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PTCT

PTC Therapeutics

$36.68

1.66 (4.74%)

16:12
07/19/18
07/19
16:12
07/19/18
16:12

PTC Therapeutics to acquire Agilis Biotherapeutics

PTC Therapeutics announced that it has entered into an agreement to acquire Agilis Biotherapeutics. The transaction was approved by the Boards of both companies. The transaction is expected to close in the third quarter of 2018, pending successful fulfillment of all customary closing conditions. On completion, PTC plans a smooth transition of operations and the integration of Agilis' talented and dedicated employees to continue the mission of bringing the pipeline of gene therapies for CNS disorders to patients worldwide. Under the terms of the merger agreement, PTC will pay an upfront consideration of $50M in cash and approximately $150M in PTC common stock, subject to an estimated maximum 9.34M share limit (with any shortfall to be made whole with additional cash consideration). In addition to the upfront payments, potential future consideration includes $60M in development milestones to be paid over the next two years which includes the acceptance of a BLA. Additionally, the transaction includes up to $535M in success-based milestones in connection with regulatory approvals on the three most advanced programs and receipt of a priority review voucher, as well as tiered commercial milestones of $150M, and 2-6 % of annual net sales for Friedreich ataxia and Angelman syndrome.

PTCT PTC Therapeutics
$36.68

1.66 (4.74%)

06/20/18
LEHM
06/20/18
DOWNGRADE
Target $45
LEHM
Underweight
Ionis Pharmaceuticals downgraded to Underweight from Equal Weight at Barclays
Barclays analyst Gena Wang downgraded Ionis Pharmaceuticals (IONS) to Underweight and lowered her price target for the shares to $45 from $52 after PTC Therapeutics (PTCT) reported competing spinal muscular atrophy data. Wang this morning also upgraded PTC to Equal Weight from Underweight.
06/20/18
LEHM
06/20/18
NO CHANGE
LEHM
Barclays upgrades PTC to Equal Weight, downgrades Ionis to Underweight
Barclays analyst Gena Wang upgraded PTC Therapeutics (PTCT) to Equal Weight from Underweight while downgrading Ionis Pharmaceuticals (IONS) to Underweight from Equal Weight. The analyst raised her price target on the former to $40 from $26 and lowered her price target on the latter to $45 from $52. Following PTC's new data in spinal muscular atrophy data, the analyst believes its risdiplam has "disruptive potential" to Ionis and Biogen's (BIIB) Spinraza.
06/20/18
WBLR
06/20/18
NO CHANGE
WBLR
Outperform
PTC Therapeutics weakness on Sarepta data overblown, says William Blair
William Blair analyst Raju Prasad believes the weakness in shares of PTC Therapeutics (PTCT) following Sarepta's (SRPT) micro-dystrophin gene therapy data is overblown. In a best-case scenario, the micro-dystrophin gene therapy could be approved in late 2021/early 2022 in the United States and potentially 2022/2023 in Europe, Prasad tells investors in a research note. As such, the analyst believes PTC management's projected five-year annual growth of 15% for Translarna due to increasing penetration in existing countries and potential label expansion remains likely. He still views Translarna and Emflaza revenues through 2022 plus cash on hand worth at least $35 per share, with $12 to $20 per share upside coming from risdiplam's potential in spinal muscular atrophy. Prasad keeps an Outperform rating on PTC Therapeutics.
07/19/18
FBCO
07/19/18
INITIATION
Target $49
FBCO
Outperform
PTC Therapeutics initiated with an Outperform at Credit Suisse
Credit Suisse initiated PTC Therapeutics with an Outperform and $49 price target.

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