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SPHS

Sophiris Bio

$2.57

-0.06 (-2.28%)

08:06
08/29/18
08/29
08:06
08/29/18
08:06

Sophiris Bio provides update on patient death in prostate cancer trial

Sophiris Bio announced the conclusion of the ongoing investigation into the previously reported death of a patient in the Company's Phase 2b trial for the treatment of localized prostate cancer is unlikely to be related to either topsalysin or the procedure. The regulatory authorities in the U.S. and the U.K. where the study is being conducted have been notified. Following a comprehensive review of the recently received autopsy report, together with hospital records and the negative serology results for acute hypersensitivity, the Investigator and company believe that the cause of death is consistent with the autopsy finding of Sudden Cardiac Death probably due to an arrhythmia. The autopsy found that the patient had multiple risk factors for SCD. The investigator and the company concur that the event is unlikely related to topsalysin or the procedure.

SPHS Sophiris Bio
$2.57

-0.06 (-2.28%)

06/25/18
MAXM
06/25/18
NO CHANGE
MAXM
Sophiris Bio's topsalysin remains a vaible PC drug candidate, says Maxim
Maxim analyst Jason McCarthy said Buy rated Sophiris Bio shares are being pressured by a patient death, which the cause remains unknown. The analyst said the data for single administration is positive and there have bee no safety issues. McCarthy continues to believe that topsalysin remains a viable PC drug candidate, but notes we have to wait on repeat administration data later in 2018 and a report on the patient.
06/25/18
PIPR
06/25/18
NO CHANGE
Target $7
PIPR
Overweight
Piper says Sophiris Bio 'worth sticking with' despite patient death in trial
A patient death after retreatment has "placed a cloud" over Sophiris Bio's topsalysin program despite efficacy data that was "clearly a home run," according to Piper Jaffray analyst Christopher Raymond. He sees a good chance the incident may end up not being categorized as drug-related, noting that topsalysin previously had shown a "pristine safety profile," and Raymond thinks the stock is "worth sticking with" at this point. The analyst, who is reserving judgment until more detail on topsalysin's role in the death is available, thinks there remains a credible path forward even if the death is deemed drug related. He keeps an Overweight rating and $7 price target on Sophiris shares, which fell about 40% to $2.24 today.
06/26/18
PIPR
06/26/18
NO CHANGE
Target $7
PIPR
Overweight
Sophiris Bio 'worth sticking with' after patient death, says Piper Jaffray
Piper Jaffray analyst Christopher Raymond maintained an Overweight rating and $7 price target on Sophiris Bio following disclosure of Phase 2b topsalysin data in localized prostate cancer. In a research note to investors, Raymond contended that while a patient death is "never a great headline," and that death after retreatment has now placed a cloud over the program, he thinks there is a good chance this incident may end up not being categorized as drug-related, and thinks it's worth "sticking with it here." Raymond sees a "credible" path forward with single administration, and urges investors to be patient on the name as clarity on the death and clinical path come more into focus.
08/14/18
PIPR
08/14/18
NO CHANGE
Target $7
PIPR
Overweight
Sophiris Bio topsalycin trial death disclosure imminent, says Piper Jaffray
Piper Jaffray analyst Christopher Raymond kept his Overweight rating and $7 price target on Sophiris Bio after its "uneventful" Q2 report. The analyst says that while the company did not update on the cause of death of one of its Phase 2b topsalycin trial patients, conversations with the management suggest that the disclosure is "imminent". Raymond adds that with the cause of death being announced, the "cloud" over the program will be lifted, allowing investors to focus on the drug's "impressive efficacy".

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MSM

MSC Industrial

$83.37

-0.44 (-0.52%)

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KFS

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AWK

American Water

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FSNN

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TISA

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FCPT

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PRK

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STNE

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GPIC

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SCHW

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MMNFF

MedMen

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TKC

Turkcell

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FCCY

1st Constitution Bancorp

$18.07

-0.14 (-0.77%)

11:05
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