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PFE

Pfizer

$36.45

0.21 (0.58%)

17:43
06/04/18
06/04
17:43
06/04/18
17:43

Pfizer announces OS improvement in dacomitinib compared to gefitinib at ASCO

Pfizer announced overall survival, or OS, data from the ARCHER 1050 trial evaluating dacomitinib as a first-line treatment for patients with locally advanced or metastatic non-small cell lung cancer, or NSCLC, with EGFR-activating mutations compared to gefitinib. The trial showed a median OS of 34.1 months for patients receiving dacomitinib, representing a more than seven-month improvement compared to 26.8 months with gefitinib. The OS data from ARCHER 1050 were presented as an oral presentation at the 54th Annual Meeting of the American Society of Clinical Oncology, or ASCO. Overall survival was a secondary endpoint of ARCHER 1050, a randomized, open label Phase 3 study comparing the efficacy and safety of dacomitinib to gefitinib for the first-line treatment of locally advanced or metastatic NSCLC in subjects with EGFR-activating mutations. At the OS data cutoff, median OS was 34.1 months with dacomitinib compared to 26.8 months with gefitinib. Patients receiving dacomitinib had a 56.2% survival rate at 30 months compared with 46.3% for patients who received gefitinib. Subgroup analyses were consistent with the primary OS analysis across most baseline characteristics, including patients with common sub-mutations exon 19 and 21. The adverse events, or AEs, observed with dacomitinib in the study were consistent with findings from previous dacomitinib trials. The most common AEs were diarrhea, nail changes, rash/dermatitis acneiform and mouth sores.

  • 05

    Jun

PFE Pfizer
$36.45

0.21 (0.58%)

04/19/18
04/19/18
NO CHANGE

BTIG says Allergan may be interested in Shire after insufficient Takeda offers
BTIG analyst Timothy Chiang noted that Shire (SHPG) is trading higher after news that at least one other company other than Takeda (TKPYY) is interested in acquiring Shire, and naming Allergan (AGN) as one of those possible suitors. Chiang also believes that other companies, such as Pfizer (PFE), could entering into the bidding for Shire. BTIG maintained a Buy rating and $195 price target on Shire shares.
05/15/18
LEER
05/15/18
NO CHANGE
Target $121
LEER
Outperform
Sarepta price target raised to $121 from $88 at Leerink
Leerink analyst Joseph Schwartz raised his price target for Sarepta (SRPT) to $121 from $88, while reiterating an Outperform rating on the shares. The analyst notes that Sarepta is one of three companies developing microdystrophin gene therapy for Duchenne muscular dystrophy, in competition with Pfizer (PFE) who acquired Bamboo, and Solid Biosciences (SLDB). With Solid's clinical hold still in place, Sarepta could potentially be first-to-market, and is expected to report the first clinical data for a micro-dystrophin candidate at their R&D day on June 19, he adds.
05/16/18
MSCO
05/16/18
NO CHANGE
Target $200
MSCO
Overweight
Epogen biosimilar should have little impact on Amgen, says Morgan Stanley
After the FDA approved Retacrit, Pfizer's (PFE) biosimilar version of Amgen's (AMGN) Epogen, Morgan Stanley analyst Matthew Harrison said he does not see significant impact to his forecasts due to the news, noting that Amgen has already discounted Epogen net selling price significantly to secure an extended supply agreement with DaVita (DVA). Amgen renegotiated the supply agreement in early 2017 and the vast majority of Epogen volume is from DaVita, added Harrison, who maintains an Overweight rating and $200 price target on Amgen shares.
06/01/18
PIPR
06/01/18
NO CHANGE
PIPR
Overweight
Piper says Lilly should get some share for Olumiant with aggressive pricing
Piper Jaffray analyst Tyler Van Buren noted that the TNF step-through for Incyte (INCY) and Eli Lilly's (LLY) Olumiant potentially decreases the overall market opportunity, but he believes Olumiant will get some share of TNF failure patients given that Lilly announced it is pricing the drug "aggressively" at a potential 60% price discount to AbbVie's (ABBV) Humira. Van Buren estimates this price to be a potential 50% price discount to the other oral JAK approved for RA, Pfizer's (PFE) Xeljanz. The analyst keeps an Overweight rating on Incyte, citing the durable revenue base through the late 2020s that should come from Olumiant along with the "significant potential" he sees in its pipeline opportunities.

TODAY'S FREE FLY STORIES

FCAU

Fiat Chrysler

$19.33

-0.195 (-1.00%)

13:14
07/21/18
07/21
13:14
07/21/18
13:14
Hot Stocks
Fiat names Jeep head as CEO as Marchionne's health worsens »

In a statement, Fiat…

03/08/13
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RACE

Ferrari

$139.98

-2.65 (-1.86%)

, PM

Philip Morris

$84.31

3.41 (4.22%)

13:10
07/21/18
07/21
13:10
07/21/18
13:10
Hot Stocks
Ferrari to name former Philip Morris chairman as CEO »

The Board of Directors of…

RACE

Ferrari

$139.98

-2.65 (-1.86%)

PM

Philip Morris

$84.31

3.41 (4.22%)

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  • 01

    Aug

AMZN

Amazon.com

$1,813.84

0.99 (0.05%)

, TM

Toyota

$131.87

0.11 (0.08%)

12:51
07/21/18
07/21
12:51
07/21/18
12:51
Periodicals
Amazon, others working to counter Trump's tariff plans, Reuters says »

Big companies in the…

AMZN

Amazon.com

$1,813.84

0.99 (0.05%)

TM

Toyota

$131.87

0.11 (0.08%)

AA

Alcoa

$40.32

-1.36 (-3.26%)

03/08/13
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  • 26

    Jul

  • 16

    Aug

FCAU

Fiat Chrysler

$19.33

-0.195 (-1.00%)

12:47
07/21/18
07/21
12:47
07/21/18
12:47
Periodicals
Fiat Chrysler's Sergio Marchionne to step down, NYTimes reports »

Fiat Chrysler's…

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FCAU

Fiat Chrysler

$19.33

-0.195 (-1.00%)

12:43
07/21/18
07/21
12:43
07/21/18
12:43
Periodicals
Fiat Chrysler to name Jeep's Manley as CEO, Reuters reports »

Fiat Chrysler has named…

03/08/13
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BABA

Alibaba

$187.21

-0.14 (-0.07%)

, TCEHY

Tencent

$0.00

(0.00%)

12:40
07/21/18
07/21
12:40
07/21/18
12:40
Periodicals
Alibaba, Tencent in talks to buy stake in WPP's Chinese unit, Reuters says »

Alibaba (BABA) and…

BABA

Alibaba

$187.21

-0.14 (-0.07%)

TCEHY

Tencent

$0.00

(0.00%)

WPP

WPP

$76.08

1.52 (2.04%)

03/08/13
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03/08/13
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03/06/13
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03/06/13
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  • 10

    Sep

AMZN

Amazon.com

$1,813.84

0.99 (0.05%)

, NFLX

Netflix

$361.33

-2.81 (-0.77%)

11:24
07/21/18
07/21
11:24
07/21/18
11:24
Periodicals
Amazon, Netflix to face tighter capital markets, Barron's says »

Since the Great…

AMZN

Amazon.com

$1,813.84

0.99 (0.05%)

NFLX

Netflix

$361.33

-2.81 (-0.77%)

TSLA

Tesla

$313.49

-6.85 (-2.14%)

03/08/13
Wedge Partners
03/08/13
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03/06/13
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03/06/13
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  • 26

    Jul

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    Aug

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    Aug

  • 16

    Aug

AB

AllianceBernstein

$29.90

-0.05 (-0.17%)

, BLK

BlackRock

$503.01

-1.42 (-0.28%)

11:17
07/21/18
07/21
11:17
07/21/18
11:17
Periodicals
BlackRock, T. Rowe Price look like bargains, Barron's says »

With shares of many…

AB

AllianceBernstein

$29.90

-0.05 (-0.17%)

BLK

BlackRock

$503.01

-1.42 (-0.28%)

BEN

Franklin Resources

$31.99

-0.28 (-0.87%)

IVZ

Invesco

$25.46

-0.245 (-0.95%)

LM

Legg Mason

$33.37

-0.13 (-0.39%)

TROW

T. Rowe Price

$119.87

-0.85 (-0.70%)

03/08/13
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  • 26

    Jul

  • 26

    Jul

  • 27

    Jul

ALV

Autoliv

$104.08

-0.57 (-0.54%)

, VNE

Veoneer

$50.81

-1.81 (-3.44%)

11:12
07/21/18
07/21
11:12
07/21/18
11:12
Periodicals
Automotive spinoffs offer exposure to autonomous, electric future, Barron's says »

Last month, Autoliv (ALV)…

ALV

Autoliv

$104.08

-0.57 (-0.54%)

VNE

Veoneer

$50.81

-1.81 (-3.44%)

DLPH

Delphi Technologies

$44.78

-0.355 (-0.79%)

APTV

Aptiv

$92.95

-2.02 (-2.13%)

03/08/13
Wedge Partners
03/08/13
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03/06/13
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03/06/13
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  • 31

    Jul

  • 08

    Aug

DDAIF

Daimler AG

$0.00

(0.00%)

, FCAU

Fiat Chrysler

$19.33

-0.195 (-1.00%)

07:58
07/21/18
07/21
07:58
07/21/18
07:58
Hot Stocks
Week in review: How Trump's policies moved stocks »

Catch up on the top…

DDAIF

Daimler AG

$0.00

(0.00%)

FCAU

Fiat Chrysler

$19.33

-0.195 (-1.00%)

F

Ford

$10.56

-0.115 (-1.08%)

GM

General Motors

$39.39

0.08 (0.20%)

HMC

Honda

$29.18

-0.19 (-0.65%)

NSANY

Nissan

$0.00

(0.00%)

TM

Toyota

$131.87

0.11 (0.08%)

VLKAY

Volkswagen

$0.00

(0.00%)

GOOG

Alphabet

$1,184.77

-2.37 (-0.20%)

GOOGL

Alphabet Class A

$1,198.05

-1.21 (-0.10%)

PFE

Pfizer

$37.33

-0.03 (-0.08%)

NVS

Novartis

$82.28

1.47 (1.82%)

RHHBY

Roche

$0.00

(0.00%)

SNY

Sanofi

$42.38

0.44 (1.05%)

BA

Boeing

$354.92

-0.57 (-0.16%)

MRK

Merck

$62.51

(0.00%)

03/08/13
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  • 22

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    Jul

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    Jul

  • 08

    Aug

  • 15

    Aug

  • 22

    Aug

  • 10

    Sep

  • 10

    Sep

  • 18

    Sep

  • 20

    Oct

  • 23

    Oct

  • 28

    Oct

  • 28

    Oct

  • 28

    Jan

  • 16

    Feb

  • 22

    Mar

ACN

Accenture

$166.47

-0.47 (-0.28%)

, EADSY

Airbus

$0.00

(0.00%)

04:55
07/21/18
07/21
04:55
07/21/18
04:55
Conference/Events
Farnborough International to hold an airshow »

Farnborough International…

ACN

Accenture

$166.47

-0.47 (-0.28%)

EADSY

Airbus

$0.00

(0.00%)

ATI

Allegheny Technologies

$26.65

0.08 (0.30%)

BAESY

BAE Systems

$0.00

(0.00%)

BDRBF

Bombardier

$0.00

(0.00%)

CAE

CAE

$20.96

0.17 (0.82%)

CW

Curtiss-Wright

$125.79

-0.12 (-0.10%)

DASTY

Dassault Systemes

$0.00

(0.00%)

ESLT

Elbit Systems

$118.98

0.64 (0.54%)

LMT

Lockheed Martin

$322.76

3.09 (0.97%)

BA

Boeing

$354.92

-0.57 (-0.16%)

03/08/13
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  • 24

    Jul

  • 24

    Jul

  • 25

    Jul

  • 26

    Jul

  • 30

    Jul

  • 02

    Aug

  • 06

    Aug

  • 16

    Aug

FNWB

First Northwest Bancorp

$16.11

0.36 (2.29%)

17:48
07/20/18
07/20
17:48
07/20/18
17:48
Hot Stocks
First Northwest Bancorp names Terry Anderson chief credit officer »

First Northwest Bancorp…

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FCX

Freeport McMoRan

$15.75

-0.05 (-0.32%)

17:42
07/20/18
07/20
17:42
07/20/18
17:42
Hot Stocks
Freeport McMoRan CAO Michael Arnold to retire »

In a regulatory filing,…

03/08/13
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XLE

Energy Select Sector SPDR

$74.87

-0.24 (-0.32%)

, XLU

Utilities SPDR

$52.28

-0.39 (-0.74%)

17:39
07/20/18
07/20
17:39
07/20/18
17:39
General news
Week ending ETF Scorecard: Financials lead, Energy slumps »

S&P500 SECTORS:…

XLE

Energy Select Sector SPDR

$74.87

-0.24 (-0.32%)

XLU

Utilities SPDR

$52.28

-0.39 (-0.74%)

IYR

DJ US Real Estate Index Fund

$80.23

-0.68 (-0.84%)

XLP

Consumer Staples Sector SPDR

$52.84

0.3 (0.57%)

XLY

Consumer Discretionary Sector SPDR

$112.15

-0.47 (-0.42%)

XLB

S&P Select Materials SPDR

$58.31

-0.21 (-0.36%)

XLF

Financial Select Sector

$27.57

0.065 (0.24%)

XLV

Health Care Select Sector SPDR

$86.74

-0.17 (-0.20%)

XLK

Technology Select Sector SPDR

$72.55

0.01 (0.01%)

XLI

Industrial Select Sector SPDR

$74.44

-0.09 (-0.12%)

GLD

SPDR Gold Trust

$116.56

0.74 (0.64%)

SLV

iShares Silver Trust

$14.59

0.18 (1.25%)

USO

United States Oil Fund

$14.15

0.025 (0.18%)

UNG

United States Natural Gas Fund

$22.38

-0.06 (-0.27%)

HYG

iShares iBoxx $ High Yield Corporate Bond

$85.62

0.03 (0.04%)

LQD

iShares iBoxx $ Investment Grade Corporate Bond

$115.27

-0.335 (-0.29%)

TLT

iShares 20+ Year Treasury Bond Fund

$120.78

-1.46 (-1.19%)

IEF

iShares 7-10 Year Treasury Bond ETF

$102.21

-0.35 (-0.34%)

SHY

iShares 1-3 Year Treasury Bond

$83.26

-0.005 (-0.01%)

IWD

iShares Russell 1000 Value

$123.07

-0.2897 (-0.23%)

IWF

iShares Russell 1000 Growth

$149.41

-0.04 (-0.03%)

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XRX

Xerox

$25.10

-0.095 (-0.38%)

, FUJIY

Fujifilm

$0.00

(0.00%)

17:25
07/20/18
07/20
17:25
07/20/18
17:25
Hot Stocks
Xerox, Centerview settle matters related to proposed Fuji tie-up »

On July 20, 2018, Xerox…

XRX

Xerox

$25.10

-0.095 (-0.38%)

FUJIY

Fujifilm

$0.00

(0.00%)

03/08/13
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  • 26

    Jul

STON

StoneMor Partners

$3.61

-0.015 (-0.41%)

17:15
07/20/18
07/20
17:15
07/20/18
17:15
Hot Stocks
Breaking Hot Stocks news story on StoneMor Partners »

Oaktree Capital reports…

03/08/13
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03/06/13
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03/06/13
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TEF

Telefonica

$8.70

0.07 (0.81%)

17:11
07/20/18
07/20
17:11
07/20/18
17:11
Downgrade
Telefonica rating change at Goldman Sachs »

Telefonica downgraded to…

03/08/13
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SPY

SPDR S&P 500 ETF Trust

$279.71

-0.24 (-0.09%)

, USO

United States Oil Fund

$14.15

0.025 (0.18%)

17:04
07/20/18
07/20
17:04
07/20/18
17:04
General news
Weekly CFTC Commitment of Traders highlights »

S&P500 net long 5.5K…

SPY

SPDR S&P 500 ETF Trust

$279.71

-0.24 (-0.09%)

USO

United States Oil Fund

$14.15

0.025 (0.18%)

GLD

SPDR Gold Trust

$116.56

0.74 (0.64%)

FXE

Euro Currency Trust

$112.46

0.83 (0.74%)

FXC

CurrencyShares Canadian Dollar Trust

$75.17

0.81 (1.09%)

03/08/13
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CZWI

Citizens Community Bancorp

$14.15

(0.00%)

17:02
07/20/18
07/20
17:02
07/20/18
17:02
Syndicate
Breaking Syndicate news story on Citizens Community Bancorp »

Citizens Community…

03/08/13
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PKD

Parker Drilling

$0.30

-0.0044 (-1.46%)

17:01
07/20/18
07/20
17:01
07/20/18
17:01
Hot Stocks
Breaking Hot Stocks news story on Parker Drilling »

Whitebox Advisors reports…

03/08/13
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  • 02

    Aug

RSLS

ReShape Lifesciences

$1.47

-0.02 (-1.34%)

17:00
07/20/18
07/20
17:00
07/20/18
17:00
Hot Stocks
Breaking Hot Stocks news story on ReShape Lifesciences  »

Intracoastal Capital…

03/08/13
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BOX

Box

$26.13

-0.26 (-0.99%)

16:57
07/20/18
07/20
16:57
07/20/18
16:57
Initiation
Box initiated at First Analysis »

Box initiated with an…

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ALDX

Aldeyra

$7.95

-0.15 (-1.85%)

16:53
07/20/18
07/20
16:53
07/20/18
16:53
Syndicate
Breaking Syndicate news story on Aldeyra »

Aldeyra files $250M mixed…

03/08/13
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GLRE

Greenlight Capital Re

$14.00

-0.15 (-1.06%)

16:46
07/20/18
07/20
16:46
07/20/18
16:46
Hot Stocks
Greenlight Capital Re announces departure of COO »

Greenlight Capital Ry…

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RVI

Retail Value

$34.56

0.2 (0.58%)

16:38
07/20/18
07/20
16:38
07/20/18
16:38
Hot Stocks
Breaking Hot Stocks news story on Retail Value »

Luxor Capital reports…

03/08/13
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