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ONCE

Spark Therapeutics

$49.35

0.76 (1.56%)

16:36
10/09/18
10/09
16:36
10/09/18
16:36

Spark Therapeutics initiated with a Buy at Guggenheim

Guggenheim analyst Whitney Ijem initiated Spark Therapeutics with a Buy rating and $70 price target. The analyst believes Spark's "in-house manufacturing capabilities and experience can be leveraged across the platform", as well as "provide strategic value as the interest/activity in gene therapy broadens."

  • 09

    Oct

ONCE Spark Therapeutics
$49.35

0.76 (1.56%)

08/08/18
BMOC
08/08/18
DOWNGRADE
Target $60
BMOC
Market Perform
Spark Therapeutics downgraded to Market Perform from Outperform at BMO Capital
As reported earlier, BMO Capital analyst Matthew Luchini downgraded Spark Therapeutics to Market Perform from Outperform and lowered his price target to $60 from $98. The analyst believes that the company's latest SPK-8011 hemA data falls short of expectations, with totality of the data suggesting a "less competitive profile versus valrox" and reducing his confidence in the program. Luchini notes that while Spark Therapeutics' Luxturna and hemB offer a valuation floor on the stock, there is little opportunity for upside.
08/08/18
RBCM
08/08/18
NO CHANGE
Target $64
RBCM
Sector Perform
Spark Therapeutics price target lowered to $64 from $75 at RBC Capital
RBC Capital analyst Kennen MacKay lowered his price target on Spark Therapeutics to $64 and kept his Sector Perform rating after its SPK-8011 update indicating lower than expected efficacy and safety profile. The analyst expects the stock to trade "choppy" going into the next round of update on the program at ASH, adding that he is also increasingly concerned about its phase-3 development path.
08/08/18
RHCO
08/08/18
NO CHANGE
Target $61
RHCO
Buy
Spark Therapeutics price target lowered to $61 from $102 at SunTrust
SunTrust analyst Edward Nash lowered his price target on Spark Therapeutics (ONCE) to $61, saying the company's SPK-8011 update has dimmed the outlook for its hemA program. Nash notes that while the FVIII activity reached the 30% threshold set by his physician consultants, it is below that of BioMarin (BMRN) BMN-270, adding the immune risk cannot be eliminated from the treatment. The analyst keeps his Buy rating on Spark Therapeutics, citing expectations of a gradual uptake of its Luxturna in 2018 with modeled commercial opportunity of $322M. Nash adds that Luxturna's commercial success should deepen the company's understanding of hemophilia and help differentiate its products from competitors.
08/08/18
08/08/18
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Aramark (ARMK) downgraded to Neutral from Outperform at Baird with analyst Andrew Wittmann saying the shares rallied following its results, which helped balance the risk/reward. 2. Hostess Brands (TWNK) downgraded to Sector Perform from Outperform at RBC Capital and to Hold from Buy at SunTrust. 3. Spark Therapeutics (ONCE) downgraded to Market Perform from Outperform at BMO Capital with analyst Matthew Luchini saying he believes that the company's latest SPK-8011 hemA data falls short of expectations, with totality of the data suggesting a "less competitive profile versus valrox" and reducing his confidence in the program. 4. Mallinckrodt (MNK) downgraded to Market Perform from Outperform at Raymond James with analyst Elliot WIlbur saying pipeline optionality remains high and is heavily discounted by valuation, and sees no "rational valuation framework" to support further upside. 5. Dentsply Sirona (XRAY) downgraded to Equal Weight from Overweight at Stephens and to Equal Weight from Overweight at Morgan Stanley. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

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WIN

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