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VSTM

Verastem

$6.53

0.95 (17.03%)

16:08
06/17/18
06/17
16:08
06/17/18
16:08

Verastem presents duvelisib data at EHA 2018 annual meeting

Verastem announced one oral and three poster presentations at the 23rd Congress of the European Hematology Association being held June 14-17, 2018 in Stockholm, Sweden. Data were presented on the company's lead product candidate, duvelisib, a first-in-class oral dual inhibitor of phosphoinositide 3-kinase-delta and PI3K-gamma. An oral presentation by Matthew Davids, Dana-Farber Cancer Institute, highlighted the latest data from a Phase Ib/II study evaluating duvelisib in combination with FCR as a frontline treatment in younger patients with chronic lymphocytic leukemia. Three poster presentations highlighted additional duvelisib data, including crossover extension results from the Phase 3 DUO study in patients with relapsed or refractory CLL/small lymphocytic lymphoma, and new biomarker analyses on the tumor microenvironment modulation from the DUOTM study and the Phase 2 DYNAMOTM study in patients with refractory indolent non-Hodgkin lymphoma, and the dual PI3K-delta and PI3K-gamma activity of duvelisib in the CONTEMPOTM study in patients with untreated follicular lymphoma who are treated with duvelisib in combination with CD20 antibody immunotherapy. Phase Ib/II study of duvelisib in combination with FCR [dFCR] achieved ORR of 94% and 76% bone marrow MRD negativity in frontline therapy in younger CLL patients. Duvelisib also demonstrated robust clinical activity in CLL with 73% ORR and a median of 15-month PFS in the DUO crossover study of patients who became relapsed/refractory to ofatumumab in DUO. Additional data support the hypothesis that duvelisib, a first-in-class dual inhibitor of PI3K delta/gamma, targets malignant B-cells directly and modulates the tumor microenvironment.

  • 05

    Oct

VSTM Verastem
$6.53

0.95 (17.03%)

03/08/18
RILY
03/08/18
INITIATION
Target $15
RILY
Buy
Verastem initiated with a Buy at B. Riley FBR
B. Riley FBR analyst George Zavoico started Verastem with a Buy rating and $15 price target. The analyst expects the company to "high the ground running" following the new drug application for duvelisib.
05/02/18
GHSC
05/02/18
INITIATION
Target $14
GHSC
Buy
Verastem initiated with a Buy at Seaport Global
Seaport Global analyst Corey Davis initiated Verastem with a Buy and $14 price target saying investors are giving little credit for duvelisib success, despite positive Phase 3 data in chronic lymphocytic leukemia, positive Phase 2 in fillicular lymphoma, and currently being under priority/accelerated FDA review.
06/06/18
06/06/18
NO CHANGE

Verastem mentioned positively by Agora
Ray Blanco of Breakthrough Technology Alert from Agora set a $15 price target on Verastem shares, according to contacts.
06/15/18
CANT
06/15/18
NO CHANGE
Target $17
CANT
Overweight
Verastem capital raise removes overhang, says Cantor Fitzgerald
Cantor Fitzgerald analyst Mara Goldstein believes Verastem's 7.1M share placement to a single institution removes an overhang on the shares. The raise bumps the company's cash to at least $140M, which will go a long way in removing an overhang on the shares ahead of the FDA action date of October 5, Goldstein tells investors in a research note. She continues to believe that the market for duvelisib is larger than Verastem's valuation suggests. Goldstein keeps an Overweight rating on the shares with a $17 price target.

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ITB

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CRNX

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IYR

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