Genentech announces new Ocrevus data on long-term disability benefits in PPMS
Genentech, a member of the Roche Group, announced that new Ocrevus data will be presented at the 4th Congress of the European Academy of Neurology, EAN, from June 16-19 in Lisbon, Portugal. The new Phase III data analyses show Ocrevus may provide meaningful disability benefits such as delay in the need for a wheelchair for people with primary progressive multiple sclerosis, or PPMS. Genentech continues its commitment to people with progressive forms of MS by initiating two new global Phase IIIb studies that will evaluate the efficacy of OCREVUS in a broad range of people with progressive forms of MS. In a new exploratory analysis from the extended control period of the Phase III ORATORIO study in PPMS, OCREVUS may significantly delay the time to need a wheelchair by seven years, as measured by the length of time until a person reaches Expanded Disability Status Scale seven or greater using 24-week confirmed disability progression, or CDP. People treated with OCREVUS had a 46 percent reduction in the risk of progressing to a wheelchair compared to the placebo-treated group. When these results were extended to calculate the median time-to-wheelchair, the data suggest OCREVUS treatment may delay the need for a wheelchair by seven years.