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GBT

Global Blood Therapeutics

$35.15

-0.07 (-0.20%)

08:07
10/04/18
10/04
08:07
10/04/18
08:07

Global Blood Therapeutics to present three SCD abstracts at SCDAA

Global Blood Therapeutics announced that three abstracts related to its sickle cell disease, or SCD, development programs, including voxelotor, have been accepted for oral presentation during the annual National Sickle Cell Disease Association of America, or SCDAA.

GBT Global Blood Therapeutics
$35.15

-0.07 (-0.20%)

09/14/18
WBLR
09/14/18
NO CHANGE
WBLR
Outperform
William Blair sees 'high likelihood' of agreement between FDA, Global Blood
William Blair analyst Raju Prasad attributes the selloff yesterday in shares of Global Blood Therapeutics to a STAT report that discussed the risks associated with the company's regulatory strategy for voxelotor based on the novel hemoglobin endpoint. While the analyst agrees that there is some inherent risk to the company's approach, he also believes there is a "high likelihood" that Global Blood and the FDA will reach an agreement on a new drug application composition for an accelerated approval pathway. As such, Prasad believes the shares hold a positive risk/reward profile ahead of the company's regulatory strategy update and data presentation expected by the end of the year. He keeps an Outperform rating on Global Blood Therapeutics.
09/14/18
NOMU
09/14/18
NO CHANGE
Target $109
NOMU
Buy
Global Blood shares have 'significant upside' into end of 2018, says Nomura
After attending the Annual Sickle Cell Disease Therapeutics Conference, hosted by Global Blood Therapeutics, Nomura Instinet analyst Christopher Marai has a strengthened view that a voxelotor new drug application submission will occur by the end of 2018. Further, the company will likely receive accelerated approval based on data to date, Marai tells investors in a research note. The analyst recommends buying shares of Global Blood and believes the recent pullback is "unfounded" on the back of key takeaways from the SCD conference. He sees "significant upside" for the shares into a year-end NDA submission. Marai keeps a Buy rating on Global Blood Therapeutics with a $109 price target.
09/13/18
HCWC
09/13/18
NO CHANGE
Target $125
HCWC
Buy
H.C. Wainwright remains buyer of Global Blood Therapeutics on today's selloff
H.C. Wainwright analyst Debjit Chattopadhyay views the selloff today in shares of Global Blood Therapeutics as a buying opportunity. The analyst highlights "key mechanistic differences "between senicapoc and sildenafil, which he notes are often highlighted to further the bear argument of potentially increased risk of vaso-occlusive crisis with Global Blood's potential sickle cell disease treatment voxelotor. Unlike both senicapoc and sildenafil, 12-weeks treatment with voxelotor has translated into numerically fewer VOC events in Phase 2, Chattopadhyay tells investors in a research note titled "It's Deja Vu All Over Again." The analyst thinks Sarepta Therapeutics' (SRPT) Exnodys 51 approval "saga could serve as a good reference for voxelotor." While admitting he's not privy to the ongoing discussions between the FDA and Global Blood, Chattopadhyay continues to believe the agency is likely to embrace alternative endpoints over VOC as key secondary endpoints to the proposed confirmatory study for voxelotor. He continues to expect a potential rolling new drug application submission during mid-2019, with one-year safety data to be included as data matures. The analyst keeps a Buy rating on Global Blood Therapeutics with a $125 price target. The stock in late morning trading is down 9.5%, or $4.38, to $41.58 after STAT's Adam Feuerstein wrote the company's FDA filing plan "is riskier than you think."
08/23/18
PIPR
08/23/18
NO CHANGE
Target $80
PIPR
Overweight
Global Blood expands sickle cell disease portfolio, says Piper Jaffray
Global Blood Therapeutics announced this morning plans to in-license inclacumab, a fully human anti-P-selectin monoclonal antibody for the treatment of vaso-occlusive crises related to sickle cell disease, Piper Jaffray analyst Danielle Brill tells investors in a research note. Based on inclacumab's profile, the analyst expects it to demonstrate "robust efficacy and safety" for the prevention of vaso-occlusive crisis. The analyst keeps an Overweight rating on Global Blood with an $80 price target.

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