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ONCE

Spark Therapeutics

$77.63

3.84 (5.20%)

07:51
08/07/18
08/07
07:51
08/07/18
07:51

Spark Therapeutics drops 25% to $58.44 following hemophilia data

  • 07

    Aug

  • 10

    Sep

ONCE Spark Therapeutics
$77.63

3.84 (5.20%)

07/16/18
CANT
07/16/18
NO CHANGE
Target $103
CANT
Overweight
Start of Pfizer trial encouraging for Spark Therapeutics, says Cantor Fitzgerald
After Spark Therapeutics (ONCE) announced that partner Pfizer (PFE) initiated a Phase 3 study to evaluate the efficacy and safety of current factor IX prophylaxis replacement therapy in the usual care setting, Cantor Fitzgerald analyst Elemer Piros said he was encouraged that the program transfer is on track and he remains bullish on the fidanacogene elaparvovec program. He reiterates his Overweight rating and $103 price target on Spark shares.
07/19/18
RBCM
07/19/18
DOWNGRADE
RBCM
Sector Perform
Spark Therapeutics downgraded to Sector Perform from Outperform at RBC Capital
07/19/18
RBCM
07/19/18
DOWNGRADE
Target $75
RBCM
Sector Perform
Spark Therapeutics cut to Sector Perform at RBC Capital on SPK-801 concern
As reported earlier, RBC Capital analyst Kennen MacKay downgraded Spark Therapeutics to Sector Perform from Outperform and kept his $75 price target. The analyst notes that after a strong run-up in the stock price driven by lofty expectations for the ongoing Phase 1/2 trial of SPK-8011 in patients with hemophilia, achieving mean FVIII expression levels of 30-55% anticipated by the Street could prove "challenging" as "data to date has not indicated clear dose responsiveness." McKay also cites the possibility of regulatory delays to gain approval for sale of Luxturna among the risks for Spark Therapeutics.
07/19/18
07/19/18
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Tesla (TSLA) downgraded to Underperform from Hold at Needham with analyst Rajvindra Gill saying the stock remains overvalued in spite of its 16% decline from the the June 2017 peak. 2. Procter & Gamble (PG) downgraded to Neutral from Buy at UBS with analyst Steven Strycula saying the company's reinvestment cycle limits earnings and stock upside. 3. Terex (TEX) downgraded to Market Perform from Outperform at Wells Fargo with analyst Andrew Casey saying his crane check was good but not great, with demand appearing to sequentially flatten. 4. Spark Therapeutics (ONCE) downgraded to Sector Perform from Outperform at RBC Capital with analyst Kennen MacKay saying that after a strong run-up in the stock price driven by lofty expectations for the ongoing Phase 1/2 trial of SPK-8011 in patients with hemophilia, achieving mean FVIII expression levels of 30-55% anticipated by the Street could prove "challenging" as "data to date has not indicated clear dose responsiveness." 5. Hyatt (H) downgraded to Hold from Buy at Berenberg with analyst El Kassir saying Hyatt continues to benchmark well on its pipeline, however, there is little scope for future growth to accelerate from current levels. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

ENTG

Entegris

$27.29

1.09 (4.16%)

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-0.79 (-3.11%)

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ECOM

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-0.12 (-1.14%)

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TCEHY

Tencent

$0.00

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, SPOT

Spotify

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2.99 (2.36%)

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$0.00

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SPOT

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UAL

United Continental

$91.76

-0.33 (-0.36%)

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United wins victory in Newark Airport fee dispute, WSJ reports »

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  • 27

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BGNE

BeiGene

$125.87

1.5 (1.21%)

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NMHLY

NMC Health

$0.00

(0.00%)

06:34
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NMC Health rating change  »

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ADI

Analog Devices

$89.12

3.57 (4.17%)

06:33
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  • 26

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AAPL

Apple

$177.10

-8.7 (-4.68%)

06:32
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Apple in talks to provide veterans access to electronic health records, WSJ says »

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  • 04

    Dec

SWGAY

Swatch Group

$0.00

(0.00%)

06:31
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Swatch Group rating change  »

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SWGAY

Swatch Group

$0.00

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DXCM

DexCom

$119.89

-1.34 (-1.11%)

, GOOG

Alphabet

$1,026.00

7 (0.69%)

06:28
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Recommendations
DexCom, Alphabet, Alphabet Class A analyst commentary  »

Amended Verily agreement…

DXCM

DexCom

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-1.34 (-1.11%)

GOOG

Alphabet

$1,026.00

7 (0.69%)

GOOGL

Alphabet Class A

$1,031.22

4.99 (0.49%)

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JD

JD.com

$19.49

-1.6 (-7.59%)

06:26
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JD.com 'Singles Day' fueled by illegal student labor, FT reports »

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BBY

Best Buy

$63.54

1.35 (2.17%)

06:26
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Best Buy rating change  »

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  • 05

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DE

Deere

$138.49

-4.04 (-2.83%)

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LOW

Lowe's

$86.15

-5.19 (-5.68%)

, HD

Home Depot

$169.17

-4.45 (-2.56%)

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LOW

Lowe's

$86.15

-5.19 (-5.68%)

HD

Home Depot

$169.17

-4.45 (-2.56%)

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BJ

BJ's Wholesale

$19.85

-0.22 (-1.10%)

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DNSKY

Danske Bank

$0.00

(0.00%)

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CMCO

Columbus McKinnon

$34.04

-0.56 (-1.62%)

06:21
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Conference/Events
Columbus McKinnon management to meet with Craig Hallum »

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  • 27

    Nov

DFS

Discover

$68.27

-1.315 (-1.89%)

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EMES

Emerge Energy

$2.73

0.03 (1.11%)

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DE

Deere

$138.49

-4.04 (-2.83%)

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CLGX

CoreLogic

$39.31

-0.32 (-0.81%)

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  • 27

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DE

Deere

$138.49

-4.04 (-2.83%)

06:15
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