initiated with a Neutral. 5. Acacia Communications (ACIA) initiated with a Buy at UBS. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
02/08/18
RBCM
02/08/18
INITIATION
Target $12
RBCM
Outperform
ImmunoGen assumed with an Outperform at RBC Capital
RBC Capital analyst Kennen MacKay assumed coverage of ImmunoGen with an Outperform rating and a price target of $9. MacKay notes "mirvetuximab's market opportunity in 2L+ platinum-resistant/refractory folate receptor alpha positive ovarian cancer", modeling potential $850M in peak risk-unadjusted sales. MacKay also points to the positive impact of U.S. tax changes and believes 2018 could be a "transformational year" with a scheduled futility analysis planned ahead of top-line data in the first half of 2019.
03/21/18
RBCM
03/21/18
NO CHANGE
Target $16
RBCM
Outperform
ImmunoGen price target raised to $16 from $12 at RBC Capital
RBC Capital analyst Kennen MacKay raised his price target on ImmunoGen to $16 and kept his Outperform rating. MacKay cites the Mirvetuximab combo opportunities as a potential catalyst ahead of the SGO data which he contends may provide initial indications of the combo's synergistic activity.
MRK Merck
$53.41

-0.71 (-1.31%)

03/02/18
LEER
03/02/18
NO CHANGE
Target $29
LEER
Outperform
Leerink ups Heron Therapeutics target to $29 after competitor setback
Leerink analyst Ami Fadia raised her price target for Heron Therapeutics (HRTX) to $29 from $27 after Tesaro (TSRO) announced earlier this week that it has withdrawn all promotional support for IV Varubi, based on numerous reports of anaphylaxis. Heron's Cinvanti, Tesaro's Varubi and Merck's (MRK) Emend are the only three branded NK-1 antagonists in the market today for chemo induced nausea and vomiting, Fadia tells investors in a research note. With Emend expected to go generic soon, Cinvanti will be the sole marketed branded agent, the analyst adds. She increased her 2023 estimate for Cinvanti from $150M to just under $200M and keeps an Outperform rating on Heron Therapeutics. The analyst continues to see upside for the stock ahead of the two Phase 3 trials for HTX-011 expected to read out in Q2.
03/12/18
LEER
03/12/18
UPGRADE
LEER
Outperform
Merck upgraded to Outperform from Market Perform at Leerink
03/12/18
LEER
03/12/18
UPGRADE
Target $66
LEER
Outperform
Leerink upgrades Merck to Outperform ahead of KN-189 presentation
Leerink analyst Seamus Fernandez upgraded Merck (MRK) to Outperform from Market Perform with an unchanged price target of $66. The shares closed Friday up 38c to $55.14. Keytruda will continue to dominate the first-line non-small cell lung cancer market, Fernandez tells investors in a research note. Following his firm's lung cancer survey, the analyst believes Merck will deliver upside to consensus Keytruda estimates along with positive earnings leverage in the second half of 2018 and 2019. He thinks KN-189 likely will show a clinically meaningful overall survival benefit for the Keytruda plus chemo combo in all patients, including a strong benefit in patients with moderate or low PD-L1 biomarker levels. Fernandez does not believe Bristol-Myers' (BMY) Opdivo and Yervoy combo will supplant Keytruda as the market leader. The analyst thinks now is the time to own shares of Merck.
03/12/18
03/12/18
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Time Warner (TWX) upgraded to Buy from Neutral at UBS with analyst John Hodulik saying while he expects the takeover by AT&T (T) to receive regulatory approval, he believes the current environment would make Time Warner's assets "highly attractive" to other media companies and Internet-based competitors were the deal to be blocked. 2. Carlyle Group (CG) and Apollo Global (APO) were upgraded to Buy from Neutral at Citi. 3. Merck (MRK) upgraded to Outperform from Market Perform at Leerink with analyst Seamus Fernandez saying Keytruda will continue to dominate the first-line non-small cell lung cancer market. 4. SAP (SAP) upgraded to Outperform from In Line at Evercore ISI with analyst Stewart Materne III saying that he believes the risk/reward is more attractive at current levels following the stock's 6% pullback. 5. Aratana Therapeutics (PETX) upgraded to Buy on valuation at CL King with the firm citing favorable risk/reward. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

AKRX

Akorn

$19.68

0.31 (1.60%)

, FSNUY

Fresenius SE

14:08
04/22/18
04/22
14:08
04/22/18
14:08
Hot Stocks
Fresenius terminates merger agreement with Akorn over data breaches »

Fresenius (FSNUY) decided…

AKRX

Akorn

$19.68

0.31 (1.60%)

FSNUY

Fresenius SE

03/08/13
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LEVB

Level Brands

$5.15

0.25 (5.10%)

12:20
04/22/18
04/22
12:20
04/22/18
12:20
Conference/Events
Level Brands CEO Sumichrast interview to air on The RedChip Money Report »

Marty Sumichrast,…

03/08/13
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LEVB

Level Brands

$5.15

0.25 (5.10%)

04:55
04/22/18
04/22
04:55
04/22/18
04:55
Conference/Events
Level Brands CEO Sumichrast interview to air on The RedChip Money Report »

Marty Sumichrast,…

03/08/13
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04:55
04/22/18
04/22
04:55
04/22/18
04:55
Conference/Events
International Monetary Fund & World Bank Group to co-host an annual meeting »

2018 Spring Meeting will…

CGNT

Cogentix Medical

$3.84

-0.005 (-0.13%)

19:21
04/21/18
04/21
19:21
04/21/18
19:21
Hot Stocks
Laborie Medical announces completion of tender offer for Cogentix Medical »

Laborie Medical…

03/08/13
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TSG

The Stars Group

$29.35

0.4 (1.38%)

, SKYAY

Sky

18:31
04/21/18
04/21
18:31
04/21/18
18:31
Hot Stocks
The Stars Group to acquire Sky Betting & Gaming for $4.7B »

The Stars Group (TSG)…

TSG

The Stars Group

$29.35

0.4 (1.38%)

SKYAY

Sky

03/08/13
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LUV

Southwest

$54.76

-0.02 (-0.04%)

18:22
04/21/18
04/21
18:22
04/21/18
18:22
Hot Stocks
Southwest responds to Emergency Airworthiness Directive »

Southwest Airlines said…

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TPR

Tapestry

$53.03

-0.255 (-0.48%)

16:17
04/21/18
04/21
16:17
04/21/18
16:17
Periodicals
Tapestry could see more stock gains, Barron's says »

In a follow-up story,…

03/08/13
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03/08/13
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03/06/13
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03/06/13
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DAL

Delta Air Lines

$55.40

0.34 (0.62%)

, GM

General Motors

$37.61

-0.16 (-0.42%)

16:05
04/21/18
04/21
16:05
04/21/18
16:05
Periodicals
Delta, GM look cheap, with growth potential, Barron's says »

While a solid start to…

DAL

Delta Air Lines

$55.40

0.34 (0.62%)

GM

General Motors

$37.61

-0.16 (-0.42%)

GT

Goodyear Tire

$27.00

0.06 (0.22%)

LNC

Lincoln National

$71.59

-0.04 (-0.06%)

03/08/13
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03/06/13
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GIS

General Mills

$43.41

-0.61 (-1.39%)

15:57
04/21/18
04/21
15:57
04/21/18
15:57
Periodicals
General Mills shares fall to 'bargain territory,' Barron's says »

General Mills has fallen…

03/08/13
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CCL

Carnival

$65.88

0.82 (1.26%)

, RCL

Royal Caribbean

$119.11

1.18 (1.00%)

15:51
04/21/18
04/21
15:51
04/21/18
15:51
Periodicals
Cruise operators can offer 'nice' yields, solid dividend growth, Barron's says »

Cruise operators, like…

CCL

Carnival

$65.88

0.82 (1.26%)

RCL

Royal Caribbean

$119.11

1.18 (1.00%)

NCLH

Norwegian Cruise Line

$55.65

0.71 (1.29%)

DIS

Disney

$100.24

-0.64 (-0.63%)

03/08/13
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03/08/13
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03/06/13
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03/06/13
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GOOG

Alphabet

$1,072.73

-15.18 (-1.40%)

, GOOGL

Alphabet Class A

$1,076.64

-12.83 (-1.18%)

15:42
04/21/18
04/21
15:42
04/21/18
15:42
Periodicals
Tech giants may make own custom chips to get edge on one another, Barron's says »

There has been a tension…

GOOG

Alphabet

$1,072.73

-15.18 (-1.40%)

GOOGL

Alphabet Class A

$1,076.64

-12.83 (-1.18%)

AMZN

Amazon.com

$1,527.39

-29.57 (-1.90%)

FB

Facebook

$166.29

-1.82 (-1.08%)

AAPL

Apple

$165.71

-7.08 (-4.10%)

MSFT

Microsoft

$95.01

-1.1 (-1.14%)

BIDU

Baidu

$232.38

-4.73 (-1.99%)

BABA

Alibaba

$179.07

-2.14 (-1.18%)

INTC

Intel

$51.53

-0.68 (-1.30%)

NVDA

Nvidia

$228.74

-0.21 (-0.09%)

03/08/13
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03/08/13
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03/06/13
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03/06/13
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EPD

Enterprise Products

$26.60

-0.03 (-0.11%)

, MMP

Magellan Midstream

$65.16

-0.755 (-1.15%)

15:32
04/21/18
04/21
15:32
04/21/18
15:32
Periodicals
MPL valuations look cheap, Barron's says »

Master limited…

EPD

Enterprise Products

$26.60

-0.03 (-0.11%)

MMP

Magellan Midstream

$65.16

-0.755 (-1.15%)

MPLX

MPLX

PAA

Plains All American

$24.68

0.42 (1.73%)

03/08/13
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03/08/13
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03/06/13
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03/06/13
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AMZN

Amazon.com

$1,527.39

-29.57 (-1.90%)

, TWX

Time Warner

$96.23

-0.34 (-0.35%)

08:34
04/21/18
04/21
08:34
04/21/18
08:34
Periodicals
Trump's tweets politicize U.S. markets, Barron's says »

With President Donald…

AMZN

Amazon.com

$1,527.39

-29.57 (-1.90%)

TWX

Time Warner

$96.23

-0.34 (-0.35%)

T

AT&T

$34.67

-0.15 (-0.43%)

MYL

Mylan

$40.73

-0.08 (-0.20%)

03/08/13
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03/08/13
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03/06/13
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FB

Facebook

$166.29

-1.82 (-1.08%)

, AAPL

Apple

$165.71

-7.08 (-4.10%)

08:15
04/21/18
04/21
08:15
04/21/18
08:15
Periodicals
Facebook, Apple embody new tech divide, Barron's says »

For several years now,…

FB

Facebook

$166.29

-1.82 (-1.08%)

AAPL

Apple

$165.71

-7.08 (-4.10%)

AMZN

Amazon.com

$1,527.39

-29.57 (-1.90%)

NFLX

Netflix

$327.57

-5.12 (-1.54%)

GOOG

Alphabet

$1,072.73

-15.18 (-1.40%)

GOOGL

Alphabet Class A

$1,076.64

-12.83 (-1.18%)

03/08/13
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AMZN

Amazon.com

$1,527.39

-29.57 (-1.90%)

, ACIA

Acacia Communications

$27.54

1.04 (3.92%)

08:00
04/21/18
04/21
08:00
04/21/18
08:00
Hot Stocks
Week in review: How Trump's policies moved stocks »

Catch up on the top…

AMZN

Amazon.com

$1,527.39

-29.57 (-1.90%)

ACIA

Acacia Communications

$27.54

1.04 (3.92%)

OCLR

Oclaro

$8.27

0.08 (0.98%)

NOK

Nokia

$5.96

0.125 (2.14%)

NPTN

NeoPhotonics

$6.05

-0.01 (-0.17%)

LITE

Lumentum

$58.90

-1.05 (-1.75%)

FNSR

Finisar

$15.43

0.045 (0.29%)

MSFT

Microsoft

$95.01

-1.1 (-1.14%)

03/08/13
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03/08/13
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03/06/13
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03/06/13
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  • 12

    Jun

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04:55
04/21/18
04/21
04:55
04/21/18
04:55
Conference/Events
International Monetary Fund & World Bank Group to co-host an annual meeting »

2018 Spring Meeting will…

SPX

S&P 500

, SPY

SPDR S&P 500 ETF Trust

$266.66

-2.18 (-0.81%)

18:08
04/20/18
04/20
18:08
04/20/18
18:08
Periodicals
North Korea to suspend nuclear and ICBM tests, Bloomberg reports »

North Korea also plans to…

SPX

S&P 500

SPY

SPDR S&P 500 ETF Trust

$266.66

-2.18 (-0.81%)

03/08/13
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03/08/13
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03/06/13
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ADM

Archer Daniels

$45.50

-0.295 (-0.64%)

, BG

Bunge

$73.72

-1.935 (-2.56%)

18:03
04/20/18
04/20
18:03
04/20/18
18:03
Periodicals
Archer Daniels, Bunge talks end without merger deal, Bloomberg reports »

Advanced merger…

ADM

Archer Daniels

$45.50

-0.295 (-0.64%)

BG

Bunge

$73.72

-1.935 (-2.56%)

03/08/13
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  • 02

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CE

Celanese

$111.69

0.56 (0.50%)

18:02
04/20/18
04/20
18:02
04/20/18
18:02
Hot Stocks
Celanese announces price increases in Asia »

Celanese will increase…

03/08/13
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03/06/13
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  • 01

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    May

IOTS

Adesto Technologies

$8.65

-0.2 (-2.26%)

17:33
04/20/18
04/20
17:33
04/20/18
17:33
Hot Stocks
Breaking Hot Stocks news story on Adesto Technologies »

180 Degree Capital lowers…

03/08/13
Wedge Partners
03/08/13
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03/06/13
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03/06/13
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  • 23

    May

SIGM

Sigma Designs

$6.30

0.1 (1.61%)

17:22
04/20/18
04/20
17:22
04/20/18
17:22
Hot Stocks
Sigma Designs to delay filing Annual Report on Form 10-K »

Sigma Designs is unable…

03/08/13
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03/08/13
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03/06/13
Citigroup
03/06/13
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BRK.A

Berkshire Hathaway

$300,140.00

-260 (-0.09%)

, BRK.B

Berkshire Hathaway

$200.09

-0.32 (-0.16%)

17:22
04/20/18
04/20
17:22
04/20/18
17:22
Hot Stocks
Breaking Hot Stocks news story on Berkshire Hathaway, Berkshire Hathaway, Torchmark »

Berkshire Hathaway…

BRK.A

Berkshire Hathaway

$300,140.00

-260 (-0.09%)

BRK.B

Berkshire Hathaway

$200.09

-0.32 (-0.16%)

TMK

Torchmark

$87.22

0.02 (0.02%)

03/08/13
Wedge Partners
03/08/13
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03/06/13
Citigroup
03/06/13
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SMHI

SEACOR Marine Holdings

$22.90

-0.86 (-3.62%)

, CG

Carlyle Group

$20.85

0.15 (0.72%)

17:17
04/20/18
04/20
17:17
04/20/18
17:17
Syndicate
SEACOR Marine Holdings announces $56.9M private placement of common stock »

SEACOR Marine Holdings…

SMHI

SEACOR Marine Holdings

$22.90

-0.86 (-3.62%)

CG

Carlyle Group

$20.85

0.15 (0.72%)

03/08/13
Wedge Partners
03/08/13
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03/06/13
Citigroup
03/06/13
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  • 12

    Jun

AVAV

AeroVironment

$56.66

-0.15 (-0.26%)

17:12
04/20/18
04/20
17:12
04/20/18
17:12
Hot Stocks
AeroVironment awarded $44.7M U.S. Army contract modification »

AeroVironment was awarded…

03/08/13
Wedge Partners
03/08/13
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03/06/13
Citigroup
03/06/13
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  • 09

    May

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